{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:16:46Z","timestamp":1778617006405,"version":"3.51.4"},"reference-count":34,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordination for the Improvement of Higher Education Personnel","doi-asserted-by":"publisher","award":["14835126"],"award-info":[{"award-number":["14835126"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"S\u00e3o Paulo Research Foundation","doi-asserted-by":"publisher","award":["FAPESP 2012\/00724-6"],"award-info":[{"award-number":["FAPESP 2012\/00724-6"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Anaesthesia and Analgesia"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.vaa.2020.09.001","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T02:11:00Z","timestamp":1600654260000},"page":"82-91","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of chemical restraint, isoflurane anesthesia and methadone or tramadol as preventive analgesia in spotted pacas (Cuniculus paca) subjected to laparoscopy"],"prefix":"10.1016","volume":"48","author":[{"given":"Ricardo AR.","family":"Uscategui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe FPC.","family":"Barros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00edvian T.","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline E.","family":"Kawanami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus AR.","family":"Feliciano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilter RR.","family":"Vicente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaa.2020.09.001_bib1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ijvsm.2013.12.004","article-title":"Synergistic efficacy of tramadol and meloxicam on alleviation of pain and selected immunological variables after sciatic nerve ligation in rats","volume":"2","author":"Abass","year":"2014","journal-title":"Int J Vet Sci Med"},{"key":"10.1016\/j.vaa.2020.09.001_bib2","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1590\/1678-4162-8756","article-title":"Laparoscopic ova collection in spotted paca (Cuniculus paca)","volume":"68","author":"Barros","year":"2016","journal-title":"Arq Bras Med Vet Zootec"},{"key":"10.1016\/j.vaa.2020.09.001_bib3","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1186\/s12917-014-0194-7","article-title":"Evaluation of the effects of methadone and tramadol on postoperative analgesia and serum interleukin-6 in dogs undergoing orthopaedic surgery","volume":"10","author":"Cardozo","year":"2014","journal-title":"BMC Vet Res"},{"key":"10.1016\/j.vaa.2020.09.001_bib4","series-title":"Livro Vermelho da Fauna Brasileira Amea\u00e7ada de Extin\u00e7\u00e3o.","first-page":"680","article-title":"Mam\u00edferos Amea\u00e7ados de Extin\u00e7\u00e3o no Brasil (Brazil endangered mammals)","author":"Chiarello","year":"2008"},{"key":"10.1016\/j.vaa.2020.09.001_bib5","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1467-2995.2010.00528.x","article-title":"Effects of methadone on the minimum alveolar concentration of isoflurane in dogs","volume":"37","author":"Credie","year":"2010","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2020.09.001_bib6","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/bja\/85.1.109","article-title":"The stress response to trauma and surgery","volume":"85","author":"Desborough","year":"2000","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.vaa.2020.09.001_bib7","doi-asserted-by":"crossref","first-page":"945","DOI":"10.2460\/ajvr.70.8.945","article-title":"Effect of intravenous administration of tramadol hydrochloride on the minimum alveolar concentration of isoflurane in rabbits","volume":"70","author":"Egger","year":"2009","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.vaa.2020.09.001_bib8","series-title":"The IUCN Red List of Threatened Species 2016","article-title":"Cuniculus paca","author":"Emmons","year":"2016"},{"key":"10.1016\/j.vaa.2020.09.001_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0152546","article-title":"Effects of methadone on the minimum anesthetic concentration of isoflurane, and its effects on heart rate, blood pressure and ventilation during isoflurane anesthesia in hens (Gallus gallus