{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T15:26:16Z","timestamp":1770996376609,"version":"3.50.1"},"reference-count":62,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.vaccine.2005.08.056","type":"journal-article","created":{"date-parts":[[2005,8,27]],"date-time":"2005-08-27T11:08:27Z","timestamp":1125140907000},"page":"662-670","source":"Crossref","is-referenced-by-count":35,"title":["N-fragment of edema factor as a candidate antigen for immunization against anthrax"],"prefix":"10.1016","volume":"24","author":[{"given":"Mingtao","family":"Zeng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingfu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric D.","family":"Hesek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael E.","family":"Pichichero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2005.08.056_bib1","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1146\/annurev.micro.55.1.647","volume":"55","author":"Mock","year":"2001","journal-title":"Annu Rev Microbiol"},{"issue":"5\u20136","key":"10.1016\/j.vaccine.2005.08.056_bib2","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/S0264-410X(01)00387-5","article-title":"Anthrax vaccine: short-term safety experience in humans","volume":"20","author":"Pittman","year":"2001","journal-title":"Vaccine"},{"issue":"11","key":"10.1016\/j.vaccine.2005.08.056_bib3","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1056\/NEJM199909093411107","volume":"341","author":"Dixon","year":"1999","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.vaccine.2005.08.056_bib4","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0882-4010(91)90053-D","article-title":"Plasmid-associated virulence factors of non-toxigenic (pX01-) Bacillus anthracis","volume":"10","author":"Welkos","year":"1991","journal-title":"Microb Pathog"},{"issue":"2","key":"10.1016\/j.vaccine.2005.08.056_bib5","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1046\/j.1365-2672.1999.00881.x","article-title":"The capsule of bacillus anthracis, a review","volume":"87","author":"Ezzell","year":"1999","journal-title":"J Appl Microbiol"},{"issue":"11","key":"10.1016\/j.vaccine.2005.08.056_bib6","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1016\/S0041-0101(01)00161-1","article-title":"Toxins of Bacillus anthracis","volume":"39","author":"Brossier","year":"2001","journal-title":"Toxicon"},{"issue":"3","key":"10.1016\/j.vaccine.2005.08.056_bib7","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0006-2952(02)01455-7","article-title":"Anthrax toxin receptor proteins","volume":"65","author":"Bradley","year":"2003","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.vaccine.2005.08.056_bib8","first-page":"4","article-title":"Crystal structure of a complex between anthrax toxin and its host cell receptor","volume":"4","author":"Santelli","year":"2004","journal-title":"Nature"},{"issue":"6860","key":"10.1016\/j.vaccine.2005.08.056_bib9","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/n35101999","article-title":"Identification of the cellular receptor for anthrax toxin","volume":"414","author":"Bradley","year":"2001","journal-title":"Nature"},{"issue":"9","key":"10.1016\/j.vaccine.2005.08.056_bib10","doi-asserted-by":"crossref","first-page":"5170","DOI":"10.1073\/pnas.0431098100","article-title":"Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor","volume":"100","author":"Scobie","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"issue":"4","key":"10.1016\/j.vaccine.2005.08.056_bib11","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1128\/IAI.67.4.1853-1859.1999","article-title":"Oligomerization of anthrax toxin protective antigen and binding of lethal factor during endocytic uptake into mammalian cells","volume":"67","author":"Singh","year":"1999","journal-title":"Infect Immun"},{"issue":"7","key":"10.1016\/j.vaccine.2005.08.056_bib12","doi-asserted-by":"crossref","first-page":"3447","DOI":"10.1128\/IAI.66.7.3447-3448.1998","article-title":"Study of immunization against anthrax with the purified recombinant protective antigen of Bacillus anthracis","volume":"66","author":"Singh","year":"1998","journal-title":"Infect