{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:05:14Z","timestamp":1791266714572,"version":"4.1.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"49","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001826","name":"The Netherlands Organization for Health Research and Development","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Netherlands Organization for Scientific Research"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.vaccine.2014.09.061","type":"journal-article","created":{"date-parts":[[2014,10,16]],"date-time":"2014-10-16T03:30:16Z","timestamp":1413430216000},"page":"6622-6630","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Adverse events and association with age, sex and immunological parameters of Q fever vaccination in patients at risk for chronic Q fever in the Netherlands 2011"],"prefix":"10.1016","volume":"32","author":[{"given":"Teske","family":"Schoffelen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans C.","family":"R\u00fcmke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihai G.","family":"Netea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aura","family":"Timen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"van Deuren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia E.","family":"Vermeer-de Bondt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2014.09.061_bib0005","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1111\/j.1749-6632.1952.tb22660.x","article-title":"Treatment of Q fever with antibiotics","volume":"55","author":"Clark","year":"1952","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0010","doi-asserted-by":"crossref","first-page":"3644","DOI":"10.1128\/AAC.45.12.3644-3646.2001","article-title":"Newer macrolides as empiric treatment for acute Q fever infection","volume":"45","author":"Gikas","year":"2001","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0015","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0140-6736(06)68266-4","article-title":"Q fever","volume":"367","author":"Parker","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0020","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S1473-3099(10)70135-3","article-title":"Long-term outcome of Q fever endocarditis: a 26-year personal survey","volume":"10","author":"Million","year":"2010","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0025","first-page":"1998","article-title":"An outbreak of Q fever in The Netherlands--possible link to goats","volume":"151","author":"Van Steenbergen","year":"2007","journal-title":"Ned Tijdschr Geneeskd"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0030","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1017\/S0950268808001908","article-title":"Investigation of a Q fever outbreak in a rural area of The Netherlands","volume":"137","author":"Karagiannis","year":"2009","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0035","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/978-94-007-4315-1_17","article-title":"Epidemic Q fever in humans in the Netherlands","volume":"984","author":"van der Hoek","year":"2012","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S0950268810002268","article-title":"The Q fever epidemic in The Netherlands: history, onset, response and reflection","volume":"139","author":"Roest","year":"2011","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0045","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1017\/S0950268812001203","article-title":"Screening for Coxiella burnetii seroprevalence in chronic Q fever high-risk groups reveals the magnitude of the Dutch Q fever outbreak","volume":"141","author":"Kampschreur","year":"2012","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0050","doi-asserted-by":"crossref","first-page":"20059","DOI":"10.2807\/ese.17.03.20059-en","article-title":"Shifting priorities in the aftermath of a Q fever epidemic in 2007 to 2009 in The Netherlands: from acute to chronic infection","volume":"17","author":"van der Hoek","year":"2012","journal-title":"Euro Surveill"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0055","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1128\/JCM.03221-13","article-title":"Chronic Q fever in the Netherlands five years after the start of the Q fever epidemic: results from the Dutch Chronic Q Fever Database","volume":"52","author":"Kampschreur","year":"2014","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0060","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/00005792-200003000-00005","article-title":"Q fever 1985\u20131998. Clinical and epidemiologic features of 1,383 infections","volume":"79","author":"Raoult","year":"2000","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0065","doi-asserted-by":"crossref","first-page":"563","DOI":"10.3201\/eid1804.111478","article-title":"Identification of risk factors for chronic Q fever, the Netherlands","volume":"18","author":"Kampschreur","year":"2012","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0070","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1093\/cid\/cit419","article-title":"Evolution from acute Q fever to endocarditis is associated with underlying valvulopathy and age and can be prevented by prolonged antibiotic treatment","volume":"57","author":"Million","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0075","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S1473-3099(11)70016-0","article-title":"Prevention of Q fever endocarditis","volume":"11","author":"Limonard","year":"2011","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0080","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1016\/j.vaccine.2009.02.007","article-title":"Australia's national Q fever vaccination program","volume":"27","author":"Gidding","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0085","series-title":"Human Vaccination Against Q Fever. Publication no 2010\/08","year":"2010"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0090","doi-asserted-by":"crossref","first-page":"2617","DOI":"10.1016\/j.vaccine.2013.03.062","article-title":"Implementation of a Q fever vaccination program for high-risk patients in the Netherlands","volume":"31","author":"Isken","year":"2013","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0095","series-title":"Q fever vaccine and Q-VAX skin test. Product Information \u2013 TGA approved","author":"Q-VAX","year":"2008"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0100","series-title":"A guide to Q fever and Q fever vaccination. Booklet","author":"Marmion","year":"2009"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0105","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1093\/cid\/cit129","article-title":"Specific interferon \u03b3 detection for the diagnosis of previous Q fever","volume":"56","author":"Schoffelen","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0110","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.jinf.2013.08.008","article-title":"Limited humoral and cellular responses to Q fever