{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T10:55:05Z","timestamp":1784804105016,"version":"3.55.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"46","license":[{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases (NIAID)\/NIH","doi-asserted-by":"crossref","award":["U54 AI057156"],"award-info":[{"award-number":["U54 AI057156"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Louisiana Vaccine Center\/South Louisiana Institute for Infectious Disease Research Cooperative Pilot Research"},{"name":"Tulane Research Enhancement Grant"},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases Grant","doi-asserted-by":"crossref","award":["U54AI065359"],"award-info":[{"award-number":["U54AI065359"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases Grant","doi-asserted-by":"crossref","award":["1U01AI078008-3"],"award-info":[{"award-number":["1U01AI078008-3"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1016\/j.vaccine.2011.08.058","type":"journal-article","created":{"date-parts":[[2011,8,25]],"date-time":"2011-08-25T21:18:39Z","timestamp":1314307119000},"page":"8381-8389","source":"Crossref","is-referenced-by-count":107,"title":["A naturally derived outer-membrane vesicle vaccine protects against lethal pulmonary Burkholderia pseudomallei infection"],"prefix":"10.1016","volume":"29","author":[{"given":"Wildaliz","family":"Nieves","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saja","family":"Asakrah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Qazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine A.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Kurtz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"AuCoin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James B.","family":"McLachlan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chad J.","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa A.","family":"Morici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.vaccine.2011.08.058_bib0005","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1111\/j.1469-0691.2010.03237.x","article-title":"Burkholderia cenocepacia in cystic fibrosis: epidemiology and molecular mechanisms of virulence","volume":"16","author":"Drevinek","year":"2010","journal-title":"Clin Microbiol Infect"},{"issue":"2","key":"10.1016\/j.vaccine.2011.08.058_bib0010","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1574-6968.2007.00949.x","article-title":"Glanders: off to the races with Burkholderia mallei","volume":"277","author":"Whitlock","year":"2007","journal-title":"FEMS Microbiol Lett"},{"issue":"2","key":"10.1016\/j.vaccine.2011.08.058_bib0015","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1128\/CMR.18.2.383-416.2005","article-title":"Melioidosis: epidemiology, pathophysiology, and management","volume":"18","author":"Cheng","year":"2005","journal-title":"Clin Microbiol Rev"},{"issue":"4","key":"10.1016\/j.vaccine.2011.08.058_bib0020","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/nrmicro1385","article-title":"Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei","volume":"4","author":"Wiersinga","year":"2006","journal-title":"Nat Rev Microbiol"},{"issue":"2\u20133","key":"10.1016\/j.vaccine.2011.08.058_bib0025","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0001-706X(99)00059-5","article-title":"Melioidosis as an emerging global problem","volume":"74","author":"Dance","year":"2000","journal-title":"Acta Trop"},{"issue":"9","key":"10.1016\/j.vaccine.2011.08.058_bib0030","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1586\/14760584.7.9.1357","article-title":"Strategies toward vaccines against Burkholderia mallei and Burkholderia pseudomallei","volume":"7","author":"Bondi","year":"2008","journal-title":"Expert Rev Vaccines"},{"issue":"8","key":"10.1016\/j.vaccine.2011.08.058_bib0035","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1016\/j.clinthera.2010.07.020","article-title":"Progress toward development of vaccines against melioidosis: a review","volume":"32","author":"Sarkar-Tyson","year":"2010","journal-title":"Clin Ther"},{"issue":"9","key":"10.1016\/j.vaccine.2011.08.058_bib0040","doi-asserted-by":"crossref","first-page":"5290","DOI":"10.1128\/IAI.70.9.5290-5294.2002","article-title":"A mutant of Burkholderia pseudomallei, auxotrophic in the branched chain amino acid biosynthetic pathway, is attenuated and protective in a murine model of melioidosis","volume":"70","author":"Atkins","year":"2002","journal-title":"Infect Immun"},{"issue":"9","key":"10.1016\/j.vaccine.2011.08.058_bib0045","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1086\/508217","article-title":"A live experimental vaccine against Burkholderia pseudomallei elicits CD4+ T cell-mediated