{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T13:02:33Z","timestamp":1793710953073,"version":"4.6.1"},"reference-count":170,"publisher":"Elsevier BV","issue":"16","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000277","name":"Department for Environment, Food and Rural Affairs UK","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000277","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Wellcome Trust"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1016\/j.vaccine.2012.02.018","type":"journal-article","created":{"date-parts":[[2012,2,16]],"date-time":"2012-02-16T18:11:29Z","timestamp":1329415889000},"page":"2611-2622","source":"Crossref","is-referenced-by-count":208,"title":["Bovine tuberculosis vaccine research: Historical perspectives and recent advances"],"prefix":"10.1016","volume":"30","author":[{"given":"W. Ray","family":"Waters","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell V.","family":"Palmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryce M.","family":"Buddle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. Martin","family":"Vordermeier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2012.02.018_bib0005","doi-asserted-by":"crossref","first-page":"884","DOI":"10.2105\/AJPH.63.10.884","article-title":"Sharpening the attack on bovine tuberculosis","volume":"63","author":"Roswurm","year":"1973","journal-title":"Am J Public Health"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0010","series-title":"Bovine TB eradication programme for England. Defra publications","year":"2011"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0015","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1017\/S0022050704002955","article-title":"An impossible undertaking: the eradication of bovine tuberculosis in the United States","volume":"64","author":"Olmstead","year":"2004","journal-title":"J Econ Hist"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0020","doi-asserted-by":"crossref","first-page":"816345","DOI":"10.4061\/2011\/816345","article-title":"Bovine tuberculosis and the establishment of an eradication program in the United States: role of veterinarians","volume":"2011","author":"Palmer","year":"2011","journal-title":"Vet Med Int"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0025","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3201\/eid0401.980108","article-title":"Zoonotic tuberculosis due to Mycobacterium bovis in developing countries","volume":"4","author":"Cosivi","year":"1998","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0030","series-title":"Proceedings of the 7th annual meeting of the Interstate Association of Livestock Sanitary Boards, vol. 7","first-page":"7","article-title":"President's annual address","author":"Norton","year":"1904"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0035","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0378-1135(94)90044-2","article-title":"Bovine tuberculosis control and eradication programs in Australia and New Zealand","volume":"40","author":"Tweddle","year":"1994","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0040","series-title":"Bovine tuberculosis overview","year":"2011"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0045","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1136\/vr.136.18.459","article-title":"Control of bovine tuberculosis by vaccination","volume":"136","author":"Newell","year":"1995","journal-title":"Vet Rec"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0050","unstructured":"http:\/\/defra.gov.uk\/animalh\/tb\/stats\/county.htm [last accessed November 2011]."},{"key":"10.1016\/j.vaccine.2012.02.018_bib0055","first-page":"8","article-title":"Approaches to eradication of tuberculosis from wildlife in New Zealand: a revised pest management strategy","volume":"24","author":"Hutchings","year":"2011","journal-title":"Vetscript"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0060","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.vetmic.2005.11.025","article-title":"Advances in understanding disease epidemiology and implications for control and eradication of tuberculosis in livestock: the experience from New Zealand","volume":"112","author":"Ryan","year":"2006","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0070","unstructured":"Flexner S. Immunity in tuberculosis. Annual report of the board of regents of the Smithsonian Institution, 1907. Washington Government Printing Office, 1908;1907:627\u201345."},{"key":"10.1016\/j.vaccine.2012.02.018_bib0075","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1016\/S0140-6736(95)92348-9","article-title":"Variation in protection by BCG: implications of and for heterologous immunity","volume":"346","author":"Fine","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0080","series-title":"The art and science of tuberculosis vaccine development","first-page":"149","article-title":"The history of BCG","author":"Locht","year":"2010"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0085","series-title":"Emil Von Behring: infectious disease, immunology serum therapy","author":"Linton","year":"2005"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0090","series-title":"Bovine tuberculosis","author":"Francis","year":"1947"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0095","series-title":"Tuberculosis in animals and man","author":"Francis","year":"1958"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0100","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3733\/hilg.v04n12p307","article-title":"Vaccination of calves against tuberculosis with Calmette\u2013Guerin culture, BCG","volume":"4","author":"Haring","year":"1930","journal-title":"Hilgardia"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0105","first-page":"553","article-title":"New research experiments on vaccination of cattle against tuberculosis","volume":"34","author":"Calmette","year":"1920","journal-title":"Ann Inst Pasteur"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0110","first-page":"371","article-title":"Vaccination of cattle against tuberculosis and new method of prophylaxis of the bovine tuberculosis","volume":"38","author":"Calmette","year":"1924","journal-title":"Ann Inst Pasteur"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0115","first-page":"183","article-title":"Vaccination of cattle in herds infected with TB with the \u2018strain P\u2019 tubercle bacillus described by Gr\u00e4ub","volume":"26","author":"Schellner","year":"1955","journal-title":"Vet Bull"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0120","first-page":"105","article-title":"Results of BCG vaccination in cattle in Bavaria","volume":"27","author":"Rolle","year":"1956","journal-title":"Vet Bull"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0125","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S0007-1935(17)36634-4","article-title":"A second experiment to challenge the resistance to