{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:12:42Z","timestamp":1761045162829,"version":"build-2065373602"},"reference-count":33,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urologic Oncology: Seminars and Original Investigations"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.urolonc.2023.10.008","type":"journal-article","created":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T07:08:05Z","timestamp":1699945685000},"page":"476-482","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["A systematic review of pN0 testicular seminoma: a new clinical entity and future directions"],"prefix":"10.1016","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0362-9109","authenticated-orcid":false,"given":"Ala'a","family":"Farkouh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanha","family":"Shete","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai Wen","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew I.","family":"Buell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.urolonc.2023.10.008_bib0001","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s00345-021-03854-8","article-title":"Clinical stage II seminoma: management options","volume":"40","author":"Alsyouf","year":"2022","journal-title":"World J Urol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0002","doi-asserted-by":"crossref","first-page":"3009","DOI":"10.1200\/JCO.22.00624","article-title":"Surgery in early metastatic seminoma: a phase II trial of retroperitoneal lymph node dissection for testicular seminoma with limited retroperitoneal lymphadenopathy","volume":"41","author":"Daneshmand","year":"2023","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0003","doi-asserted-by":"crossref","DOI":"10.1200\/JCO.22.01822","article-title":"Primary retroperitoneal lymph node dissection for stage II seminoma: is surgery the new path forward?","author":"Tachibana","year":"2023","journal-title":"J Clin Oncol"},{"issue":"1","key":"10.1016\/j.urolonc.2023.10.008_bib0004","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.eururo.2022.10.021","article-title":"Phase 2 single-arm trial of primary retroperitoneal lymph node dissection in patients with seminomatous testicular germ cell tumors with clinical stage IIA\/B (PRIMETEST)","volume":"84","author":"Hiester","year":"2023","journal-title":"Eur Urol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0005","article-title":"Retroperitoneal lymph node dissection in clinical stage IIA\/B metastatic seminoma: results of the COlogne trial of retroperitoneal lymphadenectomy in metastatic seminoma (COTRIMS)","author":"Heidenreich","year":"2023","journal-title":"Eur Urol Oncol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0006","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0007","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/XEB.0000000000000054","article-title":"Methodological guidance for systematic reviews of observational epidemiological studies reporting prevalence and cumulative incidence data","volume":"13","author":"Munn","year":"2015","journal-title":"Int J Evid Based Healthc"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0008","doi-asserted-by":"crossref","first-page":"e194","DOI":"10.1016\/j.clgc.2019.10.018","article-title":"Retroperitoneal lymph node dissection as primary treatment for men with testicular seminoma: utilization and survival analysis using the national cancer data base, 2004-2014","volume":"18","author":"Tabakin","year":"2020","journal-title":"Clin Genitourin Cancer"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0009","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.urology.2014.05.054","article-title":"Surgical management of late relapse on surveillance in patients presenting with clinical stage I testicular cancer","volume":"84","author":"Rice","year":"2014","journal-title":"Urology"},{"issue":"4","key":"10.1016\/j.urolonc.2023.10.008_bib0010","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1177\/03008916221112697","article-title":"Retroperitoneal lymph-node dissection (RPLND) as upfront management in stage II germ-cell tumours: evaluation of safety and efficacy","volume":"109","author":"Nicolai","year":"2023","journal-title":"Tumori"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0011","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1097\/JU.0000000000001301","article-title":"Robotic assisted retroperitoneal lymph node dissection for small volume metastatic testicular cancer","volume":"204","author":"Hiester","year":"2020","journal-title":"J Urol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0012","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/andr.13317","article-title":"Evaluation of miR-371a-3p to predict viable germ cell tumor in patients with pure seminoma receiving retroperitoneal lymph node dissection","volume":"11","author":"Konneh","year":"2023","journal-title":"androl"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0013","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1590\/s1677-5538.ibju.2022.0370","article-title":"Primary laparoscopic RPLND for pure seminona metastasis: feasibility of supine and lateral approaches","volume":"49","author":"Santos","year":"2023","journal-title":"Int Braz J Urol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0014","doi-asserted-by":"crossref","first-page":"e265","DOI":"10.1016\/j.clgc.2015.01.002","article-title":"Retroperitoneal lymph node dissection as first-line treatment of node-positive seminoma","volume":"13","author":"Hu","year":"2015","journal-title":"Clin Genitourin Cancer"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0015","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1007\/s11255-005-4793-x","article-title":"Retroperitoneal lymph node dissection for high-risk stage I and stage IIA seminoma","volume":"38","author":"Mezvrishvili","year":"2006","journal-title":"Int Urol Nephrol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0016","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3109\/00365599709030619","article-title":"Relapses in early-stage testicular seminoma: radiation therapy versus retroperitoneal lymphadenectomy","volume":"31","author":"Warszawski","year":"1997","journal-title":"Scand J Urol Nephrol"},{"issue":"Supplement 4","key":"10.1016\/j.urolonc.2023.10.008_bib0017","doi-asserted-by":"crossref","first-page":"e457","DOI":"10.1097\/JU.0000000000003266.18","article-title":"Surgical and oncologic outcomes of surgery in early metastatic seminoma: multi-institutional retrospective study","volume":"209","author":"Ladi-Seyedian","year":"2023","journal-title":"J