{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:50:28Z","timestamp":1789588228758,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","goldjournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1016\/j.urology.2015.03.007","type":"journal-article","created":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T12:16:11Z","timestamp":1435148171000},"page":"1454-1465","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["Animal Models of Urologic Chronic Pelvic Pain Syndromes: Findings From the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network"],"prefix":"10.1016","volume":"85","author":[{"given":"Henry","family":"Lai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5428-4251","authenticated-orcid":false,"suffix":"IV","given":"Robert W.","family":"Gereau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"O'Donnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles N.","family":"Rudick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Pontari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Mullins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Klumpp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2015.03.007_bib1","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1002\/nau.21078","article-title":"Models of inflammation of the lower urinary tract","volume":"30","author":"Bjorling","year":"2011","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2015.03.007_bib2","first-page":"694","article-title":"In\u00a0vivo models of interstitial cystitis","volume":"167","author":"Westropp","year":"2002","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2015.03.007_bib3","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1002\/nau.20903","article-title":"Animal models and their use in understanding lower urinary tract dysfunction","volume":"29","author":"Fry","year":"2010","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2015.03.007_bib4","first-page":"2162","article-title":"AUA guideline for the diagnosis and treatment of interstitial cystitis\/bladder pain syndrome","volume":"185","author":"Hanno","year":"2011","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2015.03.007_bib5","first-page":"1983","article-title":"Psychophysical evidence of hypersensitivity in subjects with interstitial cystitis","volume":"173","author":"Ness","year":"2005","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2015.03.007_bib6","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1016\/j.pain.2011.05.017","article-title":"Activation of spinal extracellular signal-regulated kinases (ERK) 1\/2 is associated with the development of visceral hyperalgesia of the bladder","volume":"152","author":"Lai","year":"2011","journal-title":"Pain"},{"key":"10.1016\/j.urology.2015.03.007_bib7","first-page":"1704","article-title":"Reliable visceromotor responses are evoked by noxious bladder distention in mice","volume":"171","author":"Ness","year":"2004","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2015.03.007_bib8","doi-asserted-by":"crossref","first-page":"G658","DOI":"10.1152\/ajpgi.00585.2005","article-title":"Convergence of sensory pathways in the development of somatic and visceral hypersensitivity","volume":"291","author":"Bielefeldt","year":"2006","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.urology.2015.03.007_bib9","first-page":"1373","article-title":"Sites of pain from interstitial cystitis\/painful bladder syndrome","volume":"180","author":"Warren","year":"2008","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2015.03.007_bib10","article-title":"Segmental hyperalgesia to mechanical stimulus in interstitial cystitis\/bladder pain syndrome\u2014evidence of central sensitization","author":"Lai","year":"2013","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2015.03.007_bib11","doi-asserted-by":"crossref","first-page":"R1191","DOI":"10.1152\/ajpregu.00411.2007","article-title":"Organ cross talk modulates pelvic pain","volume":"293","author":"Rudick","year":"2007","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.urology.2015.03.007_bib12","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0090-4295(01)01059-7","article-title":"Automated noninvasive measurement of cyclophosphamide-induced changes in murine micturition frequency and volume and demonstration of pharmacologic sensitivity","volume":"57","author":"Wood","year":"2001","journal-title":"Urology"},{"key":"10.1016\/j.urology.2015.03.007_bib13","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1002\/nau.21180","article-title":"Functional characterization of a chronic cyclophosphamide-induced overactive bladder model in mice","volume":"30","author":"Boudes","year":"2011","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2015.03.007_bib14","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1002\/nau.21108","article-title":"Rodent models for urodynamic investigation","volume":"30","author":"Andersson","year":"2011","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2015.03.007_bib15","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1086\/651275","article-title":"Host-pathogen interactions mediating pain of urinary tract infection","volume":"201","author":"Rudick","year":"2010","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.urology.2015.03.007_bib16","doi-asserted-by":"crossref","first-page":"e41273","DOI":"10.1371\/journal.pone.0041273","article-title":"O-antigen