tuberculosis in BCG vaccinated cattle in Malawi","volume":"128","author":"Ellwood","year":"1972","journal-title":"Br Vet J"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0130","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/S0007-1935(17)33946-5","article-title":"Tuberculin reactions in BCG-vaccinated cattle","volume":"133","author":"Moodie","year":"1977","journal-title":"Br Vet J"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0135","series-title":"Proceedings of Kazan Veterinary Institute, vol. 60","first-page":"62","article-title":"Eradicating tuberculosis from large cattle breeding complexes by using BCG vaccine, Veterinary Institute, Development of Efficient Prophylactic and Treatment Methods for Animal Infectious Diseases","author":"Sibgatullin","year":"1982"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0140","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0007-1935(17)45652-1","article-title":"Vaccination of cattle with BCG","volume":"114","author":"Doyle","year":"1958","journal-title":"Br Vet J"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0145","first-page":"799","article-title":"Research on Bacillus Calmette\u2013Gu\u00e9rin and experimental vaccination against bovine tuberculosis","volume":"73","author":"Watson","year":"1928","journal-title":"J Am Vet Med Assoc"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0150","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/S0007-1935(17)33991-X","article-title":"Incidence of tuberculosis in BCG vaccinated and control cattle in relation to age distribution in Malawi","volume":"133","author":"Berggren","year":"1977","journal-title":"Br Vet J"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0155","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/S0007-1935(17)31792-X","article-title":"Field experiment with BCG vaccine in Malawi","volume":"137","author":"Berggren","year":"1981","journal-title":"Br Vet J"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0160","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1017\/S0022172400014303","article-title":"Studies on the vaccination of cattle as a measure against infection with tuberculosis with the living vole acid-fast bacillus","volume":"4","author":"Young","year":"1949","journal-title":"J Hyg (Lond)"},{"issue":"1","key":"10.1016\/j.vaccine.2012.02.018_bib0165","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/0034-5288(95)90023-3","article-title":"Protection of cattle from bovine tuberculosis by vaccination with BCG by the respiratory or subcutaneous route, but not by vaccination with killed Mycobacterium vaccae","volume":"59","author":"Buddle","year":"1995","journal-title":"Res Vet Sci"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0170","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0007-1935(17)50732-0","article-title":"Field trials with BCG for immunisation of calves against tuberculosis","volume":"109","author":"Glover","year":"1953","journal-title":"Br Vet J"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0175","doi-asserted-by":"crossref","first-page":"112","DOI":"10.20506\/rst.20.1.1276","article-title":"Vaccination of animals against Mycobacterium bovis","volume":"20","author":"Skinner","year":"2001","journal-title":"Rev Sci Tech"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0180","series-title":"In The art and science of tuberculosis vaccine development","first-page":"401","article-title":"Development of cattle tuberculosis vaccines","year":"2010"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0185","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.vetmic.2011.02.021","article-title":"Update on vaccination of cattle and wildlife populations against tuberculosis","volume":"151","author":"Buddle","year":"2011","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0190","doi-asserted-by":"crossref","first-page":"6411","DOI":"10.1128\/IAI.71.11.6411-6419.2003","article-title":"Revaccination of neonatal calves with Mycobacterium bovis BCG reduces the level of protection against bovine tuberculosis induced by a single vaccination","volume":"71","author":"Buddle","year":"2003","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0195","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1586\/14760584.4.6.891","article-title":"Vaccines for bovine tuberculosis: current views and future prospects","volume":"4","author":"Hope","year":"2005","journal-title":"Expert Rev Vaccines"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0200","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.vetimm.2007.04.005","article-title":"Vaccination of cattle with Danish and Pasteur strains of Mycobacterium bovis BCG induce different levels of IFNgamma post-vaccination, but induce similar levels of protection against bovine tuberculosis","volume":"118","author":"Wedlock","year":"2007","journal-title":"Vet Immunol Immunopathol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0205","doi-asserted-by":"crossref","first-page":"3581","DOI":"10.1016\/j.vaccine.2005.01.150","article-title":"Effect of oral vaccination of cattle with lipid-formulated BCG on immune responses and protection against bovine tuberculosis","volume":"23","author":"Buddle","year":"2005","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0210","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.tube.2008.01.005","article-title":"Vaccination of cattle with Mycobacterium bovis BCG by a combination of systemic and oral routes","volume":"88","author":"Buddle","year":"2008","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0215","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.tube.2011.07.001","article-title":"Low oral BCG doses fail to protect cattle against an experimental challenge with Mycobacterium bovis","volume":"91","author":"Buddle","year":"2011","journal-title":"Tuberculosis (Edinb)"},{"issue":"1","key":"10.1016\/j.vaccine.2012.02.018_bib0220","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.rvsc.2009.05.022","article-title":"Field evaluation of the protective efficacy of Mycobacterium bovis BCG vaccine against bovine tuberculosis","volume":"88","author":"Lopez-Valencia","year":"2010","journal-title":"Res Vet Sci"},{"issue":"10","key":"10.1016\/j.vaccine.2012.02.018_bib0225","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1128\/CVI.00222-10","article-title":"Field evaluation of the efficacy of Mycobacterium bovis bacillus Calmette\u2013Guerin against bovine tuberculosis in neonatal calves in Ethiopia","volume":"17","author":"Ameni","year":"2010","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0230","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.tube.2007.11.010","article-title":"Adverse reactions to Mycobacterium bovis bacille Calmette\u2013Gu\u00e9rin (BCG) vaccination against tuberculosis in humans, veterinary animals and wildlife