{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T20:26:03Z","timestamp":1787862363024,"version":"build-2784847793"},"reference-count":31,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:00:00Z","timestamp":1771200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011523","name":"College of Veterinary Medicine, University of Minnesota","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011523","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005825","name":"National Institute of Food and Agriculture","doi-asserted-by":"publisher","award":["7002796"],"award-info":[{"award-number":["7002796"]}],"id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Anaesthesia and Analgesia"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.vaa.2026.101205","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:22:01Z","timestamp":1771546921000},"page":"101205","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Utility of dynamic preload indices of hypovolemia in isoflurane-anesthetized horses"],"prefix":"10.1016","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6904-7316","authenticated-orcid":false,"given":"Jessica","family":"Byrne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alonso GP.","family":"Guedes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen","family":"Hickey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Hatschbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Walters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5434-3592","authenticated-orcid":false,"given":"Aaron","family":"Rendahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitlin","family":"Tearney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaa.2026.101205_bib1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.vaa.2019.08.004","article-title":"Dynamic prediction of fluid responsiveness during positive pressure ventilation: a review of the physiology underlying heart-lung interactions and a critical interpretation","volume":"47","author":"Araos","year":"2020","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2026.101205_bib2","first-page":"715","article-title":"AVMA guidelines for the euthanasia of animals: 2020 edition","volume":"242","year":"2020","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.vaa.2026.101205_bib3","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1111\/j.1399-6576.2011.02435.x","article-title":"Accuracy of the pleth variability index to predict fluid responsiveness depends on the perfusion index: plethysmography and fluid responsiveness","volume":"55","author":"Broch","year":"2011","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.vaa.2026.101205_bib4","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1097\/00000542-197608000-00005","article-title":"Hemodynamic monitoring: invasive techniques","volume":"45","author":"Buchbinder","year":"1976","journal-title":"Anesthesiology"},{"key":"10.1016\/j.vaa.2026.101205_bib5","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1093\/bja\/aen133","article-title":"Pleth variability index to monitor the respiratory variations in the pulse oximeter plethysmographic waveform amplitude and predict fluid responsiveness in the operating theatre","volume":"101","author":"Cannesson","year":"2008","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.vaa.2026.101205_bib6","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.vaa.2018.12.004","article-title":"Comparison of the diagnostic accuracy of dynamic and static preload indexes to predict fluid responsiveness in mechanically ventilated, isoflurane anesthetized dogs","volume":"46","author":"Celeita-Rodriguez","year":"2019","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2026.101205_bib7","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1213\/ANE.0b013e318240d6eb","article-title":"Perioperative fluid management strategies in major surgery: a stratified meta-analysis","volume":"114","author":"Corcoran","year":"2012","journal-title":"Anesth Analg"},{"key":"10.1016\/j.vaa.2026.101205_bib8","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.vaa.2021.01.009","article-title":"Comparison between pulse pressure variation and systolic pressure variation measured from a peripheral artery for accurately predicting fluid responsiveness in mechanically ventilated dogs","volume":"48","author":"Dalmagro","year":"2021","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2026.101205_bib9","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1214\/ss\/1032280214","article-title":"Bootstrap confidence intervals","volume":"11","author":"DiCiccio","year":"1996","journal-title":"Stat Sci"},{"key":"10.1016\/j.vaa.2026.101205_bib10","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/vec.12246","article-title":"Effects of dexmedetomidine on pulse pressure variation changes induced by hemorrhage followed by volume replacement in isoflurane-anesthetized dogs","volume":"24","author":"Diniz","year":"2014","journal-title":"J Vet Emerg Crit Care"},{"key":"10.1016\/j.vaa.2026.101205_bib11","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.vaa.2017.06.001","article-title":"Evaluation of the dynamic predictors of fluid responsiveness in dogs receiving goal-directed fluid therapy","volume":"45","author":"Drozdzynska","year":"2018","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2026.101205_bib12","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/j.vaa.2017.07.007","article-title":"Plethysmography variability index for prediction of fluid responsiveness during graded haemorrhage and transfusion in sevoflurane-anaesthetized mechanically ventilated dogs","volume":"44","author":"Endo","year":"2017","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2026.101205_bib13","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1292\/jvms.16-0287","article-title":"Stroke volume variation (SVV) and pulse pressure variation (PPV) as indicators of fluid responsiveness in sevoflurane anesthetized mechanically ventilated euvolemic dogs","volume":"79","author":"Endo","year":"2017","journal-title":"J Vet Med Sci"},{"key":"10.1016\/j.vaa.2026.101205_bib14","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/j.1476-4431.2012.00746.x","article-title":"Pulse pressure variation and systolic pressure variation in horses undergoing general anesthesia","volume":"22","author":"Fielding","year":"2012","journal-title":"J Vet Emerg Crit