{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:23:57Z","timestamp":1791224637564,"version":"4.1.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.vaccine.2012.10.101","type":"journal-article","created":{"date-parts":[[2012,11,8]],"date-time":"2012-11-08T07:45:21Z","timestamp":1352360721000},"page":"584-590","source":"Crossref","is-referenced-by-count":65,"title":["Hepatitis B vaccination: A completed schedule enough to control HBV lifelong?"],"prefix":"10.1016","volume":"31","author":[{"given":"David","family":"FitzSimons","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greet","family":"Hendrickx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Vorsters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Van Damme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"July 14 (32)","key":"10.1016\/j.vaccine.2012.10.101_bib0005","doi-asserted-by":"crossref","first-page":"4158","DOI":"10.1016\/j.vaccine.2005.03.017","article-title":"Long-term efficacy of hepatitis B vaccine, booster policy, and impact of hepatitis B virus mutants","volume":"23","author":"FitzSimons","year":"2005","journal-title":"Vaccine"},{"issue":"July 9 (28)","key":"10.1016\/j.vaccine.2012.10.101_bib0010","first-page":"255","article-title":"Hepatitis B vaccines. WHO position paper","volume":"79","author":"World Health Organization","year":"2004","journal-title":"Wkly Epidemiol Rec"},{"issue":"December 23 (RR-16)","key":"10.1016\/j.vaccine.2012.10.101_bib0015","first-page":"1","article-title":"A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) part 1: immunization of infants, children, and adolescents","volume":"54","author":"Mast","year":"2005","journal-title":"MMWR Recomm Rep"},{"key":"10.1016\/j.vaccine.2012.10.101_bib0020","unstructured":"VHPB. Hepatitis B vaccine: long-term efficacy, booster policy, and impact of HBV mutants on hepatitis B vaccination programmes. Viral Hepatitis 2004 20; Available from: www.vhpb.org. [accessed on 03.2.12]."},{"issue":"July 1 (1)","key":"10.1016\/j.vaccine.2012.10.101_bib0025","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1093\/cid\/cir270","article-title":"Hepatitis B and the need for a booster dose","volume":"53","author":"Leuridan","year":"2011","journal-title":"Clin Infect Dis"},{"issue":"October (10)","key":"10.1016\/j.vaccine.2012.10.101_bib0030","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1097\/INF.0b013e31817702ba","article-title":"Persistence of protection against hepatitis B virus infection among adolescents vaccinated with recombinant hepatitis B vaccine beginning at birth: a 15-year follow-up study","volume":"27","author":"Bialek","year":"2008","journal-title":"Pediatr Infect Dis J"},{"issue":"March 17 (12)","key":"10.1016\/j.vaccine.2012.10.101_bib0035","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/j.vaccine.2008.01.028","article-title":"Long-term antibody persistence in children primed and boosted with a DTPw-HBV vaccine at 2, 4, 6, 18, months of age","volume":"26","author":"Poovorawan","year":"2008","journal-title":"Vaccine"},{"issue":"November 1 (9)","key":"10.1016\/j.vaccine.2012.10.101_bib0040","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1086\/606119","article-title":"Antibody levels and protection after hepatitis B vaccine: results of a 22-year follow-up study and response to a booster dose","volume":"200","author":"McMahon","year":"2009","journal-title":"J Infect Dis"},{"issue":"July 1 (1)","key":"10.1016\/j.vaccine.2012.10.101_bib0045","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1086\/599331","article-title":"Long-term benefit of hepatitis B vaccination among children in Thailand with transient hepatitis B virus infection who were born to hepatitis B surface antigen-positive mothers","volume":"200","author":"Poovorawan","year":"2009","journal-title":"J Infect Dis"},{"issue":"January 8 (3)","key":"10.1016\/j.vaccine.2012.10.101_bib0050","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.vaccine.2009.10.074","article-title":"Persistence of antibodies and immune memory to hepatitis B vaccine 20 years after infant vaccination in Thailand","volume":"28","author":"Poovorawan","year":"2010","journal-title":"Vaccine"},{"issue":"November (11)","key":"10.1016\/j.vaccine.2012.10.101_bib0055","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S1473-3099(10)70195-X","article-title":"Hepatitis B immune memory in children primed with hexavalent vaccines and given monovalent booster vaccines: