{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T06:01:31Z","timestamp":1780725691597,"version":"3.54.1"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T00:00:00Z","timestamp":1754611200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004622","name":"KWF Kankerbestrijding","doi-asserted-by":"publisher","award":["15754"],"award-info":[{"award-number":["15754"]}],"id":[{"id":"10.13039\/501100004622","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","goldjournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.urology.2025.08.006","type":"journal-article","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T15:10:17Z","timestamp":1754579417000},"page":"166-171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Antibiotic Prophylaxis Is Not Required Before MRI-Guided Transperineal Prostate Biopsy"],"prefix":"10.1016","volume":"207","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5780-6625","authenticated-orcid":false,"given":"S.F.","family":"Westerhout","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.P.","family":"Rynja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.P.Z.","family":"van Steenbergen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.S.","family":"Mertens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.","family":"Roobol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.J.","family":"van Leeuwen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"Noordzij","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2025.08.006_bib1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.eururo.2024.03.027","article-title":"EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer-2024 Update. Part I: screening, diagnosis, and local treatment with curative intent","volume":"86","author":"Cornford","year":"2024","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2025.08.006_bib2","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S1470-2045(25)00100-7","article-title":"Local anaesthetic transperineal biopsy versus transrectal prostate biopsy in prostate cancer detection (TRANSLATE): a multicentre, randomised, controlled trial","volume":"26","author":"Bryant","year":"2025","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.urology.2025.08.006_bib3","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.eururo.2023.12.015","article-title":"Transperineal versus transrectal magnetic resonance imaging-targeted and systematic prostate biopsy to prevent infectious complications: the PREVENT randomized trial","volume":"86","author":"Hu","year":"2024","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2025.08.006_bib4","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/JU.0000000000003788","article-title":"Complications following transrectal and transperineal prostate biopsy: results of the ProBE-PC randomized clinical trial","volume":"211","author":"Mian","year":"2024","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2025.08.006_bib5","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.euo.2024.01.019","article-title":"Transperineal versus transrectal magnetic resonance imaging-targeted biopsies for prostate cancer diagnosis: final results of the randomized PERFECT trial (CCAFU-PR1)","volume":"7","author":"Ploussard","year":"2024","journal-title":"Eur Urol Oncol"},{"key":"10.1016\/j.urology.2025.08.006_bib6","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/j.euo.2024.07.009","article-title":"Transperineal versus transrectal magnetic resonance imaging-targeted prostate biopsy: a systematic review and meta-analysis of prospective studies","volume":"7","author":"Zattoni","year":"2024","journal-title":"Eur Urol Oncol"},{"key":"10.1016\/j.urology.2025.08.006_bib7","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1097\/JU.0000000000001399","article-title":"Nonantibiotic strategies for the prevention of infectious complications following prostate biopsy: a systematic review and meta-analysis","volume":"205","author":"Pradere","year":"2021","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2025.08.006_bib8","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1017\/S0950268815002885","article-title":"The global burden of major infectious complications following prostate biopsy","volume":"144","author":"Bennett","year":"2016","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.urology.2025.08.006_bib9","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.euros.2022.01.001","article-title":"Role of prophylactic antibiotics in transperineal prostate biopsy: a systematic review and meta-analysis","volume":"37","author":"Basourakos","year":"2022","journal-title":"Eur Urol Open Sci"},{"key":"10.1016\/j.urology.2025.08.006_bib10","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/JU.0000000000002251","article-title":"Infection rate after transperineal prostate biopsy with and without prophylactic antibiotics: results from a systematic review and meta-analysis of comparative studies","volume":"207","author":"Castellani","year":"2022","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2025.08.006_bib11","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/s41391-022-00641-3","article-title":"The transition from transrectal to transperineal prostate biopsy without antibiotic prophylaxis: cancer detection rates and complication rates","volume":"26","author":"Hogenhout","year":"2023","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"10.1016\/j.urology.2025.08.006_bib12","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1016\/S1473-3099(22)00373-5","article-title":"Antibiotic prophylaxis versus no antibiotic prophylaxis in transperineal prostate biopsies (NORAPP): a randomised, open-label, non-inferiority trial","volume":"22","author":"Jacewicz","year":"2022","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.urology.2025.08.006_bib13","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1046\/j.1464-410X.1996.01014.x","article-title":"Infection after transrectal core biopsies of the prostate\u2014risk factors and antibiotic