{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T11:44:49Z","timestamp":1775303089223,"version":"3.50.1"},"reference-count":57,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.vaccine.2008.10.034","type":"journal-article","created":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T08:44:43Z","timestamp":1225529083000},"page":"28-37","source":"Crossref","is-referenced-by-count":45,"title":["Protection against tuberculosis induced by oral prime with Mycobacterium bovis BCG and intranasal subunit boost based on the vaccine candidate Ag85B-ESAT-6 does not correlate with circulating IFN-\u03b3 producing T-cells"],"prefix":"10.1016","volume":"27","author":[{"given":"Edgar","family":"Badell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabienne","family":"Nicolle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Clark","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laleh","family":"Majlessi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Boudou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Martino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz","family":"Castello-Branco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claude","family":"Leclerc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.M.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip D.","family":"Marsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brigitte","family":"Gicquel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Winter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9517","key":"10.1016\/j.vaccine.2008.10.034_bib1","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/S0140-6736(06)68507-3","article-title":"Effect of BCG vaccination on childhood tuberculous meningitis and miliary tuberculosis worldwide: a meta-analysis and assessment of cost-effectiveness","volume":"367","author":"Trunz-Bourdin","year":"2006","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.vaccine.2008.10.034_bib2","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1080\/003655401300077144","article-title":"BCG: the challenge continues","volume":"33","author":"Fine","year":"2001","journal-title":"Scand J Infect Dis"},{"issue":"21","key":"10.1016\/j.vaccine.2008.10.034_bib3","doi-asserted-by":"crossref","first-page":"2740","DOI":"10.1016\/j.vaccine.2004.11.051","article-title":"Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6","volume":"23","author":"Langermans","year":"2005","journal-title":"Vaccine"},{"issue":"9","key":"10.1016\/j.vaccine.2008.10.034_bib4","doi-asserted-by":"crossref","first-page":"4901","DOI":"10.1128\/IAI.71.9.4901-4907.2003","article-title":"A DNA prime-Mycobacterium bovis BCG boost vaccination strategy for cattle induces protection against bovine tuberculosis","volume":"71","author":"Skinner","year":"2003","journal-title":"Infect Immun"},{"issue":"9","key":"10.1016\/j.vaccine.2008.10.034_bib5","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1038\/nri1920","article-title":"Envisioning future strategies for vaccination against tuberculosis","volume":"6","author":"Kaufmann","year":"2006","journal-title":"Nat Rev Immunol"},{"issue":"9","key":"10.1016\/j.vaccine.2008.10.034_bib6","doi-asserted-by":"crossref","first-page":"6353","DOI":"10.4049\/jimmunol.177.9.6353","article-title":"Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior Bacillus Calmette\u2013Guerin immunity","volume":"177","author":"Dietrich","year":"2006","journal-title":"J Immunol"},{"issue":"28","key":"10.1016\/j.vaccine.2008.10.034_bib7","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.1016\/S0264-410X(00)00134-1","article-title":"Intranasal vaccination of mice against infection with Mycobacterium tuberculosis","volume":"18","author":"Falero-Diaz","year":"2000","journal-title":"Vaccine"},{"issue":"12","key":"10.1016\/j.vaccine.2008.10.034_bib8","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1038\/nri1728","article-title":"Immunization without needles","volume":"5","author":"Mitragotri","year":"2005","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.vaccine.2008.10.034_bib9","first-page":"89","article-title":"Pr\u00e9munition des nouveau-n\u00e9s contre la tuberculose par le vaccin BCG","volume":"2","author":"Calmette","year":"1926","journal-title":"Ann Inst Pasteur"},{"issue":"5","key":"10.1016\/j.vaccine.2008.10.034_bib10","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1590\/S0074-02762005000500002","article-title":"BCG Rio de Janeiro: an oral vaccine against tuberculosis","volume":"100","author":"Benevolo-de-Andreade","year":"2005","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"4","key":"10.1016\/j.vaccine.2008.10.034_bib11","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1128\/IAI.74.4.2449-2452.2006","article-title":"Boosting of cellular immunity against Mycobacterium tuberculosis and modulation of skin cytokine responses in healthy human volunteers by Mycobacterium bovis BCG substrain Moreau Rio de Janeiro oral vaccine","volume":"74","author":"Cosgrove","year":"2006","journal-title":"Infect Immun"},{"issue":"2","key":"10.1016\/j.vaccine.2008.10.034_bib12","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1365-3083.1988.tb02338.x","article-title":"Specific