Immun"},{"issue":"11","key":"10.1016\/j.vaccine.2005.08.056_bib13","doi-asserted-by":"crossref","first-page":"6652","DOI":"10.1073\/pnas.1131930100","article-title":"A fragment of anthrax lethal factor delivers proteins to the cytosol without requiring protective antigen","volume":"100","author":"Kushner","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"issue":"10","key":"10.1016\/j.vaccine.2005.08.056_bib14","doi-asserted-by":"crossref","first-page":"3162","DOI":"10.1073\/pnas.79.10.3162","article-title":"Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells","volume":"79","author":"Leppla","year":"1982","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.vaccine.2005.08.056_bib15","first-page":"445","article-title":"Anthrax toxin","volume":"145","author":"Leppla","year":"2000"},{"issue":"4","key":"10.1016\/j.vaccine.2005.08.056_bib16","doi-asserted-by":"crossref","first-page":"727","DOI":"10.4049\/jimmunol.96.4.727","article-title":"Immunologic studies of anthrax","volume":"96","author":"Mahlandt","year":"1966","journal-title":"J Immunol"},{"issue":"Part 6","key":"10.1016\/j.vaccine.2005.08.056_bib17","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1099\/00221287-147-6-1677","article-title":"The role of antibodies to Bacillus anthracis and anthrax toxin components in inhibiting the early stages of infection by anthrax spores","volume":"147","author":"Welkos","year":"2001","journal-title":"Microbiology"},{"key":"10.1016\/j.vaccine.2005.08.056_bib18","unstructured":"Anthrax Vaccine Adsorbed (BioThrax) Product insert. BioPort Corporation, Lansing, Michigan; 2002."},{"issue":"22","key":"10.1016\/j.vaccine.2005.08.056_bib19","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1001\/jama.282.22.2104","article-title":"Anthrax vaccine: evidence for safety and efficacy against inhalational anthrax","volume":"282","author":"Friedlander","year":"1999","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.vaccine.2005.08.056_bib20","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1128\/IAI.60.2.662-668.1992","article-title":"Immunization against anthrax with Bacillus anthracis protective antigen combined with adjuvants","volume":"60","author":"Ivins","year":"1992","journal-title":"Infect Immun"},{"issue":"2","key":"10.1016\/j.vaccine.2005.08.056_bib21","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1128\/IAI.72.2.1181-1183.2004","article-title":"Needle-free skin patch vaccination method for anthrax","volume":"72","author":"Matyas","year":"2004","journal-title":"Infect Immun"},{"issue":"4","key":"10.1016\/j.vaccine.2005.08.056_bib22","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1086\/422694","article-title":"Induction of protective immunity against lethal anthrax challenge with a patch","volume":"190","author":"Kenney","year":"2004","journal-title":"J Infect Dis"},{"issue":"19","key":"10.1016\/j.vaccine.2005.08.056_bib23","doi-asserted-by":"crossref","first-page":"10925","DOI":"10.1073\/pnas.1834478100","article-title":"A dually active anthrax vaccine that confers protection against both bacilli and toxins","volume":"100","author":"Rhie","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"10.1016\/j.vaccine.2005.08.056_bib24","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.vaccine.2004.05.029","article-title":"Anthrax capsule vaccine protects against experimental infection","volume":"23","author":"Chabot","year":"2004","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.vaccine.2005.08.056_bib25","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1128\/IAI.70.3.1653-1656.2002","article-title":"A recombinant carboxy-terminal domain of the protective antigen of Bacillus anthracis protects mice against anthrax infection","volume":"70","author":"Flick-Smith","year":"2002","journal-title":"Infect Immun"},{"issue":"4","key":"10.1016\/j.vaccine.2005.08.056_bib26","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/S0264-410X(98)00210-2","article-title":"Protection against anthrax toxin by vaccination with a DNA plasmid encoding anthrax protective