{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:13:39Z","timestamp":1762899219970},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","goldjournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.urology.2015.12.041","type":"journal-article","created":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T07:00:26Z","timestamp":1453273226000},"page":"15-21","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Management of Penile Cancer"],"prefix":"10.1016","volume":"96","author":[{"given":"Gregory J.","family":"Diorio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew R.","family":"Leone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe E.","family":"Spiess","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2015.12.041_bib0010","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3322\/caac.21208","article-title":"Cancer statistics, 2014","volume":"64","author":"Siegel","year":"2014","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.urology.2015.12.041_bib0015","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/j.eururo.2010.01.039","article-title":"EAU penile cancer guidelines 2009","volume":"57","author":"Pizzocaro","year":"2010","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0020","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1136\/jclinpath-2015-202911","article-title":"Review of in situ and invasive penile squamous cell carcinoma and associated non-neoplastic dermatological conditions","volume":"68","author":"Downes","year":"2015","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.urology.2015.12.041_bib0025","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.eururo.2014.10.017","article-title":"EAU guidelines on penile cancer: 2014 update","volume":"67","author":"Hakenberg","year":"2015","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0030","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/jso.20414","article-title":"Prognostic factors in node-positive carcinoma of the penis","volume":"93","author":"Pandey","year":"2006","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.urology.2015.12.041_bib0035","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/S0022-5347(17)44281-9","article-title":"Penile cancer: relation of extent of nodal metastasis to survival","volume":"137","author":"Srinivas","year":"1987","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0040","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1002\/ijc.21009","article-title":"Penile cancer: importance of circumcision, human papillomavirus and smoking in in situ and invasive disease","volume":"116","author":"Daling","year":"2005","journal-title":"Int J Cancer"},{"key":"10.1016\/j.urology.2015.12.041_bib0045","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.urolonc.2013.06.012","article-title":"Human papillomaviruses in urological malignancies: a critical assessment","volume":"32","author":"Tolstov","year":"2014","journal-title":"Urol Oncol"},{"key":"10.1016\/j.urology.2015.12.041_bib0050","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.urolonc.2013.08.010","article-title":"Implications for human papillomavirus in penile cancer","volume":"32","author":"Flaherty","year":"2014","journal-title":"Urol Oncol"},{"key":"10.1016\/j.urology.2015.12.041_bib0055","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s00345-008-0315-7","article-title":"The role of pathologic prognostic factors in squamous cell carcinoma of the penis","volume":"27","author":"Cubilla","year":"2009","journal-title":"World J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0060","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1097\/01.ju.0000154565.37397.4d","article-title":"Patients with penile carcinoma benefit from immediate resection of clinically occult lymph node metastases","volume":"173","author":"Kroon","year":"2005","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0065","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1159\/000475360","article-title":"Prophylactic bilateral groin node dissection versus prophylactic radiotherapy and surveillance in patients with N0 and N1-2A carcinoma of the penis","volume":"26","author":"Kulkarni","year":"1994","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0070","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1111\/iju.12759","article-title":"Prognostic factors in patients with penile carcinoma and inguinal lymph node metastasis","volume":"22","author":"da Costa","year":"2015","journal-title":"Int J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0075","series-title":"AJCC Cancer Staging Manual","author":"Edge","year":"2010"},{"key":"10.1016\/j.urology.2015.12.041_bib0080","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0094-0143(21)00390-6","article-title":"Penile amputations for the management of primary carcinoma of the penis","volume":"19","author":"Das","year":"1992","journal-title":"Urol Clin North Am"},{"key":"10.1016\/j.urology.2015.12.041_bib0085","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1111\/j.1524-4725.1980.tb01026.x","article-title":"Cancers, precancers, and pseudocancers on the male genitalia. A review of clinical appearances, histopathology, and management","volume":"6","author":"Mikhail","year":"1980","journal-title":"J Dermatol Surg Oncol"},{"key":"10.1016\/j.urology.2015.12.041_bib0090","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1111\/j.1464-410X.2005.05769.x","article-title":"What