{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T22:08:24Z","timestamp":1759010904921},"reference-count":54,"publisher":"Elsevier BV","issue":"40","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Department of Science and Technology\/Department of Science and Technology\/National Research Foundation: Vaccine Preventable Diseases and the Medical Research Council: Respiratory and Meningeal Pathogens Research Unit, University of the Witwatersrand, Johannesburg, South Africa"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.vaccine.2013.06.097","type":"journal-article","created":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T15:21:32Z","timestamp":1373296892000},"page":"4421-4427","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Association of Streptococcus pneumoniae common protein antigen (CPA) antibodies and pneumococcal nasopharyngeal colonization in HIV-infected and HIV-uninfected African children"],"prefix":"10.1016","volume":"31","author":[{"given":"Z.","family":"Ditse","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.V.","family":"Adrian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Kuwanda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.A.","family":"Madhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2013.06.097_bib0005","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/00006454-200003000-00003","article-title":"Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. Northern California Kaiser Permanente Vaccine Study Center Group","volume":"19","author":"Black","year":"2000","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0010","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1056\/NEJM200102083440602","article-title":"Efficacy of a pneumococcal conjugate vaccine against acute otitis media","volume":"344","author":"Eskola","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0015","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/00006454-200301000-00006","article-title":"Impact of the pneumococcal conjugate vaccine on otitis media","volume":"22","author":"Fireman","year":"2003","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0020","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/S0140-6736(00)04222-7","article-title":"Geographical differences in invasive pneumococcal disease rates and serotype frequency in young children","volume":"357","author":"Hausdorff","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0025","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1097\/00006454-200203000-00003","article-title":"Efficacy, immunogenicity and safety of heptavalent pneumococcal conjugate vaccine in low birth weight and preterm infants","volume":"21","author":"Shinefield","year":"2002","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0030","series-title":"Pneumococcal vaccines: the impact of conjugate vaccines","author":"Siber","year":"2008"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0035","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1016\/S0140-6736(10)62225-8","article-title":"Serotype replacement in disease after pneumococcal vaccination","volume":"378","author":"Weinberger","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0040","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1016\/j.vaccine.2003.11.038","article-title":"Pneumococcal vaccines: an update on current strategies","volume":"22","author":"Bogaert","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0045","doi-asserted-by":"crossref","first-page":"3293","DOI":"10.1128\/IAI.58.10.3293-3299.1990","article-title":"Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae","volume":"58","author":"Crain","year":"1990","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0050","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1084\/jem.165.2.381","article-title":"Use of insertional inactivation to facilitate studies of biological properties of pneumococcal surface protein A (PspA)","volume":"165","author":"McDaniel","year":"1987","journal-title":"J Exp Med"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0055","doi-asserted-by":"crossref","first-page":"6533","DOI":"10.1128\/IAI.67.12.6533-6542.1999","article-title":"The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia","volume":"67","author":"Brooks-Walter","year":"1999","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0060","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1046\/j.1365-2958.1997.5111879.x","article-title":"Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases","volume":"25","author":"Dintilhac","year":"1997","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0065","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1128\/IAI.62.1.319-324.1994","article-title":"Cloning and nucleotide sequence analysis of PsaA, the Streptococcus pneumoniae gene encoding a 37-kilodalton protein homologous to previously reported Streptococcus sp adhesins","volume":"62","author":"Sampson","year":"1994","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0070","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1128\/IAI.41.3.1212-1216.1983","article-title":"Inhibition of human polymorphonuclear leukocyte respiratory burst, bactericidal activity, and migration by pneumolysin","volume":"41","author":"Paton","year":"1983","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0075","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1128\/IAI.00378-10","article-title":"Preclinical evaluation of the Pht proteins as potential cross-protective pneumococcal vaccine antigens","volume":"79","author":"Godfroid","year":"2011","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0080","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1016\/j.vaccine.2006.09.026","article-title":"Development of lactococcal GEM-based pneumococcal vaccines","volume":"25","author":"Audouy","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0085","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1084\/jem.20071168","article-title":"Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies","volume":"205","author":"Giefing","year":"2008","journal-title":"J Exp Med"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0090","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.vaccine.2005.07.055","article-title":"Development of natural antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A and