{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T13:57:35Z","timestamp":1790863055906,"version":"4.1.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"50","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":988,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.vaccine.2010.09.092","type":"journal-article","created":{"date-parts":[[2010,10,11]],"date-time":"2010-10-11T14:47:22Z","timestamp":1286808442000},"page":"7865-7872","source":"Crossref","is-referenced-by-count":54,"title":["Comparison of the safety and immunogenicity of an investigational and a licensed quadrivalent meningococcal conjugate vaccine in children 2\u201310 years of age"],"prefix":"10.1016","volume":"28","author":[{"given":"Scott A.","family":"Halperin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Jeanfreau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola P.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Reisinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Walter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Bedell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Gill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter M.","family":"Dull","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2010.09.092_bib0005","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1086\/520303","article-title":"Complications and sequelae of meningococcal disease in Quebec, Canada, 1990\u20131994","volume":"26","author":"Erickson","year":"1998","journal-title":"Clin Infect Dis"},{"issue":"5","key":"10.1016\/j.vaccine.2010.09.092_bib0010","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/01.inf.0000259996.95965.ef","article-title":"Use of meningococcal vaccines in the United States","volume":"26","author":"Bilukha","year":"2007","journal-title":"Pediatr Infect Dis J"},{"issue":"12 Suppl.","key":"10.1016\/j.vaccine.2010.09.092_bib0015","doi-asserted-by":"crossref","first-page":"S274","DOI":"10.1097\/01.inf.0000147642.85129.05","article-title":"Global epidemiology of meningococcal disease and vaccine efficacy","volume":"23","author":"Pollard","year":"2004","journal-title":"Pediatr Infect Dis J"},{"issue":"Suppl.","key":"10.1016\/j.vaccine.2010.09.092_bib0020","doi-asserted-by":"crossref","first-page":"B51","DOI":"10.1016\/j.vaccine.2009.04.063","article-title":"Global epidemiology of meningococcal disease","volume":"27","author":"Harrison","year":"2009","journal-title":"Vaccine"},{"issue":"Suppl.","key":"10.1016\/j.vaccine.2010.09.092_bib0025","doi-asserted-by":"crossref","first-page":"B13","DOI":"10.1016\/j.vaccine.2009.04.062","article-title":"Epidemic meningitis due to Group A Neisseria meningitidis in hte African meningitis belt: a persistent problem with an imminent solution","volume":"17","author":"LaForce","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0030","unstructured":"Centers for Disease Control and Prevention. Active Bacterial Core Surveillence Reports, Emerging Infectious Program Network, Neisseria meningitidis; 2005."},{"key":"10.1016\/j.vaccine.2010.09.092_bib0035","series-title":"Control of epidemic meningococcal disease: WHO practical guidelines","author":"World Health Organisation","year":"1998"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0040","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1086\/649209","article-title":"Changes in Neisseria meningitidis disease epidemiology in the United States, 1998\u20132007: implications for prevention of meningococcal disease","volume":"50","author":"Cohn","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0045","doi-asserted-by":"crossref","first-page":"S117","DOI":"10.1097\/00006454-199809001-00005","article-title":"Haemophilus influenzae type b conjugate vaccines: a review of efficacy data","volume":"17","author":"Heath","year":"1998","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0050","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1056\/NEJMoa022823","article-title":"Active Bacterial Core Surveillance of the Emerging Infections Program Network. Decline in invasive pneumococcal disease after the introduction of protein\u2013polysaccharide conjugate vaccine","volume":"348","author":"Whitney","year":"2003","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.vaccine.2010.09.092_bib0055","doi-asserted-by":"crossref","first-page":"108","DOI":"10.5694\/j.1326-5377.2007.tb00828.x","article-title":"Impact of meningococcal C conjugate vaccine use in Australia","volume":"186","author":"Booy","year":"2007","journal-title":"Med J Aust"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0060","doi-asserted-by":"crossref","first-page":"4097","DOI":"10.1016\/j.vaccine.2005.03.045","article-title":"Impact and effectiveness of meningococcal C conjugate vaccine following its introduction in Spain","volume":"23","author":"Larrauri","year":"2005","journal-title":"Vaccine"},{"issue":"Suppl.","key":"10.1016\/j.vaccine.2010.09.092_bib0065","doi-asserted-by":"crossref","first-page":"B20","DOI":"10.1016\/j.vaccine.2009.04.067","article-title":"Meningococcal C conjugate vaccine: the experience in England and Wales","volume":"27","author":"Campbell","year":"2009","journal-title":"Vaccine"},{"issue":"11","key":"10.1016\/j.vaccine.2010.09.092_bib0070","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1517\/14712598.5.11.1475","article-title":"Meningococcal conjugate vaccines","volume":"5","author":"Pichichero","year":"2005","journal-title":"Expert Opin Biol Ther"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0075","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1001\/jama.280.19.1685","article-title":"Induction of immunologic memory by conjugated vs. plain meningococcal C polysaccharide vaccine in toddlers: a randomized controlled trial","volume":"280","author":"MacDonald","year":"1998","journal-title":"JAMA"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0080","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1097\/INF.0b013e3181861dba","article-title":"Demonstration of immunologic memory using serogroup C meningococcal glycoconjugate vaccine","volume":"28","author":"Snape","year":"2009","journal-title":"Pediatr Infect Dis J"},{"issue":"1","key":"10.1016\/j.vaccine.2010.09.092_bib0085","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S1473-3099(04)01251-4","article-title":"Meningococcal