{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:07:16Z","timestamp":1792670836141,"version":"4.5.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003762","name":"Institut Pasteur","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003762","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.vaccine.2012.12.022","type":"journal-article","created":{"date-parts":[[2012,12,21]],"date-time":"2012-12-21T13:31:11Z","timestamp":1356096671000},"page":"1113-1116","source":"Crossref","is-referenced-by-count":98,"title":["Could the multicomponent meningococcal serogroup B vaccine (4CMenB) control Neisseria meningitidis capsular group X outbreaks in Africa?"],"prefix":"10.1016","volume":"31","author":[{"given":"Eva","family":"Hong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marzia Monica","family":"Giuliani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ala-Eddine","family":"Deghmane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Comanducci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brunella","family":"Brunelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Dull","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariagrazia","family":"Pizza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhamed-Kheir","family":"Taha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl.","key":"10.1016\/j.vaccine.2012.12.022_bib0005","first-page":"1","article-title":"Cerebrospinal Meningitis in Africa","volume":"28","author":"Lapeyssonnie","year":"1963","journal-title":"Bull World Health Organ"},{"issue":"4","key":"10.1016\/j.vaccine.2012.12.022_bib0010","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1517\/14656566.5.4.855","article-title":"Meningococcal conjugate vaccines","volume":"5","author":"Zimmer","year":"2004","journal-title":"Expert Opin Pharmacother"},{"issue":"5","key":"10.1016\/j.vaccine.2012.12.022_bib0015","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1086\/511646","article-title":"Meningococcal meningitis: unprecedented incidence of serogroup X-related cases in 2006 in Niger","volume":"44","author":"Boisier","year":"2007","journal-title":"Clin Infect Dis"},{"issue":"3","key":"10.1016\/j.vaccine.2012.12.022_bib0020","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1128\/JCM.40.3.1083-1084.2002","article-title":"Neisseria meningitidis serogroups W135 and A were equally prevalent among meningitis cases occurring at the end of the 2001 epidemics in Burkina Faso and Niger","volume":"40","author":"Taha","year":"2002","journal-title":"J Clin Microbiol"},{"issue":"12","key":"10.1016\/j.vaccine.2012.12.022_bib0025","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1046\/j.1360-2276.2003.01126.x","article-title":"Outbreaks of serogroup X meningococcal meningitis in Niger 1995\u20132000","volume":"8","author":"Djibo","year":"2003","journal-title":"Trop Med Int Health"},{"issue":"7","key":"10.1016\/j.vaccine.2012.12.022_bib0030","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1086\/507339","article-title":"The rise and fall of epidemic Neisseria meningitidis serogroup W135 meningitis in Burkina Faso: 2002\u20132005","volume":"43","author":"Traore","year":"2006","journal-title":"Clin Infect Dis"},{"issue":"5","key":"10.1016\/j.vaccine.2012.12.022_bib0035","doi-asserted-by":"crossref","first-page":"462","DOI":"10.3201\/eid0805.010227","article-title":"Clonal groupings in serogroup X Neisseria meningitidis","volume":"8","author":"Gagneux","year":"2002","journal-title":"Emerg Infect Dis"},{"issue":"5","key":"10.1016\/j.vaccine.2012.12.022_bib0040","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1086\/339010","article-title":"Prospective study of a serogroup X Neisseria meningitidis outbreak in northern Ghana","volume":"185","author":"Gagneux","year":"2002","journal-title":"J Infect Dis"},{"issue":"Suppl. 1","key":"10.1016\/j.vaccine.2012.12.022_bib0045","doi-asserted-by":"crossref","first-page":"A18","DOI":"10.1016\/j.vaccine.2007.04.035","article-title":"Genetic diversification of Neisseria meningitidis during waves of colonization and disease in the meningitis belt of sub-Saharan Africa","volume":"25","author":"Leimkugel","year":"2007","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.vaccine.2012.12.022_bib0050","doi-asserted-by":"crossref","first-page":"e101","DOI":"10.1371\/journal.pmed.0040101","article-title":"Clonal waves of Neisseria colonisation and disease in the African meningitis belt: eight- year longitudinal study in northern Ghana","volume":"4","author":"Leimkugel","year":"2007","journal-title":"PLoS Med"},{"issue":"24","key":"10.1016\/j.vaccine.2012.12.022_bib0055","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1056\/NEJMoa1003812","article-title":"Immunogenicity and safety of a meningococcal A conjugate vaccine in Africans","volume":"364","author":"Sow","year":"2011","journal-title":"N Engl J Med"},{"issue":"6516","key":"10.1016\/j.vaccine.2012.12.022_bib0060","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/373715a0","article-title":"Molecular characterization of eukaryotic polysialyltransferase-1","volume":"373","author":"Eckhardt","year":"1995","journal-title":"Nature"},{"issue":"17","key":"10.1016\/j.vaccine.2012.12.022_bib0065","doi-asserted-by":"crossref","first-page":"15349","DOI":"10.1074\/jbc.M208837200","article-title":"Functional relationships of the sialyltransferases involved in expression of the polysialic acid capsules of Escherichia coli K1 and K92 and Neisseria meningitidis groups B or C","volume":"278","author":"Steenbergen","year":"2003","journal-title":"J Biol Chem"},{"issue":"29","key":"10.1016\/j.vaccine.2012.12.022_bib0070","doi-asserted-by":"crossref","first-page":"10834","DOI":"10.1073\/pnas.0603940103","article-title":"A universal vaccine for serogroup B