{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T20:14:37Z","timestamp":1792181677958,"version":"4.4.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"25-26","license":[{"start":{"date-parts":[[2004,9,1]],"date-time":"2004-09-01T00:00:00Z","timestamp":1093996800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2004,9]]},"DOI":"10.1016\/j.vaccine.2004.01.063","type":"journal-article","created":{"date-parts":[[2004,3,6]],"date-time":"2004-03-06T12:37:13Z","timestamp":1078576633000},"page":"3495-3502","source":"Crossref","is-referenced-by-count":84,"title":["Marburg virus-like particles protect guinea pigs from lethal Marburg virus infection"],"prefix":"10.1016","volume":"22","author":[{"given":"Kelly L","family":"Warfield","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana L","family":"Swenson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane L","family":"Negley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan L","family":"Schmaljohn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.Javad","family":"Aman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sina","family":"Bavari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2004.01.063_BIB1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/978-3-7091-9300-6_8","article-title":"Molecular biology and evolution of filoviruses","volume":"7","author":"Feldmann","year":"1993","journal-title":"Arch. Virol. Suppl."},{"key":"10.1016\/j.vaccine.2004.01.063_BIB2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-3527(08)60733-2","article-title":"Marburg and Ebola viruses","volume":"47","author":"Feldmann","year":"1996","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.vaccine.2004.01.063_BIB3","doi-asserted-by":"crossref","unstructured":"Martini GA, Seigert R, editor. Marburg virus disease. Berlin: Springer-Verlag; 1971.","DOI":"10.1007\/978-3-662-01593-3"},{"issue":"8276","key":"10.1016\/j.vaccine.2004.01.063_BIB4","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/S0140-6736(82)91871-2","article-title":"Marburg-virus disease in Kenya","volume":"1","author":"Smith","year":"1982","journal-title":"Lancet"},{"key":"10.1016\/j.vaccine.2004.01.063_BIB5","first-page":"32","article-title":"Survival of Marburg virus infectivity on contaminated surfaces and in aerosols","volume":"41","author":"Belanov","year":"1996","journal-title":"Vopr. Virusol."},{"key":"10.1016\/j.vaccine.2004.01.063_BIB6","unstructured":"Frolov VGAG, M. Stability of Marburg virus to lyophilization process and subsequent storage at different temperatures. Vopr. Virusol. 1996;41:275\u20137."},{"key":"10.1016\/j.vaccine.2004.01.063_BIB7","unstructured":"Alibek K, Handelsman S, Biohazard: random house. New York, NY, USA; 1999."},{"issue":"22","key":"10.1016\/j.vaccine.2004.01.063_BIB8","doi-asserted-by":"crossref","first-page":"11025","DOI":"10.1128\/JVI.75.22.11025-11033.2001","article-title":"Infection and activation of monocytes by Marburg and Ebola viruses","volume":"75","author":"Stroher","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.vaccine.2004.01.063_BIB9","doi-asserted-by":"crossref","unstructured":"Gibb TR, Norwood Jr DA, Woollen N, Henchal EA. Viral replication and host gene expression in alveolar macrophages infected with Ebola virus (Zaire strain). Clin Diagn Lab Immunol 2002;9(1):19\u201327.","DOI":"10.1128\/CDLI.9.1.19-27.2002"},{"issue":"11","key":"10.1016\/j.vaccine.2004.01.063_BIB10","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1086\/379199","article-title":"Ebola and marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation","volume":"188","author":"Bosio","year":"2003","journal-title":"J. Infect. Dis."},{"issue":"6","key":"10.1016\/j.vaccine.2004.01.063_BIB11","doi-asserted-by":"crossref","first-page":"2797","DOI":"10.4049\/jimmunol.170.6.2797","article-title":"Cutting edge: impairment of dendritic cells and adaptive immunity by Ebola and Lassa viruses","volume":"170","author":"Mahanty","year":"2003","journal-title":"J. Immunol."},{"issue":"4","key":"10.1016\/j.vaccine.2004.01.063_BIB12","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1128\/JVI.70.4.2208-2214.1996","article-title":"Filovirus-induced endothelial leakage triggered by infected monocytes\/macrophages","volume":"70","author":"Feldmann","year":"1996","journal-title":"J. Virol."},{"issue":"3","key":"10.1016\/j.vaccine.2004.01.063_BIB13","first-page":"106","article-title":"Dendritic cells and the control of immunity: enhancing the efficiency of antigen presentation","volume":"68","author":"Steinman","year":"2001","journal-title":"Mt. Sinai. J. Med."},{"key":"10.1016\/j.vaccine.2004.01.063_BIB14","doi-asserted-by":"crossref","unstructured":"Baize S, Leroy EM, Georges-Courbot MC, Capron M, Lansoud-Soukate J, Debre P, et al. Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients. Nat Med 1999;5(4):423\u20136.","DOI":"10.1038\/7422"},{"issue":"9222","key":"10.1016\/j.vaccine.2004.01.063_BIB15","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1016\/S0140-6736(00)02405-3","article-title":"Human asymptomatic Ebola infection and strong inflammatory response","volume":"355","author":"Leroy","year":"2000","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.vaccine.2004.01.063_BIB16","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1046\/j.1365-2249.2001.01517.x","article-title":"Early immune responses accompanying human asymptomatic Ebola infections","volume":"124","author":"Leroy","year":"2001","journal-title":"Clin. Exp. Immunol."},{"issue":"1","key":"10.1016\/j.vaccine.2004.01.063_BIB17","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1046\/j.1365-2249.2002.01800.x","article-title":"Inflammatory responses in Ebola virus-infected patients","volume":"128","author":"Baize","year":"2002","journal-title":"Clin. Exp. Immunol."},{"issue":"1","key":"10.1016\/j.vaccine.2004.01.063_BIB18","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1006\/viro.1997.8883","article-title":"Antigenicity and vaccine potential of Marburg virus glycoprotein expressed by baculovirus recombinants","volume":"239","author":"Hevey","year":"1997","journal-title":"Virology"},{"issue":"1","key":"10.1016\/j.vaccine.2004.01.063_BIB19","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1006\/viro.1998.9367","article-title":"Marburg virus vaccines based upon alphavirus replicons protect guinea pigs and nonhuman primates","volume":"251","author":"Hevey","year":"1998","journal-title":"Virology"},{"issue":"3\u20134","key":"10.1016\/j.vaccine.2004.01.063_BIB20","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/S0264-410X(01)00353-X","article-title":"Marburg virus vaccines: comparing classical and new approaches","volume":"20","author":"Hevey","year":"2001","journal-title":"Vaccine"},{"issue":"1\u20133","key":"10.1016\/j.vaccine.2004.01.063_BIB21","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0168-1656(95)00104-2","article-title":"Inactivated Marburg virus elicits a nonprotective immune response in Rhesus monkeys","volume":"44","author":"Ignatyev","year":"1996","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.vaccine.2004.01.063_BIB22","first-page":"421","article-title":"A comparative study of the immunological indices in guinea pigs administered an inactivated Marburg virus","volume":"36","author":"Ignatev","year":"1991","journal-title":"Vopr. Virusol."},{"issue":"25\u201326","key":"10.1016\/j.vaccine.2004.01.063_BIB23","doi-asserted-by":"crossref","first-page":"4071","DOI":"10.1016\/S0264-410X(03)00362-1","article-title":"Comparison of individual and combination DNA vaccines for B anthracis, Ebola virus, Marburg virus and Venezuelan equine encephalitis virus","volume":"21","author":"Riemenschneider","year":"2003","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.vaccine.2004.01.063_BIB24","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0959-440X(00)00073-7","article-title":"Structures of virus and virus-like particles","volume":"10","author":"Johnson","year":"2000","journal-title":"Curr. Opin. Struct. Biol."},{"issue":"13\u201314","key":"10.1016\/j.vaccine.2004.01.063_BIB25","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1016\/S0264-410X(98)00431-9","article-title":"Correlates of protection, antigen delivery and molecular epidemiology: basics for designing an HIV vaccine","volume":"17","author":"Wagner","year":"1999","journal-title":"Vaccine"},{"issue":"27","key":"10.1016\/j.vaccine.2004.01.063_BIB26","doi-asserted-by":"crossref","first-page":"3733","DOI":"10.1016\/S0264-410X(01)00093-7","article-title":"Antibody, cytokine and cytotoxic T lymphocyte responses in chimpanzees immunized with human papillomavirus virus-like particles","volume":"19","author":"Palker","year":"2001","journal-title":"Vaccine"},{"issue":"4","key":"10.1016\/j.vaccine.2004.01.063_BIB27","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1093\/jnci\/93.4.284","article-title":"Safety and immunogenicity trial in adult volunteers of a human papillomavirus 16 L1 virus-like particle vaccine","volume":"93","author":"Harro","year":"2001","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.vaccine.2004.01.063_BIB28","doi-asserted-by":"crossref","unstructured":"Bavari S, Bosio CM, Wiegand E, Ruthel G, Will AB, Geisbert TW, et al. Lipid raft microdomains: a gateway for compartmentalized trafficking of Ebola and Marburg viruses. J Exp Med 2002;195(5):593\u2013602.","DOI":"10.1084\/jem.20011500"},{"issue":"26","key":"10.1016\/j.vaccine.2004.01.063_BIB29","doi-asserted-by":"crossref","first-page":"15889","DOI":"10.1073\/pnas.2237038100","article-title":"Ebola virus-like particles protect from lethal Ebola virus infection","volume":"100","author":"Warfield","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.vaccine.2004.01.063_BIB30","doi-asserted-by":"crossref","unstructured":"Swenson