{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:43:03Z","timestamp":1792784583866,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"15","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"USDA-ARS"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1016\/j.vaccine.2010.01.049","type":"journal-article","created":{"date-parts":[[2010,2,3]],"date-time":"2010-02-03T05:40:11Z","timestamp":1265175611000},"page":"2782-2787","source":"Crossref","is-referenced-by-count":86,"title":["Efficacy of inactivated swine influenza virus vaccines against the 2009 A\/H1N1 influenza virus in pigs"],"prefix":"10.1016","volume":"28","author":[{"given":"Amy L.","family":"Vincent","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janice R.","family":"Ciacci-Zanella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessio","family":"Lorusso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip C.","family":"Gauger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eraldo L.","family":"Zanella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Marcus E.","family":"Kehrli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce H.","family":"Janke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly M.","family":"Lager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2010.01.049_bib1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0065-3527(08)00403-X","article-title":"Swine influenza viruses a North American perspective","volume":"72","author":"Vincent","year":"2008","journal-title":"Adv Virus Res"},{"issue":"March (3)","key":"10.1016\/j.vaccine.2010.01.049_bib2","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1128\/JCM.44.3.1123-1126.2006","article-title":"Identification of human H1N2 and human\u2013swine reassortant H1N2 and H1N1 influenza A viruses among pigs in Ontario, Canada (2003\u20132005)","volume":"44","author":"Karasin","year":"2006","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.vaccine.2010.01.049_bib3","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1007\/s11262-009-0386-6","article-title":"Characterization of a newly emerged genetic cluster of H1N1 and H1N2 swine influenza virus in the United States","volume":"39","author":"Vincent","year":"2009","journal-title":"Virus Genes"},{"key":"10.1016\/j.vaccine.2010.01.049_bib4","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.vetmic.2009.01.003","article-title":"Characterization of an influenza A virus isolated from pigs during an outbreak of respiratory disease in swine and people during a county fair in the United States","volume":"137","author":"Vincent","year":"2009","journal-title":"Vet Microbiol"},{"issue":"July (5937)","key":"10.1016\/j.vaccine.2010.01.049_bib5","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1126\/science.1176225","article-title":"Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans","volume":"325","author":"Garten","year":"2009","journal-title":"Science"},{"issue":"June","key":"10.1016\/j.vaccine.2010.01.049_bib6","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1038\/nature08182","article-title":"Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic","volume":"459","author":"Smith","year":"2009","journal-title":"Nature"},{"issue":"May (2)","key":"10.1016\/j.vaccine.2010.01.049_bib7","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJMp0904572","article-title":"Geographic dependence, surveillance, and origins of the 2009 influenza A (H1N1) virus","volume":"361","author":"Trifonov","year":"2009","journal-title":"N Engl J Med"},{"issue":"April (8)","key":"10.1016\/j.vaccine.2010.01.049_bib8","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1086\/512813","article-title":"Cases of swine influenza in humans: a review of the literature","volume":"44","author":"Myers","year":"2007","journal-title":"Clin Infect Dis"},{"issue":"May (25)","key":"10.1016\/j.vaccine.2010.01.049_bib9","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1056\/NEJMoa0903812","article-title":"Triple-reassortant swine influenza A (H1) in humans in the United States, 2005\u20132009","volume":"360","author":"Shinde","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.vaccine.2010.01.049_bib10","unstructured":"USDA\u2013Animal and Plant Health Inspection Services VS. Code of Federal Regulations, Title 9 Animals and Animal Products. Washington, DC [updated December 30, 2009; cited 2010 January 18]. Available from: http:\/\/edocket.access.gpo.gov\/cfr_2009\/janqtr\/pdf\/9cfr113.113.pdf."