species","volume":"88","author":"Murphy","year":"2008","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0235","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1136\/vr.95.24.552","article-title":"Tuberculosis in wild badgers in Gloucestershire: epidemiology","volume":"95","author":"Muirhead","year":"1974","journal-title":"Vet Rec"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0240","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1017\/S0950268800056624","article-title":"Mycobacterium bovis in the European badger (Meles meles): epidemiological findings in tuberculous badgers from a naturally infected population","volume":"111","author":"Clifton-Hadley","year":"1993","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0245","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.prevetmed.2004.10.009","article-title":"The impact of badger removal on the control of tuberculosis in cattle herds in Ireland","volume":"67","author":"Griffin","year":"2005","journal-title":"Prev Vet Med"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0250","doi-asserted-by":"crossref","first-page":"749","DOI":"10.7589\/0090-3558-33.4.749","article-title":"Bovine tuberculosis in free-ranging white-tailed deer from Michigan","volume":"33","author":"Schmitt","year":"1997","journal-title":"J Wildl Dis"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0255","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/j.1749-6632.2002.tb04390.x","article-title":"Bovine tuberculosis in Michigan wildlife and livestock","volume":"969","author":"Schmitt","year":"2002","journal-title":"Ann NY Acad Sci"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0260","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.vetmic.2005.11.014","article-title":"Managing the wildlife reservoir of Mycobacterium bovis: the Michigan USA, experience","volume":"112","author":"O\u2019Brien","year":"2006","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0265","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1099\/00207713-20-3-273","article-title":"Mycobacterium bovis Nom. Nov.","volume":"20","author":"Karlson","year":"1970","journal-title":"Int J Syst Bacteriol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0270","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1080\/00480169.2006.36612","article-title":"Trends in the incidence of tuberculosis in possums and livestock, associated with differing control intensities applied to possum populations","volume":"54","author":"Coleman","year":"2006","journal-title":"NZ Vet J"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0275","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1051\/vetres:2007003","article-title":"A descriptive spatial analysis of bovine tuberculosis in intensively controlled cattle farms in New Zealand","volume":"38","author":"Porphyre","year":"2007","journal-title":"Vet Res"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vetmic.2007.10.002","article-title":"Evidence of the role of European wild boar as a reservoir of Mycobacterium tuberculosis complex","volume":"127","author":"Naranjo","year":"2008","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0285","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1136\/vr.152.25.779","article-title":"Pathology of bovine tuberculosis in the European wild boar (Sus scrofa)","volume":"152","author":"Gortazar","year":"2003","journal-title":"Vet Rec"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0290","doi-asserted-by":"crossref","first-page":"e2776","DOI":"10.1371\/journal.pone.0002776","article-title":"Bovine tuberculosis in Do\u00f1ana Biosphere Reserve: the role of wild ungulates as disease reservoirs in the last Iberian lynx strongholds","volume":"3","author":"Gort\u00e1zar","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0295","first-page":"497","article-title":"The role of wildlife in emerging and re-emerging zoonoses","volume":"23","author":"Bengis","year":"2004","journal-title":"Rev Sci Tech"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0300","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.vetmic.2005.11.035","article-title":"Wildlife tuberculosis in South African conservation areas: implications and challenges","volume":"112","author":"Michel","year":"2006","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0305","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.vetmic.2005.11.027","article-title":"Progress in the development of tuberculosis vaccines for cattle and wildlife","volume":"112","author":"Buddle","year":"2006","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0310","doi-asserted-by":"crossref","first-page":"e206","DOI":"10.1111\/j.1863-2378.2010.01329.x","article-title":"Persistence of Mycobacterium bovis Bacillus Calmette\u2013Gu\u00e9rin in white-tailed deer (Odocoileus virginianus) after oral or parenteral vaccination","volume":"57","author":"Palmer","year":"2010","journal-title":"Zoonoses Public Health"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0315","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1863-2378.2008.01198.x","article-title":"Vaccination with Mycobacterium bovis BCG strains Danish and Pasteur in white-tailed deer (Odocoileus virginianus) experimentally challenged with Mycobacterium bovis","volume":"56","author":"Palmer","year":"2009","journal-title":"Zoonoses Public Health"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0320","unstructured":"Saker L, Lee K, Cannito B, Gilmore A, Campbell-Lendrum D. Globalization and infectious diseases. A review of the linkages. UNICEF\/UNDP\/World Bank\/WHO Special Programme for Research and Training in Tropical Diseases (TDR). Special Topics No. 3. Geneva; 2004."},{"key":"10.1016\/j.vaccine.2012.02.018_bib0325","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.vetmic.2011.02.039","article-title":"Bovine tuberculosis in Europe from the perspective of an officially tuberculosis free country: trade, surveillance and diagnostics","volume":"151","author":"Schiller","year":"2011","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0330","unstructured":"COAG 2005\/2006, The COMMITTEE ON AGRICULTURE. Globalizing livestock sector: impact of changing markets. Rome; 13\u201316 April 2005. http:\/\/www.fao.org\/docrep\/meeting\/009\/j4196e.htm [last accessed November 2011]."},{"key":"10.1016\/j.vaccine.2012.02.018_bib0335","unstructured":"www.usaha.org\/Portals\/6\/Publications\/2009_TB_Report.pdf [last accessed December 2011]."