{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:12:21Z","timestamp":1793146341282,"version":"4.5.0"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","goldjournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.urology.2025.05.012","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T22:58:07Z","timestamp":1747177087000},"page":"77-83","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Detection of High-grade Bladder Cancer in Urine Samples Using In Situ Hybridization of Long Noncoding RNA UCA1"],"prefix":"10.1016","volume":"201","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3089-5274","authenticated-orcid":false,"given":"Michelle I.","family":"Higgins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangfeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waqar","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changxue","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kengo","family":"Horie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph G.","family":"Cheaib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadra","family":"Sepehri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"VandenBussche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Kates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2025.05.012_bib1","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.eururo.2016.05.041","article-title":"EAU guidelines on non\u2013muscle-invasive urothelial carcinoma of the bladder: update 2016","volume":"71","author":"Babjuk","year":"2017","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2025.05.012_bib2","first-page":"27.e1","article-title":"Is the performance of urinary cytology as high as reported historically? A contemporary analysis in the detection and surveillance of bladder cancer","volume":"32","author":"Yafi","year":"2014","journal-title":"Urol Oncol Semin Orig Investig"},{"key":"10.1016\/j.urology.2025.05.012_bib3","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1038\/modpathol.2008.193","article-title":"Diagnosis of urothelial carcinoma from urine","volume":"22","author":"T\u00eatu","year":"2009","journal-title":"Mod Pathol"},{"key":"10.1016\/j.urology.2025.05.012_bib4","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ucl.2013.01.015","article-title":"Urinary markers\/cytology","volume":"40","author":"Tomasini","year":"2013","journal-title":"Urol Clin N Am"},{"key":"10.1016\/j.urology.2025.05.012_bib5","doi-asserted-by":"crossref","first-page":"14374","DOI":"10.3390\/ijms241814374","article-title":"Molecular markers for bladder cancer screening: an insight into bladder cancer and FDA-approved biomarkers","volume":"24","author":"Flores Monar","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.urology.2025.05.012_bib6","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/cyt.12345","article-title":"A review of the Paris system for reporting urinary cytology","volume":"27","author":"VandenBussche","year":"2016","journal-title":"Cytopathology"},{"key":"10.1016\/j.urology.2025.05.012_bib7","doi-asserted-by":"crossref","first-page":"922","DOI":"10.7326\/M15-0997","article-title":"Urinary biomarkers for diagnosis of bladder cancer: a systematic review and meta-analysis","volume":"163","author":"Chou","year":"2015","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.urology.2025.05.012_bib8","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.juro.2016.06.049","article-title":"Diagnosis and treatment of non-muscle invasive bladder cancer: AUA\/SUO guideline","volume":"196","author":"Cheng","year":"2016","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2025.05.012_bib9","article-title":"lncRNA-UCA1 in the diagnosis of bladder cancer: a meta-analysis","volume":"100","author":"Ding","year":"2021","journal-title":"Medicine"},{"key":"10.1016\/j.urology.2025.05.012_bib10","doi-asserted-by":"crossref","unstructured":"Lebrun L., Milowich D., Le Mercier M., et al. UCA1 overexpression is associated with less aggressive subtypes of bladder cancer. Oncol Rep. Published online September 10, 2018. doi:10.3892\/or.2018.6697.","DOI":"10.3892\/or.2018.6697"},{"key":"10.1016\/j.urology.2025.05.012_bib11","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1016\/j.febslet.2008.05.012","article-title":"UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion","volume":"582","author":"Wang","year":"2008","journal-title":"FEBS Lett"},{"key":"10.1016\/j.urology.2025.05.012_bib12","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.cell.2017.09.007","article-title":"Comprehensive molecular characterization of muscle-invasive bladder cancer","volume":"171","author":"Robertson","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.urology.2025.05.012_bib13","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1159\/000499027","article-title":"A review of urine ancillary tests in the era of the Paris system","volume":"64","author":"Allison","year":"2020","journal-title":"Acta Cytol"},{"key":"10.1016\/j.urology.2025.05.012_bib14","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/s41391-020-00272-6","article-title":"A novel method for detection of exfoliated prostate cancer cells in urine by RNA in situ hybridization","volume":"24","author":"Eskra","year":"2021","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"10.1016\/j.urology.2025.05.012_bib15","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1097\/JU.0000000000003639","article-title":"International bladder cancer group intermediate-risk nonmuscle-invasive bladder cancer scoring system predicts outcomes of patients on active surveillance","volume":"210","author":"Tan","year":"2023","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2025.05.012_bib16","first-page":"66.e25","article-title":"Prospective analysis of sensitivity and specificity of urinary cytology and other urinary biomarkers for bladder cancer","volume":"33","author":"Yafi","year":"2015","journal-title":"Urol Oncol Semin Orig Investig"},{"key":"10.1016\/j.urology.2025.05.012_bib17","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1097\/JU.0000000000003846","article-title":"Diagnosis and treatment of non-muscle invasive bladder cancer: AUA\/SUO guideline: 2024 Amendment","volume":"211","author":"Holzbeierlein","year":"2024","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2025.05.012_bib18","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.eururo.2011.05.053","article-title":"Urine markers for detection and surveillance of non\u2013muscle-invasive bladder cancer","volume":"60","author":"Tilki","year":"2011","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2025.05.012_bib19","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/1476-4598-12-101","article-title":"The complexity of bladder cancer: long noncoding RNAs are on the stage","volume":"12","author":"Zhang","year":"2013","journal-title":"Mol Cancer"},{"key":"10.1016\/j.urology.2025.05.012_bib20","doi-asserted-by":"crossref","first-page":"4851","DOI":"10.1158\/1078-0432.CCR-06-0134","article-title":"Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma","volume":"12","author":"Wang","year":"2006","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.urology.2025.05.012_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0176287","article-title":"Diagnostic and prognostic value of long noncoding RNAs as biomarkers in urothelial carcinoma","volume":"12","author":"Droop","year":"2017","journal-title":"PLoS One"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429525004686?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429525004686?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T08:07:41Z","timestamp":1750493261000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429525004686"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":21,"alternative-id":["S0090429525004686"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2025.05.012","relation":{},"ISSN":["0090-4295"],"issn-type":[{"value":"0090-4295","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Detection of High-grade Bladder Cancer in Urine Samples Using In Situ Hybridization of Long Noncoding RNA UCA1","name":"articletitle","label":"Article Title"},{"value":"Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urology.2025.05.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}