{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T05:07:54Z","timestamp":1740632874921,"version":"3.38.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"50","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000276","name":"Department of Health, UK","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000276","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.vaccine.2010.09.061","type":"journal-article","created":{"date-parts":[[2010,10,4]],"date-time":"2010-10-04T09:24:00Z","timestamp":1286184240000},"page":"7979-7986","source":"Crossref","is-referenced-by-count":6,"title":["Temporal changes in the gene signatures of BCG-vaccinated guinea pigs in response to different mycobacterial antigens"],"prefix":"10.1016","volume":"28","author":[{"given":"Julia A.","family":"Tree","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyoti","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth E.","family":"Thom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Elmore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hubert","family":"Sch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip D.","family":"Marsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2010.09.061_bib0005","series-title":"Tuberculosis","first-page":"875","article-title":"Bacille Calmette-Gurein: efficiency and immunity","author":"Moreira","year":"2005"},{"issue":"Mar (9)","key":"10.1016\/j.vaccine.2010.09.061_bib0010","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1001\/jama.1994.03510330076038","article-title":"Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature","volume":"271","author":"Colditz","year":"1994","journal-title":"JAMA"},{"issue":"Sep (Suppl. 3)","key":"10.1016\/j.vaccine.2010.09.061_bib0015","doi-asserted-by":"crossref","first-page":"S64","DOI":"10.1086\/314072","article-title":"Preventing tuberculosis with bacillus Calmette-Guerin vaccine: a meta-analysis of the literature","volume":"31","author":"Brewer","year":"2000","journal-title":"Clin Infect Dis"},{"issue":"May (19)","key":"10.1016\/j.vaccine.2010.09.061_bib0020","doi-asserted-by":"crossref","first-page":"3742","DOI":"10.1016\/j.vaccine.2007.01.112","article-title":"Current status of TB vaccines","volume":"25","author":"Gupta","year":"2007","journal-title":"Vaccine"},{"issue":"Jan\u2013Mar (1\u20132)","key":"10.1016\/j.vaccine.2010.09.061_bib0025","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.tube.2004.09.009","article-title":"Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis","volume":"85","author":"Williams","year":"2005","journal-title":"Tuberculosis (Edinburgh, Scotland)"},{"issue":"Apr (4)","key":"10.1016\/j.vaccine.2010.09.061_bib0030","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1128\/IAI.71.4.1672-1679.2003","article-title":"A new vaccine against tuberculosis affords greater survival after challenge than the current vaccine in the guinea pig model of pulmonary tuberculosis","volume":"71","author":"Horwitz","year":"2003","journal-title":"Infect Immun"},{"issue":"Feb (5)","key":"10.1016\/j.vaccine.2010.09.061_bib0035","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1073\/pnas.92.5.1530","article-title":"Protective immunity against tuberculosis induced by vaccination with major extracellular proteins of Mycobacterium tuberculosis","volume":"92","author":"Horwitz","year":"1995","journal-title":"Proc Nat Acad Sci USA"},{"key":"10.1016\/j.vaccine.2010.09.061_bib0040","series-title":"Tuberculosis and the tubercle bacillus","first-page":"547","article-title":"Animal models of tuberculosis","author":"Flynn","year":"2005"},{"issue":"Nov (6)","key":"10.1016\/j.vaccine.2010.09.061_bib0045","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.tube.2009.08.004","article-title":"Evaluation of new vaccines for tuberculosis in the guinea pig model","volume":"89","author":"Williams","year":"2009","journal-title":"Tuberculosis (Edinburgh, Scotland)"},{"issue":"Feb (2)","key":"10.1016\/j.vaccine.2010.09.061_bib0050","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1128\/IAI.74.2.1436-1441.2006","article-title":"Development of a guinea pig immune response-related microarray and its use to define the host response following Mycobacterium bovis BCG vaccination","volume":"74","author":"Tree","year":"2006","journal-title":"Infect Immun"},{"issue":"Jul (7)","key":"10.1016\/j.vaccine.2010.09.061_bib0055","doi-asserted-by":"crossref","first-page":"e81","DOI":"10.1371\/journal.pcbi.0020081","article-title":"From functional genomics to functional immunomics: new challenges, old problems, big rewards","volume":"2","author":"Braga-Neto","year":"2006","journal-title":"PLoS Comput Biol"},{"issue":"Jun (3)","key":"10.1016\/j.vaccine.2010.09.061_bib0060","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.coi.2010.04.006","article-title":"Novel tuberculosis vaccines on the horizon","volume":"22","author":"Parida","year":"2010","journal-title":"Curr Opin Immun"},{"issue":"Dec (3)","key":"10.1016\/j.vaccine.2010.09.061_bib0065","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1365-2249.2004.02648.x","article-title":"Intranasal bacille Calmette-Guerin (BCG) vaccine dosage needs balancing between protection and lung pathology","volume":"138","author":"Tree","year":"2004","journal-title":"Clin Exp Immun"},{"issue":"Mar (3)","key":"10.1016\/j.vaccine.2010.09.061_bib0070","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1128\/IAI.70.3.1245-1253.2002","article-title":"Effect of Mycobacterium bovis BCG vaccination on interleukin-1 beta and RANTES mRNA expression in guinea pig cells exposed to attenuated and virulent mycobacteria","volume":"70","author":"Jeevan","year":"2002","journal-title":"Infect Immun"},{"issue":"10","key":"10.1016\/j.vaccine.2010.09.061_bib0075","doi-asserted-by":"crossref","first-page":"R80","DOI":"10.1186\/gb-2004-5-10-r80","article-title":"Bioconductor: open software development for computational biology and bioinformatics","volume":"5","author":"Gentleman","year":"2004","journal-title":"Genome Biol"},{"key":"10.1016\/j.vaccine.2010.09.061_bib0080","first-page":"3","article-title":"Linear models and empirical Bayes methods for assessing differential expression in microarray experiments","volume":"3","author":"Smyth","year":"2004","journal-title":"Stat Appl Gen Mol Biol"},{"unstructured":"Smyth GK, Thorne N, Wettenhall J. Limma: linear models for microarray data. Available from: http:\/\/bioinf.wehi.edu.au\/limma\/usersguide.pdf; 2005","key":"10.1016\/j.vaccine.2010.09.061_bib0085"},{"key":"10.1016\/j.vaccine.2010.09.061_bib0090","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J Roy Stat Soc Ser B"},{"issue":"Dec (1\u20132)","key":"10.1016\/j.vaccine.2010.09.061_bib0095","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.jim.2007.08.012","article-title":"Monoclonal antibodies to guinea pig interferon-gamma: tools for cytokine detection and neutralization","volume":"328","author":"Schafer","year":"2007","journal-title":"J Immunol Meth"},{"issue":"Oct (4)","key":"10.1016\/j.vaccine.2010.09.061_bib0100","first-page":"213","article-title":"Immunology of tuberculosis","volume":"120","author":"Raja","year":"2004","journal-title":"Indian J Med Res"},{"issue":"Jan (1)","key":"10.1016\/j.vaccine.2010.09.061_bib0105","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.tube.2007.09.002","article-title":"Increased expression of host iron-binding proteins precedes iron accumulation and calcification of primary lung lesions in experimental tuberculosis in the guinea pig","volume":"88","author":"Basaraba","year":"2008","journal-title":"Tuberculosis (Edinburgh, Scotland)"},{"issue":"Feb (4)","key":"10.1016\/j.vaccine.2010.09.061_bib0110","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.cell.2006.02.019","article-title":"Translating innate immunity into immunological memory: implications for vaccine development","volume":"124","author":"Pulendran","year":"2006","journal-title":"Cell"},{"issue":"Sep (9)","key":"10.1016\/j.vaccine.2010.09.061_bib0115","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1038\/ni1497","article-title":"Development, cytokine profile and function of human interleukin 17-producing helper T cells","volume":"8","author":"Wilson","year":"2007","journal-title":"Nat Immunol"},{"issue":"October (10)","key":"10.1016\/j.vaccine.2010.09.061_bib0155","doi-asserted-by":"crossref","first-page":"4187","DOI":"10.1128\/IAI.01392-09","article-title":"Mycobacterium bovis BCG-specific Th17 cells confer partial protection against Mycobacterium tuberculosis infection in the absence of gamma interferon","volume":"78","author":"Wozniak","year":"2010","journal-title":"Infect Immun"},{"issue":"11","key":"10.1016\/j.vaccine.2010.09.061_bib0125","doi-asserted-by":"crossref","first-page":"e3683","DOI":"10.1371\/journal.pone.0003683","article-title":"Adult-like anti-mycobacterial T cell and in vivo dendritic cell responses following neonatal immunization with Ag85B-ESAT-6 in the IC31 adjuvant","volume":"3","author":"Kamath","year":"2008","journal-title":"PloS One"},{"issue":"Oct (7)","key":"10.1016\/j.vaccine.2010.09.061_bib0130","doi-asserted-by":"crossref","first-page":"4955","DOI":"10.4049\/jimmunol.181.7.4955","article-title":"Multifunctional, high-level cytokine-producing Th1 cells in the lung, but not spleen, correlate with protection against Mycobacterium tuberculosis aerosol challenge in mice","volume":"181","author":"Forbes","year":"2008","journal-title":"J Immunol"},{"issue":"Jun (12)","key":"10.1016\/j.vaccine.2010.09.061_bib0135","doi-asserted-by":"crossref","first-page":"8047","DOI":"10.4049\/jimmunol.0801592","article-title":"Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells","volume":"182","author":"Lindenstrom","year":"2009","journal-title":"J Immunol"},{"issue":"6","key":"10.1016\/j.vaccine.2010.09.061_bib0140","doi-asserted-by":"crossref","first-page":"e5771","DOI":"10.1371\/journal.pone.0005771","article-title":"A liposome-based mycobacterial vaccine induces potent adult and neonatal multifunctional T cells through the exquisite targeting of dendritic cells","volume":"4","author":"Kamath","year":"2009","journal-title":"PloS One"},{"issue":"Jun (6)","key":"10.1016\/j.vaccine.2010.09.061_bib0145","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1189\/jlb.1204723","article-title":"Disruption of granulocyte macrophage-colony stimulating factor production in the lungs severely affects the ability of mice to control Mycobacterium tuberculosis infection","volume":"77","author":"Gonzalez-Juarrero","year":"2005","journal-title":"J Leukoc Biol"},{"issue":"Jan (1)","key":"10.1016\/j.vaccine.2010.09.061_bib0150","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/eji.200939665","article-title":"Modulation of pulmonary DC function by vaccine-encoded GM-CSF enhances protective immunity against Mycobacterium tuberculosis infection","volume":"40","author":"Nambiar","year":"2010","journal-title":"Eur J Immunol"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X10013824?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X10013824?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T05:22:08Z","timestamp":1740547328000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X10013824"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":30,"journal-issue":{"issue":"50","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0264410X10013824"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2010.09.061","relation":{},"ISSN":["0264-410X"],"issn-type":[{"type":"print","value":"0264-410X"}],"subject":[],"published":{"date-parts":[[2010,11]]}}}