},{"key":"10.1016\/j.vaccine.2012.02.018_bib0340","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/CDLI.6.1.1-5.1999","article-title":"Differentiation between Mycobacterium bovis BCG-vaccinated and M. bovis-infected cattle by using recombinant mycobacterial antigens","volume":"6","author":"Buddle","year":"1999","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0345","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1128\/CDLI.6.5.675-682.1999","article-title":"Development of diagnostic reagents to differentiate between Mycobacterium bovis BCG vaccination and M. bovis infection in cattle","volume":"6","author":"Vordermeier","year":"1999","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0350","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.vetmic.2011.02.020","article-title":"Mycobacterium bovis antigens for the differential diagnosis of vaccinated and infected cattle","volume":"151","author":"Vordermeier","year":"2011","journal-title":"Vet Microbiol"},{"issue":"33","key":"10.1016\/j.vaccine.2012.02.018_bib0355","doi-asserted-by":"crossref","first-page":"5453","DOI":"10.1016\/j.vaccine.2011.05.057","article-title":"Lack of correlation between BCG-induced tuberculin skin test sensitisation and protective immunity in cattle","volume":"29","author":"Whelan","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0360","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/S0140-6736(00)02742-2","article-title":"Specific immune-based diagnosis of tuberculosis","volume":"356","author":"Andersen","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0365","doi-asserted-by":"crossref","first-page":"3394","DOI":"10.1128\/JB.182.12.3394-3399.2000","article-title":"A point mutation in the mma3 gene is responsible for impaired methoxymycolic acid production in Mycobacterium bovis BCG strains obtained after 1927","volume":"182","author":"Behr","year":"2000","journal-title":"J Bacteriol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0370","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S1473-3099(02)00182-2","article-title":"BCG\u2014different strains, different vaccines?","volume":"2","author":"Behr","year":"2002","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0375","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2001-2-10-research0044","article-title":"The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria","volume":"2","author":"Gey Van Pittius","year":"2001","journal-title":"Genome Biol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0380","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1128\/jb.178.5.1274-1282.1996","article-title":"Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis","volume":"178","author":"Mahairas","year":"1996","journal-title":"J Bacteriol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0385","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1046\/j.1365-2958.2002.03237.x","article-title":"Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti","volume":"46","author":"Pym","year":"2002","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0390","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.vaccine.2008.12.018","article-title":"Efficacy and immunogenicity of Mycobacterium bovis DeltaRD1 against aerosol M. bovis infection in neonatal calves","volume":"27","author":"Waters","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0395","doi-asserted-by":"crossref","first-page":"3176","DOI":"10.1128\/JCM.00420-10","article-title":"Development of a skin test for bovine tuberculosis for differentiating infected from vaccinated animals","volume":"48","author":"Whelan","year":"2010","journal-title":"J Clin Microbiol"},{"issue":"7","key":"10.1016\/j.vaccine.2012.02.018_bib0400","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1586\/erv.11.22","article-title":"DIVA reagents for bovine tuberculosis vaccines in cattle","volume":"10","author":"Vordermeier","year":"2011","journal-title":"Expert Rev Vaccines"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0405","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1128\/IAI.65.7.2587-2592.1997","article-title":"Predominant recognition of the ESAT-6 protein in the first phase of interferon with Mycobacterium bovis in cattle","volume":"65","author":"Pollock","year":"1997","journal-title":"Infect Immun"},{"issue":"8","key":"10.1016\/j.vaccine.2012.02.018_bib0410","doi-asserted-by":"crossref","first-page":"3719","DOI":"10.1128\/JCM.41.8.3719-3728.2003","article-title":"Genomic approach to identification of Mycobacterium bovis diagnostic antigens in cattle","volume":"41","author":"Aagaard","year":"2003","journal-title":"J Clin Microbiol"},{"issue":"9","key":"10.1016\/j.vaccine.2012.02.018_bib0415","doi-asserted-by":"crossref","first-page":"3932","DOI":"10.1128\/IAI.00150-08","article-title":"Screening of highly expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for the Mycobacterium tuberculosis complex","volume":"76","author":"Sidders","year":"2008","journal-title":"Infect Immun"},{"issue":"6","key":"10.1016\/j.vaccine.2012.02.018_bib0420","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1111\/j.1365-2958.2005.04800.x","article-title":"A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis","volume":"57","author":"MacGurn","year":"2005","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0425","doi-asserted-by":"crossref","first-page":"5730","DOI":"10.1073\/pnas.1015153108","article-title":"Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection","volume":"108","author":"Millington","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0430","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1128\/IAI.01246-09","article-title":"Screening of predicted secreted antigens from Mycobacterium bovis reveals the immunodominance of the ESAT-6 protein family","volume":"78","author":"Jones","year":"2010","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0435","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1128\/CVI.00261-10","article-title":"Screening of predicted secreted antigens from Mycobacterium bovis identifies potential novel differential diagnostic reagents","volume":"17","author":"Jones","year":"2010","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0440","doi-asserted-by":"crossref","first-page":"e21371","DOI":"10.1371\/journal.pone.0021371","article-title":"Immune responses to the Enduring Hypoxia Response antigen Rv0188 are preferentially detected in Mycobacterium bovis infected cattle with low pathology","volume":"6","author":"Jones","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0445","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1128\/JCM.41.5.1856-1860.2003","article-title":"Specific delayed-type hypersensitivity responses to ESAT-6 identify tuberculosis-infected cattle","volume":"41","author":"Pollock","year":"2003","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0450","doi-asserted-by":"crossref","first-page":"6420","DOI":"10.1128\/IAI.71.11.6420-6425.2003","article-title":"Modulation of the bovine delayed-type hypersensitivity responses to defined mycobacterial antigens by a synthetic bacterial lipopeptide","volume":"71","author":"Whelan","year":"2003","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0455","doi-asserted-by":"crossref","unstructured":"Jones GJ, Whelan AO, Clifford D, Coad M, Vordermeier HM. Improved skin test for differential diagnosis of bovine tuberculosis by the addition of Rv3020c-derived peptides. Clin Vaccine Immunol; 2012 [Epub