{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T19:38:23Z","timestamp":1793216303660,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81270693"],"award-info":[{"award-number":["81270693"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81470921"],"award-info":[{"award-number":["81470921"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81272531"],"award-info":[{"award-number":["81272531"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","goldjournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.urology.2015.07.026","type":"journal-article","created":{"date-parts":[[2015,9,14]],"date-time":"2015-09-14T18:22:12Z","timestamp":1442254932000},"page":"1241.e11-1241.e18","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":61,"title":["Low-intensity Pulsed Ultrasound Improves Erectile Function in Streptozotocin-induced Type I Diabetic Rats"],"prefix":"10.1016","volume":"86","author":[{"given":"Hongen","family":"Lei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Xin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruili","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongde","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huixi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjie","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhezhu","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinglu","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom F.","family":"Lue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiting","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongcheng","family":"Xin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2015.07.026_bib1","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.eururo.2013.08.023","article-title":"A\u00a0systematic review of the association between erectile dysfunction and cardiovascular disease","volume":"65","author":"Gandaglia","year":"2014","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2015.07.026_bib2","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jdiacomp.2010.03.003","article-title":"Diabetes-induced erectile dysfunction: epidemiology, pathophysiology and management","volume":"25","author":"Thorve","year":"2011","journal-title":"J\u00a0Diabetes Complications"},{"key":"10.1016\/j.urology.2015.07.026_bib3","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1016\/j.jacc.2008.02.051","article-title":"Erectile dysfunction predicts coronary heart disease in type 2 diabetes","volume":"51","author":"Ma","year":"2008","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.urology.2015.07.026_bib4","first-page":"832","article-title":"Effects of icariside II on improving erectile function in rats with streptozotocin-induced diabetes","volume":"33","author":"Zhou","year":"2012","journal-title":"J\u00a0Androl"},{"key":"10.1016\/j.urology.2015.07.026_bib5","first-page":"2439","article-title":"Therapeutic potential of adipose-derived stem cells-based micro-tissues in a rat model of postprostatectomy erectile dysfunction","volume":"11","author":"Xu","year":"2014","journal-title":"J\u00a0Sex Med"},{"key":"10.1016\/j.urology.2015.07.026_bib6","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1517\/14712598.2013.847085","article-title":"Stem-cell therapy for erectile dysfunction","volume":"13","author":"Lin","year":"2013","journal-title":"Expert Opin Biol Ther"},{"key":"10.1016\/j.urology.2015.07.026_bib7","first-page":"1522","article-title":"Scaffoldless tissue engineering of stem cell derived cavernous tissue for treatment of erectile function","volume":"9","author":"Orabi","year":"2012","journal-title":"J\u00a0Sex Med"},{"key":"10.1016\/j.urology.2015.07.026_bib8","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0022-2836(02)00427-8","article-title":"A\u00a0revolutionary landscape: the restructuring of biology and its convergence with medicine","volume":"319","author":"Kafatos","year":"2002","journal-title":"J\u00a0Mol Biol"},{"key":"10.1016\/j.urology.2015.07.026_bib9","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.eururo.2010.04.004","article-title":"Can low-intensity extracorporeal shockwave therapy improve erectile function? A 6-month follow-up pilot study in patients with organic erectile dysfunction","volume":"58","author":"Vardi","year":"2010","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2015.07.026_bib10","first-page":"738","article-title":"Effects of low-energy shockwave therapy on the erectile function and tissue of a diabetic rat model","volume":"10","author":"Qiu","year":"2013","journal-title":"J\u00a0Sex Med"},{"key":"10.1016\/j.urology.2015.07.026_bib11","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.expneurol.2012.04.019","article-title":"Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat","volume":"236","author":"Hausner","year":"2012","journal-title":"Exp Neurol"},{"key":"10.1016\/j.urology.2015.07.026_bib12","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0929-8266(99)00013-0","article-title":"Therapeutic ultrasound","volume":"9","author":"ter Haar","year":"1999","journal-title":"Eur J Ultrasound"},{"key":"10.1016\/j.urology.2015.07.026_bib13","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.jhsa.2012.11.032","article-title":"Effect of low-intensity pulsed ultrasound on bone healing at osteotomy sites after forearm bone shortening","volume":"38","author":"Urita","year":"2013","journal-title":"J\u00a0Hand Surg"},{"key":"10.1016\/j.urology.2015.07.026_bib14","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1111\/j.1600-0765.2007.01016.x","article-title":"Low-intensity pulsed ultrasound accelerates periodontal wound healing after flap surgery","volume":"43","author":"Ikai","year":"2008","journal-title":"J\u00a0Periodontal Res"},{"key":"10.1016\/j.urology.2015.07.026_bib15","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.bone.2013.09.018","article-title":"Low-intensity pulsed ultrasound (LIPUS) inhibits LPS-induced inflammatory responses of osteoblasts through