{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:46:23Z","timestamp":1793123183372,"version":"4.5.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"15","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1016\/j.vaccine.2011.01.090","type":"journal-article","created":{"date-parts":[[2011,2,12]],"date-time":"2011-02-12T10:43:51Z","timestamp":1297507431000},"page":"2749-2755","source":"Crossref","is-referenced-by-count":21,"title":["Efficacy of vaccination strategies against intranasal challenge with Brucella abortus in BALB\/c mice"],"prefix":"10.1016","volume":"29","author":[{"given":"Naveen","family":"Surendran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nammalwar","family":"Sriranganathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Lawler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen M.","family":"Boyle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth M.","family":"Hiltbold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Heid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt","family":"Zimmerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon G.","family":"Witonsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2011.01.090_bib0005","series-title":"Zoonoses and communicable diseases common to man and animal","year":"2001"},{"key":"10.1016\/j.vaccine.2011.01.090_bib0010","series-title":"Brucellosis in humans and animals","year":"2006"},{"issue":"October (10)","key":"10.1016\/j.vaccine.2011.01.090_bib0015","doi-asserted-by":"crossref","first-page":"4923","DOI":"10.1128\/IAI.00451-07","article-title":"Aerosol infection of BALB\/c mice with Brucella melitensis and Brucella abortus and protective efficacy against aerosol challenge","volume":"75","author":"Kahl-McDonagh","year":"2007","journal-title":"Infect Immun"},{"issue":"May (5)","key":"10.1016\/j.vaccine.2011.01.090_bib0020","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1128\/CVI.00029-09","article-title":"Development and characterization of mouse models of infection with aerosolized Brucella melitensis and Brucella suis","volume":"16","author":"Smither","year":"2009","journal-title":"Clin Vaccine Immunol"},{"issue":"October (19\u201320)","key":"10.1016\/j.vaccine.2011.01.090_bib0025","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1007\/s00018-006-6311-4","article-title":"Brucella as a biological weapon","volume":"63","author":"Pappas","year":"2006","journal-title":"Cell Mol Life Sci"},{"issue":"December (12)","key":"10.1016\/j.vaccine.2011.01.090_bib0030","first-page":"E15","article-title":"Bichat guidelines for the clinical management of brucellosis and bioterrorism-related brucellosis","volume":"9","author":"Bossi","year":"2004","journal-title":"Euro Surveill"},{"issue":"November (11)","key":"10.1016\/j.vaccine.2011.01.090_bib0035","doi-asserted-by":"crossref","first-page":"4990","DOI":"10.1128\/IAI.62.11.4990-4996.1994","article-title":"Vaccination with Brucella abortus rough mutant RB51 protects BALB\/c mice against virulent strains of Brucella abortus, Brucella melitensis, and Brucella ovis","volume":"62","author":"Jimenez de Bagues","year":"1994","journal-title":"Infect Immun"},{"issue":"October (10)","key":"10.1016\/j.vaccine.2011.01.090_bib0040","doi-asserted-by":"crossref","first-page":"5820","DOI":"10.1128\/IAI.00331-06","article-title":"Comparison of protective efficacy of subcutaneous versus intranasal immunization of mice with a Brucella melitensis lipopolysaccharide subunit vaccine","volume":"74","author":"Bhattacharjee","year":"2006","journal-title":"Infect Immun"},{"issue":"March (3)","key":"10.1016\/j.vaccine.2011.01.090_bib0045","doi-asserted-by":"crossref","first-page":"398","DOI":"10.2460\/ajvr.2001.62.398","article-title":"Bacteriologic and histologic features in mice after intranasal inoculation of Brucella melitensis","volume":"62","author":"Mense","year":"2001","journal-title":"Am J Vet Res"},{"issue":"8","key":"10.1016\/j.vaccine.2011.01.090_bib0050","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/j.1863-2378.2007.01063.x","article-title":"An aerosolized Brucella spp. challenge model for laboratory animals","volume":"54","author":"Olsen","year":"2007","journal-title":"Zoonoses Public Health"},{"issue":"May (5)","key":"10.1016\/j.vaccine.2011.01.090_bib0055","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.1128\/IAI.71.5.2326-2330.2003","article-title":"Brucella abortus RB51 induces protection in mice orally infected with the virulent strain B. abortus 2308","volume":"71","author":"Pasquali","year":"2003","journal-title":"Infect Immun"},{"issue":"July (2)","key":"10.1016\/j.vaccine.2011.01.090_bib0060","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0378-1135(91)90091-S","article-title":"Biological properties of RB51; a stable rough strain of Brucella abortus","volume":"28","author":"Schurig","year":"1991","journal-title":"Vet Microbiol"},{"issue":"June (6)","key":"10.1016\/j.vaccine.2011.01.090_bib0065","doi-asserted-by":"crossref","first-page":"3286","DOI":"10.1128\/IAI.68.6.3286-3289.2000","article-title":"Overexpression of protective antigen as a novel approach to enhance vaccine efficacy of Brucella abortus strain RB51","volume":"68","author":"Vemulapalli","year":"2000","journal-title":"Infect Immun"},{"issue":"May (5)","key":"10.1016\/j.vaccine.2011.01.090_bib0070","doi-asserted-by":"crossref","first-page":"644","DOI":"10.2460\/ajvr.2004.65.644","article-title":"Pathologic changes associated with brucellosis experimentally induced by aerosol exposure in rhesus macaques (Macaca mulatta)","volume":"65","author":"Mense","year":"2004","journal-title":"Am J Vet Res"},{"issue":"February (2)","key":"10.1016\/j.vaccine.2011.01.090_bib0075","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/nri1777","article-title":"Mucosal vaccines: the promise and the challenge","volume":"6","author":"Neutra","year":"2006","journal-title":"Nat Rev Immunol"},{"issue":"December (12)","key":"10.1016\/j.vaccine.2011.01.090_bib0080","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1084\/jem.20021340","article-title":"Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen","volume":"196","author":"Eisenbarth","year":"2002","journal-title":"J Exp Med"},{"issue":"April (4)","key":"10.1016\/j.vaccine.2011.01.090_bib0085","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.micinf.2009.01.010","article-title":"Smooth Brucella strains invade and replicate in human lung epithelial cells without inducing cell death","volume":"11","author":"Ferrero","year":"2009","journal-title":"Microbes Infect"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X11001629?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X11001629?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,6,16]],"date-time":"2020-06-16T14:07:43Z","timestamp":1592316463000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X11001629"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":17,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["S0264410X11001629"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2011.01.090","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}