ahead of print].","DOI":"10.1128\/CVI.00024-12"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0460","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1128\/CVI.00377-10","article-title":"Simultaneous measurement of antigen-stimulated interleukin-1 beta and gamma interferon production enhances test sensitivity for the detection of Mycobacterium bovis infection in cattle","volume":"17","author":"Jones","year":"2010","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0465","doi-asserted-by":"crossref","unstructured":"Aranday Cortes E, Hogarth P, Kaveh D, Whelan A, Villareal-Ramos B, Lalvani A, et al. Transcriptional profiling of disease-induced host responses in bovine tuberculosis and the identification of potential diagnostic biomarkers. PLoS One; in press.","DOI":"10.1371\/journal.pone.0030626"},{"issue":"4","key":"10.1016\/j.vaccine.2012.02.018_bib0470","first-page":"205","article-title":"Bovine tuberculosis: a review of current and emerging diagnostic techniques in view of their relevance for disease control and eradication","volume":"57","author":"Schiller","year":"2010","journal-title":"Transbound Emerg Dis"},{"issue":"6","key":"10.1016\/j.vaccine.2012.02.018_bib0475","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1054\/tube.2002.0341","article-title":"Aerosol delivery of virulent Mycobacterium bovis to cattle","volume":"82","author":"Palmer","year":"2002","journal-title":"Tuberculosis (Edinb)"},{"issue":"5","key":"10.1016\/j.vaccine.2012.02.018_bib0480","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1080\/00480169.1994.35814","article-title":"Experimental Mycobacterium bovis infection of cattle: effect of dose of M. bovis and pregnancy on immune responses and distribution of lesions","volume":"42","author":"Buddle","year":"1994","journal-title":"NZ Vet J"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2012.02.018_bib0485","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.tube.2004.09.003","article-title":"Cattle as a model for development of vaccines against human tuberculosis","volume":"85","author":"Buddle","year":"2005","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0490","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1586\/erv.10.112","article-title":"Tuberculosis vaccines for cattle: the way forward","volume":"9","author":"Buddle","year":"2010","journal-title":"Expert Rev Vaccines"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0495","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1016\/S0140-6736(10)60393-5","article-title":"New vaccines for tuberculosis","volume":"375","author":"Kaufmann","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0500","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1128\/CVI.05505-11","article-title":"Vaccines displaying mycobacterial proteins on biopolyester beads stimulate cellular immunity and induce protection against tuberculosis","volume":"19","author":"Parlane","year":"2011","journal-title":"Clin Vaccine Immunol"},{"issue":"8","key":"10.1016\/j.vaccine.2012.02.018_bib0505","doi-asserted-by":"crossref","first-page":"3364","DOI":"10.1128\/IAI.00287-09","article-title":"Viral booster vaccines improve Mycobacterium bovis BCG-induced protection against bovine tuberculosis","volume":"77","author":"Vordermeier","year":"2009","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0510","doi-asserted-by":"crossref","first-page":"e27477","DOI":"10.1371\/journal.pone.0027477","article-title":"Simultaneous immunization against tuberculosis","volume":"6","author":"Tchilian","year":"2011","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.vaccine.2012.02.018_bib0515","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.1128\/IAI.67.5.2172-2177.1999","article-title":"Immune responses induced in cattle by virulent and attenuated Mycobacterium bovis strains: correlation of delayed-type hypersensitivity with ability of strains to grow in macrophages","volume":"67","author":"Wedlock","year":"1999","journal-title":"Infect Immun"},{"issue":"3\u20134","key":"10.1016\/j.vaccine.2012.02.018_bib0520","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0165-2427(02)00049-1","article-title":"New generation vaccines and delivery systems for control of bovine tuberculosis in cattle and wildlife","volume":"87","author":"Buddle","year":"2002","journal-title":"Vet Immunol Immunopathol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0525","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.1371\/journal.ppat.0030110","article-title":"Mycobacterium tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells","volume":"3","author":"Velmurugan","year":"2007","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0530","unstructured":"Jalapathy KV. NlaA: a protein of Mycobacterium tuberculosis mediates evasion of host cell apoptosis. Dissertation. New York: Yeshiva University; 2006."},{"key":"10.1016\/j.vaccine.2012.02.018_bib0535","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.vaccine.2009.09.087","article-title":"Recombinant pro-apoptotic Mycobacterium tuberculosis generates CD8+ T cell responses against human immunodeficiency virus type 1 Env and M. tuberculosis in neonatal mice","volume":"28","author":"Ranganathan","year":"2009","journal-title":"Vaccine"},{"issue":"25","key":"10.1016\/j.vaccine.2012.02.018_bib0540","doi-asserted-by":"crossref","first-page":"13853","DOI":"10.1073\/pnas.250480397","article-title":"Recombinant bacillus Calmette\u2013Guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model","volume":"97","author":"Horwitz","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"issue":"10","key":"10.1016\/j.vaccine.2012.02.018_bib0545","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1038\/nm.2420","article-title":"A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis","volume":"17","author":"Sweeney","year":"2011","journal-title":"Nat Med"},{"issue":"5","key":"10.1016\/j.vaccine.2012.02.018_bib0550","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1586\/14760584.7.5.635","article-title":"Tuberculosis: vaccines in the pipeline","volume":"7","author":"Ly","year":"2008","journal-title":"Expert Rev Vaccines"},{"issue":"2","key":"10.1016\/j.vaccine.2012.02.018_bib0555","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.vaccine.2007.11.005","article-title":"Evidence for enhanced central memory priming by live Mycobacterium bovis BCG vaccine in comparison with killed BCG formulations","volume":"26","author":"Whelan","year":"2008","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0560","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1002\/eji.201040731","article-title":"Polyfunctional T cells in human tuberculosis","volume":"40","author":"Wilkinson","year":"2010","journal-title":"Eur J Immunol"},{"issue":"12","key":"10.1016\/j.vaccine.2012.02.018_bib0565","doi-asserted-by":"crossref","first-page":"e29194","DOI":"10.1371\/journal.pone.0029194","article-title":"Development of an