an open-label, randomised, controlled, multicentre study","volume":"10","author":"Zanetti","year":"2010","journal-title":"Lancet Infect Dis"},{"issue":"May (5)","key":"10.1016\/j.vaccine.2012.10.101_bib0060","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1002\/hep.23543","article-title":"Determination of immune memory to hepatitis B vaccination through early booster response in college students","volume":"51","author":"Jan","year":"2010","journal-title":"Hepatology"},{"issue":"October 13 (44)","key":"10.1016\/j.vaccine.2012.10.101_bib0065","doi-asserted-by":"crossref","first-page":"7835","DOI":"10.1016\/j.vaccine.2011.07.098","article-title":"Presence of immune memory and immunity to hepatitis B virus in adults after neonatal hepatitis B vaccination","volume":"29","author":"Zhu","year":"2011","journal-title":"Vaccine"},{"issue":"July (7)","key":"10.1016\/j.vaccine.2012.10.101_bib0070","doi-asserted-by":"crossref","first-page":"896","DOI":"10.4161\/hv.19989","article-title":"Persistence and immune memory to hepatitis B vaccine 20 years after primary vaccination of Thai infants, born to HBsAg and HBeAg positive mothers","volume":"8","author":"Poovorawan","year":"2012","journal-title":"Hum Vaccin Immunother"},{"key":"10.1016\/j.vaccine.2012.10.101_bib0075","unstructured":"CDC-Advisory Committee on Immunization Practices (ACIP). Available from: http:\/\/www.cdc.gov\/vaccines\/recs\/acip\/default.htm. [accessed on 16.7.2012]."},{"issue":"March 18 (17\u201318)","key":"10.1016\/j.vaccine.2012.10.101_bib0080","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1016\/j.vaccine.2005.01.068","article-title":"Dramatic decline in acute hepatitis B infection and disease incidence rates among adolescents and young people after 12 years of a mass hepatitis B vaccination programme of pre-adolescents in the schools of Catalonia (Spain)","volume":"23","author":"Salleras","year":"2005","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2012.10.101_bib0085","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1093\/epirev\/mxj010","article-title":"Nationwide hepatitis B vaccination program in Taiwan: effectiveness in the 20 years after it was launched","volume":"28","author":"Chien","year":"2006","journal-title":"Epidemiol Rev"},{"issue":"October (10)","key":"10.1016\/j.vaccine.2012.10.101_bib0090","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1111\/j.1365-3156.2006.01709.x","article-title":"Hepatitis B seroprevalence in Thailand: 12 years after hepatitis B vaccine integration into the national expanded programme on immunization","volume":"11","author":"Chongsrisawat","year":"2006","journal-title":"Trop Med Int Health"},{"issue":"May (5)","key":"10.1016\/j.vaccine.2012.10.101_bib0095","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1365-2893.2010.01312.x","article-title":"Evidence of protection against clinical and chronic hepatitis B infection 20 years after infant vaccination in a high endemicity region","volume":"18","author":"Poovorawan","year":"2011","journal-title":"J Viral Hepat"},{"key":"10.1016\/j.vaccine.2012.10.101_bib0100","unstructured":"National Notifiable Disease Surveillance Sytem\u2013CDC. Available from: http:\/\/www.cdc.gov\/osels\/ph_surveillance\/nndss\/nndsshis.htm. [accessed on 04.9.2012]."},{"issue":"February (2)","key":"10.1016\/j.vaccine.2012.10.101_bib0105","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jinf.2010.11.014","article-title":"Evaluation of the compliance with the protocol for preventing perinatal hepatitis B infection in Italy","volume":"62","author":"Spada","year":"2011","journal-title":"J Infect"},{"issue":"November (11)","key":"10.1016\/j.vaccine.2012.10.101_bib0110","doi-asserted-by":"crossref","first-page":"3216","DOI":"10.1158\/1055-9965.EPI-08-0303","article-title":"20 years into the Gambia Hepatitis Intervention Study: assessment of initial hypotheses and prospects for evaluation of protective effectiveness against liver cancer","volume":"17","author":"Viviani","year":"2008","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.vaccine.2012.10.101_bib0115","unstructured":"National Institute for Public Health and the Environment. Hepatitis B vaccination program. Available from: http:\/\/www.rivm.nl\/Onderwerpen\/Ziekten_Aandoeningen\/H\/Hepatitis_B\/Hepatitis_B_in_het_Rijksvaccinatieprogramma. [accessed on 04.9.12]."