{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T12:34:11Z","timestamp":1789907651941,"version":"4.0.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"21","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.vaccine.2007.02.075","type":"journal-article","created":{"date-parts":[[2007,3,16]],"date-time":"2007-03-16T07:01:31Z","timestamp":1174028491000},"page":"4244-4251","source":"Crossref","is-referenced-by-count":50,"title":["Safety review of the purified chick embryo cell rabies vaccine: Data from the Vaccine Adverse Event Reporting System (VAERS), 1997\u20132005"],"prefix":"10.1016","volume":"25","author":[{"given":"Azra","family":"Dobardzic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector","family":"Izurieta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily Jane","family":"Woo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Iskander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Shadomy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Rupprecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Ball","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Miles Braun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2007.02.075_bib1","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0091-6749(87)80278-6","article-title":"The role of specific IgE and b-propiolactone in reactions resulting from booster doses of human diploid cell rabies vaccine","volume":"80","author":"Anderson","year":"1987","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.vaccine.2007.02.075_bib2","unstructured":"Centers for Disease Control. Systemic allergic reactions following immunization with human diploid cell rabies vaccine. MMWR 1984; 33:185\u20138."},{"key":"10.1016\/j.vaccine.2007.02.075_bib3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0264-410X(86)90096-4","article-title":"Immune complex-like disease in 23 persons following a booster dose of rabies human diploid cell vaccine","volume":"4","author":"Dreesen","year":"1986","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2007.02.075_bib4","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/0264-410X(87)90102-2","article-title":"Preexposure studies with purified chick embryo cell culture rabies vaccine and human diploid cell vaccine: serological and clinical responses in man","volume":"5","author":"Nicholson","year":"1987","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2007.02.075_bib5","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/0264-410X(89)90152-7","article-title":"Two-year comparative trial on the immunogenicity and adverse effects of purified chick embryo cell rabies vaccine for preexposure immunization","volume":"7","author":"Dreesen","year":"1989","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2007.02.075_bib6","first-page":"99","article-title":"Preexposure vaccination with purified chick embryo cell rabies vaccines in children","volume":"7","author":"Lumbiganon","year":"1989","journal-title":"Asian Pacific J Allergy Immunol"},{"key":"10.1016\/j.vaccine.2007.02.075_bib7","first-page":"36","article-title":"Ten year longitudinal study of efficacy and safety of purified chick embryo cell vaccine for pre- and postexposure prophylaxis of rabies in Indian population","volume":"27","author":"Sehgal","year":"1995","journal-title":"J Commun Dis"},{"key":"10.1016\/j.vaccine.2007.02.075_bib8","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0140-6736(90)91861-4","article-title":"Survival after rabies immunisation in newborn infant of affected mother","volume":"336","author":"Lumbiganon","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.vaccine.2007.02.075_bib9","first-page":"61","article-title":"Clinical trials in healthy volunteers with the new purified chick embryo cell rabies vaccine for man","volume":"16","author":"Bijok","year":"1984","journal-title":"J Commun Dis"},{"key":"10.1016\/j.vaccine.2007.02.075_bib10","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1471-2415-5-20","article-title":"Bilateral neuro-retinitis following chick embryo cell anti-rabies vaccination\u2014a case report","volume":"5","author":"Saxena","year":"2005","journal-title":"BMC Ophthalmol"},{"key":"10.1016\/j.vaccine.2007.02.075_bib11","first-page":"927","article-title":"Neurologic illness following post-exposure prophylaxis with purifiled chick embryo cell antirabies vaccine","volume":"49","author":"Chakravarty","year":"2001","journal-title":"J Assoc Physicians India"},{"key":"10.1016\/j.vaccine.2007.02.075_bib12","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.tree.2005.02.009","article-title":"Emerging pathogens: the epidemiology and evolution of species jumps","volume":"20","author":"Woolhouse","year":"2005","journal-title":"Trends Ecol Evol"},{"key":"10.1016\/j.vaccine.2007.02.075_bib13","unstructured":"PCEC. Rabies vaccine for human use. Product label. Chiron Behring GmbH & Co KG. In: Physician desk zerence. 59th ed. Montvale, NJ: Thomson PDR, 2005:1140\u20131143."},{"key":"10.1016\/j.vaccine.2007.02.075_bib14","unstructured":"Human rabies prevention\u2013United States, 1999. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm. Rep. 1999 Jan 8; 48(RR-1):1\u201321."},{"key":"10.1016\/j.vaccine.2007.02.075_bib15","unstructured":"The US Food and Drug Administration (FDA). COSTART coding symbols for thesaurus of adverse reaction terms. Rockville, MD: Public Health Service, FDA, 1995."