lymphoproliferation, gamma interferon production, and serum immunoglobulin G directed against a purified 32kDa mycobacterial protein antigen (P32) in patients with active tuberculosis","volume":"27","author":"Huygen","year":"1988","journal-title":"Scand J Immunol"},{"issue":"6","key":"10.1016\/j.vaccine.2008.10.034_bib13","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1002\/1521-4141(200006)30:6<1724::AID-IMMU1724>3.0.CO;2-A","article-title":"Efficient protection against Mycobacterium tuberculosis by vaccination with a single subdominant epitope from the ESAT-6 antigen","volume":"30","author":"Olsen","year":"2000","journal-title":"Eur J Immunol"},{"issue":"12","key":"10.1016\/j.vaccine.2008.10.034_bib14","doi-asserted-by":"crossref","first-page":"7618","DOI":"10.4049\/jimmunol.172.12.7618","article-title":"Differential immune response and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mt72F, delivered as naked DNA or recombinant protein","volume":"172","author":"Skeiky","year":"2004","journal-title":"J Immunol"},{"issue":"5","key":"10.1016\/j.vaccine.2008.10.034_bib15","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1046\/j.1365-3083.1998.00419.x","article-title":"Comparison of antigen-specific T-cell responses of tuberculosis patients using complex or single antigens of Mycobacterium tuberculosis","volume":"48","author":"Mustafa","year":"1998","journal-title":"Scand J Immunol"},{"issue":"5419","key":"10.1016\/j.vaccine.2008.10.034_bib16","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1126\/science.284.5419.1520","article-title":"Comparative genomics of BCG vaccines by whole-genome DNA microarray","volume":"284","author":"Behr","year":"1999","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.vaccine.2008.10.034_bib17","doi-asserted-by":"crossref","first-page":"2773","DOI":"10.1128\/IAI.69.5.2773-2778.2001","article-title":"Protection of mice with a tuberculosis subunit vaccine based on a fusion protein of Antigen 85B and ESAT-6","volume":"69","author":"Olsen","year":"2001","journal-title":"Infect Immun"},{"issue":"10","key":"10.1016\/j.vaccine.2008.10.034_bib18","doi-asserted-by":"crossref","first-page":"6148","DOI":"10.1128\/IAI.72.10.6148-6150.2004","article-title":"Protective effect of a tuberculosis subunit vaccine based on a fusion of antigen 85B and ESAT-6 in the aerosol guinea pig model","volume":"72","author":"Olsen","year":"2004","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.vaccine.2008.10.034_bib19","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/0092-1157(88)90025-X","article-title":"The stability and immunogenicity of a dispersed grown freeze-dried Pasteur BCG vaccine","volume":"16","author":"Gheorghiu","year":"1988","journal-title":"J Biol Stand"},{"issue":"6326","key":"10.1016\/j.vaccine.2008.10.034_bib20","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/351456a0","article-title":"New use of BCG for recombinant vaccines","volume":"351","author":"Stover","year":"1991","journal-title":"Nature"},{"issue":"12","key":"10.1016\/j.vaccine.2008.10.034_bib21","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1086\/425931","article-title":"Comparative analysis of different vaccine constructs expressing defined antigens from Mycobacterium tuberculosis","volume":"190","author":"Doherty","year":"2004","journal-title":"J Infect Dis"},{"issue":"2","key":"10.1016\/j.vaccine.2008.10.034_bib22","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1099\/00221287-144-2-577","article-title":"Extracellular enzyme activities potentially involved in the pathogenicity of Mycobacterium tuberculosis","volume":"144","author":"Raynaud","year":"1998","journal-title":"Microbiology"},{"issue":"2","key":"10.1016\/j.vaccine.2008.10.034_bib23","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1128\/IAI.62.2.363-370.1994","article-title":"Mapping of TH1 helper T-cell epitopes on major secreted mycobacterial antigen 85A in mice infected with live Mycobacterium bovis BCG","volume":"62","author":"Huygen","year":"1994","journal-title":"Infect Immun"},{"issue":"7","key":"10.1016\/j.vaccine.2008.10.034_bib24","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1084\/jem.187.7.1123","article-title":"Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity","volume":"187","author":"Giuliani","year":"1998","journal-title":"J Exp Med"},{"issue":"12","key":"10.1016\/j.vaccine.2008.10.034_bib25","doi-asserted-by":"crossref","first-page":"7094","DOI":"10.1128\/IAI.68.12.7094-7099.2000","article-title":"Identification of a Mycobacterium bovis BCG auxotrophic mutant that protects guinea pigs against M. bovis and hematogenous spread of Mycobacterium tuberculosis without sensitization to tuberculin","volume":"68","author":"Chambers","year":"2000","journal-title":"Infect Immun"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2008.10.034_bib26","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.tube.2004.09.009","article-title":"Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis","volume":"85","author":"Williams","year":"2005","journal-title":"Tuberculosis"},{"issue":"3","key":"10.1016\/j.vaccine.2008.10.034_bib27","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1046\/j.1365-2672.2000.00807.x","article-title":"Survival