pneumolysin in Filipino pregnant women and their infants in relation to pneumococcal carriage","volume":"24","author":"Holmlund","year":"2006","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0095","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1128\/IAI.01379-10","article-title":"Natural antibodies against several pneumococcal virulence proteins in children during the pre-pneumococcal-vaccine era: the generation R study","volume":"79","author":"Lebon","year":"2011","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0100","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1128\/IAI.00037-12","article-title":"Nasopharyngeal colonization elicits antibody responses to staphylococcal and pneumococcal proteins that are not associated with a reduced risk of subsequent carriage","volume":"80","author":"Prevaes","year":"2012","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0105","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1086\/315822","article-title":"Natural development of antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A, and pneumolysin in relation to pneumococcal carriage and Acute Otitis Media","volume":"182","author":"Rapola","year":"2000","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0110","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1016\/j.vaccine.2004.01.042","article-title":"Development of antibodies against pneumococcal proteins \u03b1-enolase, immunoglobulin A1 protease, streptococcal lipoprotein rotamase A, and putative proteinase maturation protein A in relation to pneumococcal carriage and Otitis Media","volume":"22","author":"Adrian","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0115","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1574-695X.2005.00012.x","article-title":"Development of antibodies against the putative proteinase maturation protein A in relation to pneumococcal carriage and otitis media","volume":"46","author":"Bogaert","year":"2006","journal-title":"FEMS Immunol Med Microbiol"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0120","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1074\/jbc.M510014200","article-title":"The Streptococcal lipoprotein rotamase A is a functional peptidyl\u2013prolyl isomerase involved in pneumococcal colonization","volume":"281","author":"Hermans","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0125","doi-asserted-by":"crossref","first-page":"4215","DOI":"10.1073\/pnas.0637469100","article-title":"Antibody-enhanced pneumococcal adherence requires IgA1 protease","volume":"100","author":"Weiser","year":"2003","journal-title":"PNAS"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0130","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/00006454-200002000-00011","article-title":"Human antibodies to pneumococcal surface protein A in health and disease","volume":"19","author":"Virolanein","year":"2000","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0135","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/01.inf.0000048676.93549.d1","article-title":"Report from a WHO working group: standard method for detecting upper respiratory carriage of Streptococcus pneumoniae","volume":"22","author":"O\u2019Brien","year":"2003","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0140","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1056\/NEJMoa035060","article-title":"A trial of a 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection","volume":"349","author":"Klugman","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0145","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1016\/j.vaccine.2006.09.019","article-title":"Long-term immunogenicity and efficacy of a 9-valent conjugate pneumococcal vaccine in human immunodeficient virus infected and non-infected children in the absence of a booster dose of vaccine","volume":"25","author":"Madhi","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0150","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1086\/522164","article-title":"Long-term effect of pneumococcal conjugate vaccine on nasopharyngeal colonization by Streptococcus pneumoniae and associated interactions with Staphylococcus aureus and Haemophilus influenzae colonization in HIV-infected and HIV-uninfected children","volume":"196","author":"Madhi","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0155","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1086\/653704","article-title":"Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants","volume":"202","author":"Madhi","year":"2010","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0160","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0003-2697(90)90267-D","article-title":"Zero-length crosslinking procedure with the use of active esters","volume":"185","author":"Grabarek","year":"1990","journal-title":"Anal Biochem"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0165","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jim.2004.11.006","article-title":"Development and validation of a nonaplex assay for the simultaneous quantitation of antibodies to nine Streptococcus pneumoniae serotypes","volume":"296","author":"Lal","year":"2005","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0170","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1309\/LMCH-C4Q2-VFL9-3T1A","article-title":"A multiplexed fluorescent microsphere immunoassay for antibodies to pneumococcal capsular polysaccharides","volume":"117","author":"Pickering","year":"2002","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0175","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1164\/ajrccm.152.6.8520768","article-title":"Impaired natural immunity to pneumolysin during human immunodeficiency virus infection in the United States and Africa","volume":"152","author":"Amdahl","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0180","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1016\/j.vaccine.2009.04.026","article-title":"Effect of recurrent invasive pneumococcal disease on serum anti-pneumolysin IgG titers in HIV infected adults","volume":"27","author":"Etuwewe","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0185","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1164\/ajrccm.163.3.2002066","article-title":"Anti-pneumolysin antibody titers in HIV sero-positive injection drug users before and after