meningococcus","volume":"103","author":"Giuliani","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"issue":"45","key":"10.1016\/j.vaccine.2012.12.022_bib0075","doi-asserted-by":"crossref","first-page":"19490","DOI":"10.1073\/pnas.1013758107","article-title":"Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines","volume":"107","author":"Donnelly","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"10.1016\/j.vaccine.2012.12.022_bib0080","doi-asserted-by":"crossref","first-page":"e19513","DOI":"10.1371\/journal.pone.0019513","article-title":"Emergence of Epidemic Neisseria meningitidis serogroup X Meningitis in Togo and Burkina Faso","volume":"6","author":"Delrieu","year":"2011","journal-title":"PLoS ONE"},{"issue":"9","key":"10.1016\/j.vaccine.2012.12.022_bib0085","doi-asserted-by":"crossref","first-page":"e1302","DOI":"10.1371\/journal.pntd.0001302","article-title":"Meningococcal factor H binding proteins in epidemic strains from Africa: implications for vaccine development","volume":"5","author":"Pajon","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"issue":"1","key":"10.1016\/j.vaccine.2012.12.022_bib0090","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0882-4010(88)90045-9","article-title":"Neisseria meningitidis group B serosubtyping using monoclonal antibodies in whole-cell ELISA","volume":"4","author":"Abdillahi","year":"1988","journal-title":"Microb Pathog"},{"issue":"Pt 8","key":"10.1016\/j.vaccine.2012.12.022_bib0095","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1099\/mic.0.050518-0","article-title":"Molecular typing methods for outbreak detection and surveillance of invasive disease caused by Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae, a review","volume":"157","author":"Harrison","year":"2011","journal-title":"Microbiology"},{"issue":"11","key":"10.1016\/j.vaccine.2012.12.022_bib0100","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1084\/jem.20020407","article-title":"NadA: a novel vaccine candidate of Neisseria meningitidis","volume":"195","author":"Comanducci","year":"2002","journal-title":"J Exp Med"},{"issue":"6","key":"10.1016\/j.vaccine.2012.12.022_bib0105","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1084\/jem.20021911","article-title":"Vaccination against Neisseria meningitidis using three variants of the lipoprotein GNA1870","volume":"197","author":"Masignani","year":"2003","journal-title":"J Exp Med"},{"issue":"10","key":"10.1016\/j.vaccine.2012.12.022_bib0110","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1128\/CVI.00202-12","article-title":"Interlaboratory standardization of the sandwich enzyme-linked immunosorbent assay designed for MATS: a rapid, reproducible method for estimating the strain coverage of investigational vaccines","volume":"19","author":"Plikaytis","year":"2012","journal-title":"Clin Vaccine Immunol"},{"issue":"3","key":"10.1016\/j.vaccine.2012.12.022_bib0115","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1128\/CDLI.8.3.616-623.2001","article-title":"Importance of complement source in measuring meningococcal bactericidal titers","volume":"8","author":"Santos","year":"2001","journal-title":"Clin Diagn Lab Immunol"},{"issue":"Suppl. 2","key":"10.1016\/j.vaccine.2012.12.022_bib0120","doi-asserted-by":"crossref","first-page":"B112","DOI":"10.1016\/j.vaccine.2009.04.065","article-title":"Bactericidal antibody is the immunologic surrogate of protection against meningococcal disease","volume":"27","author":"Frasch","year":"2009","journal-title":"Vaccine"},{"issue":"15","key":"10.1016\/j.vaccine.2012.12.022_bib0125","doi-asserted-by":"crossref","first-page":"4797","DOI":"10.1016\/S0021-9258(19)42390-9","article-title":"Studies on the group-specific polysaccharide of Neisseria meningitidis serogroup X and an improved procedure for its isolation","volume":"249","author":"Bundle","year":"1974","journal-title":"J Biol Chem"},{"issue":"40","key":"10.1016\/j.vaccine.2012.12.022_bib0130","doi-asserted-by":"crossref","first-page":"5812","DOI":"10.1016\/j.vaccine.2012.07.032","article-title":"Characterization of size: structure and purity of serogroup X Neisseria meningitidis polysaccharide, and development of an assay for quantification of human antibodies","volume":"30","author":"Xie","year":"2012","journal-title":"Vaccine"},{"issue":"16","key":"10.1016\/j.vaccine.2012.12.022_bib0135","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1001\/jama.281.16.1520","article-title":"Immunogenicity of 2 serogroup B outer-membrane protein meningococcal vaccines: a randomized controlled trial in Chile","volume":"281","author":"Tappero","year":"1999","journal-title":"J Am Med Assoc"},{"issue":"6","key":"10.1016\/j.vaccine.2012.12.022_bib0140","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/S1473-3099(11)70027-5","article-title":"From tailor-made to ready-to-wear meningococcal B vaccines: longitudinal study of a clonal meningococcal B outbreak","volume":"11","author":"Caron","year":"2011","journal-title":"Lancet Infect Dis"}],"updated-by":[{"DOI":"10.1016\/j.vaccine.2020.06.048","type":"expression_of_concern","label":"Expression of concern","source":"retraction-watch","updated":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T00:00:00Z","timestamp":1593648000000},"record-id":"23683"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X12017926?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X12017926?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T10:05:30Z","timestamp":1643969130000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X12017926"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":28,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S0264410X12017926"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2012.12.022","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]}}}