antibody to bovine IL-2 reveals multifunctional CD4 TEM cells in cattle naturally infected with bovine tuberculosis","volume":"6","author":"Whelan","year":"2011","journal-title":"PLoS One"},{"issue":"9315","key":"10.1016\/j.vaccine.2012.02.018_bib0570","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1016\/S0140-6736(02)08353-8","article-title":"CG-induced increase in interferon-gamma response to mycobacterial antigens and efficacy of BCG vaccination in Malawi and the UK: two randomised controlled studies","volume":"359","author":"Black","year":"2002","journal-title":"Lancet"},{"issue":"7\u20138","key":"10.1016\/j.vaccine.2012.02.018_bib0575","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/S0264-410X(01)00436-4","article-title":"Influence of sensitisation to environmental mycobacteria on subsequent vaccination against bovine tuberculosis","volume":"20","author":"Buddle","year":"2002","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.vaccine.2012.02.018_bib0580","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1111\/j.1365-2249.2005.02882.x","article-title":"Exposure to Mycobacterium avium induces low-level protection from Mycobacterium bovis infection but compromises diagnosis of disease in cattle","volume":"141","author":"Hope","year":"2005","journal-title":"Clin Exp Immunol"},{"issue":"6","key":"10.1016\/j.vaccine.2012.02.018_bib0585","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.1128\/IAI.70.6.3026-3032.2002","article-title":"Correlation of ESAT-6-specific gamma interferon production with pathology in cattle following Mycobacterium bovis BCG vaccination against experimental bovine tuberculosis","volume":"70","author":"Vordermeier","year":"2002","journal-title":"Infect Immun"},{"issue":"45","key":"10.1016\/j.vaccine.2012.02.018_bib0590","doi-asserted-by":"crossref","first-page":"7832","DOI":"10.1016\/j.vaccine.2007.08.029","article-title":"Failure of a Mycobacterium tuberculosis DeltaRD1 DeltapanCD double deletion mutant in a neonatal calf aerosol M. bovis challenge model: comparisons to responses elicited by M. bovis bacille Calmette Guerin","volume":"25","author":"Waters","year":"2007","journal-title":"Vaccine"},{"issue":"10","key":"10.1016\/j.vaccine.2012.02.018_bib0595","doi-asserted-by":"crossref","first-page":"6332","DOI":"10.4049\/jimmunol.174.10.6332","article-title":"Exchanging ESAT6 with TB10.4 in an Ag85B fusion molecule-based tuberculosis subunit vaccine: efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy","volume":"174","author":"Dietrich","year":"2005","journal-title":"J Immunol"},{"issue":"5","key":"10.1016\/j.vaccine.2012.02.018_bib0600","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1128\/IAI.72.5.2462-2467.2004","article-title":"Association of tuberculin-boosted antibody responses with pathology and cell-mediated immunity in cattle vaccinated with Mycobacterium bovis BCG and infected with M. bovis","volume":"72","author":"Lyashchenko","year":"2004","journal-title":"Infect Immunol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0605","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1128\/CVI.00061-06","article-title":"Early antibody responses to experimental Mycobacterium bovis infection of cattle","volume":"13","author":"Waters","year":"2006","journal-title":"Clin Vaccine Immunol"},{"issue":"1","key":"10.1016\/j.vaccine.2012.02.018_bib0610","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1128\/IAI.71.1.317-326.2003","article-title":"Expression of L-Selectin (CD62L) CD44, and CD25 on activated bovine T cells","volume":"71","author":"Waters","year":"2003","journal-title":"Infect Immun"},{"issue":"5","key":"10.1016\/j.vaccine.2012.02.018_bib0615","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S1472-9792(03)00002-7","article-title":"Mycobacterium bovis bacille Calmette\u2013Guerin vaccination of cattle: activation of bovine CD4+ and gamma delta TCR+ cells and modulation by 1,25-dihydroxyvitamin D3","volume":"83","author":"Waters","year":"2003","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0620","series-title":"Fourth international symposium on animal functional genomics","article-title":"Transcriptome analysis of stimulated PBMC from Mycobacterium bovis infected cattle","author":"Thacker","year":"2011"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2012.02.018_bib0625","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.vetimm.2005.01.002","article-title":"Vaccination of cattle with Mycobacterium bovis culture filtrate proteins and CpG oligodeoxynucleotides induces protection against bovine tuberculosis","volume":"106","author":"Wedlock","year":"2005","journal-title":"Vet Immunol Immunopathol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0630","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1136\/vr.118.26.718","article-title":"Pulmonary lesions and Mycobacterium bovis excretion from the respiratory tract of tuberculin reacting cattle","volume":"118","author":"McIlroy","year":"1986","journal-title":"Vet Rec"},{"issue":"6","key":"10.1016\/j.vaccine.2012.02.018_bib0635","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.vaccine.2004.07.019","article-title":"CD80 and CD86, but not CD154, augment DNA vaccine-induced protection in experimental bovine tuberculosis","volume":"23","author":"Maue","year":"2004","journal-title":"Vaccine"},{"issue":"11","key":"10.1016\/j.vaccine.2012.02.018_bib0640","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1128\/CVI.05323-11","article-title":"Experimental model of tuberculosis in the domestic goat after endobronchial infection with Mycobacterium caprae","volume":"18","author":"de Val P\u00e9rez","year":"2011","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0645","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.jcpa.2005.05.001","article-title":"Advanced granulomatous lesions in Mycobacterium bovis-infected cattle are associated with increased expression of type I procollagen, gamma delta (WC1+) T cells and CD 68+ cells","volume":"133","author":"Wangoo","year":"2005","journal-title":"J Comp Pathol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0650","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1007\/s10344-010-0483-9","article-title":"Specificity and success of oral bait delivery to Eurasian wild boar in Mediterranean woodland habitats","volume":"57","author":"Ballesteros","year":"2011","journal-title":"Eur J Wildl Res"},{"issue":"3","key":"10.1016\/j.vaccine.2012.02.018_bib0655","doi-asserted-by":"crossref","first-page":"754","DOI":"10.7589\/0090-3558-45.3.754","article-title":"Lipid-formulated bcg as an oral-bait vaccine for tuberculosis: vaccine stability, efficacy, and palatability to brushtail possums (Trichosurus vulpecula) in New Zealand","volume":"45","author":"Cross","year":"2009","journal-title":"J Wildl Dis"},{"issue":"9","key":"10.1016\/j.vaccine.2012.02.018_bib0660","doi-asserted-by":"crossref","first-page":"e24905","DOI":"10.1371\/journal.pone.0024905","article-title":"Protection