immunity, priming T cells specific for 2 type III secretion system proteins","volume":"194","author":"Haque","year":"2006","journal-title":"J Infect Dis"},{"issue":"7","key":"10.1016\/j.vaccine.2011.08.058_bib0050","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/sj.icb.7100084","article-title":"Development of protective immunity in a murine model of melioidosis is influenced by the source of Burkholderia pseudomallei antigens","volume":"85","author":"Barnes","year":"2007","journal-title":"Immunol Cell Biol"},{"issue":"12","key":"10.1016\/j.vaccine.2011.08.058_bib0055","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1099\/0022-1317-51-12-1055","article-title":"Passive protection against Burkholderia pseudomallei infection in mice by monoclonal antibodies against capsular polysaccharide, lipopolysaccharide or proteins","volume":"51","author":"Jones","year":"2002","journal-title":"J Med Microbiol"},{"issue":"Pt 12","key":"10.1016\/j.vaccine.2011.08.058_bib0060","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1099\/jmm.0.45766-0","article-title":"Evaluation of lipopolysaccharide and capsular polysaccharide as subunit vaccines against experimental melioidosis","volume":"53","author":"Nelson","year":"2004","journal-title":"J Med Microbiol"},{"issue":"47","key":"10.1016\/j.vaccine.2011.08.058_bib0065","doi-asserted-by":"crossref","first-page":"7551","DOI":"10.1016\/j.vaccine.2010.08.058","article-title":"Lipopolysaccharide from Burkholderia thailandensis E264 provides protection in a murine model of melioidosis","volume":"28","author":"Ngugi","year":"2010","journal-title":"Vaccine"},{"issue":"5","key":"10.1016\/j.vaccine.2011.08.058_bib0070","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1128\/CVI.00533-10","article-title":"In vitro and in vivo studies of monoclonal antibodies with prominent bactericidal activity against Burkholderia pseudomallei and Burkholderia mallei","volume":"18","author":"Zhang","year":"2011","journal-title":"Clin Vaccine Immunol"},{"issue":"8","key":"10.1016\/j.vaccine.2011.08.058_bib0075","doi-asserted-by":"crossref","first-page":"4173","DOI":"10.1128\/IAI.00404-07","article-title":"Identification of a LolC homologue in Burkholderia pseudomallei, a novel protective antigen for melioidosis","volume":"75","author":"Harland","year":"2007","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.vaccine.2011.08.058_bib0080","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1574-695X.2007.00345.x","article-title":"Evaluating Burkholderia pseudomallei Bip proteins as vaccines and Bip antibodies as detection agents","volume":"52","author":"Druar","year":"2008","journal-title":"FEMS Immunol Med Microbiol"},{"issue":"8","key":"10.1016\/j.vaccine.2011.08.058_bib0085","doi-asserted-by":"crossref","first-page":"e6496","DOI":"10.1371\/journal.pone.0006496","article-title":"Immunogenic Burkholderia pseudomallei outer membrane proteins as potential candidate vaccine targets","volume":"4","author":"Hara","year":"2009","journal-title":"PLoS One"},{"issue":"31","key":"10.1016\/j.vaccine.2011.08.058_bib0320","doi-asserted-by":"crossref","first-page":"5005","DOI":"10.1016\/j.vaccine.2010.05.022","article-title":"Immunization with the recombinant Burkholderia pseudomallei outer membrane protein Omp85 induces protective immunity in mice","volume":"28","author":"Su","year":"2010","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.vaccine.2011.08.058_bib0095","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1128\/IAI.71.1.584-587.2003","article-title":"Biodefense-driven murine model of pneumonic melioidosis","volume":"71","author":"Jeddeloh","year":"2003","journal-title":"Infect Immun"},{"issue":"9","key":"10.1016\/j.vaccine.2011.08.058_bib0100","doi-asserted-by":"crossref","first-page":"5945","DOI":"10.1128\/IAI.73.9.5945-5951.2005","article-title":"Humoral and cell-mediated adaptive immune responses are required for protection against Burkholderia pseudomallei challenge and bacterial clearance postinfection","volume":"73","author":"Healey","year":"2005","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2011.08.058_bib0105","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1146\/annurev.micro.091208.073413","article-title":"Biological functions and biogenesis of secreted bacterial outer membrane vesicles","volume":"64","author":"Kulp","year":"2010","journal-title":"Annu Rev Microbiol"},{"issue":"11","key":"10.1016\/j.vaccine.2011.08.058_bib0110","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.micinf.2010.05.008","article-title":"Outer membrane vesicles function as offensive weapons in host-parasite interactions","volume":"12","author":"Amano","year":"2010","journal-title":"Microbes Infect"},{"issue":"6","key":"10.1016\/j.vaccine.2011.08.058_bib0115","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1111\/j.1365-2958.2009.06731.x","article-title":"Biogenesis of bacterial membrane vesicles","volume":"72","author":"Deatherage","year":"2009","journal-title":"Mol Microbiol"},{"issue":"suppl. 