of mycobacterial species in aerosols generated from artificial saliva","volume":"31","author":"Lever","year":"2000","journal-title":"Lett Appl Microbiol"},{"issue":"3","key":"10.1016\/j.vaccine.2008.10.034_bib28","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0378-1135(00)00378-3","article-title":"A guinea pig model of low-dose Mycobacterium bovis aerogenic infection","volume":"80","author":"Chambers","year":"2001","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.vaccine.2008.10.034_bib29","doi-asserted-by":"crossref","first-page":"e33","DOI":"10.1371\/journal.ppat.0040033","article-title":"Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP","volume":"4","author":"Frigui","year":"2008","journal-title":"PloS Pathog"},{"issue":"4","key":"10.1016\/j.vaccine.2008.10.034_bib30","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1128\/IAI.74.4.2128-2137.2006","article-title":"An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis","volume":"74","author":"Majlessi","year":"2006","journal-title":"Infect Immun"},{"issue":"7","key":"10.1016\/j.vaccine.2008.10.034_bib31","doi-asserted-by":"crossref","first-page":"4295","DOI":"10.1128\/IAI.69.7.4295-4302.2001","article-title":"Subcellular localization of the intracellular survival-enhancing Eis protein of Mycobacterium tuberculosis","volume":"69","author":"Dahl","year":"2001","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.vaccine.2008.10.034_bib32","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1128\/IAI.70.1.303-314.2002","article-title":"Plasmidic versus insertional cloning of heterologous genes in Mycobacterium bovis BCG: impact on in vivo antigen persistence and immune responses","volume":"70","author":"M\u00e9derl\u00e9","year":"2002","journal-title":"Infect Immun"},{"issue":"8","key":"10.1016\/j.vaccine.2008.10.034_bib33","doi-asserted-by":"crossref","first-page":"3527","DOI":"10.4049\/jimmunol.157.8.3527","article-title":"Key epitopes on the ESAT-6 antigen recognized in mice during the recall of protective immunity to Mycobacterium tuberculosis","volume":"157","author":"Brandt","year":"1996","journal-title":"J Immunol"},{"issue":"10","key":"10.1016\/j.vaccine.2008.10.034_bib34","doi-asserted-by":"crossref","first-page":"4962","DOI":"10.1128\/JVI.80.10.4962-4970.2006","article-title":"Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers","volume":"80","author":"Stephenson","year":"2006","journal-title":"J Virol"},{"issue":"2","key":"10.1016\/j.vaccine.2008.10.034_bib35","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1128\/IAI.68.2.791-795.2000","article-title":"ESAT-6 subunit vaccination against Mycobacterium tuberculosis","volume":"68","author":"Brandt","year":"2000","journal-title":"Infect Immun"},{"issue":"Suppl. 3","key":"10.1016\/j.vaccine.2008.10.034_bib36","doi-asserted-by":"crossref","first-page":"S279","DOI":"10.1086\/313874","article-title":"Correlates of protective immunity to Mycobacterium tuberculosis in humans","volume":"30","author":"Ellner","year":"2000","journal-title":"Clin Infect Dis"},{"issue":"17\u201319","key":"10.1016\/j.vaccine.2008.10.034_bib37","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1016\/S0264-410X(00)00519-3","article-title":"Tuberculosis subunit vaccine development: on the role of interferon-g","volume":"19","author":"Agger","year":"2001","journal-title":"Vaccine"},{"issue":"10","key":"10.1016\/j.vaccine.2008.10.034_bib38","doi-asserted-by":"crossref","first-page":"6332","DOI":"10.4049\/jimmunol.174.10.6332","article-title":"Exchanging ESAT6 with TB10.4 in an Ag85B fusion molecule-based tuberculosis subunit vaccine: efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy","volume":"174","author":"Dietrich","year":"2005","journal-title":"J Immunol"},{"issue":"1","key":"10.1016\/j.vaccine.2008.10.034_bib39","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1128\/IAI.74.1.88-98.2006","article-title":"Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence","volume":"74","author":"Brodin","year":"2006","journal-title":"Infect Immun"},{"issue":"21","key":"10.1016\/j.vaccine.2008.10.034_bib40","doi-asserted-by":"crossref","first-page":"12420","DOI":"10.1073\/pnas.1635213100","article-title":"The primary mechanism of attenuation of bacillus Calmette\u2013Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue","volume":"100","author":"Hsu","year":"2003","journal-title":"Proc Natl Acad Sci"},{"issue":"6","key":"10.1016\/j.vaccine.2008.10.034_bib41","doi-asserted-by":"crossref","first-page":"3570","DOI":"10.4049\/jimmunol.174.6.3570","article-title":"Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system","volume":"174","author":"Majlessi","year":"2005","journal-title":"J Immunol"},{"issue":"5","key":"10.1016\/j.vaccine.2008.10.034_bib42","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/nm859","article-title":"Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis","volume":"9","author":"Pym","year":"2003","journal-title":"Nat Med"},{"issue":"24","key":"10.1016\/j.vaccine.2008.10.034_bib43","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1016\/S0264-410X(00)00070-0","article-title":"Immune responses