{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T13:55:12Z","timestamp":1790344512768,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urologic Oncology: Seminars and Original Investigations"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.urolonc.2025.08.018","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T01:27:37Z","timestamp":1758590857000},"page":"69.e11-69.e17","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Microultrasound-targeted biopsies in patients with suspected prostate cancer: Diagnostic accuracy and clinical utility"],"prefix":"10.1016","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4306-7710","authenticated-orcid":false,"given":"Isabel","family":"Sanz G\u00f3mez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego Fernando","family":"Carvajal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Vega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Pellegrinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jhonatan Alfonso","family":"Esper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Anacleto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoni","family":"S\u00e0nchez-Puy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Tarrag\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Antonio","family":"Bellido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Miguel","family":"Marco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maida","family":"Bada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laia","family":"Sabiote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Gallardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William Andr\u00e9s","family":"Barrag\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Palazzetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelly Janneth","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Valverde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessio","family":"Zordani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Manuel","family":"Ulloa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bego\u00f1a","family":"Juaneda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul","family":"Martos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Salinas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Antonio","family":"Pe\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.urolonc.2025.08.018_bib0001","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.eururo.2019.08.005","article-title":"Recent global patterns in prostate cancer incidence and mortality rates","volume":"77","author":"Culp","year":"2020","journal-title":"Eur Urol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0002","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.cct.2015.02.008","article-title":"PROMIS\u2013prostate MR imaging study: a paired validating cohort study evaluating the role of multi-parametric MRI in men with clinical suspicion of prostate cancer","volume":"42","author":"El-Shater Bosaily","year":"2015","journal-title":"Contemp Clin Trials"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0003","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.euf.2019.11.006","article-title":"Can high resolution micro-ultrasound replace MRI in the diagnosis of prostate cancer?","volume":"6","author":"Laurence Klotz","year":"2020","journal-title":"Eur Urol Focus"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0004","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.eururo.2014.11.037","article-title":"Magnetic resonance imaging\u2013targeted biopsy may enhance the diagnostic accuracy of significant prostate cancer detection compared to standard transrectal ultrasound-guided biopsy: a systematic review and meta-analysis","volume":"68","author":"Schoots","year":"2015","journal-title":"Eur Urol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0005","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S1470-2045(18)30569-2","article-title":"Use of prostate systematic and targeted biopsy on the basis of multiparametric MRI in biopsy-naive patients (MRI-FIRST): a prospective, multicentre, paired diagnostic study","volume":"20","author":"Rouvi\u00e8re","year":"2019","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0006","first-page":"1","article-title":"Biopsy strategies in the era of mpMRI: a comprehensive review","author":"Windisch","year":"2024","journal-title":"Prostate Can Prostatic Dis"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0007","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1097\/JU.0000000000001639","article-title":"Micro-ultrasound-guided vs multiparametric Magnetic resonance imaging-targeted biopsy in the detection of prostate cancer: a systematic review and meta-analysis","volume":"205","author":"Sountoulides","year":"2021","journal-title":"J Urol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0008","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.euo.2018.10.001","article-title":"Comparison of the diagnostic accuracy of micro-ultrasound and magnetic resonance imaging\/ultrasound fusion targeted biopsies for the diagnosis of clinically significant prostate cancer","volume":"2","author":"Lughezzani","year":"2019","journal-title":"Eur Urol Oncol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0009","doi-asserted-by":"crossref","DOI":"10.3390\/cancers15041280","article-title":"Micro-Ultrasound: Current role in prostate cancer diagnosis and future possibilities","volume":"15","author":"Basso Dias","year":"2023","journal-title":"Cancers"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0010","doi-asserted-by":"crossref","first-page":"465","DOI":"10.48083\/10.48083\/DSVY1863","article-title":"Comparing the diagnostic performance of micro-ultrasound-guided biopsy versus multiparametric Magnetic resonance imaging-targeted biopsy in the detection of clinically significant prostate cancer: a systematic review and meta-analysis","volume":"4","author":"Org","year":"2023","journal-title":"Soc Int Urol J"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0011","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.juro.2015.12.093","article-title":"Assessing cancer risk on novel 29 MHz micro-ultrasound images of the prostate: creation of the micro-ultrasound protocol for prostate risk identification","volume":"196","author":"Ghai","year":"2016","journal-title":"J Urol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0012","doi-asserted-by":"crossref","first-page":"E11","DOI":"10.5489\/cuaj.6712","article-title":"Comparison of micro-ultrasound and multiparametric magnetic resonance imaging for prostate cancer: a multicenter, prospective analysis","volume":"15","author":"Klotz","year":"2020","journal-title":"Canadian Urolog Associat