{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T21:59:09Z","timestamp":1773871149746,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"27","license":[{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1016\/j.vaccine.2009.03.063","type":"journal-article","created":{"date-parts":[[2009,4,20]],"date-time":"2009-04-20T08:35:43Z","timestamp":1240216543000},"page":"3553-3560","source":"Crossref","is-referenced-by-count":62,"title":["Serotypes and antimicrobial susceptibilities of invasive Streptococcus pneumoniae pre- and post-seven valent pneumococcal conjugate vaccine introduction in Alberta, Canada, 2000\u20132006"],"prefix":"10.1016","volume":"27","author":[{"given":"Gregory J.","family":"Tyrrell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marguerite","family":"Lovgren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Chui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Minion","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sipi","family":"Garg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James D.","family":"Kellner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas J.","family":"Marrie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"Suppl. 1","key":"10.1016\/j.vaccine.2009.03.063_bib1","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1016\/S0264-410X(99)00122-X","article-title":"The burden of pneumococcal disease among adults in developed and developing countries: what is said and is not known","volume":"17","author":"Fedson","year":"1999","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.vaccine.2009.03.063_bib2","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1473-3099(01)00170-0","article-title":"Estimates of world-wide distribution of child deaths from acute respiratory infections","volume":"2","author":"Williams","year":"2002","journal-title":"Lancet Infect Dis"},{"issue":"10","key":"10.1016\/j.vaccine.2009.03.063_bib3","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.1128\/JCM.33.10.2759-2762.1995","article-title":"Six newly recognized types of Streptococcus pneumoniae","volume":"33","author":"Henrichsen","year":"1995","journal-title":"J Clin Microbiol"},{"issue":"4","key":"10.1016\/j.vaccine.2009.03.063_bib4","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1128\/JCM.02199-06","article-title":"Discovery of a new capsular serotype (6C) within serogroup 6 of Streptococcus pneumoniae","volume":"45","author":"Park","year":"2007","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.vaccine.2009.03.063_bib5","series-title":"Canadian immunization guide","author":"National Advisory Committee on Immunization","year":"2006"},{"key":"10.1016\/j.vaccine.2009.03.063_bib6","unstructured":"Alberta Health and Wellness, Health Surveillance. Population Projections for Alberta and its Health Regions, 2000\u20132030. January 2001."},{"key":"10.1016\/j.vaccine.2009.03.063_bib7","unstructured":"Canada Communicable Disease Report. Case definitions for diseases under National Surveillance-Health Canada. May 2000; 26S3:51."},{"key":"10.1016\/j.vaccine.2009.03.063_bib8","series-title":"Manual of clinical microbiology","first-page":"238","article-title":"Streptococcus and related catalase-negative gram-positive cocci","author":"Facklam","year":"1991"},{"key":"10.1016\/j.vaccine.2009.03.063_bib9","first-page":"241","article-title":"Laboratory diagnosis, serology and epidemiology of Streptococcus pneumoniae","volume":"vol. 12","author":"Lund","year":"1978"},{"key":"10.1016\/j.vaccine.2009.03.063_bib10","series-title":"Performance standard for antimicrobial susceptibility testing; fifteenth informational supplement","author":"Clinical and Laboratory Standards Institute","year":"2005"},{"key":"10.1016\/j.vaccine.2009.03.063_bib11","series-title":"Methods for dilution susceptibility testing for bacteria that grow aerobically; approved standard","author":"National Committee for Clinical Laboratory Standards","year":"2003"},{"key":"10.1016\/j.vaccine.2009.03.063_bib12","series-title":"Performance standards for antimicrobial susceptibility testing; twelfth informational supplement","author":"National Committee for Clinical Laboratory Standards","year":"2003"},{"issue":"11","key":"10.1016\/j.vaccine.2009.03.063_bib13","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1128\/AAC.40.11.2562","article-title":"Detection of erythromycin-resistant determinants by PCR","volume":"40","author":"Sutcliffe","year":"1996","journal-title":"Antimicrob Agents Chemother"},{"issue":"12","key":"10.1016\/j.vaccine.2009.03.063_bib14","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1086\/593339","article-title":"Differential effects of pneumococcal vaccines against serotypes 6A and 6C","volume":"198","author":"Park","year":"2008","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2009.03.063_bib15","series-title":"2nd annual public health agency of Canada (PHAC) research forum","article-title":"Outbreak of Streptococcus pneumoniae serotype 5 in Western Canada","author":"Tyrrell","year":"2007"},{"key":"10.1016\/j.vaccine.2009.03.063_bib16","series-title":"47th interscience conference on antimicrobial agents and chemotherapy (ICAAC)","article-title":"Large outbreak of serotype 5 invasive pneumococcal disease in predominantly homeless persons in Calgary, Canada","author":"Twele","year":"2007"},{"key":"10.1016\/j.vaccine.2009.03.063_bib17","series-title":"6th international symposium on pneumococci and