{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:40:09Z","timestamp":1792176009841,"version":"4.4.0"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","goldjournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.urology.2020.03.007","type":"journal-article","created":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T12:40:37Z","timestamp":1584621637000},"page":"7-13","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Use of Botulinum Toxin A (BoNT-A) in Detrusor External Sphincter Dyssynergia (DESD): A Systematic Review and Meta-analysis"],"prefix":"10.1016","volume":"140","author":[{"given":"Shokhi","family":"Goel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hudson","family":"Pierce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6923-1945","authenticated-orcid":false,"given":"Kevin","family":"Pain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Christos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Dmochowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilal","family":"Chughtai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2020.03.007_bib0001","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0090-4295(02)02243-4","article-title":"The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society","volume":"61","author":"Abrams","year":"2003","journal-title":"Urology"},{"key":"10.1016\/j.urology.2020.03.007_bib0002","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1464-410X.2012.11042.x","article-title":"Diagnosing detrusor sphincter dyssynergia in the neurological patient","author":"Bacsu","year":"2012","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2020.03.007_bib0003","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/S0022-5347(17)54147-6","article-title":"The neurophysiology of micturition: a clinical study of 550 patients","volume":"127","author":"Blaivas","year":"1982","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0004","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0022-5347(17)50216-5","article-title":"Detrusor-external sphincter dyssynergia in men with multiple sclerosis: an ominous urologic condition","volume":"131","author":"Blaivas","year":"1984","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0005","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1136\/jnnp.49.5.554","article-title":"Urethro-vesical dysfunction in progressive autonomic failure with multiple system atrophy","volume":"49","author":"Kirby","year":"1986","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.urology.2020.03.007_bib0006","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0022-5347(17)55100-9","article-title":"Detrusor-external sphincter dyssynergia: a detailed electromyographic study","volume":"125","author":"Blaivas","year":"1981","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0007","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/S1474-4422(15)00070-8","article-title":"Lower urinary tract dysfunction in the neurological patient: clinical assessment and management","volume":"14","author":"Panicker","year":"2015","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.urology.2020.03.007_bib0008","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/nrn2401","article-title":"The neural control of micturition","volume":"9","author":"Fowler","year":"2008","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.urology.2020.03.007_bib0009","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/S0022-5347(17)58286-5","article-title":"Detrusor-urethral sphincter dyssynergia","volume":"118","author":"Yalla","year":"1977","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0010","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/S0022-5347(17)37254-3","article-title":"Risk factors for upper tract deterioration in chronic spinal cord injury patients","volume":"147","author":"Gerridzen","year":"1992","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0011","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1002\/nau.21003","article-title":"Epidemiology and healthcare utilization of neurogenic bladder patients in a US claims database","volume":"30","author":"Manack","year":"2011","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2020.03.007_bib0012","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S0022-5347(17)61055-3","article-title":"Clean, intermittent self-catheterization in the treatment of urinary tract disease","volume":"107","author":"Lapides","year":"1972","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0013","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/nau.1930140106","article-title":"External urethral sphincterotomy: long-term follow-up","volume":"14","author":"Yang","year":"1995","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2020.03.007_bib0014","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S0022-5347(01)63957-0","article-title":"Bladder leak point pressure: the measure for sphincterotomy success in spinal cord injured patients with external detrusor-sphincter dyssynergia","volume":"159","author":"Kim","year":"1998","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0015","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/sc.1990.18","article-title":"Pharmacotherapy for urinary bladder dysfunction in spinal cord injury patients","volume":"28","author":"Wyndaele","year":"1990","journal-title":"Spinal Cord"},{"key":"10.1016\/j.urology.2020.03.007_bib0016","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/S0022-5347(17)58796-0","article-title":"External sphincterotomy: its effect on