TLR4-MyD88 dissociation","volume":"58","author":"Nakao","year":"2014","journal-title":"Bone"},{"key":"10.1016\/j.urology.2015.07.026_bib16","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1093\/cvr\/cvs173","article-title":"Ultrasound stimulation restores impaired neovascularization-related capacities of human circulating angiogenic cells","volume":"95","author":"Toyama","year":"2012","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.urology.2015.07.026_bib17","doi-asserted-by":"crossref","first-page":"e104863","DOI":"10.1371\/journal.pone.0104863","article-title":"Low-intensity pulsed ultrasound induces angiogenesis and ameliorates left ventricular dysfunction in a porcine model of chronic myocardial ischemia","volume":"9","author":"Hanawa","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.urology.2015.07.026_bib18","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1038\/ijir.2014.14","article-title":"Measurement of endothelial dysfunction via peripheral arterial tonometry predicts vasculogenic erectile dysfunction","volume":"26","author":"Kovac","year":"2014","journal-title":"Int J Impot Res"},{"key":"10.1016\/j.urology.2015.07.026_bib19","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1177\/1479164113508564","article-title":"Investigation of endothelial dysfunction and arterial stiffness in children with type 1 diabetes mellitus and the association with diastolic dysfunction","volume":"11","author":"Ciftel","year":"2014","journal-title":"Diab Vasc Dis Res"},{"key":"10.1016\/j.urology.2015.07.026_bib20","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jdiacomp.2011.12.001","article-title":"Erectile dysfunction and its association with metabolic syndrome and endothelial function among patients with type 2 diabetes mellitus","volume":"26","author":"Ryan","year":"2012","journal-title":"J\u00a0Diabetes its Complications"},{"key":"10.1016\/j.urology.2015.07.026_bib21","first-page":"758","article-title":"Diabetes exacerbates the functional deficiency of NO\/cGMP pathway associated with erectile dysfunction in human corpus cavernosum and penile arteries","volume":"7","author":"Angulo","year":"2010","journal-title":"J\u00a0Sex Med"},{"issue":"suppl 3","key":"10.1016\/j.urology.2015.07.026_bib22","first-page":"353","article-title":"Mechanisms of penile fibrosis","volume":"6","author":"Gonzalez-Cadavid","year":"2009","journal-title":"J\u00a0Sex Med"},{"key":"10.1016\/j.urology.2015.07.026_bib23","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1111\/j.1464-410X.2008.08251.x","article-title":"Early onset of fibrosis within the arterial media in a rat model of type 2 diabetes mellitus with erectile dysfunction","volume":"103","author":"Kovanecz","year":"2009","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2015.07.026_bib24","first-page":"1454","article-title":"Increased cavernous expression of transforming growth factor-beta1 and activation of the Smad signaling pathway affects erectile dysfunction in men with spinal cord injury","volume":"8","author":"Shin","year":"2011","journal-title":"J\u00a0Sex Med"},{"key":"10.1016\/j.urology.2015.07.026_bib25","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1111\/j.1464-410X.2011.10397.x","article-title":"Amelioration of diabetes-induced cavernosal fibrosis by antioxidant and anti-transforming growth factor-beta1 therapies in inducible nitric oxide synthase-deficient mice","volume":"109","author":"Ferrini","year":"2012","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2015.07.026_bib26","first-page":"2942","article-title":"P144, A TGF-beta1 antagonist peptide, synergizes with sildenafil and enhances erectile response via amelioration of cavernosal fibrosis in diabetic rats","volume":"10","author":"Li","year":"2013","journal-title":"J\u00a0Sex Med"},{"key":"10.1016\/j.urology.2015.07.026_bib27","doi-asserted-by":"crossref","first-page":"208","DOI":"10.5534\/wjmh.2013.31.3.208","article-title":"Low-intensity shock wave therapy and its application to erectile dysfunction","volume":"31","author":"Lei","year":"2013","journal-title":"World J men's Health"},{"key":"10.1016\/j.urology.2015.07.026_bib28","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1093\/bmb\/ldn040","article-title":"The effects of LIPUS on soft-tissue healing: a review of literature","volume":"89","author":"Khanna","year":"2009","journal-title":"Br Med Bull"},{"key":"10.1016\/j.urology.2015.07.026_bib29","doi-asserted-by":"crossref","first-page":"10661","DOI":"10.3390\/ijms140510661","article-title":"Evaluation of the effect of different doses of low energy shock wave therapy on the erectile function of streptozotocin (STZ)-induced diabetic rats","volume":"14","author":"Liu","year":"2013","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.urology.2015.07.026_bib30","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1089\/scd.2014.0380","article-title":"Implications for differentiation of endogenous stem cells: therapeutic effect from icariside II on a rat model of postprostatectomy erectile dysfunction","volume":"24","author":"Xu","year":"2015","journal-title":"Stem Cells Dev"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429515007074?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429515007074?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T13:14:33Z","timestamp":1620825273000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429515007074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S0090429515007074"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2015.07.026","relation":{},"ISSN":["0090-4295"],"issn-type":[{"value":"0090-4295","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low-intensity Pulsed Ultrasound Improves Erectile Function in Streptozotocin-induced Type I Diabetic Rats","name":"articletitle","label":"Article Title"},{"value":"Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urology.2015.07.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}