{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T13:57:27Z","timestamp":1781704647350,"version":"3.54.5"},"reference-count":16,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urologic Oncology: Seminars and Original Investigations"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.urolonc.2010.11.011","type":"journal-article","created":{"date-parts":[[2011,8,29]],"date-time":"2011-08-29T04:23:19Z","timestamp":1314591799000},"page":"228-233","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["c-Jun is involved in interstitial cystitis antiproliferative factor (APF)-induced growth inhibition of human bladder cancer T24 cells"],"prefix":"10.1016","volume":"31","author":[{"given":"Zeliang","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuyan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Decai","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenxing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuize","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.urolonc.2010.11.011_bib1","first-page":"334","article-title":"Bladder cancer detection, treatment, and outcomes","volume":"75","author":"Latini","year":"2010","journal-title":"Opportunities and challenges urology"},{"key":"10.1016\/j.urolonc.2010.11.011_bib2","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.1038\/sj.onc.1204383","article-title":"AP-1 in cell proliferation and survival","volume":"20","author":"Shaulian","year":"2001","journal-title":"Oncogene"},{"key":"10.1016\/j.urolonc.2010.11.011_bib3","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1159\/000474508","article-title":"p53 and c-Jun expression in urinary bladder transitional cell carcinoma: Correlation with proliferating cell nuclear antigen (PCNA) histological grade and clinical stage","volume":"31","author":"Skopelitou","year":"1997","journal-title":"Eur Urol"},{"key":"10.1016\/j.urolonc.2010.11.011_bib4","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1111\/j.1464-410X.1994.tb07121.x","article-title":"c-Jun oncogene expression in transitional cell carcinoma of the urinary bladder","volume":"74","author":"Tiniakos","year":"1994","journal-title":"Br J Urol"},{"key":"10.1016\/j.urolonc.2010.11.011_bib5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1471-2490-4-3","article-title":"Interstitial cystitis antiproliferative factor (APF) as a cell-cycle modulator","volume":"4","author":"Rashid","year":"2004","journal-title":"BMC Urol"},{"key":"10.1016\/j.urolonc.2010.11.011_bib6","doi-asserted-by":"crossref","first-page":"11803","DOI":"10.1073\/pnas.0404509101","article-title":"An antiproliferative factor from interstitial cystitis patients is a frizzled 8 protein-related sialoglycopeptide","volume":"101","author":"Keay","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.urolonc.2010.11.011_bib7","doi-asserted-by":"crossref","first-page":"37836","DOI":"10.1074\/jbc.M604581200","article-title":"CKAP4\/p63 is a receptor for the frizzled-8 protein-related antiproliferative factor from interstitial cystitis patients","volume":"281","author":"Conrads","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1016\/j.urolonc.2010.11.011_bib8","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/S0090-4295(03)00005-0","article-title":"Decreased in vitro proliferation of bladder epithelial cells from patients with interstitial cystitis","volume":"61","author":"Keay","year":"2003","journal-title":"Urology"},{"key":"10.1016\/j.urolonc.2010.11.011_bib9","doi-asserted-by":"crossref","first-page":"3795","DOI":"10.1016\/j.febslet.2007.06.058","article-title":"p53 mediates interstitial cystitis antiproliferative factor (APF)-induced growth inhibition of human urothelial cells","volume":"581","author":"Kim","year":"2007","journal-title":"FEBS Lett"},{"key":"10.1016\/j.urolonc.2010.11.011_bib10","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1152\/physiolgenomics.00055.2003","article-title":"Changes in human bladder epithelial cell gene expression associated with interstitial cystitis or antiproliferative factor treatment","volume":"14","author":"Keay","year":"2003","journal-title":"Physiol Genomics"},{"key":"10.1016\/j.urolonc.2010.11.011_bib11","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0092-8674(03)00042-4","article-title":"Liver Tumor Development: c-Jun antagonizes the proapoptotic activity of p53","volume":"112","author":"Eferl","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.urolonc.2010.11.011_bib12","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1101\/gad.390506","article-title":"c-Jun\/AP-1 controls liver regeneration by repressing p53\/p21 and p38 MAPK activity","volume":"20","author":"Stepniak","year":"2006","journal-title":"Genes Dev"},{"key":"10.1016\/j.urolonc.2010.11.011_bib13","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1101\/gad.13.5.607","article-title":"Control of cell cycle progression by c-Jun is p53-dependent","volume":"13","author":"Schreiber","year":"1999","journal-title":"Genes Dev"},{"key":"10.1016\/j.urolonc.2010.11.011_bib14","first-page":"991","article-title":"Molecular cloning and characterization of human frizzled-8 gene on chromosome 10p11.2","volume":"18","author":"Saitoh","year":"2001","journal-title":"Int J Oncol"},{"key":"10.1016\/j.urolonc.2010.11.011_bib15","unstructured":"Keay S, Tocci G, Zhang CO, et al. The Frizzled 8-related antiproliferative factor from IC patients inhibits bladder and kidney carcinoma cell proliferation in vitro. 18th EORTCNCI-AACR Symposium. Molecular targets and cancer therapeutics. November 7\u201310, 2006; Prague, Czech Republic."},{"key":"10.1016\/j.urolonc.2010.11.011_bib16","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1464-410X.2008.08097.x","article-title":"Heparin-binding epidermal growth factor-like growth factor functionally antagonizes interstitial cystitis antiproliferative factor via mitogen-activated protein kinase pathway activation","volume":"103","author":"Kim","year":"2009","journal-title":"BJU Int"}],"container-title":["Urologic Oncology: Seminars and Original Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078143910003649?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078143910003649?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T09:58:29Z","timestamp":1761040709000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1078143910003649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S1078143910003649"],"URL":"https:\/\/doi.org\/10.1016\/j.urolonc.2010.11.011","relation":{},"ISSN":["1078-1439"],"issn-type":[{"value":"1078-1439","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"c-Jun is involved in interstitial cystitis antiproliferative factor (APF)-induced growth inhibition of human bladder cancer T24 cells","name":"articletitle","label":"Article Title"},{"value":"Urologic Oncology: Seminars and Original Investigations","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urolonc.2010.11.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}