erections","volume":"116","author":"Crane","year":"1976","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0017","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0022-5347(17)67039-3","article-title":"Transurethral sphincterotomy: relationship of site of incision to postoperative potency and delayed hemorrhage","volume":"114","author":"Kiviat","year":"1975","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0018","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/nau.1930140109","article-title":"Non-operative management of the urinary tract in spinal cord injury","volume":"14","author":"Dmochowski","year":"1995","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2020.03.007_bib0019","first-page":"161","article-title":"Compliance and complications of clean intermittent catheterization in the spinal cord injured patient","volume":"33","author":"Chai","year":"1995","journal-title":"Paraplegia"},{"key":"10.1016\/j.urology.2020.03.007_bib0020","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1038\/sj.sc.3101348","article-title":"Complications of intermittent catheterization: their prevention and treatment","volume":"40","author":"Wyndaele","year":"2002","journal-title":"Spinal Cord"},{"key":"10.1016\/j.urology.2020.03.007_bib0021","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.eururo.2008.09.009","article-title":"Recommendations on the use of botulinum toxin in the treatment of lower urinary tract disorders and pelvic floor dysfunctions: a European consensus report","volume":"55","author":"Apostolidis","year":"2009","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0022","first-page":"5787","article-title":"Injection of botulinum toxin type A in the urethral sphincter to treat lower urinary tract dysfunction: review of indications, techniques and results: 2011 update","volume":"18","author":"Mahfouz","year":"2011","journal-title":"Can J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0023","doi-asserted-by":"crossref","first-page":"b2700","DOI":"10.1136\/bmj.b2700","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration","volume":"339","author":"Liberati","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.urology.2020.03.007_bib0024","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1046\/j.1445-2197.2003.02748.x","article-title":"Methodological index for non-randomized studies (minors):development and validation of a new instrument","volume":"76","author":"Slim","year":"2003","journal-title":"ANZ J Surg"},{"key":"10.1016\/j.urology.2020.03.007_bib0025","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.apmr.2008.10.023","article-title":"Transperineal injection of botulinum toxin A for treatment of detrusor sphincter dyssynergia: localization with combined fluoroscopic and electromyographic guidance","volume":"90","author":"Tsai","year":"2009","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.urology.2020.03.007_bib0026","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1002\/nau.20606","article-title":"Satisfaction with urethral injection of botulinum toxin A for detrusor sphincter dyssynergia in patients with spinal cord lesion","volume":"27","author":"Kuo","year":"2008","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2020.03.007_bib0027","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.apmr.2014.10.003","article-title":"Treatment of detrusor external sphincter dyssynergia using ultrasound-guided trocar catheter transurethral botulinum toxin a injection in men with spinal cord injury","volume":"96","author":"Yang","year":"2015","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.urology.2020.03.007_bib0028","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1136\/jnnp.2004.045765","article-title":"Placebo controlled, randomised, double blind study of the effects of botulinum A toxin on detrusor sphincter dyssynergia in multiple sclerosis patients","volume":"76","author":"Gallien","year":"2005","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.urology.2020.03.007_bib0029","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/sj.sc.3100517","article-title":"Botulinum A toxin treatment for detrusor-sphincter dyssynergia in spinal cord disease","volume":"36","author":"Petit","year":"1998","journal-title":"Spinal Cord"},{"key":"10.1016\/j.urology.2020.03.007_bib0030","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S0302-2838(02)00209-9","article-title":"Botulinum a toxin and detrusor sphincter dyssynergia: a double-blind lidocaine-controlled study in 13 patients with spinal cord disease","volume":"42","author":"de S\u00e8ze","year":"2002","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0031","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1111\/ijcp.12152","article-title":"Therapeutic outcome and quality of life between urethral and detrusor botulinum toxin treatment for patients with spinal cord lesions and detrusor sphincter dyssynergia","volume":"67","author":"Kuo","year":"2013","journal-title":"Int J Clin Pract"},{"key":"10.1016\/j.urology.2020.03.007_bib0032","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0022-5347(01)66376-6","article-title":"Botulinum-A toxin as a treatment of detrusor-sphincter dyssynergia: a prospective study in 24 spinal cord injury patients","volume":"155","author":"Schurch","year":"1996","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0033","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1177\/201010581302200202","article-title":"The successful and novel treatment of non-neurogenic detrusor-external sphincter dyssynergia (DESD) with botulinum toxin