modulates infection-induced pain states","volume":"7","author":"Rudick","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.urology.2015.03.007_bib17","first-page":"343","article-title":"Protamine sulfate induced bladder injury protects from distention induced bladder pain","volume":"189","author":"Stemler","year":"2013","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2015.03.007_bib18","doi-asserted-by":"crossref","first-page":"e2096","DOI":"10.1371\/journal.pone.0002096","article-title":"Mast cell-derived histamine mediates cystitis pain","volume":"3","author":"Rudick","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.urology.2015.03.007_bib19","first-page":"715","article-title":"Gender specific pelvic pain severity in neurogenic cystitis","volume":"187","author":"Rudick","year":"2012","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2015.03.007_bib20","doi-asserted-by":"crossref","first-page":"539","DOI":"10.4049\/jimmunol.178.1.539","article-title":"Urinary bladder epithelium antigen induces CD8+ T cell tolerance, activation, and autoimmune response","volume":"178","author":"Liu","year":"2007","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.urology.2015.03.007_bib21","doi-asserted-by":"crossref","first-page":"46","DOI":"10.2460\/javma.1997.210.01.46","article-title":"Clinical evaluation of cats with nonobstructive urinary tract diseases","volume":"210","author":"Buffington","year":"1997","journal-title":"J\u00a0Am Vet Med Assoc"},{"key":"10.1016\/j.urology.2015.03.007_bib22","doi-asserted-by":"crossref","first-page":"967.e1","DOI":"10.1016\/j.urology.2011.06.041","article-title":"The effects of acute and chronic psychological stress on bladder function in a rodent model","volume":"78","author":"Smith","year":"2011","journal-title":"Urology"},{"key":"10.1016\/j.urology.2015.03.007_bib23","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.physbeh.2007.04.009","article-title":"Chronic psychological stress enhances nociceptive processing in the urinary bladder in high-anxiety rats","volume":"91","author":"Robbins","year":"2007","journal-title":"Physiol Behav"},{"key":"10.1016\/j.urology.2015.03.007_bib24","doi-asserted-by":"crossref","first-page":"R147","DOI":"10.1152\/ajpregu.00089.2013","article-title":"Repeated variate stress in male rats induces increased voiding frequency, somatic sensitivity, and urinary bladder nerve growth factor expression","volume":"305","author":"Merrill","year":"2013","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.urology.2015.03.007_bib25","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0090-4295(01)01166-9","article-title":"Biopsy features are associated with primary symptoms in interstitial cystitis: results from the interstitial cystitis database study","volume":"57","author":"Tomaszewski","year":"2001","journal-title":"Urology"},{"key":"10.1016\/j.urology.2015.03.007_bib26","first-page":"1908","article-title":"Comparison of cystoscopic and histological findings in patients with suspected interstitial cystitis","volume":"164","author":"Denson","year":"2000","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2015.03.007_bib27","first-page":"1008","article-title":"Characterization of cyclophosphamide cystitis, a model of visceral and referred pain, in the mouse: species and strain differences","volume":"170","author":"Bon","year":"2003","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2015.03.007_bib28","first-page":"21","article-title":"Urine levels of selected chemokines positively correlate with lower bladder capacity and psychometric scores in IC\/BPS patients","volume":"181","author":"Tyagi","year":"2009","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.urology.2015.03.007_bib29","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.urology.2007.12.091","article-title":"Urinary tract infection and inflammation at onset of interstitial cystitis\/painful bladder syndrome","volume":"71","author":"Warren","year":"2008","journal-title":"Urology"},{"key":"10.1016\/j.urology.2015.03.007_bib30","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1464-410X.2011.10766.x","article-title":"Evidence of bladder oversensitivity in the absence of an infection in premenopausal women with a history of recurrent urinary tract infections","volume":"110","author":"Arya","year":"2012","journal-title":"BJU Int"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429515002472?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429515002472?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,9]],"date-time":"2024-06-09T13:53:48Z","timestamp":1717941228000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429515002472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S0090429515002472"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2015.03.007","relation":{},"ISSN":["0090-4295"],"issn-type":[{"value":"0090-4295","type":"print"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Animal Models of Urologic Chronic Pelvic Pain Syndromes: Findings From the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network","name":"articletitle","label":"Article Title"},{"value":"Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urology.2015.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}