antigen","volume":"17","author":"Gu","year":"1999","journal-title":"Vaccine"},{"issue":"25\u201326","key":"10.1016\/j.vaccine.2005.08.056_bib27","doi-asserted-by":"crossref","first-page":"4071","DOI":"10.1016\/S0264-410X(03)00362-1","article-title":"Comparison of individual and combination DNA vaccines for B. anthracis, Ebola virus, Marburg virus and Venezuelan equine encephalitis virus","volume":"21","author":"Riemenschneider","year":"2003","journal-title":"Vaccine"},{"issue":"17","key":"10.1016\/j.vaccine.2005.08.056_bib28","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1089\/104303403322542310","article-title":"Protective immunity evoked against anthrax lethal toxin after a single intramuscular administration of an adenovirus-based vaccine encoding humanized protective antigen","volume":"14","author":"Tan","year":"2003","journal-title":"Hum Gene Ther"},{"issue":"7","key":"10.1016\/j.vaccine.2005.08.056_bib29","doi-asserted-by":"crossref","first-page":"3831","DOI":"10.1128\/IAI.71.7.3831-3836.2003","article-title":"Salmonella enterica serovar typhimurium expressing a chromosomally integrated copy of the Bacillus anthracis protective antigen gene protects mice against an anthrax spore challenge","volume":"71","author":"Garmory","year":"2003","journal-title":"Infect Immun"},{"issue":"15","key":"10.1016\/j.vaccine.2005.08.056_bib30","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1016\/0264-410X(94)90148-1","article-title":"Bacillus anthracis protective antigen, expressed in Salmonella typhimurium SL 3261, affords protection against anthrax spore challenge","volume":"12","author":"Coulson","year":"1994","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.vaccine.2005.08.056_bib31","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1128\/IAI.54.2.537-542.1986","article-title":"Cloning and expression of the Bacillus anthracis protective antigen gene in Bacillus subtilis","volume":"54","author":"Ivins","year":"1986","journal-title":"Infect Immun"},{"issue":"6","key":"10.1016\/j.vaccine.2005.08.056_bib32","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1128\/IAI.59.6.1961-1965.1991","article-title":"Protection against anthrax with recombinant virus-expressed protective antigen in experimental animals","volume":"59","author":"Iacono-Connors","year":"1991","journal-title":"Infect Immun"},{"issue":"3","key":"10.1016\/j.vaccine.2005.08.056_bib33","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1128\/IAI.71.3.1491-1496.2003","article-title":"Venezuelan equine encephalitis virus-vectored vaccines protect mice against anthrax spore challenge","volume":"71","author":"Lee","year":"2003","journal-title":"Infect Immun"},{"issue":"Part 3","key":"10.1016\/j.vaccine.2005.08.056_bib34","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1099\/13500872-142-3-707","article-title":"Characterization of lethal factor binding and cell receptor binding domains of protective antigen of Bacillus anthracis using monoclonal antibodies","volume":"142","author":"Little","year":"1996","journal-title":"Microbiology"},{"issue":"7","key":"10.1016\/j.vaccine.2005.08.056_bib35","doi-asserted-by":"crossref","first-page":"4509","DOI":"10.1128\/IAI.69.7.4509-4515.2001","article-title":"Protection against anthrax lethal toxin challenge by genetic immunization with a plasmid encoding the lethal factor protein","volume":"69","author":"Price","year":"2001","journal-title":"Infect Immun"},{"issue":"13\u201314","key":"10.1016\/j.vaccine.2005.08.056_bib36","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1016\/j.vaccine.2003.09.043","article-title":"Genetic immunization against anthrax","volume":"22","author":"Galloway","year":"2004","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.vaccine.2005.08.056_bib37","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1128\/IAI.56.2.349-356.1988","article-title":"Immunological analysis of cell-associated antigens of Bacillus anthracis","volume":"56","author":"Ezzell","year":"1988","journal-title":"Infect Immun"},{"issue":"2","key":"10.1016\/j.vaccine.2005.08.056_bib38","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1128\/IAI.52.2.356-363.1986","article-title":"Development of antibodies to protective antigen and lethal factor components of anthrax toxin in humans and guinea