{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T04:38:25Z","timestamp":1784608705703,"version":"3.55.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urology"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.urology.2012.09.004","type":"journal-article","created":{"date-parts":[[2012,11,30]],"date-time":"2012-11-30T01:16:42Z","timestamp":1354238202000},"page":"168-172","source":"Crossref","is-referenced-by-count":19,"title":["Is Urinary Kidney Injury Molecule-1 a Noninvasive Marker for Renal Scarring in Children With Vesicoureteral Reflux?"],"prefix":"10.1016","volume":"81","author":[{"given":"Aysun","family":"Toker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tevfik","family":"Ziypak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebru","family":"Orsal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"Laloglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fevzi","family":"Bedir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilmaz","family":"Aksoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2012.09.004_bib1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/BF02388714","article-title":"International system of radiographic grading of vesicoureteric reflux. International Reflux Study in Children","volume":"15","author":"Lebowitz","year":"1985","journal-title":"Pediatr Radiol"},{"key":"10.1016\/j.urology.2012.09.004_bib2","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1007\/s00467-004-1501-5","article-title":"Relationship between acute pyelonephritis, renal scarring, and vesicoureteral reflux. Results of a coordinated research project","volume":"19","author":"Orellana","year":"2004","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.urology.2012.09.004_bib3","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1007\/s00467-006-0063-0","article-title":"Ten-year results of randomized treatment of children with severe vesicoureteral reflux. Final report of the International Reflux Study in Children","volume":"21","author":"Jodal","year":"2006","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.urology.2012.09.004_bib4","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1136\/adc.70.2.111","article-title":"Renal scarring after acute pyelonephritis","volume":"70","author":"Jakobsson","year":"1994","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.urology.2012.09.004_bib5","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/S0003-4975(02)04559-9","article-title":"Is kidney function altered by the duration of cardiopulmonary bypass?","volume":"75","author":"Boldt","year":"2003","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.urology.2012.09.004_bib6","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1172\/JCI34487","article-title":"Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells","volume":"118","author":"Ichimura","year":"2008","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.urology.2012.09.004_bib7","doi-asserted-by":"crossref","first-page":"F1326","DOI":"10.1152\/ajprenal.00166.2002","article-title":"Kidney injury molecule-1 expression in murine polycystic kidney disease","volume":"283","author":"Kuehn","year":"2002","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.urology.2012.09.004_bib8","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1681\/ASN.2006030221","article-title":"Urinary N-acetyl-beta-(D)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure","volume":"18","author":"Liangos","year":"2007","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.urology.2012.09.004_bib9","doi-asserted-by":"crossref","first-page":"F517","DOI":"10.1152\/ajprenal.00291.2005","article-title":"Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of\u00a0kidney tubular injury","volume":"290","author":"Vaidya","year":"2006","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.urology.2012.09.004_bib10","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s004670050243","article-title":"The evaluation of acute pyelonephritis and renal scarring with technetium 99m-dimercaptosuccinic acid renal scintigraphy: evolving concepts and future directions","volume":"11","author":"Rushton","year":"1997","journal-title":"Pediatr Nephrol"},{"issue":"suppl 5","key":"10.1016\/j.urology.2012.09.004_bib11","doi-asserted-by":"crossref","first-page":"S240","DOI":"10.1542\/peds.2008-1285D","article-title":"Rationale and design issues of the Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR) study","volume":"122","author":"Keren","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.urology.2012.09.004_bib12","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/S0272-6386(86)80107-X","article-title":"Limitations of creatinine in quantifying the severity of cyclosporine-induced chronic nephropathy","volume":"8","author":"Tomlanovich","year":"1986","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.urology.2012.09.004_bib13","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1097\/01.ASN.0000129114.92265.32","article-title":"Discovery of protein biomarkers for renal diseases","volume":"15","author":"Hewitt","year":"2004","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.urology.2012.09.004_bib14","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s00281-003-0123-5","article-title":"New insights into mechanisms of fibrosis in immune renal injury","volume":"24","author":"Strutz","year":"2003","journal-title":"Springer