against tuberculosis in Eurasian wild boar vaccinated with heat-inactivated Mycobacterium bovis","volume":"6","author":"Garrido","year":"2011","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.vaccine.2012.02.018_bib0665","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1054\/tube.2001.0318","article-title":"Increased protection against bovine tuberculosis in the brushtail possum (Trichosurus vulpecula) when BCG is administered with killed Mycobacterium vaccae","volume":"82","author":"Skinner","year":"2002","journal-title":"Tuberculosis (Edinb)"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2012.02.018_bib0670","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.vetmic.2011.02.031","article-title":"Newly attenuated Mycobacterium bovis mutants as vaccines against bovine tuberculosis, particularly for possums","volume":"151","author":"Collins","year":"2011","journal-title":"Vet Microbiol"},{"issue":"5","key":"10.1016\/j.vaccine.2012.02.018_bib0675","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1080\/00480169.2005.36564","article-title":"Oral vaccination of brushtail possums (Trichosurus vulpecula) with BCG: immune responses, persistence of BCG in lymphoid organs and excretion in faeces","volume":"53","author":"Wedlock","year":"2005","journal-title":"NZ Vet J"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0680","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/0007-1935(89)90075-4","article-title":"Interactions between cattle and badgers at pasture with reference to bovine tuberculosis transmission","volume":"145","author":"Benham","year":"1989","journal-title":"Br Vet J"},{"issue":"1669","key":"10.1016\/j.vaccine.2012.02.018_bib0685","doi-asserted-by":"crossref","first-page":"2987","DOI":"10.1098\/rspb.2009.0414","article-title":"Oral vaccination reduces the incidence of tuberculosis in free-living brushtail possums","volume":"276","author":"Tompkins","year":"2009","journal-title":"Proc Biol Sci"},{"issue":"1713","key":"10.1016\/j.vaccine.2012.02.018_bib0690","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1098\/rspb.2010.1953","article-title":"Bacillus Calmette\u2013Gu\u00e9rin vaccination reduces the severity and progression of tuberculosis in badgers","volume":"278","author":"Chambers","year":"2011","journal-title":"Proc Biol Sci"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0695","series-title":"Badger vaccine deployment project","author":"FERA","year":"2010"},{"issue":"5","key":"10.1016\/j.vaccine.2012.02.018_bib0700","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1586\/erv.11.28","article-title":"Tuberculosis vaccines in clinical trials","volume":"10","author":"Rowland","year":"2011","journal-title":"Expert Rev Vaccines"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0705","first-page":"625","article-title":"Experimental research on the body's defense against the tuberculosis infection","volume":"25","author":"Calmette","year":"1911","journal-title":"Ann Inst Pasteur (Paris)"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0710","author":"Buxton","year":"1939"},{"issue":"2","key":"10.1016\/j.vaccine.2012.02.018_bib0715","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1046\/j.1365-2249.2002.01987.x","article-title":"Exposure to Mycobacterium avium primes the immune system of calves for vaccination with Mycobacterium bovis BCG","volume":"130","author":"Howard","year":"2002","journal-title":"Clin Exp Immunol"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2012.02.018_bib0720","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.tube.2004.09.007","article-title":"The efficacy of live tuberculosis vaccines after presensitization with Mycobacterium avium","volume":"85","author":"de Lisle","year":"2005","journal-title":"Tuberculosis (Edinb)"},{"issue":"4","key":"10.1016\/j.vaccine.2012.02.018_bib0725","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.tube.2007.12.002","article-title":"Consequence of prior exposure to environmental mycobacteria on BCG vaccination and diagnosis of tuberculosis infection","volume":"88","author":"Thom","year":"2008","journal-title":"Tuberculosis (Edinb)"},{"issue":"1","key":"10.1016\/j.vaccine.2012.02.018_bib0730","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1365-2249.2005.02668.x","article-title":"Vaccination of neonatal calves with Mycobacterium bovis BCG induces protection against intranasal challenge with virulent M. bovis","volume":"139","author":"Hope","year":"2005","journal-title":"Clin Exp Immunol"},{"issue":"1\u20133","key":"10.1016\/j.vaccine.2012.02.018_bib0735","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.vetimm.2008.10.312","article-title":"The calf model of immunity for development of a vaccine against tuberculosis","volume":"128","author":"Endsley","year":"2009","journal-title":"Vet Immunol Immunopathol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0740","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1439-0442.1956.tb00119.x","article-title":"Further results with modified BCG vaccination of calves","volume":"3","author":"Fritzsche","year":"1956","journal-title":"Zentralbl Veterin\u00e4rmed"},{"issue":"7","key":"10.1016\/j.vaccine.2012.02.018_bib0745","doi-asserted-by":"crossref","first-page":"4441","DOI":"10.1128\/IAI.73.7.4441-4444.2005","article-title":"The order of prime\u2013boost vaccination of neonatal calves with Mycobacterium bovis BCG and a DNA vaccine encoding mycobacterial proteins Hsp65 Hsp70, and Apa is not critical for enhancing protection against bovine tuberculosis","volume":"73","author":"Skinner","year":"2005","journal-title":"Infect Immun"},{"issue":"9","key":"10.1016\/j.vaccine.2012.02.018_bib0750","doi-asserted-by":"crossref","first-page":"4901","DOI":"10.1128\/IAI.71.9.4901-4907.2003","article-title":"A DNA prime-Mycobacterium bovis BCG boost vaccination strategy for cattle induces protection against bovine tuberculosis","volume":"71","author":"Skinner","year":"2003","journal-title":"Infect Immun"},{"issue":"8","key":"10.1016\/j.vaccine.2012.02.018_bib0755","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1089\/dna.2006.25.438","article-title":"A combined DNA vaccine-prime BCG-boost strategy results in better protection against Mycobacterium bovis challenge","volume":"25","author":"Cai","year":"2006","journal-title":"DNA Cell Biol"},{"issue":"6","key":"10.1016\/j.vaccine.2012.02.018_bib0760","doi-asserted-by":"crossref","first-page":"3540","DOI":"10.1128\/IAI.73.6.3540-3546.2005","article-title":"Vaccination of cattle with a CpG oligodeoxynucleotide-formulated mycobacterial protein vaccine and Mycobacterium bovis BCG induces levels of protection against bovine tuberculosis superior to those induced by vaccination with BCG alone","volume":"73","author":"Wedlock","year":"2005","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.vaccine.2012.02.018_bib0765","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/0034-5288(95)90095-0","article-title":"Effectiveness