{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T13:55:59Z","timestamp":1792418159648,"version":"4.4.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["vaajournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Anaesthesia and Analgesia"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.vaa.2024.06.011","type":"journal-article","created":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T07:28:55Z","timestamp":1719559735000},"page":"475-481","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Comparison of the effects of intranasal and intramuscular midazolam\u2013butorphanol\u2013ketamine on intraocular pressure, tear production and sedation in New Zealand White rabbits"],"prefix":"10.1016","volume":"51","author":[{"given":"Harun","family":"Cinar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Latif Emrah","family":"Yanmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaa.2024.06.011_bib1","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.17582\/journal.aavs\/2019\/7.11.1015.1020","article-title":"Effect of xylazine HCl and\/or ketamine HCl on the Tear production in clinically healthy dogs","volume":"7","author":"Abdelhakiem","year":"2019","journal-title":"Adv Anim Vet Sci"},{"key":"10.1016\/j.vaa.2024.06.011_bib2","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.vaa.2018.10.007","article-title":"Pain and analgesia in pet rabbits within the veterinary environment: a review","volume":"46","author":"Benato","year":"2019","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2024.06.011_bib3","first-page":"1","article-title":"Application of rabbits in biomedical research: a review","volume":"14","author":"Bosze","year":"2006","journal-title":"World Rabbit Sci"},{"key":"10.1016\/j.vaa.2024.06.011_bib4","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1136\/vr.105491","article-title":"Postanaesthetic effects of ketamine\u2013midazolam and ketamine\u2013medetomidine on gastrointestinal transit time in rabbits anaesthetised with isoflurane","volume":"186","author":"Botman","year":"2020","journal-title":"Vet Rec"},{"key":"10.1016\/j.vaa.2024.06.011_bib5","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.jtos.2014.02.002","article-title":"Rethinking dry eye disease: a perspective on clinical implications","volume":"12","author":"Bron","year":"2014","journal-title":"Ocul Surf"},{"key":"10.1016\/j.vaa.2024.06.011_bib6","article-title":"The effect of intranasal medetomidine\/ketamine and diazepam\/ketamine combinations on tear production and intraocular pressure in dogs","volume":"53","author":"Bulut","year":"2023","journal-title":"Thai J Vet Med"},{"key":"10.1016\/j.vaa.2024.06.011_bib7","doi-asserted-by":"crossref","first-page":"905","DOI":"10.5433\/1679-0359.2014v35n2p905","article-title":"Dissociative anesthetic combination reduces intraocular pressure (IOP) in rabbits","volume":"35","author":"de Mattos","year":"2014","journal-title":"Semina Ci\u00eanc Agr\u00e1r"},{"key":"10.1016\/j.vaa.2024.06.011_bib8","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1111\/vop.12530","article-title":"Effect of sedation with butorphanol on variables pertaining to the ophthalmic examination in dogs","volume":"21","author":"Douet","year":"2018","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.vaa.2024.06.011_bib9","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.cvex.2021.08.012","article-title":"Rabbit sedation and anesthesia","volume":"25","author":"Gardhouse","year":"2022","journal-title":"Vet Clin Exot Anim Pract"},{"key":"10.1016\/j.vaa.2024.06.011_bib10","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1136\/vr.164.5.147","article-title":"Effects of intramuscular acepromazine and diazepam on tear production in rabbits","volume":"164","author":"Ghaffari","year":"2009","journal-title":"Vet Rec"},{"key":"10.1016\/j.vaa.2024.06.011_bib11","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.pharmthera.2012.03.003","article-title":"Intranasal drug delivery: an efficient and non-invasive route for systemic administration: focus on opioids","volume":"134","author":"Grassin-Delyle","year":"2012","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.vaa.2024.06.011_bib12","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1467-2995.2007.00362.x","article-title":"A\u00a0comparison of ketamine\u2013midazolam and ketamine\u2013medetomidine combinations for induction of anaesthesia in rabbits","volume":"35","author":"Grint","year":"2008","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2024.06.011_bib13","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.2460\/ajvr.67.7.1136","article-title":"Effects of ketamine, diazepam, and their combination on intraocular pressures in clinically normal dogs","volume":"67","author":"Hofmeister","year":"2006","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.vaa.2024.06.011_bib14","doi-asserted-by":"crossref","first-page":"475","DOI":"10.30802\/AALAS-JAALAS-22-000038","article-title":"Intramuscular alfaxalone\u2013butorphanol\u2013midazolam compared with ketamine\u2013butorphanol\u2013midazolam in New Zealand White rabbits","volume":"61","author":"Knutson","year":"2022","journal-title":"J\u00a0Am Assoc Lab Anim Sci"},{"key":"10.1016\/j.vaa.2024.06.011_bib15","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1007\/s12325-018-0812-z","article-title":"Diurnal and 24-h intraocular pressures in glaucoma: monitoring strategies and impact on prognosis and treatment","volume":"35","author":"Konstas","year":"2018","journal-title":"Adv Ther"},{"key":"10.1016\/j.vaa.2024.06.011_bib16","doi-asserted-by":"crossref","first-page":"59","DOI":"10.4314\/ovj.v10i1.10","article-title":"Changes in intraocular pressure, horizontal pupil diameter, and tear