A","volume":"22","author":"Kuo","year":"2013","journal-title":"Proc Singap Healthc"},{"key":"10.1016\/j.urology.2020.03.007_bib0034","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/S0022-5347(05)67283-7","article-title":"Botulinum-A toxin for treating detrusor hyperreflexia in spinal cord injured patients: a new alternative to anticholinergic drugs? Preliminary results","volume":"164","author":"Schurch","year":"2000","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0035","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.apmr.2009.11.006","article-title":"Transrectal ultrasound-guided transperineal botulinum toxin a injection to the external urethral sphincter for treatment of detrusor external sphincter dyssynergia in patients with spinal cord injury","volume":"91","author":"Chen","year":"2010","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.urology.2020.03.007_bib0036","doi-asserted-by":"crossref","first-page":"744","DOI":"10.2340\/16501977-0255","article-title":"Effect of single botulinum toxin A injection to the external urethral sphincter for treating detrusor external sphincter dyssynergia in spinal cord injury","volume":"40","author":"Chen","year":"2008","journal-title":"J Rehabil Med"},{"key":"10.1016\/j.urology.2020.03.007_bib0037","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0094-0143(05)70309-8","article-title":"Leak-point pressures","volume":"23","author":"McGuire","year":"1996","journal-title":"Urol Clin North Am"},{"key":"10.1016\/j.urology.2020.03.007_bib0038","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1742-1241.2006.01181.x","article-title":"Botulinum toxin injection therapy in the management of lower urinary tract dysfunction","author":"Patel","year":"2006","journal-title":"Int J Clin Pract Suppl"},{"key":"10.1016\/j.urology.2020.03.007_bib0039","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/S0090-4295(02)02541-4","article-title":"Effect of botulinum a toxin in the treatment of voiding dysfunction due to detrusor underactivity","volume":"61","author":"Kuo","year":"2003","journal-title":"Urology"},{"key":"10.1016\/j.urology.2020.03.007_bib0040","doi-asserted-by":"crossref","first-page":"234","DOI":"10.21037\/tau.2016.12.05","article-title":"Use of botulinum toxin for voiding dysfunction","volume":"6","author":"Eldred-Evans","year":"2017","journal-title":"Transl Androl Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0041","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3390\/toxins8040088","article-title":"Use of botulinum toxin A in the treatment of lower urinary tract disorders: A review of the literature","volume":"8","author":"Moore","year":"2016","journal-title":"Toxins (Basel)"},{"key":"10.1016\/j.urology.2020.03.007_bib0042","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.eururo.2007.08.039","article-title":"Botulinum toxin A detrusor injections in patients with neurogenic detrusor overactivity significantly decrease the incidence of symptomatic urinary tract infections","volume":"53","author":"Gam\u00e9","year":"2008","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2020.03.007_bib0043","first-page":"89","article-title":"Botulinun A toxin urethral sphincter injection for neurogenic or nonneurogenic voiding dysfunction","volume":"28","author":"Kuo","year":"2016","journal-title":"Ci Ji Yi Xue Za Zhi"},{"key":"10.1016\/j.urology.2020.03.007_bib0044","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.apmr.2011.11.020","article-title":"A meta-analysis of botulinum toxin sphincteric injections in the treatment of incomplete voiding after spinal cord injury","volume":"93","author":"Mehta","year":"2012","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.urology.2020.03.007_bib0045","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/sc.2015.224","article-title":"Predictors of outcome for urethral injection of botulinum toxin to treat detrusor sphincter dyssynergia in men with spinal cord injury","volume":"54","author":"Soler","year":"2016","journal-title":"Spinal Cord"},{"key":"10.1016\/j.urology.2020.03.007_bib0046","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.urology.2008.04.026","article-title":"Therapeutic satisfaction and dissatisfaction in patients with spinal cord lesions and detrusor sphincter dyssynergia who received detrusor botulinum toxin a injection","volume":"72","author":"Kuo","year":"2008","journal-title":"Urology"},{"key":"10.1016\/j.urology.2020.03.007_bib0047","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1111\/j.1464-410X.2009.08600.x","article-title":"Long-term effects of repeated intradetrusor botulinum neurotoxin A injections on detrusor function in patients with neurogenic bladder dysfunction","volume":"104","author":"Pannek","year":"2009","journal-title":"BJU Int"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429520302739?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429520302739?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T02:06:20Z","timestamp":1758765980000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429520302739"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":47,"alternative-id":["S0090429520302739"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2020.03.007","relation":{},"ISSN":["0090-4295"],"issn-type":[{"value":"0090-4295","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Use of Botulinum Toxin A (BoNT-A) in Detrusor External Sphincter Dyssynergia (DESD): A Systematic Review and Meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urology.2020.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}