Urol"},{"issue":"Supplement 4","key":"10.1016\/j.urolonc.2023.10.008_bib0018","doi-asserted-by":"crossref","first-page":"e451","DOI":"10.1097\/JU.0000000000003266.04","article-title":"The early results of the SWENOTECA (Swedish Norwegian Testicular Cancer Group) Introduction of Primary Retroperitoneal Lymph Node Dissection (RPLND) in seminoma stage IIA-IIB \u2264 3cm","volume":"209","author":"Thor","year":"2023","journal-title":"J Urol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/S0302-2838(23)00794-7","article-title":"Outcomes of minimally invasive retroperitoneal lymph node dissection (Primary MI- RPLND) followed by adjuvant carboplatin (AUC7) for clinical stage IIa\/b seminoma","volume":"83","author":"Cazzaniga","year":"2023","journal-title":"Eur Urol"},{"issue":"Supplement 4","key":"10.1016\/j.urolonc.2023.10.008_bib0020","doi-asserted-by":"crossref","first-page":"e688","DOI":"10.1097\/JU.0000000000003298.09","article-title":"Contemporary outcomes of primary extraperitoneal retroperitoneal lymph node dissection for stage II germ cell tumors","volume":"209","author":"Alsyouf","year":"2023","journal-title":"J Urol"},{"issue":"Supplement 4","key":"10.1016\/j.urolonc.2023.10.008_bib0021","first-page":"e1151","article-title":"Single institution experience with primary Rplnd for low-stage seminoma","volume":"203","author":"Matulewicz","year":"2020","journal-title":"J Urol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0022","doi-asserted-by":"crossref","first-page":"5008","DOI":"10.1200\/JCO.2023.41.16_suppl.5008","article-title":"Primary retroperitoneal lymph node dissection (RPLND) in seminoma stage IIA-IIC \u22643cm: combined results of the SWENOTECA (Swedish Norwegian Testicular Cancer Group) and cologne","volume":"41","author":"Tandstad","year":"2023","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0023","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1093\/annonc\/mdu447","article-title":"Radiotherapy or chemotherapy for clinical stage IIA and IIB seminoma: a systematic review and meta-analysis of patient outcomes","volume":"26","author":"Giannatempo","year":"2015","journal-title":"Ann Oncol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0024","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1200\/JCO.2017.77.0735","article-title":"Cumulative burden of morbidity among testicular cancer survivors after standard cisplatin-based chemotherapy: a multi-institutional study","volume":"36","author":"Kerns","year":"2018","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0025","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.euo.2019.06.007","article-title":"Nationwide patterns of care for stage II nonseminomatous germ cell tumor of the testicle","volume":"3","author":"Ghandour","year":"2020","journal-title":"Eur Urol Oncol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0026","unstructured":"Gilligan T, Lin DW, Aggarwal R, et al. Testicular Cancer, Version 1.2023, NCCN clinical practice guidelines in oncology. 2023. https:\/\/www.nccn.org\/login?ReturnURL=https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/testicular.pdf. Accessed June 1, 2023."},{"issue":"3","key":"10.1016\/j.urolonc.2023.10.008_bib0027","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.euf.2022.11.003","article-title":"Treatment outcomes for men with clinical stage II nonseminomatous germ cell tumours treated with primary retroperitoneal lymph node dissection: a systematic review","volume":"9","author":"Neuenschwander","year":"2023","journal-title":"Eur Urol Focus"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0028","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1200\/JCO.18.01480","article-title":"Serum levels of MicroRNA-371a-3p (M371 Test) as a new biomarker of testicular germ cell tumors: results of a prospective multicentric study","volume":"37","author":"Dieckmann","year":"2019","journal-title":"J Clin Oncol"},{"issue":"3","key":"10.1016\/j.urolonc.2023.10.008_bib0029","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.eururo.2023.04.010","article-title":"European Association of Urology Guidelines on Testicular Cancer: 2023 update","volume":"84","author":"Patrikidou","year":"2023","journal-title":"Eur Urol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0030","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s40644-022-00496-w","article-title":"Two decades of FDG-PET\/CT in seminoma: exploring its role in diagnosis, surveillance and follow-up","volume":"22","author":"Conduit","year":"2022","journal-title":"Cancer Imaging"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0031","doi-asserted-by":"crossref","DOI":"10.1097\/JU.0000000000003266.14","article-title":"Evaluation of miRNA-371a-3p (miR371a) assay to predict final pathohistoloy in patients undergoing primary nrerve-sparing retroperitoneal lymphadenectomy (nsRPLND) for Stage IIA\/B seminomas and non-seminomas","volume":"209","author":"Seelemeyer","year":"2023","journal-title":"J Urol"},{"key":"10.1016\/j.urolonc.2023.10.008_bib0032","unstructured":"A Prospective Observational Cohort Study to Assess miRNA371 for Outcome Prediction in Patients with Early Stage Germ Cell Tumors. https:\/\/www.swog.org\/clinical-trials\/s1823."},{"key":"10.1016\/j.urolonc.2023.10.008_bib0033","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1200\/JCO.22.02002","article-title":"Plasma Micro-RNA 371 expression in early-stage germ cell tumors: are we ready to move toward biology-based decision making?","volume":"41","author":"Alsyouf","year":"2023","journal-title":"J Clin Oncol"}],"container-title":["Urologic Oncology: Seminars and Original Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078143923003435?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1078143923003435?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T10:28:43Z","timestamp":1761042523000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1078143923003435"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":33,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S1078143923003435"],"URL":"https:\/\/doi.org\/10.1016\/j.urolonc.2023.10.008","relation":{},"ISSN":["1078-1439"],"issn-type":[{"type":"print","value":"1078-1439"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A systematic review of pN0 testicular seminoma: a new clinical entity and future directions","name":"articletitle","label":"Article Title"},{"value":"Urologic Oncology: Seminars and Original Investigations","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urolonc.2023.10.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}