{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T03:58:59Z","timestamp":1774583939718,"version":"3.50.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urologic Oncology: Seminars and Original Investigations"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.urolonc.2022.03.007","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T00:44:40Z","timestamp":1650588280000},"page":"276.e1-276.e9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Characterization of tumor thrombus in renal cell carcinoma with prostate specific membrane antigen (PSMA) positron emission tomography (PET)\/computed tomography (CT)"],"prefix":"10.1016","volume":"40","author":[{"given":"Arsalan","family":"Tariq","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"McGeorge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Pearce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Handoo","family":"Rhee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Wood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Kyle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Marsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheliyan","family":"Raveenthiran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rhiannon","family":"McBean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jurjen","family":"Westera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nigel","family":"Dunglison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Esler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anojan","family":"Navaratnam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Yaxley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Pattison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0552-7402","authenticated-orcid":false,"given":"Matthew J.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.urolonc.2022.03.007_bib0001","first-page":"247","article-title":"Renal Cell Carcinoma with IVC Thrombi; Current Concepts and Future Perspectives","volume":"2","author":"Nouh","year":"2008","journal-title":"Clin Med Oncol"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0002","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S0090-4295(99)00136-3","article-title":"Renal cell carcinoma with an infrarenal vena caval tumor thrombus","volume":"54","author":"Mootha","year":"1999","journal-title":"Urology"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0003","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1016\/S0003-4975(97)00329-9","article-title":"Surgical management of renal cell carcinoma with inferior vena cava tumor thrombus","volume":"63","author":"Nesbitt","year":"1997","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0004","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.urology.2018.02.019","article-title":"The Adverse Survival Implications of Bland Thrombus in Renal Cell Carcinoma With Venous Tumor Thrombus","volume":"115","author":"Hutchinson","year":"2018","journal-title":"Urology"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0005","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s11934-020-01007-9","article-title":"Surgical Tips for Inferior Vena Cava Thrombectomy","volume":"21","author":"Ghoreifi","year":"2020","journal-title":"Curr Urol Rep"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0006","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/j.urolonc.2011.12.006","article-title":"Natural history of untreated renal cell carcinoma with venous tumor thrombus","volume":"31","author":"Reese","year":"2013","journal-title":"Urol Oncol"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0007","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.eururo.2009.06.009","article-title":"Long-term survival in patients undergoing radical nephrectomy and inferior vena cava thrombectomy: single-center experience","volume":"57","author":"Ciancio","year":"2010","journal-title":"Eur Urol"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0008","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1007\/s11934-014-0404-7","article-title":"Lessons learned from the International Renal Cell Carcinoma-Venous Thrombus Consortium (IRCC-VTC)","volume":"15","author":"Martinez-Salamanca","year":"2014","journal-title":"Curr Urol Rep"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0009","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.eururo.2010.10.001","article-title":"Prognostic impact of the 2009 UICC\/AJCC TNM staging system for renal cell carcinoma with venous extension","volume":"59","author":"Mart\u00ednez-Salamanca","year":"2011","journal-title":"Eur Urol"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0010","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1097\/01.rct.0000146113.56194.6d","article-title":"Preoperative staging of renal cell carcinoma with inferior vena cava thrombus using multidetector CT and MRI: prospective study with histopathological correlation","volume":"29","author":"Hallscheidt","year":"2005","journal-title":"J Comput Assist Tomogr"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0011","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.clgc.2013.07.006","article-title":"Tumor necrosis on magnetic resonance imaging correlates with aggressive histology and disease progression in clear cell renal cell carcinoma","volume":"12","author":"Beddy","year":"2014","journal-title":"Clin Genitourin Cancer"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0012","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1177\/2051415818773664","article-title":"Generation of a urachal cyst and abscess secondary to high pressure chronic urinary retention","volume":"12","author":"Akman","year":"2019","journal-title":"Journal of Clinical Urology"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0013","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/s00345-007-0191-6","article-title":"Evaluation of tumor thrombi in the inferior vena cava with intraoperative ultrasound","volume":"25","author":"Trombetta","year":"2007","journal-title":"World J Urol"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0014","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s40644-018-0150-z","article-title":"Renal cell carcinoma with venous extension: prediction of inferior vena cava wall invasion by MRI","volume":"18","author":"Adams","year":"2018","journal-title":"Cancer Imaging"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0015","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s13550-016-0231-6","article-title":"Pilot study: use of gallium-68 PSMA PET for detection of metastatic lesions in patients with renal tumour","volume":"6","author":"Rhee","year":"2016","journal-title":"EJNMMI Res"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0016","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1007\/s00259-019-04432-2","article-title":"The use of (68)Ga-PET\/CT PSMA in the staging of primary and suspected recurrent renal cell carcinoma","volume":"46","author":"Raveenthiran","year":"2019","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0017","first-page":"4","article-title":"Imaging tumour thrombus of clear cell renal cell carcinoma: FDG PET or PSMA PET? Direct in vivo comparison of two technologies","volume":"16","author":"Saadat","year":"2018","journal-title":"Urol Case Rep"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0018","doi-asserted-by":"crossref","first-page":"S147","DOI":"10.21037\/tau.2019.04.10","article-title":"Prostate specific membrane antigen (PSMA) expression in vena cava tumour thrombi of clear cell renal cell carcinoma suggests a role for PSMA-driven tumour