Semin Immunopathol"},{"key":"10.1016\/j.urology.2012.09.004_bib15","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1056\/NEJM199411103311907","article-title":"Transforming growth factor beta in tissue fibrosis","volume":"331","author":"Border","year":"1994","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.urology.2012.09.004_bib16","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1038\/ki.1995.408","article-title":"Sequential changes in renal expression of renin-angiotensin system genes in acute unilateral ureteral obstruction","volume":"48","author":"Pimentel","year":"1995","journal-title":"Kidney Int"},{"issue":"suppl 3","key":"10.1016\/j.urology.2012.09.004_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1464-410x.1999.0830s3001.x","article-title":"Hypertension in reflux nephropathy","volume":"83","author":"Goonasekera","year":"1999","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2012.09.004_bib18","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/s00467-007-0723-8","article-title":"Laminin and transforming growth factor beta-1 in children with vesicoureteric reflux","volume":"23","author":"Sabasinska","year":"2008","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.urology.2012.09.004_bib19","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1161\/01.HYP.19.5.464","article-title":"Renal injury from angiotensin II-mediated hypertension","volume":"19","author":"Johnson","year":"1992","journal-title":"Hypertension"},{"key":"10.1016\/j.urology.2012.09.004_bib20","doi-asserted-by":"crossref","first-page":"F313","DOI":"10.1152\/ajprenal.00180.2006","article-title":"Induction of kidney injury molecule-1 in homozygous Ren2 rats is attenuated by blockade of the renin-angiotensin system or p38 MAP kinase","volume":"292","author":"de Borst","year":"2007","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.urology.2012.09.004_bib21","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1159\/000475367","article-title":"Renal pathology in patients with reflux nephropathy. The turning point in irreversible renal disease","volume":"26","author":"Matsuoka","year":"1994","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2012.09.004_bib22","doi-asserted-by":"crossref","first-page":"332","DOI":"10.3109\/13547501003706558","article-title":"Combination of urinary kidney injury molecule-1 and interleukin-18 as early biomarker for the diagnosis and progressive assessment of acute kidney injury following cardiopulmonary bypass surgery: a prospective nested case-control study","volume":"15","author":"Liang","year":"2010","journal-title":"Biomarkers"},{"key":"10.1016\/j.urology.2012.09.004_bib23","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1259\/bjr.72.856.10474494","article-title":"How sensitive is ultrasound in the detection of renal scars?","volume":"72","author":"Roebuck","year":"1999","journal-title":"Br J Radiol"},{"key":"10.1016\/j.urology.2012.09.004_bib24","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1159\/000475311","article-title":"Measurement of urinary endothelin-1-like immunoreactivity and comparison with other urinary parameters in patients with primary vesicoureteral reflux. A preliminary report","volume":"25","author":"Takeda","year":"1994","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2012.09.004_bib25","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.urology.2011.11.014","article-title":"Relationship between procalcitonin levels and presence of vesicoureteral reflux during first febrile urinary tract infection in children","volume":"79","author":"Ipek","year":"2012","journal-title":"Urology"},{"key":"10.1016\/j.urology.2012.09.004_bib26","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1007\/s00467-007-0477-3","article-title":"Serum and urine fibronectin levels in children with vesicoureteral reflux","volume":"22","author":"Sabasinska","year":"2007","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.urology.2012.09.004_bib27","doi-asserted-by":"crossref","first-page":"e356","DOI":"10.1542\/peds.2010-3467","article-title":"Urinary proteome analysis to exclude severe vesicoureteral reflux","volume":"129","author":"Drube","year":"2012","journal-title":"Pediatrics"},{"key":"10.1016\/j.urology.2012.09.004_bib28","first-page":"2001","article-title":"Urinary neutrophil-gelatinase associated lipocalin is a potential noninvasive marker for renal scarring in patients with vesicoureteral reflux","volume":"183","author":"Ichino","year":"2010","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2012.09.004_bib29","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/ki.2010.404","article-title":"Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-beta-D-glucosaminidase","volume":"79","author":"Vaidya","year":"2011","journal-title":"Kidney Int"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429512010709?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429512010709?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T06:50:48Z","timestamp":1714632648000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429512010709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0090429512010709"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2012.09.004","relation":{},"ISSN":["0090-4295"],"issn-type":[{"value":"0090-4295","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}