induced by recombinant BCG strains according to level of production of a foreign antigen: MalE","volume":"18","author":"Himmelrich","year":"2000","journal-title":"Vaccine"},{"issue":"14","key":"10.1016\/j.vaccine.2008.10.034_bib44","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1016\/j.vaccine.2004.10.007","article-title":"Expanding the antigenic repertoire of BCG improves protective efficacy against aerosol Mycobacterium tuberculosis infection","volume":"23","author":"Palendira","year":"2005","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2008.10.034_bib45","series-title":"Mucosal vaccines","first-page":"269","article-title":"Mucosal immunity induced by oral administration of bacille Calmette\u2013Gu\u00e9rin","author":"Hoft","year":"1996"},{"issue":"1","key":"10.1016\/j.vaccine.2008.10.034_bib46","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0008-8749(84)90082-0","article-title":"Adoptive protection of the Mycobacterium tuberculosis-infected lung. Dissociation between cells that passively transfer protective immunity and those that transfer delayed-type hypersensitivity to tuberculin","volume":"84","author":"Orme","year":"1984","journal-title":"Cell Immunol"},{"issue":"8932","key":"10.1016\/j.vaccine.2008.10.034_bib47","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/S0140-6736(94)90748-X","article-title":"Delayed-type hypersensitivity, mycobacterial vaccines and protective immunity","volume":"344","author":"Fine","year":"1994","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.vaccine.2008.10.034_bib48","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1093\/infdis\/167.6.1481","article-title":"T cell response to Mycobacterium tuberculosis","volume":"167","author":"Orme","year":"1993","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2008.10.034_bib49","first-page":"107","article-title":"BCG complications","volume":"21","author":"Lotte","year":"1984","journal-title":"Adv Tubercl Res"},{"issue":"9","key":"10.1016\/j.vaccine.2008.10.034_bib50","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1056\/NEJMoa030595","article-title":"Use of the inactivated intranasal influenza vaccine and the risk of Bell's palsy in Switzerland","volume":"350","author":"Mutsch","year":"2004","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.vaccine.2008.10.034_bib51","doi-asserted-by":"crossref","first-page":"3111","DOI":"10.1128\/IAI.70.6.3111-3121.2002","article-title":"Oral vaccination with subunit vaccines protects animals against aerosol infection with Mycobacterium tuberculosis","volume":"70","author":"Doherty","year":"2002","journal-title":"Infect Immun"},{"issue":"30","key":"10.1016\/j.vaccine.2008.10.034_bib52","doi-asserted-by":"crossref","first-page":"12434","DOI":"10.1073\/pnas.0703510104","article-title":"Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis","volume":"104","author":"Mittr\u00fccker","year":"2007","journal-title":"Proc Natl Acad Sci"},{"issue":"7","key":"10.1016\/j.vaccine.2008.10.034_bib53","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/nm1592","article-title":"Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major","volume":"13","author":"Darrah","year":"2007","journal-title":"Nat Med"},{"issue":"20","key":"10.1016\/j.vaccine.2008.10.034_bib54","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1016\/j.vaccine.2004.11.032","article-title":"Role of IgA in the defense against respiratory infections: IgA deficient mice exhibited increased susceptibility to intranasal infection with Mycobacterium bovis BCG","volume":"23","author":"Rodriguez","year":"2005","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.vaccine.2008.10.034_bib55","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/j.1365-2567.2004.01809.x","article-title":"Passive protection with immunoglobulin A antibodies against tuberculous early infection in lungs","volume":"111","author":"Williams","year":"2004","journal-title":"Immunology"},{"issue":"6","key":"10.1016\/j.vaccine.2008.10.034_bib56","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1378\/chest.06-2471","article-title":"Diagnosing tuberculosis infection in the 21st century: new tools to tackle an old enemy","volume":"131","author":"Lalvani","year":"2007","journal-title":"Chest"},{"issue":"6","key":"10.1016\/j.vaccine.2008.10.034_bib57","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.1128\/IAI.70.6.3026-3032.2002","article-title":"Correlation of ESAT-6-specific gamma interferon production with pathology in cattle following Mycobacterium bovis BCG vaccination against experimental bovine tuberculosis","volume":"70","author":"Vordermeier","year":"2002","journal-title":"Infect Immun"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X08014230?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X08014230?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T21:14:14Z","timestamp":1684617254000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X08014230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":57,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0264410X08014230"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2008.10.034","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}