pneumococcal diseases (ISPPD), 2008","article-title":"A large outbreak of invasive Streptococcus pneumoniae serotype 5 in western Canada","author":"Tyrrell","year":"2008"},{"issue":"5","key":"10.1016\/j.vaccine.2009.03.063_bib18","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1128\/JCM.38.5.1731-1734.2000","article-title":"Use of clindamycin disks to detect macrolide resistance mediated by erm(B) and mefE in Streptococcus pneumoniae isolates from adults and children","volume":"38","author":"Waites","year":"2000","journal-title":"J Clin Microbiol"},{"issue":"5","key":"10.1016\/j.vaccine.2009.03.063_bib19","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1089\/mdr.1999.5.183","article-title":"Induction of ribosome methylation in MLS-resistant Streptococcus pneumoniae by macrolides and ketolides","volume":"5","author":"Zhong","year":"1999","journal-title":"Microb Drug Resist"},{"issue":"9","key":"10.1016\/j.vaccine.2009.03.063_bib20","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1128\/AAC.44.9.2585-2587.2000","article-title":"Characterization of a genetic element carrying the IV efflux gene, mefA, in Streptococcus pneumoniae","volume":"44","author":"Santagati","year":"2000","journal-title":"Antimicrob Agents Chemother"},{"issue":"8","key":"10.1016\/j.vaccine.2009.03.063_bib21","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1128\/AAC.40.8.1817","article-title":"Streptococcus pneumoniae and Streptococcus pyogenes resistance to macrolides but sensitive to clindamycin, a common resistance pattern mediated by an efflux system","volume":"40","author":"Sutcliffe","year":"1996","journal-title":"Antimicrob Agents Chemother"},{"issue":"9","key":"10.1016\/j.vaccine.2009.03.063_bib22","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1086\/521626","article-title":"Incidence of pneumococcal disease due to non-pneumococcal conjugate vaccine (PCV7) serotypes in the United States during the era of widespread PCV7 vaccination, 1998\u20132004","volume":"196","author":"Hicks","year":"2007","journal-title":"J Infect Dis"},{"issue":"41","key":"10.1016\/j.vaccine.2009.03.063_bib23","first-page":"1077","article-title":"Emergence of antimicrobial-resistant serotype 19A Streptococcus pneumoniae\u2014Massachusetts, 2001\u20132006","volume":"56","author":"Centers for Disease Control and Prevention","year":"2007","journal-title":"MMWR Surveill Summ"},{"issue":"7","key":"10.1016\/j.vaccine.2009.03.063_bib24","doi-asserted-by":"crossref","first-page":"10116","DOI":"10.1086\/528996","article-title":"Population snapshot of emergent Streptococcus pneumoniae serotype 19A in the United States, 2005","volume":"197","author":"Moore","year":"2008","journal-title":"J Infect Dis"},{"issue":"10","key":"10.1016\/j.vaccine.2009.03.063_bib25","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1503\/cmaj.051150","article-title":"Progress in the prevention of pneumococcal infection: the calgary area Streptococcus pneumoniae epidemiology research (CASPER) study","volume":"173","author":"Kellner","year":"2005","journal-title":"CMAJ"},{"issue":"14","key":"10.1016\/j.vaccine.2009.03.063_bib26","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1056\/NEJMoa051642","article-title":"Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae","volume":"354","author":"Kyaw","year":"2006","journal-title":"N Engl J Med"},{"issue":"18","key":"10.1016\/j.vaccine.2009.03.063_bib27","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1056\/NEJMoa022823","article-title":"Decline in invasive pneumococcal disease after the introduction of protein\u2013polysaccharide conjugate vaccine","volume":"348","author":"Whitney","year":"2003","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.vaccine.2009.03.063_bib28","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1128\/JCM.02321-07","article-title":"Changes in serotypes and antimicrobial susceptibility of invasive Streptococcus pneumoniae strains in Cleveland: a quarter century of experience","volume":"46","author":"Jacobs","year":"2008","journal-title":"J Clin Microbiol"},{"issue":"9462","key":"10.1016\/j.vaccine.2009.03.063_bib29","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/S0140-6736(05)71043-6","article-title":"Incidence of macrolide resistance in Streptococcus pneumoniae after introduction of the pneumococcal conjugate vaccine; population-based assessment","volume":"365","author":"Stephens","year":"2005","journal-title":"The Lancet"},{"issue":"4","key":"10.1016\/j.vaccine.2009.03.063_bib30","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1093\/jac\/dkm273","article-title":"Macrolide resistance mechanisms among Streptococcus pneumoniae isolated over 6 years of Canadian respiratory Organism Susceptibility Study (CROSS) (1998\u20132004)","volume":"60","author":"Wierzbowski","year":"2007","journal-title":"J Antimicrob Chemother"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X09004885?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X09004885?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T16:14:02Z","timestamp":1589732042000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X09004885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6]]},"references-count":30,"journal-issue":{"issue":"27","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["S0264410X09004885"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2009.03.063","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,6]]}}}