surgical resection margins are required to achieve oncological control in men with primary penile cancer?","volume":"96","author":"Minhas","year":"2005","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2015.12.041_bib0095","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.eururo.2008.04.016","article-title":"Recurrence patterns of squamous cell carcinoma of the penis: recommendations for follow-up based on a two-centre analysis of 700 patients","volume":"54","author":"Leijte","year":"2008","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0100","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1111\/bju.12338","article-title":"Penile cancer: organ-sparing techniques","volume":"114","author":"Hegarty","year":"2014","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2015.12.041_bib0105","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.juro.2013.12.038","article-title":"Penile sparing surgery for penile cancer-does it affect survival?","volume":"192","author":"Djajadiningrat","year":"2014","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0110","doi-asserted-by":"crossref","first-page":"594","DOI":"10.6004\/jnccn.2013.0075","article-title":"Penile cancer: clinical practice guidelines in oncology","volume":"11","author":"Clark","year":"2013","journal-title":"J Natl Compr Canc Netw"},{"key":"10.1016\/j.urology.2015.12.041_bib0115","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.eururo.2012.02.052","article-title":"Treatment of carcinoma in situ of the glans penis with topical chemotherapy agents","volume":"62","author":"Alnajjar","year":"2012","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0120","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.eururo.2010.09.039","article-title":"Glans resurfacing for the treatment of carcinoma in situ of the penis: surgical technique and outcomes","volume":"59","author":"Shabbir","year":"2011","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0125","doi-asserted-by":"crossref","first-page":"240824","DOI":"10.1155\/2011\/240824","article-title":"Outcome of glansectomy and skin grafting in the management of penile cancer","volume":"2011","author":"O'Kane","year":"2011","journal-title":"Adv Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0130","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1111\/j.1464-410X.2009.09188.x","article-title":"Organ-preserving neodymium-yttrium-aluminium-garnet laser therapy for penile carcinoma: a long-term follow-up","volume":"106","author":"Schlenker","year":"2010","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2015.12.041_bib0135","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1016\/j.juro.2007.07.039","article-title":"Mohs micrographic surgery for penile cancer: management and long-term followup","volume":"178","author":"Shindel","year":"2007","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0140","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1111\/j.1464-410X.1994.tb09200.x","article-title":"Quality of life in patients treated for penile cancer. A follow-up study","volume":"74","author":"Opjordsmoen","year":"1994","journal-title":"Br J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0145","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1111\/j.1464-410X.2009.08424.x","article-title":"Total phallic reconstruction after penile amputation for carcinoma","volume":"104","author":"Garaffa","year":"2009","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2015.12.041_bib0150","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.brachy.2014.06.003","article-title":"High-dose-rate interstitial brachytherapy for T1-T2-stage penile carcinoma: short-term results","volume":"13","author":"Sharma","year":"2014","journal-title":"Brachytherapy"},{"key":"10.1016\/j.urology.2015.12.041_bib0155","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.currproblcancer.2015.03.007","article-title":"The role of radiotherapy in the management of penile cancer","volume":"39","author":"Crook","year":"2015","journal-title":"Curr Probl Cancer"},{"key":"10.1016\/j.urology.2015.12.041_bib0160","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.eururo.2009.07.004","article-title":"Lymph node metastasis in intermediate-risk penile squamous cell cancer: a two-centre experience","volume":"57","author":"Hughes","year":"2010","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0165","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/S0022-5347(17)41589-8","article-title":"Modified inguinal lymphadenectomy for carcinoma of the penis with preservation of saphenous veins: technique and preliminary results","volume":"140","author":"Catalona","year":"1988","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0170","doi-asserted-by":"crossref","first-page":"3325","DOI":"10.1200\/JCO.2008.20.6870","article-title":"Two-center evaluation of dynamic sentinel node biopsy for squamous cell carcinoma of the penis","volume":"27","author":"Leijte","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.urology.2015.12.041_bib0175","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.juro.2011.09.058","article-title":"Accuracy of sentinel lymph node biopsy for inguinal lymph node staging of penile squamous cell carcinoma: systematic review and meta-analysis of the literature","volume":"187","author":"Sadeghi","year":"2012","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0180","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1016\/j.juro.2007.01.125","article-title":"Preoperative