{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:23:52Z","timestamp":1791829432262,"version":"4.3.4"},"reference-count":20,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urologic Oncology: Seminars and Original Investigations"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.urolonc.2021.06.019","type":"journal-article","created":{"date-parts":[[2021,7,20]],"date-time":"2021-07-20T22:50:31Z","timestamp":1626821431000},"page":"791.e1-791.e7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Identification of oncological characteristics associated with improved overall survival in patients with adrenocortical carcinoma treated with adjuvant radiation therapy: Insights from the National Cancer Database"],"prefix":"10.1016","volume":"39","author":[{"given":"Kevin B.","family":"Ginsburg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akhil A.","family":"Chandra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared P.","family":"Schober","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Handorf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert G.","family":"Uzzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard E.","family":"Greenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David YT","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalia","family":"Viterbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc C.","family":"Smaldone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Kutikov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Hallman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres F.","family":"Correa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.urolonc.2021.06.019_bib0001","series-title":"Cancer, Adrenal","author":"Torti","year":"2020"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0002","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1530\/EJE-13-0519","article-title":"Adrenocortical carcinoma: clinical outcomes and prognosis of 330 patients at a tertiary care center","volume":"169","author":"Ayala-Ramirez","year":"2013","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0003","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.ijrobp.2015.01.007","article-title":"Adjuvant radiation therapy improves local control after surgical resection in patients with localized adrenocortical carcinoma","volume":"92","author":"Sabolch","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0004","doi-asserted-by":"crossref","first-page":"693","DOI":"10.6004\/jnccn.2018.0056","article-title":"NCCN Guidelines Insights: Neuroendocrine and Adrenal Tumors, Version 2.2018","volume":"16","author":"Shah","year":"2018","journal-title":"J Natl Compr Canc Netw"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0005","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1245\/s10434-018-6398-5","article-title":"Impact of micro- and macroscopically positive surgical margins on survival after resection of adrenocortical carcinoma","volume":"25","author":"Anderson","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0006","unstructured":"American Cancer Society. Survival rates for adrenal cancer. 2018."},{"key":"10.1016\/j.urolonc.2021.06.019_bib0007","doi-asserted-by":"crossref","first-page":"e316","DOI":"10.3747\/co.24.3533","article-title":"Adrenocortical carcinoma: patterns of care and role of adjuvant radiation therapy-a population-based study and review of the literature","volume":"24","author":"Atallah","year":"2017","journal-title":"Curr Oncol"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0008","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.1245\/s10434-018-6510-x","article-title":"Adjuvant radiation is associated with improved survival for select patients with non-metastatic adrenocortical carcinoma","volume":"25","author":"Nelson","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0009","doi-asserted-by":"crossref","DOI":"10.3390\/cancers12020508","article-title":"Adjuvant therapy in adrenocortical carcinoma: reflections and future directions","volume":"12","author":"Bedrose","year":"2020","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0010","doi-asserted-by":"crossref","unstructured":"Martin Fassnacht OMD, Tobias Else, Eric Baudin, Alfredo Berruti, Ronald R. de Krijger. European Society of Endocrinology clinical practice guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors. Eur J Endocrinol 2018;179:G1-G46.","DOI":"10.1530\/EJE-18-0608"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0011","doi-asserted-by":"crossref","first-page":"3566","DOI":"10.1210\/jc.2018-00918","article-title":"Predictors of survival in adrenocortical carcinoma: an analysis from the National Cancer Database","volume":"103","author":"Tella","year":"2018","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0012","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1002\/jso.23568","article-title":"Comparing national cancer registries: The National Cancer Data Base (NCDB) and the surveillance, epidemiology, and end results (SEER) program","volume":"109","author":"Mohanty","year":"2014","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0013","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1245\/s10434-007-9747-3","article-title":"The National Cancer Data Base: a powerful initiative to improve cancer care in the United States","volume":"15","author":"Bilimoria","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0014","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1001\/jamaoncol.2016.6905","article-title":"Using the National Cancer Database for outcomes research: a review","volume":"3","author":"Boffa","year":"2017","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0015","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1001\/jamasurg.2018.0492","article-title":"Practical guide to surgical data sets: National Cancer Database (NCDB)","volume":"153","author":"Merkow","year":"2018","journal-title":"JAMA Surg"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0016","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1245\/s10434-015-4803-x","article-title":"Adrenocortical carcinoma: impact of surgical margin status on long-term outcomes","volume":"23","author":"Margonis","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0017","doi-asserted-by":"crossref","first-page":"4501","DOI":"10.1210\/jc.2006-1007","article-title":"Efficacy of adjuvant radiotherapy of the tumor bed on local recurrence of adrenocortical carcinoma","volume":"91","author":"Fassnacht","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0018","doi-asserted-by":"crossref","first-page":"3743","DOI":"10.1210\/jc.2019-00029","article-title":"Adjuvant radiation improves recurrence-free survival and overall survival in adrenocortical carcinoma","volume":"104","author":"Gharzai","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0019","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.4103\/jcrt.JCRT_996_15","article-title":"Adjuvant radiotherapy after surgical resection for adrenocortical carcinoma: a systematic review of observational studies and meta-analysis","volume":"15","author":"Viani","year":"2019","journal-title":"J Cancer Res Ther"},{"key":"10.1016\/j.urolonc.2021.06.019_bib0020","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1210\/jc.2014-3182","article-title":"Major prognostic role of Ki67 in localized adrenocortical carcinoma after complete resection","volume":"100","author":"Beuschlein","year":"2015","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Urologic Oncology: Seminars and Original Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078143921002787?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078143921002787?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T10:22:47Z","timestamp":1761042167000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1078143921002787"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":20,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S1078143921002787"],"URL":"https:\/\/doi.org\/10.1016\/j.urolonc.2021.06.019","relation":{},"ISSN":["1078-1439"],"issn-type":[{"value":"1078-1439","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of oncological characteristics associated with improved overall survival in patients with adrenocortical carcinoma treated with adjuvant radiation therapy: Insights from the National Cancer Database","name":"articletitle","label":"Article Title"},{"value":"Urologic Oncology: Seminars and Original Investigations","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urolonc.2021.06.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}