2","key":"10.1016\/j.vaccine.2011.08.058_bib0120","doi-asserted-by":"crossref","first-page":"B3","DOI":"10.1016\/j.vaccine.2009.04.071","article-title":"Properties and clinical performance of vaccines containing outer membrane vesicles from Neisseria meningitidis","volume":"27","author":"Holst","year":"2009","journal-title":"Vaccine"},{"issue":"12","key":"10.1016\/j.vaccine.2011.08.058_bib0125","doi-asserted-by":"crossref","first-page":"e15692","DOI":"10.1371\/journal.pone.0015692","article-title":"Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis","volume":"5","author":"Fransen","year":"2010","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.vaccine.2011.08.058_bib0130","doi-asserted-by":"crossref","first-page":"7692","DOI":"10.4049\/jimmunol.179.11.7692","article-title":"Membrane vesicles are immunogenic facsimiles of Salmonella typhimurium that potently activate dendritic cells, prime B and T cell responses, and stimulate protective immunity in vivo","volume":"179","author":"Alaniz","year":"2007","journal-title":"J Immunol"},{"issue":"10","key":"10.1016\/j.vaccine.2011.08.058_bib0135","doi-asserted-by":"crossref","first-page":"4554","DOI":"10.1128\/IAI.00532-08","article-title":"Immunization with Vibrio cholerae outer membrane vesicles induces protective immunity in mice","volume":"76","author":"Schild","year":"2008","journal-title":"Infect Immun"},{"issue":"44","key":"10.1016\/j.vaccine.2011.08.058_bib0140","doi-asserted-by":"crossref","first-page":"19002","DOI":"10.1073\/pnas.1008843107","article-title":"Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins","volume":"107","author":"Rivera","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"issue":"7","key":"10.1016\/j.vaccine.2011.08.058_bib0145","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1128\/CVI.00039-07","article-title":"Functional and specific antibody responses in adult volunteers in New Zealand who were given one of two different meningococcal serogroup B outer membrane vesicle vaccines","volume":"14","author":"Wedege","year":"2007","journal-title":"Clin Vaccine Immunol"},{"issue":"12","key":"10.1016\/j.vaccine.2011.08.058_bib0150","doi-asserted-by":"crossref","first-page":"e14361","DOI":"10.1371\/journal.pone.0014361","article-title":"Immunospecific responses to bacterial elongation factor Tu during Burkholderia infection and immunization","volume":"5","author":"Nieves","year":"2010","journal-title":"PLoS One"},{"issue":"20","key":"10.1016\/j.vaccine.2011.08.058_bib0155","doi-asserted-by":"crossref","first-page":"5383","DOI":"10.1021\/ac025747h","article-title":"Empirical statistical model to estimate the accuracy of peptide identifications made by MS\/MS and database search","volume":"74","author":"Keller","year":"2002","journal-title":"Anal Chem"},{"key":"10.1016\/j.vaccine.2011.08.058_bib0160","doi-asserted-by":"crossref","first-page":"0017","DOI":"10.1038\/msb4100024","article-title":"A uniform proteomics MS\/MS analysis platform utilizing open XML file formats","volume":"1","author":"Keller","year":"2005","journal-title":"Mol Syst Biol"},{"issue":"4","key":"10.1016\/j.vaccine.2011.08.058_bib0325","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00136-11","article-title":"AuCoin. Identification of circulating bacterial antigens by in vivo microbial antigen discovery","volume":"2","author":"Nuti","year":"2011","journal-title":"mBio"},{"issue":"1","key":"10.1016\/j.vaccine.2011.08.058_bib0170","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.micpath.2009.10.004","article-title":"Differential susceptibility of inbred mouse strains to Burkholderia thailandensis aerosol infection","volume":"48","author":"Morici","year":"2010","journal-title":"Microb Pathog"},{"issue":"14","key":"10.1016\/j.vaccine.2011.08.058_bib0175","doi-asserted-by":"crossref","first-page":"2664","DOI":"10.1016\/j.vaccine.2006.12.006","article-title":"The identification of surface proteins of Burkholderia pseudomallei","volume":"25","author":"Harding","year":"2007","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.vaccine.2011.08.058_bib0180","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1086\/589308","article-title":"Bactericidal antibody responses elicited by a meningococcal outer membrane vesicle vaccine with overexpressed factor H-binding protein and genetically attenuated endotoxin","volume":"198","author":"Koeberling","year":"2008","journal-title":"J