J"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0013","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1097\/JU.0000000000001639","article-title":"Micro-ultrasound\u2013Guided vs multiparametric magnetic resonance imaging-targeted biopsy in the detection of prostate cancer: a systematic review and meta-analysis","volume":"205","author":"Sountoulides","year":"2021","journal-title":"J Urol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0014","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1089\/end.2021.0361","article-title":"The microultrasound-guided prostate biopsy in detection of prostate cancer: a systematic review and meta-analysis","volume":"36","author":"You","year":"2022","journal-title":"J Endourol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0015","doi-asserted-by":"crossref","first-page":"832.e1","DOI":"10.1016\/j.urolonc.2021.05.030","article-title":"The use of 29 MHz transrectal micro-ultrasound to stratify the prostate cancer risk in patients with PI-RADS III lesions at multiparametric MRI: a single institutional analysis","volume":"39","author":"Avolio","year":"2021","journal-title":"Urol Oncol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0016","doi-asserted-by":"crossref","first-page":"E11","DOI":"10.5489\/cuaj.6712","article-title":"Comparison of micro-ultrasound and multiparametric magnetic resonance imaging for prostate cancer: a multicenter, prospective analysis","volume":"15","author":"Klotz","year":"2020","journal-title":"Canadian Urolog Associat J"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0017","article-title":"Microultrasonography-guided vs MRI-guided biopsy for prostate cancer diagnosis: the OPTIMUM randomized clinical trial","author":"Kinnaird","year":"2025","journal-title":"JAMA"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0018","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.eururo.2015.08.052","article-title":"PI-RADS Prostate Imaging \u2013 Reporting and Data system: 2015, version 2","volume":"69","author":"Weinreb","year":"2016","journal-title":"Eur Urol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0019","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.juro.2015.12.093","article-title":"Assessing cancer risk on novel 29 MHz micro-ultrasound images of the prostate: creation of the micro-ultrasound protocol for prostate risk identification","volume":"196","author":"Ghai","year":"2016","journal-title":"J Urol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0020","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.euf.2020.09.013","article-title":"Diagnostic accuracy of microultrasound in patients with a suspicion of prostate cancer at Magnetic resonance imaging: a single-institutional prospective study","volume":"7","author":"Lughezzani","year":"2021","journal-title":"Eur Urol Focus"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0021","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1056\/NEJMoa1801993","article-title":"MRI-targeted or standard biopsy for prostate-cancer diagnosis","volume":"378","author":"Kasivisvanathan","year":"2018","journal-title":"N Engl J Med"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0022","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.eururo.2018.12.004","article-title":"Multiparametric Magnetic resonance imaging for prostate cancer detection: what we see and what we miss","volume":"75","author":"Padhani","year":"2019","journal-title":"Eur Urol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0023","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.eururo.2018.03.007","article-title":"Negative multiparametric Magnetic resonance imaging for prostate cancer: what\u2019s next?","volume":"74","author":"Panebianco","year":"2018","journal-title":"Eur Urol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0024","doi-asserted-by":"crossref","first-page":"62","DOI":"10.48083\/KKVJ7280","article-title":"Prostate cancer detection by novice micro-ultrasound users enrolled in a training program","volume":"3","author":"Org","year":"2022","journal-title":"Soci\u00e9t\u00e9 Internationale d\u2019Urologie Journal"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0025","doi-asserted-by":"crossref","first-page":"465","DOI":"10.48083\/10.48083\/DSVY1863","article-title":"Comparing the diagnostic performance of micro-ultrasound-guided biopsy versus multiparametric Magnetic resonance imaging-targeted biopsy in the detection of clinically significant prostate cancer: a systematic review and meta-analysis","volume":"4","author":"Org","year":"2023","journal-title":"Soc Int Urol J"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0026","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.euros.2022.11.015","article-title":"Assessing the role of high-resolution microultrasound among na\u00efve patients with negative multiparametric Magnetic resonance imaging and a persistently high suspicion of prostate cancer","volume":"47","author":"Avolio","year":"2023","journal-title":"Eur Urol Open Sci"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0027","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1097\/JU.0000000000001083","article-title":"Prostate mapping for cancer diagnosis: the Madrid protocol. Transperineal Prostate biopsies using multiparametric magnetic resonance imaging fusion and micro-ultrasound guided biopsies","volume":"204","author":"Socarr\u00e1s","year":"2020","journal-title":"J Urol"},{"key":"10.1016\/j.urolonc.2025.08.018_bib0028","doi-asserted-by":"crossref","DOI":"10.3390\/jcm11123473","article-title":"Could 68Ga-PSMA PET\/CT evaluation reduce the number of scheduled prostate biopsies in men enrolled in active surveillance protocols?","volume":"11","author":"Pepe","year":"2022","journal-title":"J Clin Med"}],"container-title":["Urologic Oncology: Seminars and Original Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S107814392500345X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S107814392500345X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T12:57:22Z","timestamp":1765285042000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S107814392500345X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S107814392500345X"],"URL":"https:\/\/doi.org\/10.1016\/j.urolonc.2025.08.018","relation":{},"ISSN":["1078-1439"],"issn-type":[{"value":"1078-1439","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Microultrasound-targeted biopsies in patients with suspected prostate cancer: Diagnostic accuracy and clinical utility","name":"articletitle","label":"Article Title"},{"value":"Urologic Oncology: Seminars and Original Investigations","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urolonc.2025.08.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}