},{"issue":"4","key":"10.1016\/j.vaccine.2007.02.075_bib16","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1097\/00006454-200404000-00002","article-title":"Understanding vaccine safety information from the Vaccine Adverse Event Reporting System","volume":"23","author":"Varricchio","year":"2004","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.vaccine.2007.02.075_bib17","first-page":"10","article-title":"The complicated task of monitoring vaccine safety","volume":"112","author":"Ellenberg","year":"1997","journal-title":"Public Health Rep"},{"key":"10.1016\/j.vaccine.2007.02.075_bib18","unstructured":"Postmarketing reporting of adverse experiences (21 CFR Part 600.80). National Archives and Records Administration, Code of Federal Regulations Web site. 1999. Available at: JOC50142.doc (sbenner) http:\/\/www.access.gpo.gov\/nara\/cfr\/waisidx_99\/21cfr600_99.html. Accessibility verified October 18, 2005."},{"key":"10.1016\/j.vaccine.2007.02.075_bib19","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1542\/peds.112.4.815","article-title":"Risk of anaphylaxis after vaccination of children and adolescents","volume":"112","author":"Bohlke","year":"2003","journal-title":"Pediatrics"},{"key":"10.1016\/j.vaccine.2007.02.075_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/pds.1107","article-title":"Comparing data mining methods on the VAERS database","volume":"14","author":"Banks","year":"2005","journal-title":"Pharmacoepidemiol Drug Safety"},{"issue":"5","key":"10.1016\/j.vaccine.2007.02.075_bib21","doi-asserted-by":"crossref","first-page":"375","DOI":"10.2165\/00002018-200629050-00002","article-title":"The VAERS Team. Data mining in the US using the Vaccine Adverse Event Reporting System","volume":"29","author":"Iskander","year":"2006","journal-title":"Drug Safety"},{"key":"10.1016\/j.vaccine.2007.02.075_bib22","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/pds.677","article-title":"Use of proportional reporting ratios (PRRs) for signal generation from spontaneous adverse drug reaction reports","volume":"10","author":"Evans","year":"2001","journal-title":"Pharmacoepidemiol Drug Safety"},{"key":"10.1016\/j.vaccine.2007.02.075_bib23","unstructured":"Zhou W, Pool V, Iskander JK, English-Bullard R, Ball R, Wise RP, et al. Surveillance for Safety After Immunization: Vaccine Adverse Event Reporting System (VAERS)\u2014United States, 1991\u20132001. In: Surveillance Summaries, January 24, 2003. MMWR 2003; 52(SS-1): 1\u201324."},{"key":"10.1016\/j.vaccine.2007.02.075_bib24","unstructured":"Centers for Disease Control and Prevention Injury Prevention Center: July 2002. Available at: http:\/\/www.cdc.gov\/ncipc\/fact_book\/14_Dog_Bite_Injuries.htm."},{"key":"10.1016\/j.vaccine.2007.02.075_bib25","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/S0033-3182(85)72867-8","article-title":"Observations on misdiagnosis of rabies","volume":"26","author":"Schneider","year":"1985","journal-title":"Psychosomatics"},{"key":"10.1016\/j.vaccine.2007.02.075_bib26","unstructured":"Human Rabies\u2014Texas and New Jersey, 1997. MMWR Morb Mortal Wkly Rep 1998;47:1\u20135."},{"key":"10.1016\/j.vaccine.2007.02.075_bib27","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/0895-4356(91)90147-2","article-title":"Epidemiology of headache in a general population\u2014a prevalence study","volume":"44","author":"Rasmussen","year":"1991","journal-title":"J Clin Epidemiol"},{"issue":"6","key":"10.1016\/j.vaccine.2007.02.075_bib28","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1542\/peds.110.6.e71","article-title":"Prevalence of anti-gelatin IgE antibodies in people with anaphylaxis after measles\u2013mumps\u2013rubella vaccine in the United States","volume":"110","author":"Pool","year":"2002","journal-title":"Pediatrics"},{"key":"10.1016\/j.vaccine.2007.02.075_bib29","unstructured":"Systemic allergic reactions following immunization with human diploid cell rabies vaccine. MMWR 1984; 33:185\u20137."},{"key":"10.1016\/j.vaccine.2007.02.075_bib30","unstructured":"CDC. General Recommendations on Immunization. Recommendations of the Advisory Committee on Immunization Practices (ACIP) and the American Academy of Family Physicians (AAFP). MMWR 2002; 51(No. RR02):1\u201336."},{"key":"10.1016\/j.vaccine.2007.02.075_bib31","unstructured":"American Academy of Pediatrics. Active and Passive Immunization. In: Pickering LK, Ed. Red Book: 2003 Report of the Committee on Infectious Diseases. 26th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2003:17."},{"key":"10.1016\/j.vaccine.2007.02.075_bib32","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1001\/archpedi.1997.02170400041007","article-title":"Syncope after immunization","volume":"151","author":"Braun","year":"1997","journal-title":"Arch Pediatr Adolesc Med"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X07002769?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X07002769?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,8]],"date-time":"2019-01-08T14:25:29Z","timestamp":1546957529000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X07002769"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":32,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S0264410X07002769"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2007.02.075","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}