lymphoscintigraphy and dynamic sentinel node biopsy for staging penile cancer: results with pathological correlation","volume":"177","author":"Spiess","year":"2007","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0185","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1089\/end.2007.0386","article-title":"Can video endoscopic inguinal lymphadenectomy achieve a lower morbidity than open lymph node dissection in penile cancer patients?","volume":"22","author":"Tobias-Machado","year":"2008","journal-title":"J Endourol"},{"key":"10.1016\/j.urology.2015.12.041_bib0190","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1111\/j.1464-410X.2012.11729.x","article-title":"Phase 1 prospective evaluation of the oncological adequacy of robotic assisted video-endoscopic inguinal lymphadenectomy in patients with penile carcinoma","volume":"111","author":"Matin","year":"2013","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2015.12.041_bib0195","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.eururo.2009.02.021","article-title":"Lymphadenectomy in the surgical management of penile cancer","volume":"55","author":"Protzel","year":"2009","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0200","first-page":"141","article-title":"Skin excision and groin lymphadenectomy: techniques and outcomes","volume":"39","author":"Kean","year":"2006","journal-title":"Lymphology"},{"key":"10.1016\/j.urology.2015.12.041_bib0205","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.urolonc.2011.02.020","article-title":"Update in the surgical principles and therapeutic outcomes of inguinal lymph node dissection for penile cancer","volume":"31","author":"Ercole","year":"2013","journal-title":"Urol Oncol"},{"key":"10.1016\/j.urology.2015.12.041_bib0210","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.eururo.2003.12.003","article-title":"Morbidity of inguinal lymphadenectomy for invasive penile carcinoma","volume":"45","author":"Bouchot","year":"2004","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0215","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/bju.13009","article-title":"Predicting postoperative complications of inguinal lymph node dissection for penile cancer in an international multicentre cohort","volume":"116","author":"Gopman","year":"2015","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2015.12.041_bib0220","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1016\/j.juro.2014.12.019","article-title":"Prophylactic pelvic lymph node dissection in patients with penile cancer","volume":"193","author":"Djajadiningrat","year":"2015","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0225","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.urolonc.2015.05.008","article-title":"Adjuvant chemotherapy is associated with improved overall survival in pelvic node-positive penile cancer after lymph node dissection: a multi-institutional study","volume":"33","author":"Sharma","year":"2015","journal-title":"Urol Oncol"},{"key":"10.1016\/j.urology.2015.12.041_bib0230","doi-asserted-by":"crossref","first-page":"3851","DOI":"10.1200\/JCO.2010.29.5477","article-title":"Neoadjuvant paclitaxel, ifosfamide, and cisplatin chemotherapy for metastatic penile cancer: a phase II study","volume":"28","author":"Pagliaro","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.urology.2015.12.041_bib0235","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.juro.2014.02.2563","article-title":"Salvage surgical resection for isolated locally recurrent inguinal lymph node metastasis of penile cancer: international study collaboration","volume":"192","author":"Baumgarten","year":"2014","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2015.12.041_bib0240","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1111\/j.1464-410X.2006.06496.x","article-title":"Cisplatin, methotrexate and bleomycin for treating advanced penile carcinoma","volume":"98","author":"Hakenberg","year":"2006","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2015.12.041_bib0245","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1111\/bju.12450","article-title":"Epidermal growth factor receptor-targeted therapy in locally advanced or metastatic squamous cell carcinoma of the penis","volume":"113","author":"Carthon","year":"2014","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2015.12.041_bib0250","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1200\/JCO.2014.58.9093","article-title":"Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells","volume":"33","author":"Stevanovic","year":"2015","journal-title":"J Clin Oncol"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429515011966?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429515011966?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:34:44Z","timestamp":1654130084000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429515011966"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":49,"alternative-id":["S0090429515011966"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2015.12.041","relation":{},"ISSN":["0090-4295"],"issn-type":[{"value":"0090-4295","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Management of Penile Cancer","name":"articletitle","label":"Article Title"},{"value":"Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urology.2015.12.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}