},{"key":"10.1016\/j.vaccine.2010.01.049_bib11","doi-asserted-by":"crossref","unstructured":"Vincent AL, Lager KM, Faaberg KS, Harland M, Zanella EL, Ciacci-Zanella JR, et al. Experimental inoculation of pigs with pandemic H1N1 2009 and HI cross-reactivity with contemporary swine influenza virus antisera. Influenza Other Respir Viruses; in press.","DOI":"10.1111\/j.1750-2659.2009.00121.x"},{"issue":"6","key":"10.1016\/j.vaccine.2010.01.049_bib12","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1177\/030098589503200606","article-title":"Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus","volume":"32","author":"Halbur","year":"1995","journal-title":"Vet Pathol"},{"issue":"July (7)","key":"10.1016\/j.vaccine.2010.01.049_bib13","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1128\/JCM.41.7.3198-3205.2003","article-title":"Pathogenic and antigenic properties of phylogenetically distinct reassortant H3N2 swine influenza viruses cocirculating in the United States","volume":"41","author":"Richt","year":"2003","journal-title":"J Clin Microbiol"},{"issue":"September (5)","key":"10.1016\/j.vaccine.2010.01.049_bib14","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1354\/vp.40-5-521","article-title":"Effect of vaccination with selective bacterins on conventional pigs infected with type 2 porcine circovirus","volume":"40","author":"Opriessnig","year":"2003","journal-title":"Vet Pathol"},{"issue":"August (8)","key":"10.1016\/j.vaccine.2010.01.049_bib15","doi-asserted-by":"crossref","first-page":"2491","DOI":"10.1128\/JCM.02366-07","article-title":"Real-time PCR assays to address genetic diversity among strains of Mycoplasma hyopneumoniae","volume":"46","author":"Strait","year":"2008","journal-title":"J Clin Microbiol"},{"issue":"August (3\u20134)","key":"10.1016\/j.vaccine.2010.01.049_bib16","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.vetimm.2006.02.008","article-title":"The immune response and maternal antibody interference to a heterologous H1N1 swine influenza virus infection following vaccination","volume":"112","author":"Kitikoon","year":"2006","journal-title":"Vet Immunol Immunopathol"},{"key":"10.1016\/j.vaccine.2010.01.049_bib17","first-page":"493","article-title":"A simple method of estimating fifty percent endpoints","volume":"27","author":"Reed","year":"1938","journal-title":"Am J Hyg"},{"key":"10.1016\/j.vaccine.2010.01.049_bib18","unstructured":"WHO manual on animal influenza diagnosis and surveillance; 2002 [cited 2009 May 25]. 2nd:[Available from: http:\/\/www.wpro.who.int\/NR\/rdonlyres\/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C\/0\/manualonanimalaidiagnosisandsurveillance.pdf."},{"issue":"January (4)","key":"10.1016\/j.vaccine.2010.01.049_bib19","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.vetmic.2007.07.011","article-title":"Failure of protection and enhanced pneumonia with a US H1N2 swine influenza virus in pigs vaccinated with an inactivated classical swine H1N1 vaccine","volume":"126","author":"Vincent","year":"2008","journal-title":"Vet Microbiol"},{"issue":"September (Pt 9)","key":"10.1016\/j.vaccine.2010.01.049_bib20","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1099\/vir.0.014480-0","article-title":"Pathogenesis and transmission of the novel swine-origin influenza virus A\/H1N1 after experimental infection of pigs","volume":"90","author":"Lange","year":"2009","journal-title":"J Gen Virol"},{"issue":"June (24)","key":"10.1016\/j.vaccine.2010.01.049_bib21","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1136\/vr.164.24.760","article-title":"Influenza A (H1N1) infection in pigs","volume":"164","author":"Brookes","year":"2009","journal-title":"Vet Rec"},{"issue":"August (2)","key":"10.1016\/j.vaccine.2010.01.049_bib22","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1006\/cimm.2001.1835","article-title":"Heterosubtypic immunity against human influenza A viruses, including recently emerged avian H5 and H9 viruses, induced by FLU-ISCOM vaccine in mice requires both cytotoxic T-lymphocyte and macrophage function","volume":"211","author":"Sambhara","year":"2001","journal-title":"Cell Immunol"},{"issue":"December (2)","key":"10.1016\/j.vaccine.2010.01.049_bib23","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.vaccine.2009.09.130","article-title":"Swine influenza matrix 2 (M2) protein contributes to protection against infection with different H1 swine influenza virus (SIV) isolates","volume":"38","author":"Kitikoon","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2010.01.049_bib24","series-title":"Trends in vaccination practices on U.S. swine operations","author":"USDA","year":"1995"},{"key":"10.1016\/j.vaccine.2010.01.049_bib25","series-title":"Trends in vaccination practices for respiratory diseases on U.S. swine operations \u2013 2000","author":"USDA","year":"2003"},{"key":"10.1016\/j.vaccine.2010.01.049_bib26","series-title":"Swine 2006. Part II. Reference of swine health and health management practices in the United States, 2006.","author":"USDA","year":"2007"},{"issue":"September (9)","key":"10.1016\/j.vaccine.2010.01.049_bib27","doi-asserted-by":"crossref","first-page":"7367","DOI":"10.1128\/JVI.72.9.7367-7373.1998","article-title":"Molecular basis for the generation in pigs of influenza A viruses with pandemic potential","volume":"72","author":"Ito","year":"1998","journal-title":"J Virol"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X10001039?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X10001039?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T04:43:53Z","timestamp":1590554633000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X10001039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":27,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["S0264410X10001039"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2010.01.049","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3]]}}}