{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T03:02:58Z","timestamp":1761447778835,"version":"build-2065373602"},"reference-count":8,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100006623","name":"San Francisco Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006623","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003516","name":"Winn Feline Foundation","doi-asserted-by":"publisher","award":["MT15-006"],"award-info":[{"award-number":["MT15-006"]}],"id":[{"id":"10.13039\/100003516","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012429","name":"School of Veterinary Medicine, Louisiana State University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012429","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["vaajournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Anaesthesia and Analgesia"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.vaa.2019.05.002","type":"journal-article","created":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T17:45:52Z","timestamp":1560015952000},"page":"658-661","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of \u03b12-adrenoceptor antagonism on the minimum alveolar concentration of isoflurane in cats"],"prefix":"10.1016","volume":"46","author":[{"given":"Bruno H.","family":"Pypendop","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna","family":"Ahokoivu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juhana","family":"Honkavaara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaa.2019.05.002_bib1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0022-3565(25)22301-1","article-title":"A\u00a0peripherally acting alpha-2 adrenoceptor antagonist: L-659,066","volume":"245","author":"Clineschmidt","year":"1988","journal-title":"J\u00a0Pharmacol Exp Ther"},{"key":"10.1016\/j.vaa.2019.05.002_bib2","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1213\/01.ANE.0000061584.25288.98","article-title":"Alpha-2 adrenoreceptors probably do not mediate the immobility produced by inhaled anesthetics","volume":"96","author":"Eger","year":"2003","journal-title":"Anesth Analg"},{"key":"10.1016\/j.vaa.2019.05.002_bib3","doi-asserted-by":"crossref","first-page":"294","DOI":"10.2460\/ajvr.1993.54.02.294","article-title":"Reduction of isoflurane anesthetic requirement by medetomidine and its restoration by atipamezole in dogs","volume":"54","author":"Ewing","year":"1993","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.vaa.2019.05.002_bib4","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.vaa.2016.12.058","article-title":"Effects of constant rate infusions of dexmedetomidine or MK-467 on the minimum alveolar concentration of sevoflurane in dogs","volume":"44","author":"Hector","year":"2017","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2019.05.002_bib5","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/vaa.12385","article-title":"The effect of MK-467, a peripheral alpha2-adrenoceptor antagonist, on dexmedetomidine-induced sedation and bradycardia after intravenous administration in conscious cats","volume":"44","author":"Honkavaara","year":"2017","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2019.05.002_bib6","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.vaa.2019.02.004","article-title":"Effects of dexmedetomidine, with or without vatinoxan (MK-467) on the minimum alveolar concentration of isoflurane in cats","volume":"46","author":"Pypendop","year":"2019","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2019.05.002_bib7","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1097\/00000542-198010000-00008","article-title":"Determination and applications of MAC","volume":"53","author":"Quasha","year":"1980","journal-title":"Anesthesiology"},{"key":"10.1016\/j.vaa.2019.05.002_bib8","first-page":"29","article-title":"Pharmacological profiles of medetomidine and its antagonist, atipamezole","volume":"85","author":"Virtanen","year":"1989","journal-title":"Acta Vet Scand Suppl"}],"container-title":["Veterinary Anaesthesia and Analgesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298719301229?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298719301229?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T02:57:37Z","timestamp":1761447457000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1467298719301229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["S1467298719301229"],"URL":"https:\/\/doi.org\/10.1016\/j.vaa.2019.05.002","relation":{},"ISSN":["1467-2987"],"issn-type":[{"type":"print","value":"1467-2987"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of \u03b12-adrenoceptor antagonism on the minimum alveolar concentration of isoflurane in cats","name":"articletitle","label":"Article Title"},{"value":"Veterinary Anaesthesia and Analgesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaa.2019.05.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}