domesticus)","volume":"11","author":"Escobar","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.vaa.2020.09.001_bib10","first-page":"102","article-title":"Indicadores morfo-fisiol\u00f3gicos de la especie Agouti paca en cautiverio (Morpho-physiological indicators of the captive Agouti paca)","volume":"8","author":"Estrada","year":"2011","journal-title":"Momentos de Ciencia"},{"key":"10.1016\/j.vaa.2020.09.001_bib11","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.jss.2004.05.016","article-title":"Videoendoscopic endotracheal intubation in the rat: a comprehensive rodent model of laparoscopic surgery","volume":"122","author":"Fuentes","year":"2004","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.vaa.2020.09.001_bib12","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.tvjl.2012.03.019","article-title":"Cardiorespiratory and neuroendocrine changes induced by methadone in conscious and in isoflurane anaesthetised dogs","volume":"194","author":"Garofalo","year":"2012","journal-title":"Vet J"},{"key":"10.1016\/j.vaa.2020.09.001_bib13","series-title":"Zoo Animal and Wildlife Immobilization and Anesthesia","first-page":"3","article-title":"Clinical pharmacology","author":"Grimm","year":"2007"},{"key":"10.1016\/j.vaa.2020.09.001_bib14","series-title":"Lumb & Jones Veterinary Anesthesia and Analgesia","first-page":"86","article-title":"Monitoring anesthetized patients","author":"Haskins","year":"2015"},{"key":"10.1016\/j.vaa.2020.09.001_bib16","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.jeas.2006.09.003","article-title":"Partially antagonisable anaesthesia of the small hedgehog tenrec (Echinops telfairi) with medetomidine, midazolam and ketamine","volume":"43","author":"Henke","year":"2006","journal-title":"J\u00a0Exp Anim Sci"},{"key":"10.1016\/j.vaa.2020.09.001_bib15","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1439-0442.2004.00632.x","article-title":"Anaesthesia with midazolam\/medetomidine\/fentanyl in chinchillas (Chinchilla lanigera) compared to anaesthesia with xylazine\/ketamine and medetomidine\/ketamine","volume":"51","author":"Henke","year":"2004","journal-title":"J\u00a0Vet Med A Physiol Pathol Clin Med"},{"key":"10.1016\/j.vaa.2020.09.001_bib17","series-title":"Veterinary Anaesthesia","first-page":"570","article-title":"Chemical immobilization of wild animals","author":"Hernandez","year":"2014"},{"key":"10.1016\/j.vaa.2020.09.001_bib18","series-title":"Zoo and Wild Animal Medicine","first-page":"449","article-title":"Assisted reproductive techniques in nondomestic carnivores","author":"Howard","year":"1999"},{"key":"10.1016\/j.vaa.2020.09.001_bib19","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1097\/00005344-199610000-00006","article-title":"Effects of isoflurane on cardiovascular system and sympathovagal balance in New Zealand white rabbits","volume":"28","author":"Marano","year":"1996","journal-title":"J\u00a0Cardiovasc Pharmacol"},{"key":"10.1016\/j.vaa.2020.09.001_bib20","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1053\/j.saep.2005.09.010","article-title":"Tramadol","volume":"14","author":"Myers","year":"2005","journal-title":"Semin Avian Exot Pet Med"},{"key":"10.1016\/j.vaa.2020.09.001_bib21","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1093\/bja\/76.5.640","article-title":"Laparoscopic cholecystectomy: haemodynamic and neuroendocrine responses after pneumoperitoneum and changes in position","volume":"76","author":"O\u2019Leary","year":"1996","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.vaa.2020.09.001_bib22","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1590\/S0103-84782003000300024","article-title":"Hemi-ovariossalpingohisterectomia em pacas prenhes e posterior ocorr\u00eancia de prenhez (Agouti paca, Linnaeus, 1766) (Hemiovarysalpingohysterectomy in pregnant pacas and further occurrence of pregnancy (Agouti paca, Linnaeus, 1766)","volume":"33","author":"Oliveira","year":"2003","journal-title":"Cienc Rural"},{"key":"10.1016\/j.vaa.2020.09.001_bib23","first-page":"254","article-title":"The parasympatholytic effects of atropine sulfate and glycopyrrolate in rats and rabbits","volume":"58","author":"Olson","year":"1994","journal-title":"Can