DL, Warfield KL, Kuehl K, Larsen T, Hevey MC, Schmaljohn A, et al. Generation of Marburg virus-like particles by co-expression of glycoprotein and matrix protein. FEMS Immunol Med Microbiol, 2004;40(1):27\u201331.","DOI":"10.1016\/S0928-8244(03)00273-6"},{"key":"10.1016\/j.vaccine.2004.01.063_BIB31","doi-asserted-by":"crossref","unstructured":"Rao, M, Bray, M, Alving, CR, Jahrling, P, Matyas, GR. Induction of immune responses in mice and monkeys to Ebola virus after immunization with liposome-encapsulated irradiated Ebola virus: protection in mice requires CD4(+) T cells. J Virol 2002;76(18):9176\u201385.","DOI":"10.1128\/JVI.76.18.9176-9185.2002"},{"issue":"5458","key":"10.1016\/j.vaccine.2004.01.063_BIB32","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1126\/science.287.5458.1664","article-title":"Epitopes involved in antibody-mediated protection from Ebola virus","volume":"287","author":"Wilson","year":"2000","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.vaccine.2004.01.063_BIB33","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/nm0198-037","article-title":"Immunization for Ebola virus infection","volume":"4","author":"Xu","year":"1998","journal-title":"Nat. Med."},{"key":"10.1016\/j.vaccine.2004.01.063_BIB34","doi-asserted-by":"crossref","unstructured":"Wilson JA, Hart MK. Protection from Ebola virus mediated by cytotoxic T lymphocytes specific for the viral nucleoprotein. J Virol 2001;75(6):2660\u20134.","DOI":"10.1128\/JVI.75.6.2660-2664.2001"},{"issue":"1","key":"10.1016\/j.vaccine.2004.01.063_BIB35","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/S0042-6822(03)00416-1","article-title":"Characterization of monoclonal antibodies to Marburg virus (strain Musoke) glycoprotein and identification of two protective epitopes","volume":"314","author":"Hevey","year":"2003","journal-title":"Virology"},{"key":"10.1016\/j.vaccine.2004.01.063_BIB36","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0020-7519(03)00064-X","article-title":"Vaccine research efforts for filoviruses","volume":"33","author":"Hart","year":"2003","journal-title":"Int. J. Parasitol."},{"issue":"6812","key":"10.1016\/j.vaccine.2004.01.063_BIB37","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/35046108","article-title":"Development of a preventive vaccine for Ebola virus infection in primates","volume":"408","author":"Sullivan","year":"2000","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.vaccine.2004.01.063_BIB38","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S0167-5699(99)01447-4","article-title":"Cytotoxic T lymphocytes, chemokines and antiviral immunity","volume":"20","author":"Price","year":"1999","journal-title":"Immunol. Today"},{"issue":"1","key":"10.1016\/j.vaccine.2004.01.063_BIB39","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1006\/viro.1998.9176","article-title":"DNA vaccines expressing either the GP or NP genes of Ebola virus protect mice from lethal challenge","volume":"246","author":"Vanderzanden","year":"1998","journal-title":"Virology"},{"key":"10.1016\/j.vaccine.2004.01.063_BIB40","first-page":"205","article-title":"Immune response to filovirus infections","volume":"235","author":"Ignatev","year":"1999","journal-title":"Curr. Top. Microbiol. Immunol."},{"issue":"5","key":"10.1016\/j.vaccine.2004.01.063_BIB41","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1128\/JVI.75.5.2324-2330.2001","article-title":"Infectivity-enhancing antibodies to Ebola virus glycoprotein","volume":"75","author":"Takada","year":"2001","journal-title":"J. Virol."},{"issue":"13","key":"10.1016\/j.vaccine.2004.01.063_BIB42","doi-asserted-by":"crossref","first-page":"7539","DOI":"10.1128\/JVI.77.13.7539-7544.2003","article-title":"Antibody-dependent enhancement of Ebola virus infection","volume":"77","author":"Takada","year":"2003","journal-title":"J. Virol."},{"issue":"6","key":"10.1016\/j.vaccine.2004.01.063_BIB43","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1002\/rmv.405","article-title":"Antibody-dependent enhancement of viral infection: molecular mechanisms and in vivo implications","volume":"13","author":"Takada","year":"2003","journal-title":"Rev. Med. Virol."}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X04001604?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X04001604?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T14:30:14Z","timestamp":1585665014000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X04001604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,9]]},"references-count":43,"journal-issue":{"issue":"25-26","published-print":{"date-parts":[[2004,9]]}},"alternative-id":["S0264410X04001604"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2004.01.063","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2004,9]]}}}