pigs and their relevance to protective immunity","volume":"52","author":"Turnbull","year":"1986","journal-title":"Infect Immun"},{"issue":"5","key":"10.1016\/j.vaccine.2005.08.056_bib39","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/BF00189414","article-title":"Antibodies to anthrax toxin in humans and guinea pigs and their relevance to protective immunity","volume":"177","author":"Turnbull","year":"1988","journal-title":"Med Microbiol Immunol (Berl)"},{"issue":"2","key":"10.1016\/j.vaccine.2005.08.056_bib40","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0882-4010(88)90015-0","article-title":"Comparative safety and efficacy against Bacillus anthracis of protective antigen and live vaccines in mice","volume":"5","author":"Welkos","year":"1988","journal-title":"Microb Pathog"},{"issue":"5","key":"10.1016\/j.vaccine.2005.08.056_bib41","doi-asserted-by":"crossref","first-page":"2888","DOI":"10.1128\/IAI.69.5.2888-2893.2001","article-title":"Search for correlates of protective immunity conferred by anthrax vaccine","volume":"69","author":"Reuveny","year":"2001","journal-title":"Infect Immun"},{"issue":"4","key":"10.1016\/j.vaccine.2005.08.056_bib42","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1128\/IAI.63.4.1369-1372.1995","article-title":"Protective immunity induced by Bacillus anthracis toxin-deficient strains","volume":"63","author":"Pezard","year":"1995","journal-title":"Infect Immun"},{"issue":"8","key":"10.1016\/j.vaccine.2005.08.056_bib43","doi-asserted-by":"crossref","first-page":"4549","DOI":"10.1128\/IAI.68.8.4549-4558.2000","article-title":"Attenuated nontoxinogenic and nonencapsulated recombinant Bacillus anthracis spore vaccines protect against anthrax","volume":"68","author":"Cohen","year":"2000","journal-title":"Infect Immun"},{"issue":"5","key":"10.1016\/j.vaccine.2005.08.056_bib44","doi-asserted-by":"crossref","first-page":"3334","DOI":"10.1016\/S0021-9258(18)53698-X","article-title":"Residues 1\u2013254 of anthrax toxin lethal factor are sufficient to cause cellular uptake of fused polypeptides","volume":"268","author":"Arora","year":"1993","journal-title":"J Biol Chem"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2005.08.056_bib45","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1023\/A:1006815306876","article-title":"Site directed mutagenesis of histidine residues in anthrax toxin lethal factor binding domain reduces toxicity","volume":"177","author":"Arora","year":"1997","journal-title":"Mol Cell Biochem"},{"issue":"1","key":"10.1016\/j.vaccine.2005.08.056_bib46","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1006\/bbrc.2000.4099","article-title":"Involvement of residues 147VYYEIGK153 in binding of lethal factor to protective antigen of Bacillus anthracis","volume":"280","author":"Gupta","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"issue":"6860","key":"10.1016\/j.vaccine.2005.08.056_bib47","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/n35101998","article-title":"Crystal structure of the anthrax lethal factor","volume":"414","author":"Pannifer","year":"2001","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.vaccine.2005.08.056_bib48","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1006\/bbrc.1994.1281","article-title":"Structure-function analysis of Bacillus anthracis edema factor by using monoclonal antibodies","volume":"199","author":"Little","year":"1994","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.vaccine.2005.08.056_bib49","first-page":"286","article-title":"New perspectives in adenoviruses","volume":"18","author":"Lukashok","year":"1998","journal-title":"Curr Clin Topics Infect Dis"},{"issue":"23","key":"10.1016\/j.vaccine.2005.08.056_bib50","doi-asserted-by":"crossref","first-page":"11474","DOI":"10.1128\/JVI.75.23.11474-11482.2001","article-title":"Protection against tetanus by needle-free inoculation of adenovirus-vectored nasal and epicutaneous vaccines","volume":"75","author":"Shi","year":"2001","journal-title":"J Virol"},{"issue":"6","key":"10.1016\/j.vaccine.2005.08.056_bib51","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/nm0697-651","article-title":"Long-term protection of