neoangiogenesis","volume":"8","author":"Morgantetti","year":"2019","journal-title":"Transl Androl Urol"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0019","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1464-410X.2004.04897.x","article-title":"The Mayo Clinic experience with surgical management, complications and outcome for patients with renal cell carcinoma and venous tumour thrombus","volume":"94","author":"Blute","year":"2004","journal-title":"BJU Int"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0020","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1111\/j.1464-410X.1987.tb04832.x","article-title":"Surgical treatment of renal cancer with vena cava extension","volume":"59","author":"Neves","year":"1987","journal-title":"Br J Urol"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0021","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.urology.2007.03.025","article-title":"Expression of prostate-specific membrane antigen in tumor-associated neovasculature of renal neoplasms","volume":"70","author":"Baccala","year":"2007","journal-title":"Urology"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0022","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1148\/radiol.09090304","article-title":"Differentiation of malignant thrombus from bland thrombus of the portal vein in patients with hepatocellular carcinoma: application of diffusion-weighted MR imaging","volume":"254","author":"Catalano","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0023","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1186\/1471-2407-14-590","article-title":"Differentiation of bland from neoplastic thrombus of the portal vein in patients with hepatocellular carcinoma: application of susceptibility-weighted MR imaging","volume":"14","author":"Li","year":"2014","journal-title":"BMC Cancer"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0024","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1159\/000505191","article-title":"How to Best Detect Portal Vein Tumor Thrombosis in Patients with Hepatocellular Carcinoma Meeting the Milan Criteria: Gadoxetic Acid-Enhanced MRI versus Contrast-Enhanced CT","volume":"9","author":"Bae","year":"2020","journal-title":"Liver Cancer"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0025","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1148\/rg.283075101","article-title":"Imaging the Inferior Vena Cava: A Road Less Traveled","volume":"28","author":"Kandpal","year":"2008","journal-title":"RadioGraphics"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0026","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1097\/RLU.0000000000003664","article-title":"Utility of 18F\u2013Prostate-Specific Membrane Antigen 1007 in Imaging of Tumor Thrombus of Renal Cell Carcinoma","volume":"46","author":"Zeng","year":"2021","journal-title":"Clinical Nuclear Medicine"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0027","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1007\/s11307-018-01307-0","article-title":"A Review of Prostate-Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET) in Renal Cell Carcinoma (RCC)","volume":"21","author":"Ahn","year":"2019","journal-title":"Mol Imaging Biol"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0028","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1097\/01.cej.0000220641.46470.77","article-title":"Detection of tumour thrombus by 18F-FDG-PET\/CT imaging","volume":"16","author":"Lai","year":"2007","journal-title":"Eur J Cancer Prev"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0038","doi-asserted-by":"crossref","unstructured":"Tariq A, Kwok M, Pearce A, Rhee H, Kyle S, Marsh P et al. The role of dual tracer PSMA and FDG PET\/CT in renal cell carcinoma (RCC) compared to conventional imaging: A multi-institutional case series with intra-individual comparison. Urol Oncol. 2022;40(2):66.e1\u201366.e9.","DOI":"10.1016\/j.urolonc.2021.11.006"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0029","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1177\/03915603211007030","article-title":"Perioperative and oncological outcomes of renal cell carcinoma with venous tumour thrombus","volume":"89","author":"Bokka","year":"2022","journal-title":"Urologia"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0030","doi-asserted-by":"crossref","first-page":"e13811","DOI":"10.1111\/ijcp.13811","article-title":"Clinical outcomes of radical surgery in patients with renal carcinoma and associated venous thrombosis: Single-centre experience in a tertiary care institution","volume":"75","author":"Onal","year":"2021","journal-title":"Int J Clin Pract"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0039","unstructured":"Tariq A, McCart Reed AE, Morton A, Porten S, Vela I, Williams ED et al. Urothelial Carcinoma and Prostate-specific Membrane Antigen: Cellular, Imaging, and Prognostic Implications.Eur Urol Focus. (in press)"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0031","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/S0140-6736(20)30314-7","article-title":"Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multicentre study","volume":"395","author":"Hofman","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0032","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.2967\/jnumed.120.257915","article-title":"68)Ga-PSMA-11 PET\/CT Improves Tumor Detection and Impacts Management in Patients with Hepatocellular Carcinoma","volume":"62","author":"Hirmas","year":"2021","journal-title":"J Nucl Med"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0033","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s00259-020-04944-2","article-title":"(68) Ga-PSMA PET\/CT tumour intensity pre-operatively predicts adverse pathological outcomes and progression-free survival in localised prostate cancer","volume":"48","author":"Roberts","year":"2021","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0034","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1007\/s13139-013-0245-1","article-title":"Can Initial (18) F-FDG PET-CT Imaging Give Information on Metastasis in Patients with Primary Renal Cell Carcinoma?","volume":"48","author":"Lee","year":"2014","journal-title":"Nucl Med Mol Imaging"},{"key":"10.1016\/j.urolonc.2022.03.007_bib0035","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s00259-020-04916-6","article-title":"Comprehensive evaluation of 68Ga-PSMA-11 PET\/CT parameters for discriminating pathological characteristics in primary clear-cell renal cell carcinoma","volume":"48","author":"Gao","year":"2021","journal-title":"European Journal of Nuclear Medicine and Molecular Imaging"}],"container-title":["Urologic Oncology: Seminars and Original Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078143922000795?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078143922000795?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T10:25:47Z","timestamp":1761042347000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1078143922000795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["S1078143922000795"],"URL":"https:\/\/doi.org\/10.1016\/j.urolonc.2022.03.007","relation":{},"ISSN":["1078-1439"],"issn-type":[{"value":"1078-1439","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of tumor thrombus in renal cell carcinoma with prostate specific membrane antigen (PSMA) positron emission tomography (PET)\/computed tomography (CT)","name":"articletitle","label":"Article Title"},{"value":"Urologic Oncology: Seminars and Original Investigations","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urolonc.2022.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}