{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T02:53:40Z","timestamp":1761447220014,"version":"build-2065373602"},"reference-count":10,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"US National Institutes of Health","doi-asserted-by":"publisher","award":["GM102130"],"award-info":[{"award-number":["GM102130"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Washington State University College of Veterinary Medicine"}],"content-domain":{"domain":["vaajournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Anaesthesia and Analgesia"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.vaa.2016.05.003","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T13:45:46Z","timestamp":1484142346000},"page":"370-374","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Relationship between the melanocortin-1 receptor (MC1R) variant R306ter and physiological responses to mechanical or thermal stimuli in Labrador Retriever dogs"],"prefix":"10.1016","volume":"44","author":[{"given":"Tania E.","family":"Perez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrina L.","family":"Mealey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neal S.","family":"Burke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara L.","family":"Grubb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael H.","family":"Court","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen A.","family":"Greene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaa.2016.05.003_bib1","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1532-950X.2014.12112.x","article-title":"Learning confounds algometric assessment of mechanical thresholds in normal dogs","volume":"43","author":"Coleman","year":"2014","journal-title":"Vet Surg"},{"key":"10.1016\/j.vaa.2016.05.003_bib2","doi-asserted-by":"crossref","first-page":"e12498","DOI":"10.1371\/journal.pone.0012498","article-title":"Involvement of the melanocortin-1 receptor in acute pain and pain of inflammatory but not neuropathic origin","volume":"5","author":"Delaney","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.vaa.2016.05.003_bib3","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1046\/j.1365-2052.2000.00639.x","article-title":"Identification of a premature stop codon in the melanocyte-stimulating hormone receptor gene (MC1R) in Labrador and Golden retrievers with yellow coat colour","volume":"31","author":"Everts","year":"2000","journal-title":"Anim Genet"},{"key":"10.1016\/j.vaa.2016.05.003_bib4","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1186\/1746-6148-8-206","article-title":"Contact heat thermal threshold testing in beagle dogs: baseline reproducibility and the effect of acepromazine, levomethoadone and fenpipramide","volume":"8","author":"Hoffmann","year":"2012","journal-title":"BMC Vet Res"},{"key":"10.1016\/j.vaa.2016.05.003_bib5","first-page":"75","article-title":"Exclusion of melanocortin-1 receptor (MC1R) and agouti as candidates for dominant black in dogs","volume":"94","author":"Kerns","year":"2003","journal-title":"J\u00a0Hered"},{"key":"10.1016\/j.vaa.2016.05.003_bib6","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1097\/00000542-200408000-00006","article-title":"Anesthetic requirement is increased in redheads","volume":"101","author":"Liem","year":"2004","journal-title":"Anesthesiology"},{"key":"10.1016\/j.vaa.2016.05.003_bib7","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1097\/00000542-200503000-00006","article-title":"Increased sensitivity to thermal pain and reduced subcutaneous lidocaine efficacy in redheads","volume":"102","author":"Liem","year":"2005","journal-title":"Anesthesiology"},{"key":"10.1016\/j.vaa.2016.05.003_bib8","doi-asserted-by":"crossref","first-page":"4867","DOI":"10.1073\/pnas.0730053100","article-title":"The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans","volume":"100","author":"Mogil","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.vaa.2016.05.003_bib9","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1007\/s00335-001-2147-2","article-title":"TYRP1 and MC1R genotypes and their effects on coat color in dogs","volume":"13","author":"Schmutz","year":"2002","journal-title":"Mamm Genome"},{"key":"10.1016\/j.vaa.2016.05.003_bib10","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0014-2999(99)00298-8","article-title":"Melanocortin receptors: perspectives for novel drugs","volume":"375","author":"Wikberg","year":"1999","journal-title":"Eur J Pharmacol"}],"container-title":["Veterinary Anaesthesia and Analgesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298717300120?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298717300120?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T02:48:58Z","timestamp":1761446938000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1467298717300120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["S1467298717300120"],"URL":"https:\/\/doi.org\/10.1016\/j.vaa.2016.05.003","relation":{},"ISSN":["1467-2987"],"issn-type":[{"type":"print","value":"1467-2987"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relationship between the melanocortin-1 receptor (MC1R) variant R306ter and physiological responses to mechanical or thermal stimuli in Labrador Retriever dogs","name":"articletitle","label":"Article Title"},{"value":"Veterinary Anaesthesia and Analgesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaa.2016.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}