chimpanzees against high-dose HIV-1 challenge induced by immunization","volume":"3","author":"Lubeck","year":"1997","journal-title":"Nat Med"},{"key":"10.1016\/j.vaccine.2005.08.056_bib52","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/415331a","article-title":"Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity","volume":"415","author":"Shiver","year":"2002","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.vaccine.2005.08.056_bib53","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0378-1119(88)90501-X","article-title":"Nucleotide sequence of the Bacillus anthracis edema factor gene (cya): a calmodulin-dependent adenylate cyclase","volume":"73","author":"Robertson","year":"1988","journal-title":"Gene"},{"issue":"3","key":"10.1016\/j.vaccine.2005.08.056_bib54","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1128\/IAI.51.3.795-800.1986","article-title":"Differences in susceptibility of inbred mice to Bacillus anthracis","volume":"51","author":"Welkos","year":"1986","journal-title":"Infect Immun"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2005.08.056_bib55","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jim.2004.12.022","article-title":"Development of an edema factor-mediated cAMP-induction bioassay for detecting antibody-mediated neutralization of anthrax protective antigen","volume":"298","author":"Zmuda","year":"2005","journal-title":"J Immunol Methods"},{"issue":"6","key":"10.1016\/j.vaccine.2005.08.056_bib56","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1128\/IAI.58.6.1606-1613.1990","article-title":"Production and characterization of monoclonal antibodies against the lethal factor component of Bacillus anthracis lethal toxin","volume":"58","author":"Little","year":"1990","journal-title":"Infect Immun"},{"issue":"3","key":"10.1016\/j.vaccine.2005.08.056_bib57","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S1046-2023(03)00134-8","article-title":"Technical issues in construction of nucleic acid vaccines","volume":"31","author":"Ertl","year":"2003","journal-title":"Methods"},{"issue":"37","key":"10.1016\/j.vaccine.2005.08.056_bib58","doi-asserted-by":"crossref","first-page":"13601","DOI":"10.1073\/pnas.0405557101","article-title":"A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores","volume":"101","author":"Hermanson","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"issue":"15","key":"10.1016\/j.vaccine.2005.08.056_bib59","doi-asserted-by":"crossref","first-page":"8263","DOI":"10.1128\/JVI.77.15.8263-8271.2003","article-title":"Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity","volume":"77","author":"Vogels","year":"2003","journal-title":"J Virol"},{"issue":"4","key":"10.1016\/j.vaccine.2005.08.056_bib60","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/sj.gt.3301903","article-title":"Development of an Ad7 cosmid system and generation of an Ad7deltaE1deltaE3HIV(MN) env\/rev recombinant virus","volume":"10","author":"Nan","year":"2003","journal-title":"Gene Ther"},{"issue":"8","key":"10.1016\/j.vaccine.2005.08.056_bib61","doi-asserted-by":"crossref","first-page":"6930","DOI":"10.1128\/JVI.73.8.6930-6936.1999","article-title":"Ovine adenovirus vectors overcome preexisting humoral immunity against human adenoviruses in vivo","volume":"73","author":"Hofmann","year":"1999","journal-title":"J Virol"},{"issue":"23","key":"10.1016\/j.vaccine.2005.08.056_bib62","doi-asserted-by":"crossref","first-page":"11603","DOI":"10.1128\/JVI.75.23.11603-11613.2001","article-title":"Replication-defective vector based on a chimpanzee adenovirus","volume":"75","author":"Farina","year":"2001","journal-title":"J Virol"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X05008716?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X05008716?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T09:16:28Z","timestamp":1683191788000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X05008716"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":62,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S0264410X05008716"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2005.08.056","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}