},{"key":"10.1016\/j.vaccine.2012.10.101_bib0120","unstructured":"World Health Organization. Hepatitis B position paper preparation. Grading of scientific evidence (duration). Available from: http:\/\/www.who.int\/immunization\/hepb_grad_duration.pdf. [accessed on 03.02.12]."},{"issue":"October 1 (40)","key":"10.1016\/j.vaccine.2012.10.101_bib0125","first-page":"405","article-title":"Hepatitis B vaccines. WHO Position paper","volume":"84","author":"World Health Organization","year":"2009","journal-title":"Wkly Epidemiol Rec"},{"issue":"January 30 (5)","key":"10.1016\/j.vaccine.2012.10.101_bib0130","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.vaccine.2005.08.058","article-title":"B surface antigen-specific T and B cell memory in individuals who had lost protective antibodies after hepatitis B vaccination","volume":"24","author":"Bauer","year":"2006","journal-title":"Vaccine"},{"issue":"September 4 (3A)","key":"10.1016\/j.vaccine.2012.10.101_bib0135","doi-asserted-by":"crossref","first-page":"36S","DOI":"10.1016\/0002-9343(89)90530-5","article-title":"Factors influencing the immune response to hepatitis B vaccine, booster dose guidelines, and vaccine protocol recommendations","volume":"87","author":"Hollinger","year":"1989","journal-title":"Am J Med"},{"issue":"September (3)","key":"10.1016\/j.vaccine.2012.10.101_bib0140","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1093\/ije\/20.3.764","article-title":"Hepatitis B vaccine in the Gambian Expanded Programme on Immunization: factors influencing antibody response","volume":"20","author":"Inskip","year":"1991","journal-title":"Int J Epidemiol"},{"issue":"April (5)","key":"10.1016\/j.vaccine.2012.10.101_bib0145","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/0264-410X(94)00010-K","article-title":"Quantification of hepatitis B vaccine-induced antibodies as a predictor of anti-HBs persistence","volume":"13","author":"Gesemann","year":"1995","journal-title":"Vaccine"},{"issue":"October 15\u201321 (9494)","key":"10.1016\/j.vaccine.2012.10.101_bib0150","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/S0140-6736(05)67568-X","article-title":"Long-term immunogenicity of hepatitis B vaccination and policy for booster: an Italian multicentre study","volume":"366","author":"Zanetti","year":"2005","journal-title":"Lancet"},{"issue":"October (5)","key":"10.1016\/j.vaccine.2012.10.101_bib0155","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s15010-010-0039-7","article-title":"Long-term protection against hepatitis B after newborn vaccination: 20-year follow-up","volume":"38","author":"Roznovsky","year":"2010","journal-title":"Infection"},{"issue":"June 1 (11)","key":"10.1016\/j.vaccine.2012.10.101_bib0160","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1086\/503433","article-title":"Long-term protection against carriage of hepatitis B virus after infant vaccination","volume":"193","author":"van der Sande","year":"2006","journal-title":"J Infect Dis"},{"issue":"8","key":"10.1016\/j.vaccine.2012.10.101_bib0165","doi-asserted-by":"crossref","first-page":"e12273","DOI":"10.1371\/journal.pone.0012273","article-title":"Host genetic factors and vaccine-induced immunity to HBV infection: haplotype analysis","volume":"5","author":"Ryckman","year":"2010","journal-title":"PLoS ONE"},{"issue":"October 9 (15)","key":"10.1016\/j.vaccine.2012.10.101_bib0170","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1056\/NEJM198010093031501","article-title":"Hepatitis B vaccine: demonstration of efficacy in a controlled clinical trial in a high-risk population in the United States","volume":"303","author":"Szmuness","year":"1980","journal-title":"N Engl J Med"},{"issue":"July 24 (4)","key":"10.1016\/j.vaccine.2012.10.101_bib0175","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1056\/NEJM198607243150401","article-title":"Long-term immunogenicity and efficacy of hepatitis B vaccine in homosexual men","volume":"315","author":"Hadler","year":"1986","journal-title":"N Engl J Med"},{"issue":"September (3)","key":"10.1016\/j.vaccine.2012.10.101_bib0180","doi-asserted-by":"crossref","first-page":"362","DOI":"10.7326\/0003-4819-97-3-362","article-title":"The prevention of hepatitis B with vaccine, Report of the centers for disease control multi-center efficacy trial among homosexual men","volume":"97","author":"Francis","year":"1982","journal-title":"Ann Intern Med"},{"issue":"August (2)","key":"10.1016\/j.vaccine.2012.10.101_bib0185","doi-asserted-by":"crossref","first-page":"e373","DOI":"10.1542\/peds.2007-0131","article-title":"Differences