of BCG vaccination in protecting possums against bovine tuberculosis","volume":"58","author":"Aldwell","year":"1995","journal-title":"Res Vet Sci"},{"issue":"1","key":"10.1016\/j.vaccine.2012.02.018_bib0770","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/S0264-410X(03)00539-5","article-title":"Oral vaccination with Mycobacterium bovis BCG in a lipid formulation induces resistance to pulmonary tuberculosis in brushtail possums","volume":"22","author":"Aldwell","year":"2003","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0775","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0034-5288(02)00038-3","article-title":"The efficacy of bacille Calmette\u2013Guerin vaccine in wild brushtail possums (Trichosurus vulpecula)","volume":"73","author":"Corner","year":"2002","journal-title":"Res Vet Sci"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0780","doi-asserted-by":"crossref","first-page":"6265","DOI":"10.1016\/j.vaccine.2010.06.120","article-title":"Oral vaccination of badgers (Meles meles) with BCG and protective immunity against endobronchial challenge with Mycobacterium bovis","volume":"28","author":"Corner","year":"2010","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.vaccine.2012.02.018_bib0785","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.tvjl.2011.03.007","article-title":"Control of tuberculosis in badgers by vaccination: where next?","volume":"189","author":"Gormley","year":"2011","journal-title":"Vet J"},{"issue":"1","key":"10.1016\/j.vaccine.2012.02.018_bib0790","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jcpa.2010.10.003","article-title":"Mycobacterium bovis infection in the Eurasian badger (Meles meles): the disease, pathogenesis, epidemiology and control","volume":"144","author":"Corner","year":"2011","journal-title":"J Comp Pathol"},{"issue":"38","key":"10.1016\/j.vaccine.2012.02.018_bib0795","doi-asserted-by":"crossref","first-page":"6265","DOI":"10.1016\/j.vaccine.2010.06.120","article-title":"Oral vaccination of badgers (Meles meles) with BCG and protective immunity against endobronchial challenge with Mycobacterium bovis","volume":"28","author":"Corner","year":"2010","journal-title":"Vaccine"},{"issue":"21","key":"10.1016\/j.vaccine.2012.02.018_bib0800","doi-asserted-by":"crossref","first-page":"3782","DOI":"10.1016\/j.vaccine.2011.03.028","article-title":"Protection of Eurasian badgers (Meles meles) from tuberculosis after intra-muscular vaccination with different doses of BCG","volume":"29","author":"Lesellier","year":"2011","journal-title":"Vaccine"},{"issue":"26","key":"10.1016\/j.vaccine.2012.02.018_bib0805","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1136\/vr.142.26.710","article-title":"Role of infected, non-diseased badgers in the pathogenesis of tuberculosis in the badger","volume":"142","author":"Gallagher","year":"1998","journal-title":"Vet Rec"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0810","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1365-2907.1988.tb00075.x","article-title":"Development of diagnostic tests for, and vaccination against, tuberculosis in badgers","volume":"18","author":"Stuart","year":"1988","journal-title":"Mammal Rev"},{"issue":"36","key":"10.1016\/j.vaccine.2012.02.018_bib0815","doi-asserted-by":"crossref","first-page":"6589","DOI":"10.1016\/j.vaccine.2007.06.056","article-title":"Vaccination of white-tailed deer (Odocoileus virginianus) with Mycobacterium bovis bacillus Calmette Guer\u00edn","volume":"25","author":"Palmer","year":"2007","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.vaccine.2012.02.018_bib0820","doi-asserted-by":"crossref","first-page":"247","DOI":"10.7589\/0090-3558-44.2.247","article-title":"Efficacy of oral and parenteral routes of Mycobacterium bovis bacille Calmette\u2013Guerin vaccination against experimental bovine tuberculosis in white-tailed deer (Odocoileus virginianus): a feasibility study","volume":"44","author":"Nol","year":"2008","journal-title":"J Wildl Dis"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2012.02.018_bib0825","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.vetmic.2011.02.022","article-title":"Recent advances in the management of bovine tuberculosis in free-ranging wildlife","volume":"151","author":"O\u2019Brien","year":"2011","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0830","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.rvsc.2008.09.003","article-title":"Evaluation of baits for oral vaccination of European wild boar piglets","volume":"86","author":"Ballesteros","year":"2009","journal-title":"Res Vet Sci"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0835","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1071\/WR08127","article-title":"Selective piglet feeders improve age-related bait specificity and uptake rate in overabundant Eurasian wild boar populations","volume":"36","author":"Ballesteros","year":"2009","journal-title":"Wildl Res"},{"key":"10.1016\/j.vaccine.2012.02.018_bib0840","doi-asserted-by":"crossref","first-page":"6662","DOI":"10.1016\/j.vaccine.2009.08.095","article-title":"First data on Eurasian wild boar response to oral immunization with BCG and challenge with a Mycobacterium bovis field strain","volume":"27","author":"Ballesteros","year":"2009","journal-title":"Vaccine"},{"issue":"11","key":"10.1016\/j.vaccine.2012.02.018_bib0845","first-page":"1025","article-title":"Partial protection against oral challenge with Mycobacterium bovis in ferrets (Mustela furo) following oral vaccination with BCG","volume":"3","author":"Qureshi","year":"1999","journal-title":"Int J Tuberc Lung Dis"},{"issue":"5","key":"10.1016\/j.vaccine.2012.02.018_bib0850","first-page":"473","article-title":"Systemic but not intra-intestinal vaccination with BCG reduces the severity of tuberculosis infection in ferrets (Mustela furo)","volume":"4","author":"Cross","year":"2000","journal-title":"Int J Tuberc Lung Dis"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2012.02.018_bib0855","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.vetimm.2010.04.013","article-title":"BCG vaccination failed to protect yearling African buffaloes (Syncerus caffer) against experimental intratonsilar challenge with Mycobacterium bovis","volume":"137","author":"de Klerk","year":"2010","journal-title":"Vet Immunol Immunopathol"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X12001831?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X12001831?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T14:53:22Z","timestamp":1593701602000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X12001831"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":170,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S0264410X12001831"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2012.02.018","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}