pneumococcal bacteremia","volume":"163","author":"Sullivan","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0190","doi-asserted-by":"crossref","first-page":"5724","DOI":"10.1128\/IAI.71.10.5724-5732.2003","article-title":"Serum immunoglobulin G response to candidate vaccine antigens during experimental human pneumococcal colonization","volume":"71","author":"McCool","year":"2003","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0195","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1086\/315009","article-title":"Immunogenicity and impact on nasopharyngeal carriage of a nonavent pneumococcal conjugate vaccine","volume":"180","author":"Mbelle","year":"1999","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0200","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1586\/14760584.7.6.725","article-title":"6th international symposium on pneumococci and pneumococcal diseases","volume":"7","author":"Ulloa-Gutierrez","year":"2008","journal-title":"Expert Rev Vaccines"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0205","doi-asserted-by":"crossref","first-page":"e30787","DOI":"10.1371\/journal.pone.0030787","article-title":"The prevalence and risk factors for pneumococcal colonization of the nasopharynx among children in Kilifi District, Kenya","volume":"7","author":"Abdullahi","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0210","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1086\/528806","article-title":"Impact of human immunodeficiency virus infection on Streptococcus pneumoniae colonization and seroepidemiology among Zambian Women","volume":"197","author":"Gill","year":"2008","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0215","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1038\/nsb724","article-title":"A novel solenoid fold in the cell wall anchoring domain of the pneumococcal virulence factor LytA","volume":"8","author":"Fernandez-Tornero","year":"2001","journal-title":"Nat Struct Biol"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0220","doi-asserted-by":"crossref","first-page":"e27929","DOI":"10.1371\/journal.pone.0027929","article-title":"Persistent high burden of invasive pneumococcal disease in South African HIV-infected adults in the Era of an antiretroviral treatment program","volume":"6","author":"Nunes","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0225","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1086\/420933","article-title":"Invasive pneumococcal disease in patients infected with HIV: still a threat in the era of highly active antiretroviral therapy","volume":"38","author":"Jordano","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0230","doi-asserted-by":"crossref","first-page":"e25610","DOI":"10.1371\/journal.pone.0025610","article-title":"Impaired CD4 T cell emory response to Streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults","volume":"6","author":"Glennie","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0235","doi-asserted-by":"crossref","first-page":"929","DOI":"10.2471\/BLT.07.049668","article-title":"Effect of presumptive co-trimoxazole prophylaxis on pneumococcal colonization rates, seroepidemiology and antibiotic resistance in Zambian infants: a longitudinal cohort study","volume":"86","author":"Gill","year":"2008","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0240","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.1128\/IAI.70.5.2526-2534.2002","article-title":"Role of pneumococcal surface protein C in nasopharyngeal carriage and pneumoniae and its ability to elicit protection against carriage of Streptococcus pneumoniae","volume":"70","author":"Balachandran","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0245","doi-asserted-by":"crossref","first-page":"5731","DOI":"10.1016\/j.vaccine.2011.05.095","article-title":"Intranasal immunization with recombinant PspA fused with a flagellin enhances cross-protective immunity against Streptococcus pneumoniae infection in mice","volume":"29","author":"Nguyen","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0250","doi-asserted-by":"crossref","first-page":"3028","DOI":"10.1128\/IAI.68.5.3028-3033.2000","article-title":"Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae","volume":"68","author":"Ogunniyi","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0255","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1128\/IAI.01103-06","article-title":"Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae","volume":"75","author":"Ogunniyi","year":"2007","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0260","doi-asserted-by":"crossref","first-page":"5997","DOI":"10.1128\/IAI.69.10.5997-6003.2001","article-title":"Protection against Streptococcus pneumoniae elicited by immunization with pneumolysin and CbpA","volume":"69","author":"Ogunniyi","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0265","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1128\/IAI.69.3.1593-1598.2001","article-title":"Use of a whole genome approach to identify vaccine molecules affording protection against Streptococcus pneumoniae infection","volume":"69","author":"Wizemann","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2013.06.097_bib0270","doi-asserted-by":"crossref","first-page":"4996","DOI":"10.1016\/j.vaccine.2007.04.069","article-title":"Enhanced protection against pneumococcal infection elicited by immunization with the combination of PspA, PspC, and ClpP","volume":"25","author":"Cao","year":"2007","journal-title":"Vaccine"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X13009079?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X13009079?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T02:01:53Z","timestamp":1596074513000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X13009079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":54,"journal-issue":{"issue":"40","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S0264410X13009079"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2013.06.097","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of Streptococcus pneumoniae common protein antigen (CPA) antibodies and pneumococcal nasopharyngeal colonization in HIV-infected and HIV-uninfected African children","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2013.06.097","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}