Care"},{"key":"10.1016\/j.vaa.2026.101205_bib15","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1213\/01.ANE.0000156681.36240.10","article-title":"Measurement of systolic pressure variation on a datex AS\/3 monitor","volume":"100","author":"Gouvea","year":"2005","journal-title":"Anesth Analg"},{"key":"10.1016\/j.vaa.2026.101205_bib16","doi-asserted-by":"crossref","first-page":"818","DOI":"10.2460\/ajvr.82.10.818","article-title":"Effect of thermodilution injectate volume and temperature on the accuracy and precision of cardiac output measurements for healthy anesthetized horses","volume":"82","author":"Jenny","year":"2021","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.vaa.2026.101205_bib17","doi-asserted-by":"crossref","first-page":"2858","DOI":"10.1097\/CCM.0b013e3181865aea","article-title":"Effect of tidal volume, sampling duration, and cardiac contractility on pulse pressure and stroke volume variation during positive-pressure ventilation","volume":"36","author":"Kim","year":"2008","journal-title":"Crit Care Med"},{"key":"10.1016\/j.vaa.2026.101205_bib18","doi-asserted-by":"crossref","first-page":"2642","DOI":"10.1097\/CCM.0b013e3181a590da","article-title":"Dynamic changes in arterial waveform derived variables and fluid responsiveness in mechanically ventilated patients: a systematic review of the literature","volume":"37","author":"Marik","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.vaa.2026.101205_bib19","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/j.1467-2995.2005.00273.x","article-title":"The effect of hypovolemia due to hemorrhage on the minimum alveolar concentration of isoflurane in the dog","volume":"33","author":"Mattson","year":"2006","journal-title":"Vet Anaesth Analg"},{"key":"10.1016\/j.vaa.2026.101205_bib20","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1164\/ajrccm.162.1.9903035","article-title":"Relation between respiratory changes in arterial pulse pressure and fluid responsiveness in septic patients with acute circulatory failure","volume":"162","author":"Michard","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.vaa.2026.101205_bib21","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/ki.1972.48","article-title":"The effects of acid-base disturbances on cardiovascular and pulmonary function","volume":"1","author":"Mitchell","year":"1972","journal-title":"Kidney Int"},{"key":"10.1016\/j.vaa.2026.101205_bib22","series-title":"Cardiovascular physiology","author":"Mohrman","year":"2014"},{"key":"10.1016\/j.vaa.2026.101205_bib23","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/s13613-016-0216-7","article-title":"Prediction of fluid responsiveness: an update","volume":"6","author":"Monnet","year":"2016","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.vaa.2026.101205_bib24","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1111\/eve.13527","article-title":"Controlled mechanical ventilation in equine anaesthesia: classification of ventilators and practical considerations (part 2)","volume":"34","author":"Moreno-Martinez","year":"2022","journal-title":"Equine Vet Educ"},{"key":"10.1016\/j.vaa.2026.101205_bib25","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1097\/01.CCM.0000182801.48137.13","article-title":"Effects of norepinephrine on static and dynamic preload indicators in experimental hemorrhagic shock","volume":"33","author":"Nouira","year":"2005","journal-title":"Crit Care Med"},{"key":"10.1016\/j.vaa.2026.101205_bib26","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0025-7125(16)30086-4","article-title":"Hypocalcemic emergencies","volume":"79","author":"Reber","year":"1995","journal-title":"Med Clin North Am"},{"key":"10.1016\/j.vaa.2026.101205_bib27","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/vec.12728","article-title":"Evaluation of pulse pressure variation and pleth variability index to predict fluid responsiveness in mechanically ventilated isoflurane-anesthetized dogs","volume":"28","author":"Sano","year":"2018","journal-title":"J Vet Emerg Crit Care (San Antonio)"},{"key":"10.1016\/j.vaa.2026.101205_bib28","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.2460\/ajvr.1977.38.07.1037","article-title":"Enflurane, halothane, and isoflurane potency in horses","volume":"38","author":"Steffey","year":"1977","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.vaa.2026.101205_bib29","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1097\/00000542-199812000-00007","article-title":"Systolic pressure variation as a guide to fluid therapy in patients with sepsis-induced hypotension","volume":"89","author":"Tavernier","year":"1998","journal-title":"Anesthesiology"},{"key":"10.1016\/j.vaa.2026.101205_bib30","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/ans.12102","article-title":"Management of prolonged post-operative ileus: evidence-based recommendations","volume":"83","author":"Vather","year":"2013","journal-title":"ANZ J Surg"},{"key":"10.1016\/j.vaa.2026.101205_bib31","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1097\/EJA.0b013e328335fbd1","article-title":"Accuracy of stroke volume variation compared with pleth variability index to predict fluid responsiveness in mechanically ventilated patients undergoing major surgery","volume":"27","author":"Zimmermann","year":"2010","journal-title":"Eur J Anaesthesiol"}],"container-title":["Veterinary Anaesthesia and Analgesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S146729872600019X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S146729872600019X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T20:14:31Z","timestamp":1787861671000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S146729872600019X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S146729872600019X"],"URL":"https:\/\/doi.org\/10.1016\/j.vaa.2026.101205","relation":{},"ISSN":["1467-2987"],"issn-type":[{"value":"1467-2987","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Utility of dynamic preload indices of hypovolemia in isoflurane-anesthetized horses","name":"articletitle","label":"Article Title"},{"value":"Veterinary Anaesthesia and Analgesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaa.2026.101205","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd on behalf of Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia.","name":"copyright","label":"Copyright"}],"article-number":"101205"}}