production during the use of topical 1% cyclopentolate in cats and rabbits","volume":"10","author":"Kovalcuka","year":"2020","journal-title":"Open Vet J"},{"key":"10.1016\/j.vaa.2024.06.011_bib17","first-page":"152","article-title":"Comparative study of evaluation of pain on injection of propofol pretreatment with two different doses of butorphanol","volume":"17","author":"Mahajan","year":"2015","journal-title":"JK Sci"},{"key":"10.1016\/j.vaa.2024.06.011_bib18","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.3390\/ani13132076","article-title":"Intranasal atomization of ketamine, medetomidine and butorphanol in pet rabbits using a mucosal atomization device","volume":"13","author":"Mauthe von Degerfeld","year":"2023","journal-title":"Animals"},{"key":"10.1016\/j.vaa.2024.06.011_bib19","doi-asserted-by":"crossref","first-page":"5899","DOI":"10.12681\/jhvms.26572","article-title":"Effect of butorphanol with and without medetomidine on intraocular pressure in cats","volume":"74","author":"Mohammadi","year":"2023","journal-title":"J\u00a0Hellenic Vet Med Soc"},{"key":"10.1016\/j.vaa.2024.06.011_bib20","doi-asserted-by":"crossref","first-page":"413","DOI":"10.17221\/51\/2018-VETMED","article-title":"Influence of medetomidine, acepromazine, fentanyl and butorphanol on intraocular pressure and pupil size in healthy dogs","volume":"63","author":"Mrazova","year":"2018","journal-title":"Vet Med (Praha)"},{"key":"10.1016\/j.vaa.2024.06.011_bib21","series-title":"Guide for the Care and Use of Laboratory Animals","year":"2011"},{"key":"10.1016\/j.vaa.2024.06.011_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/vetr.2999","article-title":"Sedative and cardiopulmonary effects of intranasal butorphanol with midazolam or dexmedetomidine in New Zealand White rabbits","volume":"193","author":"Okur","year":"2023","journal-title":"Vet Rec"},{"key":"10.1016\/j.vaa.2024.06.011_bib23","doi-asserted-by":"crossref","first-page":"549","DOI":"10.30802\/AALAS-JAALAS-21-000002","article-title":"Development and testing of a sedation scale for use in rabbits (Oryctolagus cuniculus)","volume":"60","author":"Raulic","year":"2021","journal-title":"J\u00a0Am Assoc Lab Anim Sci"},{"key":"10.1016\/j.vaa.2024.06.011_bib24","first-page":"439","article-title":"Non-invasive strategies for nose-to-brain drug delivery","volume":"10","author":"Trevino","year":"2020","journal-title":"J\u00a0Clin Trials"},{"key":"10.1016\/j.vaa.2024.06.011_bib25","first-page":"600","article-title":"Administration of substances to laboratory animals: routes of administration and factors to consider","volume":"50","author":"Turner","year":"2011","journal-title":"J\u00a0Am Assoc Lab Anim Sci"},{"key":"10.1016\/j.vaa.2024.06.011_bib26","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1292\/jvms.21-0648","article-title":"Maximum volume of nasal administration using a mucosal atomization device without aspiration in Japanese White rabbits","volume":"84","author":"Wei","year":"2022","journal-title":"J\u00a0Vet Med Sci"},{"key":"10.1016\/j.vaa.2024.06.011_bib27","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/vaa.12408","article-title":"Clinical evaluation of intranasal medetomidine\u2013ketamine and medetomidine\u2013S (+)-ketamine for induction of anaesthesia in rabbits in two centres with two different administration techniques","volume":"44","author":"Weiland","year":"2017","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2024.06.011_bib28","first-page":"2007","article-title":"The effects of \u0130ntranasal, \u0130nhaled and systemic glucocorticoids on \u0130ntraocular pressure: a literature review","volume":"11","author":"Wijnants","year":"2022","journal-title":"J\u00a0Clin Med"},{"key":"10.1016\/j.vaa.2024.06.011_bib29","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/vop.12400","article-title":"Comparison of the effects of intranasal and intramuscular administrations of zolazepam\u2013tiletamine combination on intraocular pressure in cats","volume":"19","author":"Yanmaz","year":"2016","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.vaa.2024.06.011_bib30","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.vaa.2021.10.003","article-title":"Effects of intramuscular and intranasal administration of midazolam\u2013dexmedetomidine on sedation and some cardiopulmonary variables in New Zealand White rabbits","volume":"49","author":"Yanmaz","year":"2022","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2024.06.011_bib31","doi-asserted-by":"crossref","first-page":"267","DOI":"10.2174\/1871527315666151110124957","article-title":"Rabbit models of ocular diseases: new relevance for classical approaches","volume":"15","author":"Zernii","year":"2016","journal-title":"CNS Neurol Disord Drug Targets"}],"container-title":["Veterinary Anaesthesia and Analgesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298724001223?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298724001223?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T13:14:01Z","timestamp":1725542041000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1467298724001223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S1467298724001223"],"URL":"https:\/\/doi.org\/10.1016\/j.vaa.2024.06.011","relation":{},"ISSN":["1467-2987"],"issn-type":[{"value":"1467-2987","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of the effects of intranasal and intramuscular midazolam\u2013butorphanol\u2013ketamine on intraocular pressure, tear production and sedation in New Zealand White rabbits","name":"articletitle","label":"Article Title"},{"value":"Veterinary Anaesthesia and Analgesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaa.2024.06.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}