polysaccharide\u2013protein conjugate vaccines","volume":"5","author":"Snape","year":"2005","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0090","first-page":"794","article-title":"Revised recommendations of the Advisory Committee on Immunization Practices to vaccinate all personas aged 11\u201318 years with meningococcal conjugate vaccine","volume":"56","author":"Centers for Disease Control and Prevention","year":"2007","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0095","first-page":"462","article-title":"Report from the Advisory Committee on Immunization Practices (ACIP): decision not to recommend routine immunization of all children aged 2\u201310 years with quadrivalent meningococcal conjugate vaccine (MCV4)","volume":"57","author":"Centers for Disease Control and Prevention","year":"2008","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0100","first-page":"1265","article-title":"Notice to readers: Recommendations from the Advisory Committee on Immunization Practices (ACIP) for use of quadrivalent meningococcal conjugate vaccine (MCV4) in children aged 2\u201310 years at increased risk for invasive meninogocccal disease","volume":"56","author":"Centers for Disease Control and Prevention (CDC)","year":"2007","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0105","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1001\/jama.2007.29-c","article-title":"Immunogenicity of a tetravalent meningococcal glycoconjugate vaccine in infants: a randomized controlled trial","volume":"299","author":"Snape","year":"2008","journal-title":"JAMA"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0110","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1097\/INF.0b013e31818e037d","article-title":"Immunogenicity and immune memory of a nonadjuvanted quadrivalent meningococcal glycoconjugate vaccine in infants","volume":"28","author":"Perrett","year":"2009","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0115","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s10096-009-0848-8","article-title":"Safety and immunogenicity of an investigational quadrivalent meningococcal conjugate vaccine after one or two doses given to infants and toddlers","volume":"29","author":"Halperin","year":"2010","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0120","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.vaccine.2009.10.104","article-title":"Immunogenicity and tolerability of a quadrivalent meningococcal glycoconjugate vaccine in children 2\u201310 years of age","volume":"28","author":"Black","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0125","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1086\/500512","article-title":"Antibody persistence 3 years after immunization of adolescents with quadrivalent meningococcal conjugate vaccine","volume":"193","author":"Vu","year":"2006","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0130","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1084\/jem.129.6.1307","article-title":"Human immunity to the meningococcus. I. The role of humoral antibodies","volume":"129","author":"Goldschneider","year":"1969","journal-title":"J Exp Med"},{"issue":"Suppl.","key":"10.1016\/j.vaccine.2010.09.092_bib0135","doi-asserted-by":"crossref","first-page":"B112","DOI":"10.1016\/j.vaccine.2009.04.065","article-title":"Bactericidal antibody is the immunological surrogate of protection against meninogococcal disease","volume":"27","author":"Fracsch","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0140","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/S0264-410X(02)00630-8","article-title":"Seroprevalence of meningococcal serogroup C bactericidal antibody in England and Wales in the pre-vaccination era","volume":"21","author":"Trotter","year":"2003","journal-title":"Vaccine"},{"issue":"Suppl.","key":"10.1016\/j.vaccine.2010.09.092_bib0145","doi-asserted-by":"crossref","first-page":"B117","DOI":"10.1016\/j.vaccine.2009.04.066","article-title":"Relative importance of complement-mediated bactericidal and opsonic activity for protection against meningococcal disease","volume":"27","author":"Granoff","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0150","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1084\/jem.129.6.1327","article-title":"Human immunity to the meningococcus. II. Development of natural immunity","volume":"129","author":"Goldschneider","year":"1969","journal-title":"J Exp Med"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0155","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1001\/jama.285.2.177","article-title":"Effectiveness of a mass immunization campaign against serogroup C meningococcal disease in Quebec","volume":"285","author":"De Wals","year":"2001","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.vaccine.2010.09.092_bib0160","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1086\/599117","article-title":"Phase III comparison of an investigational quadrivalent meningococcal conjugate vaccine with the licensed meningococcal ACWY conjugate vaccine in adolescents","volume":"49","author":"Jackson","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2010.09.092_bib0165","unstructured":"Public Health Agency of Canada. http:\/\/www.phac-aspc.gc.ca\/im\/ptimprog-progimpt\/table-1-eng.php [accessed 01.05.10]."},{"key":"10.1016\/j.vaccine.2010.09.092_bib0170","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1086\/652765","article-title":"Antibody persistence after serogroup C meningococcal conjugate immunization of United Kingdom primary-school children in 1999\u20132000 and response to a booster: a phase 4 clinical trial","volume":"50","author":"Perrett","year":"2010","journal-title":"Clin Infect Dis"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X10014349?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X10014349?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T17:14:14Z","timestamp":1636650854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X10014349"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":34,"journal-issue":{"issue":"50","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0264410X10014349"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2010.09.092","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11]]}}}