J Vet Res"},{"key":"10.1016\/j.vaa.2020.09.001_bib24","first-page":"303","article-title":"Restraint of the paca (Agouti paca) with ketamine hydrochloride, acetylpromazine maleate, and atropine sulfate","volume":"29","author":"Pachaly","year":"1998","journal-title":"J\u00a0Zoo Wildl Med"},{"key":"10.1016\/j.vaa.2020.09.001_bib25","series-title":"Biology, Medicine, and Surgery of South American Wild Animals","first-page":"225","article-title":"Order Rodentia (rodents)","author":"Pachaly","year":"2001"},{"key":"10.1016\/j.vaa.2020.09.001_bib26","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1378\/chest.110.3.810","article-title":"Cardiopulmonary physiology and pathophysiology as a consequence of laparoscopic surgery","volume":"110","author":"Sharma","year":"1996","journal-title":"Chest"},{"key":"10.1016\/j.vaa.2020.09.001_bib27","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.cvex.2010.09.005","article-title":"Tramadol use in zoologic medicine","volume":"14","author":"Souza","year":"2011","journal-title":"Vet Clin North Am Exot Anim Pract"},{"key":"10.1016\/j.vaa.2020.09.001_bib28","first-page":"107","article-title":"The electrocardiogram, vectorcardiogram and spatiocardiogram in the rabbit","volume":"35","author":"Szabuniewicz","year":"1971","journal-title":"Can J Comp Med"},{"key":"10.1016\/j.vaa.2020.09.001_bib29","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1097\/00000542-196011000-00011","article-title":"The effect of carbon dioxide on neurohumoral and endocrine mechanisms","volume":"21","author":"Tenney","year":"1960","journal-title":"Anesthesiology"},{"key":"10.1016\/j.vaa.2020.09.001_bib30","doi-asserted-by":"crossref","first-page":"39","DOI":"10.17533\/udea.rccp.v30n1a05","article-title":"Pre-emptive methadone or tramadol analgesia for mastectomy and ovariohysterectomy in bitches","volume":"30","author":"Uscategui","year":"2017","journal-title":"Rev Colomb Cienc Pecu"},{"key":"10.1016\/j.vaa.2020.09.001_bib31","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1590\/1678-4162-10552","article-title":"Hematological and biochemical parameters in Spotted Paca (Cuniculus paca) undergoing pharmacological restraint and general anesthesia","volume":"71","author":"Uscategui","year":"2019","journal-title":"Arq Bras Med Vet Zootec"},{"issue":"Suppl","key":"10.1016\/j.vaa.2020.09.001_bib32","first-page":"23","article-title":"Associa\u00e7\u00e3o de midazolam ao cloridrato de cetamina e cloridrato de xilazina para conten\u00e7\u00e3o farmacol\u00f3gica de pacas (Agouti paca) (Midazolam-ketamine-xylazine association for pharmacological restraint of pacas (Agouti paca))","volume":"41","author":"Vilani","year":"2004","journal-title":"Braz J Vet Res Anim Sci"},{"key":"10.1016\/j.vaa.2020.09.001_bib33","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1093\/bja\/83.5.780","article-title":"Effects of tramadol on minimum alveolar concentration (MAC) of isoflurane in rats","volume":"83","author":"Wolff","year":"1999","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.vaa.2020.09.001_bib34","series-title":"Fowler's Zoo and Wild Animal Medicine","first-page":"384","article-title":"Rodentia","author":"Yarto-Jaramillo","year":"2015"}],"container-title":["Veterinary Anaesthesia and Analgesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298720302075?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298720302075?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T19:37:48Z","timestamp":1778614668000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1467298720302075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S1467298720302075"],"URL":"https:\/\/doi.org\/10.1016\/j.vaa.2020.09.001","relation":{},"ISSN":["1467-2987"],"issn-type":[{"value":"1467-2987","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of chemical restraint, isoflurane anesthesia and methadone or tramadol as preventive analgesia in spotted pacas (Cuniculus paca) subjected to laparoscopy","name":"articletitle","label":"Article Title"},{"value":"Veterinary Anaesthesia and Analgesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaa.2020.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}