{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T21:01:56Z","timestamp":1783803716631,"version":"3.55.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"36","license":[{"start":{"date-parts":[[2005,8,1]],"date-time":"2005-08-01T00:00:00Z","timestamp":1122854400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2005,8]]},"DOI":"10.1016\/j.vaccine.2005.04.017","type":"journal-article","created":{"date-parts":[[2005,5,10]],"date-time":"2005-05-10T21:49:22Z","timestamp":1115761762000},"page":"4517-4520","source":"Crossref","is-referenced-by-count":16,"title":["An immuno-diffusion assay to assess the protective antigen content of anthrax vaccine"],"prefix":"10.1016","volume":"23","author":[{"given":"Trudy","family":"Adams","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sancha","family":"Osborn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sjoerd","family":"Rijpkema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.vaccine.2005.04.017_bib1","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1056\/NEJM199909093411107","article-title":"Anthrax","volume":"341","author":"Dixon","year":"1999","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.vaccine.2005.04.017_bib2","doi-asserted-by":"crossref","first-page":"933","DOI":"10.3201\/eid0706.010604","article-title":"Bioterrorism-related inhalational anthrax: the first 10 cases reported in the United States","volume":"8","author":"Jernigan","year":"2001","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.vaccine.2005.04.017_bib3","first-page":"261","article-title":"Fatal case of inhalational anthrax mimicking intra-abdominal sepsis","volume":"66","author":"Quintiliani","year":"2002","journal-title":"Conn Med"},{"key":"10.1016\/j.vaccine.2005.04.017_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mib.2003.12.001","article-title":"The roles of anthrax toxin in pathogenesis","volume":"7","author":"Moayeri","year":"2004","journal-title":"Curr Opin Microbiol"},{"issue":"20","key":"10.1016\/j.vaccine.2005.04.017_bib5","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1001\/jama.286.20.2549","article-title":"Clinical presentation of inhalational anthrax following bioterrorism exposure: report of 2 surviving patients","volume":"286","author":"Mayer","year":"2001","journal-title":"JAMA"},{"issue":"4","key":"10.1016\/j.vaccine.2005.04.017_bib6","doi-asserted-by":"crossref","first-page":"632","DOI":"10.2105\/AJPH.52.4.632","article-title":"Field evaluation of a human anthrax vaccine","volume":"52","author":"Brachman","year":"1962","journal-title":"Am J Publ Health"},{"issue":"2","key":"10.1016\/j.vaccine.2005.04.017_bib7","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0264-410X(84)90003-3","article-title":"Anthrax: the disease in relation to vaccines","volume":"2","author":"Hambleton","year":"1984","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2005.04.017_bib8","first-page":"144","article-title":"Studies on a protective antigen produced in vitro from Bacillus anthracis: medium and methods of production","volume":"35","author":"Belton","year":"1954","journal-title":"Br J Exp Pathol"},{"key":"10.1016\/j.vaccine.2005.04.017_bib9","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1128\/JB.83.3.515-522.1962","article-title":"Studies on immunity in anthrax. IX. Effect of variations in cultural conditions on elaboration of protective antigen by strains of Bacillus anthracis","volume":"83","author":"Wright","year":"1962","journal-title":"J Bacteriol"},{"key":"10.1016\/j.vaccine.2005.04.017_bib10","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1128\/AEM.11.4.330-334.1963","article-title":"Large-scale production of protective antigen of Bacillus anthracis in anaerobic cultures","volume":"11","author":"Puzzis","year":"1963","journal-title":"Appl Microbiol"},{"key":"10.1016\/j.vaccine.2005.04.017_bib11","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1099\/00221287-17-2-505","article-title":"An agar-diffusion method for titrating Bacillus anthracis immunizing antigen and its application to a study of antigen production","volume":"17","author":"Thorne","year":"1957","journal-title":"J Gen Microbiol"},{"issue":"11\u201312","key":"10.1016\/j.vaccine.2005.04.017_bib12","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/S0264-410X(98)80112-6","article-title":"Comparative efficacy of experimental anthrax vaccine candidates against inhalation anthrax in rhesus macaques","volume":"16","author":"Ivins","year":"1998","journal-title":"Vaccine"},{"issue":"32","key":"10.1016\/j.vaccine.2005.04.017_bib13","doi-asserted-by":"crossref","first-page":"4768","DOI":"10.1016\/S0264-410X(01)00234-1","article-title":"In vitro correlate of immunity in a rabbit model of inhalational anthrax","volume":"19","author":"Pitt","year":"2001","journal-title":"Vaccine"},{"issue":"5","key":"10.1016\/j.vaccine.2005.04.017_bib14","doi-asserted-by":"crossref","first-page":"2888","DOI":"10.1128\/IAI.69.5.2888-2893.2001","article-title":"Search for correlates of protective immunity conferred by anthrax vaccine","volume":"69","author":"Reuveny","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2005.04.017_bib15","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/BF00189414","article-title":"Antibodies to anthrax toxin in humans and guinea pigs and their relevance to protective immunity","volume":"177","author":"Turnbull","year":"1988","journal-title":"Med Microbiol Immunol Berl"},{"key":"10.1016\/j.vaccine.2005.04.017_bib16","first-page":"89","article-title":"Protection conferred by microbially-supplemented UK and purified PA vaccines","volume":"68","author":"Turnbull","year":"1990","journal-title":"Salisbury Med Bull"},{"key":"10.1016\/j.vaccine.2005.04.017_bib17","series-title":"The anthrax vaccine","first-page":"180","article-title":"Anthrax vaccine manufacture","author":"Joellenbeck","year":"2002"},{"issue":"8","key":"10.1016\/j.vaccine.2005.04.017_bib18","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/0264-410X(91)90237-Z","article-title":"Anthrax vaccines: past, present and future","volume":"9","author":"Turnbull","year":"1991","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2005.04.017_bib19","series-title":"Annapolis MD, Proceedings of the Fourth International Conference on Anthrax","article-title":"Preparation of a freeze-dried anthrax vaccine reference standard for use in the guinea pig potency test","author":"Rijpkema","year":"2001"},{"key":"10.1016\/j.vaccine.2005.04.017_bib20","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1006\/biol.1998.0145","article-title":"Single radial immuno-diffusion as a method for the assay of the acellular pertussis vaccine components, pertussis toxoid, filamentous haemagglutinin and pertactin","volume":"26","author":"Xing DKL","year":"1998","journal-title":"Biologicals"},{"key":"10.1016\/j.vaccine.2005.04.017_bib21","article-title":"Program ELISA for Windows User's Manual, version 1.00. Centers for Disease Control and Prevention","author":"Plikaytis","year":"1996","journal-title":"Atlanta GA"},{"issue":"31\u201332","key":"10.1016\/j.vaccine.2005.04.017_bib22","doi-asserted-by":"crossref","first-page":"4245","DOI":"10.1016\/j.vaccine.2004.04.036","article-title":"Characterisation of adsorbed anthrax vaccine by two-dimensional gel electrophoresis","volume":"22","author":"Whiting","year":"2004","journal-title":"Vaccine"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X05004573?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X05004573?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T08:54:29Z","timestamp":1586249669000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X05004573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8]]},"references-count":22,"journal-issue":{"issue":"36","published-print":{"date-parts":[[2005,8]]}},"alternative-id":["S0264410X05004573"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2005.04.017","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,8]]}}}