Infect Dis"},{"issue":"30","key":"10.1016\/j.vaccine.2011.08.058_bib0330","doi-asserted-by":"crossref","first-page":"4810","DOI":"10.1016\/j.vaccine.2010.04.082","article-title":"Improved OMV vaccine against Neisseria meningitidis using genetically engineered strains and a detergent-free purification process","volume":"28","author":"van de Waterbeemd","year":"2010","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.vaccine.2011.08.058_bib0190","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1046\/j.1365-2249.2000.01386.x","article-title":"Kinetic studies of the production of nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) in macrophages stimulated with Burkholderia pseudomallei endotoxin","volume":"122","author":"Utaisincharoen","year":"2000","journal-title":"Clin Exp Immunol"},{"issue":"1","key":"10.1016\/j.vaccine.2011.08.058_bib0195","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1574-6968.1996.tb08086.x","article-title":"Biological activities of lipopolysaccharide of Burkholderia (Pseudomonas) pseudomallei","volume":"137","author":"Matsuura","year":"1996","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.vaccine.2011.08.058_bib0200","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1084\/jem.113.3.559","article-title":"The susceptibility of mice to bacterial endotoxins","volume":"113","author":"Schaedler","year":"1961","journal-title":"J Exp Med"},{"issue":"4","key":"10.1016\/j.vaccine.2011.08.058_bib0205","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1172\/JCI44261","article-title":"Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice","volume":"121","author":"Prados-Rosales","year":"2011","journal-title":"J Clin Invest"},{"issue":"11","key":"10.1016\/j.vaccine.2011.08.058_bib0210","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1111\/j.1348-0421.1998.tb02346.x","article-title":"Antigenic differences between clinical and environmental isolates of Burkholderia pseudomallei","volume":"42","author":"Sirisinha","year":"1998","journal-title":"Microbiol Immunol"},{"issue":"suppl. 1","key":"10.1016\/j.vaccine.2011.08.058_bib0215","first-page":"146","article-title":"Antigenic heterogeneity of lipopolysaccharide among Burkholderia pseudomallei clinical isolates","volume":"31","author":"Anuntagool","year":"2000","journal-title":"Southeast Asian J Trop Med Public Health"},{"issue":"49","key":"10.1016\/j.vaccine.2011.08.058_bib0220","doi-asserted-by":"crossref","first-page":"19450","DOI":"10.1073\/pnas.0809879105","article-title":"In vitro selection of a neutralization-resistant hepatitis C virus escape mutant","volume":"105","author":"Gal-Tanamy","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"10.1016\/j.vaccine.2011.08.058_bib0225","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1128\/IAI.00105-08","article-title":"Yersinia pestis caf1 variants and the limits of plague vaccine protection","volume":"76","author":"Quenee","year":"2008","journal-title":"Infect Immun"},{"issue":"5","key":"10.1016\/j.vaccine.2011.08.058_bib0230","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1086\/500144","article-title":"Human leukocyte antigen haplotypes in the genetic control of immune response to measles-mumps-rubella vaccine","volume":"193","author":"Ovsyannikova","year":"2006","journal-title":"J Infect Dis"},{"issue":"17\u201318","key":"10.1016\/j.vaccine.2011.08.058_bib0235","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1016\/j.vaccine.2005.01.063","article-title":"MeNZB: a safe and highly immunogenic tailor-made vaccine against the New Zealand Neisseria meningitidis serogroup B disease epidemic strain","volume":"23","author":"Oster","year":"2005","journal-title":"Vaccine"},{"issue":"16","key":"10.1016\/j.vaccine.2011.08.058_bib0240","doi-asserted-by":"crossref","first-page":"3075","DOI":"10.1016\/j.vaccine.2007.01.023","article-title":"Immunogenicity and safety of a strain-specific MenB OMV vaccine delivered to under 5-year olds in New Zealand","volume":"25","author":"Oster","year":"2007","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.vaccine.2011.08.058_bib0245","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1128\/CVI.00230-06","article-title":"Immunogenicity and safety of three doses of a bivalent (B:4:p1.19,15 and B:4:p1.7-2,4) meningococcal outer membrane vesicle vaccine in healthy adolescents","volume":"14","author":"Boutriau","year":"2007","journal-title":"Clin Vaccine Immunol"},{"issue":"5","key":"10.1016\/j.vaccine.2011.08.058_bib0250","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/j.0818-9641.2004.01286.x","article-title":"Aluminium compounds for use in vaccines","volume":"82","author":"Lindblad","year":"2004","journal-title":"Immunol Cell