in response to a hepatitis B vaccine booster dose among Alaskan children and adolescents vaccinated during infancy","volume":"120","author":"Samandari","year":"2007","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.vaccine.2012.10.101_bib0190","doi-asserted-by":"crossref","first-page":"e753","DOI":"10.1371\/journal.pone.0000753","article-title":"Long-term protection against HBV chronic carriage of Gambian adolescents vaccinated in infancy and immune response in HBV booster trial in adolescence","volume":"2","author":"van der Sande","year":"2007","journal-title":"PLoS ONE"},{"issue":"May 15 (10)","key":"10.1016\/j.vaccine.2012.10.101_bib0195","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1086\/587695","article-title":"Humoral and cellular immune responses to a hepatitis B vaccine booster 15\u201318 years after neonatal immunization","volume":"197","author":"Lu","year":"2008","journal-title":"J Infect Dis"},{"issue":"April (2)","key":"10.1016\/j.vaccine.2012.10.101_bib0200","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1089\/vim.2008.0087","article-title":"Long-term humoral and cellular immune response to hepatitis B vaccine in high-risk children 18\u201320 years after neonatal immunization","volume":"22","author":"Chinchai","year":"2009","journal-title":"Viral Immunol"},{"key":"10.1016\/j.vaccine.2012.10.101_bib0205","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1471-2334-10-9","article-title":"Lasting immune memory against hepatitis B in children after primary immunization with 4 doses of DTPa-HBV-IPV\/Hib in the first and 2nd year of life","volume":"10","author":"Steiner","year":"2010","journal-title":"BMC Infect Dis"},{"issue":"March 13 (12)","key":"10.1016\/j.vaccine.2012.10.101_bib0210","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1016\/j.vaccine.2009.01.027","article-title":"Long-term efficacy of plasma-derived and recombinant hepatitis B vaccines in a rural township of Central Taiwan","volume":"27","author":"Kao","year":"2009","journal-title":"Vaccine"},{"issue":"3 Pt B","key":"10.1016\/j.vaccine.2012.10.101_bib0215","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3851\/IMP1555","article-title":"Breakthrough HBV infection in vaccinated children in Taiwan: surveillance for HBV mutants","volume":"15","author":"Chang","year":"2010","journal-title":"Antivir Ther"},{"issue":"December (12)","key":"10.1016\/j.vaccine.2012.10.101_bib0220","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1111\/j.1872-034X.2010.00733.x","article-title":"Meta-analysis of the association between anti-HBc seropositivity and a poor prognosis of chronic HCV infection","volume":"40","author":"Nan","year":"2010","journal-title":"Hepatol Res"},{"issue":"1","key":"10.1016\/j.vaccine.2012.10.101_bib0225","article-title":"Editorial","volume":"13","author":"Jilg","year":"2004","journal-title":"Viral Hepat"},{"issue":"March 1 (5)","key":"10.1016\/j.vaccine.2012.10.101_bib0230","doi-asserted-by":"crossref","first-page":"333","DOI":"10.7326\/0003-4819-142-5-200503010-00008","article-title":"Antibody levels and protection after hepatitis B vaccination: results of a 15-year follow-up","volume":"142","author":"McMahon","year":"2005","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.vaccine.2012.10.101_bib0235","unstructured":"Tosti ME. Presentation on VHPB website: Breakthrough HBV infections in vaccinated people: a ten-year surveillance study in Italy. 2011 Available from: http:\/\/www.vhpb.org\/files\/html\/Meetings_and_publications\/Presentations\/MILS53.pdf. [accessed on 04.09.12]."},{"issue":"3 Pt B","key":"10.1016\/j.vaccine.2012.10.101_bib0240","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3851\/IMP1556","article-title":"Potential threat of drug-resistant and vaccine-escape HBV mutants to public health","volume":"15","author":"Teo","year":"2010","journal-title":"Antivir Ther"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X12015745?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X12015745?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,21]],"date-time":"2018-10-21T15:57:04Z","timestamp":1540137424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X12015745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":48,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0264410X12015745"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2012.10.101","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}