prophylaxis","volume":"77","author":"Aus","year":"1996","journal-title":"Br J Urol"},{"key":"10.1016\/j.urology.2025.08.006_bib14","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.urology.2016.12.011","article-title":"Prostate biopsy-related infection: a systematic review of risk factors, prevention strategies, and management approaches","volume":"104","author":"Roberts","year":"2017","journal-title":"Urology"},{"key":"10.1016\/j.urology.2025.08.006_bib15","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1111\/bju.12368","article-title":"Mortality and complications after prostate biopsy in the Prostate, Lung, Colorectal and Ovarian Cancer Screening (PLCO) trial","volume":"113","author":"Pinsky","year":"2014","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2025.08.006_bib16","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1016\/S0140-6736(24)00651-2","article-title":"The Lancet Commission on prostate cancer: planning for the surge in cases","volume":"403","author":"James","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.urology.2025.08.006_bib17","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0140-6736(21)02724-0","article-title":"Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis","volume":"399","author":"Collaborators","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.urology.2025.08.006_bib18","unstructured":"World Health Organization, Regional Office for Europe. The fight against Antimicrobial Resistance is significant for cancer prevention and treatment. 2020. Accessed February 6, 2025. https:\/\/iris.who.int\/bitstream\/handle\/10665\/337511\/WHO-EURO-2020\u20131628-41379\u201356382-eng.pdf."},{"key":"10.1016\/j.urology.2025.08.006_bib19","unstructured":"Foundation S-TPCR. Rotterdam Prostate Cancer Risk Calculator (RPCRC). Accessed February 6, 2025. https:\/\/www.prostatecancer-riskcalculator.com\/."},{"key":"10.1016\/j.urology.2025.08.006_bib20","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1111\/bju.12132","article-title":"Definitions of terms, processes and a minimum dataset for transperineal prostate biopsies: a standardization approach of the Ginsburg Study Group for Enhanced Prostate Diagnostics","volume":"112","author":"Kuru","year":"2013","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2025.08.006_bib21","doi-asserted-by":"crossref","first-page":"d7894","DOI":"10.1136\/bmj.d7894","article-title":"Short term outcomes of prostate biopsy in men tested for cancer by prostate specific antigen: prospective evaluation within ProtecT study","volume":"344","author":"Rosario","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.urology.2025.08.006_bib22","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.urology.2025.08.006_bib23","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","article-title":"Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey","volume":"240","author":"Dindo","year":"2004","journal-title":"Ann Surg"},{"key":"10.1016\/j.urology.2025.08.006_bib24","article-title":"Infectious complications following transperineal prostate biopsy with or without periprocedural antibiotic prophylaxis-a systematic review including meta-analysis of all comparative studies","author":"Wolff","year":"2024","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"10.1016\/j.urology.2025.08.006_bib25","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/bju.15039","article-title":"Comparison of complications after transrectal and transperineal prostate biopsy: a national population-based study","volume":"126","author":"Berry","year":"2020","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2025.08.006_bib26","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s12957-019-1573-0","article-title":"Transperineal versus transrectal prostate biopsy in the diagnosis of prostate cancer: a systematic review and meta-analysis","volume":"17","author":"Xiang","year":"2019","journal-title":"World J Surg Oncol"},{"key":"10.1016\/j.urology.2025.08.006_bib27","doi-asserted-by":"crossref","first-page":"23322","DOI":"10.18632\/oncotarget.15056","article-title":"Comparison between transrectal and transperineal prostate biopsy for detection of prostate cancer: a meta-analysis and trial sequential analysis","volume":"8","author":"Xue","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.urology.2025.08.006_bib28","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1097\/JU.0000000000003492","article-title":"Early detection of prostate cancer: AUA\/SUO Guideline Part II: considerations for a prostate biopsy","volume":"210","author":"Wei","year":"2023","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2025.08.006_bib29","doi-asserted-by":"crossref","first-page":"E86","DOI":"10.1111\/j.1464-410X.2011.10768.x","article-title":"Cost-effectiveness of standard vs intensive antibiotic regimens for transrectal ultrasonography (TRUS)-guided prostate biopsy prophylaxis","volume":"110","author":"Adibi","year":"2012","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2025.08.006_bib30","unstructured":"CDC. Antibiotic Resistance Threats in the United States, 2019. 2019. Accessed June 30, 2025. https:\/\/www.cdc.gov\/DrugResistance\/Biggest-Threats.html."}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429525007587?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429525007587?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T05:08:14Z","timestamp":1780722494000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429525007587"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":30,"alternative-id":["S0090429525007587"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2025.08.006","relation":{},"ISSN":["0090-4295"],"issn-type":[{"value":"0090-4295","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antibiotic Prophylaxis Is Not Required Before MRI-Guided Transperineal Prostate Biopsy","name":"articletitle","label":"Article Title"},{"value":"Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urology.2025.08.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}