Biol"},{"issue":"3","key":"10.1016\/j.vaccine.2011.08.058_bib0255","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1128\/IAI.73.3.1350-1356.2005","article-title":"CD4+ T cells and toll-like receptors recognize Salmonella antigens expressed in bacterial surface organelles","volume":"73","author":"Bergman","year":"2005","journal-title":"Infect Immun"},{"issue":"7085","key":"10.1016\/j.vaccine.2011.08.058_bib0260","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1038\/nature04596","article-title":"Toll-dependent selection of microbial antigens for presentation by dendritic cells","volume":"440","author":"Blander","year":"2006","journal-title":"Nature"},{"issue":"12","key":"10.1016\/j.vaccine.2011.08.058_bib0265","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1086\/599210","article-title":"Nasal-associated lymphoid tissue and olfactory epithelium as portals of entry for Burkholderia pseudomallei in Murine Melioidosis","volume":"199","author":"Owen","year":"2009","journal-title":"J Infect Dis"},{"issue":"10","key":"10.1016\/j.vaccine.2011.08.058_bib0270","doi-asserted-by":"crossref","first-page":"5820","DOI":"10.1128\/IAI.00331-06","article-title":"Comparison of protective efficacy of subcutaneous versus intranasal immunization of mice with a Brucella melitensis lipopolysaccharide subunit vaccine","volume":"74","author":"Bhattacharjee","year":"2006","journal-title":"Infect Immun"},{"issue":"3","key":"10.1016\/j.vaccine.2011.08.058_bib0275","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1086\/498983","article-title":"Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection","volume":"193","author":"Haque","year":"2006","journal-title":"J Infect Dis"},{"issue":"2","key":"10.1016\/j.vaccine.2011.08.058_bib0280","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1080\/00313029600169853","article-title":"An immunohistochemical method for the diagnosis of melioidosis","volume":"28","author":"Wong","year":"1996","journal-title":"Pathology"},{"issue":"1","key":"10.1016\/j.vaccine.2011.08.058_bib0285","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1365-2559.1995.tb00620.x","article-title":"The histopathology of human melioidosis","volume":"26","author":"Wong","year":"1995","journal-title":"Histopathology"},{"issue":"7","key":"10.1016\/j.vaccine.2011.08.058_bib0290","doi-asserted-by":"crossref","first-page":"3593","DOI":"10.1128\/IAI.67.7.3593-3600.1999","article-title":"Obligatory role of gamma interferon for host survival in a murine model of infection with Burkholderia pseudomallei","volume":"67","author":"Santanirand","year":"1999","journal-title":"Infect Immun"},{"issue":"12","key":"10.1016\/j.vaccine.2011.08.058_bib0295","doi-asserted-by":"crossref","first-page":"8047","DOI":"10.4049\/jimmunol.0801592","article-title":"Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells","volume":"182","author":"Lindenstrom","year":"2009","journal-title":"J Immunol"},{"issue":"7","key":"10.1016\/j.vaccine.2011.08.058_bib0300","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/nm1592","article-title":"Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major","volume":"13","author":"Darrah","year":"2007","journal-title":"Nat Med"},{"issue":"5","key":"10.1016\/j.vaccine.2011.08.058_bib0305","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1056\/NEJMoa0805832","article-title":"Protection against a malaria challenge by sporozoite inoculation","volume":"361","author":"Roestenberg","year":"2009","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.vaccine.2011.08.058_bib0310","doi-asserted-by":"crossref","first-page":"e1000382","DOI":"10.1371\/journal.ppat.1000382","article-title":"Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles","volume":"5","author":"Bomberger","year":"2009","journal-title":"PLoS Pathog"},{"issue":"2","key":"10.1016\/j.vaccine.2011.08.058_bib0315","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.4049\/jimmunol.166.2.1097","article-title":"Bystander activation of CD8+ T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens","volume":"166","author":"Lertmemongkolchai","year":"2001","journal-title":"J Immunol"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X11013041?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X11013041?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,6,22]],"date-time":"2020-06-22T18:32:51Z","timestamp":1592850771000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X11013041"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":63,"journal-issue":{"issue":"46","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["S0264410X11013041"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2011.08.058","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]}}}