vaccination in older adults with risk factors for chronic Q fever","volume":"67","author":"Schoffelen","year":"2013","journal-title":"J Infect"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0115","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"370","author":"von Elm","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0120","series-title":"Clinical safety data management: definitions and standards for expedited reporting","author":"European Medicines Agency (EMA)","year":"2006"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0125","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.vaccine.2003.09.007","article-title":"Fever as an adverse event following immunization: case definition and guidelines of data collection, analysis, and presentation","volume":"22","author":"Michael Marcy","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0130","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.vaccine.2003.09.005","article-title":"Nodule at injection site as an adverse event following immunization: case definition and guidelines for data collection, analysis, and presentation","volume":"22","author":"Rothstein","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0135","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1016\/j.vaccine.2008.11.036","article-title":"Guidelines for collection, analysis and presentation of vaccine safety data in pre- and post-licensure clinical studies","volume":"27","author":"Bonhoeffer","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0140","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1177\/003335490912400320","article-title":"OpenEpi: a web-based epidemiologic and statistical calculator for public health","volume":"124","author":"Sullivan","year":"2009","journal-title":"Public Health Rep"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0145","series-title":"R: a language and environment for statistical computing","author":"R Development Core Team","year":"2011"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0150","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1017\/S0950268800059458","article-title":"Vaccine prophylaxis of abattoir-associated Q fever: eight years\u2019 experience in Australian abattoirs","volume":"104","author":"Marmion","year":"1990","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0155","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1001\/archinte.162.6.701","article-title":"Q fever during pregnancy: diagnosis, treatment, and follow-up","volume":"162","author":"Raoult","year":"2002","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0160","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1086\/520661","article-title":"Managing Q fever during pregnancy: the benefits of long-term cotrimoxazole therapy","volume":"45","author":"Carcopino","year":"2007","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0165","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1186\/1471-2334-12-359","article-title":"Maternofetal consequences of Coxiella burnetii infection in pregnancy: a case series of two outbreaks","volume":"12","author":"Boden","year":"2012","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0170","doi-asserted-by":"crossref","first-page":"87","DOI":"10.2105\/AJPH.52.1.87","article-title":"Intradermal sensitivity testing in man with a purified vaccine for Q fever","volume":"52","author":"Lackman","year":"1962","journal-title":"Am J Public Health Nations Health"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0175","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/j.1467-842X.2005.tb00749.x","article-title":"Control strategies for Q fever based on results of pre-vaccination screening in Victoria, 1988 to 2001","volume":"29","author":"Greig","year":"2005","journal-title":"Aust N Z J Public Health"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0180","first-page":"1","article-title":"Q fever vaccination of human volunteers. I. The serologic and skin test response following subcutaneous injections","volume":"78","author":"Luoto","year":"1963","journal-title":"Am J Hyg"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0185","doi-asserted-by":"crossref","first-page":"441","DOI":"10.4161\/hv.8476","article-title":"Sex differences in injection site reactions with human vaccines","volume":"5","author":"Cook","year":"2009","journal-title":"Hum Vaccine"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0190","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.tmaid.2014.01.008","article-title":"Childhood vaccination associated adverse events by sex: a literature review","volume":"12","author":"Weber","year":"2014","journal-title":"Travel Med Infect Dis"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0195","doi-asserted-by":"crossref","first-page":"3548","DOI":"10.1016\/j.vaccine.2014.04.025","volume":"32","author":"Pondo","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0200","article-title":"Adverse events in the Netherlands Vaccination Programme; reports in 2010 and review 1994\u20132010. 205051004","author":"Vermeer-de Bondt","year":"2011","journal-title":"Bilthoven"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0205","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1086\/313896","article-title":"Fever in the elderly","volume":"31","author":"Norman","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0210","doi-asserted-by":"crossref","first-page":"704","DOI":"10.5694\/j.1326-5377.1994.tb125909.x","article-title":"Vaccine prophylaxis of Q fever. A follow-up study of the efficacy of Q-Vax (CSL) 1985-1990","volume":"160","author":"Ackland","year":"1994","journal-title":"Med J Aust"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0215","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1093\/infdis\/157.4.781","article-title":"Markers of cell-mediated immunity after vaccination with an inactivated, whole-cell Q fever vaccine","volume":"157","author":"Izzo","year":"1988","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0220","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1071\/NB07057","article-title":"A review of the efficacy of human Q fever vaccine registered in Australia","volume":"18","author":"Chiu","year":"2007","journal-title":"N S W Public Health Bull"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0225","series-title":"A Q fever vaccine: efficacy and present status","author":"Benenson","year":"1959"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0230","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/j.1440-0960.2005.00158.x","article-title":"Rare complication of Q fever vaccination","volume":"46","author":"Fairweather","year":"2005","journal-title":"Australas J Dermatol"},{"key":"10.1016\/j.vaccine.2014.09.061_bib0235","doi-asserted-by":"crossref","first-page":"166","DOI":"10.5694\/j.1326-5377.2003.tb05479.x","article-title":"A rare local granulomatous complication of Q fever vaccination","volume":"179","author":"Mills","year":"2003","journal-title":"Med J Aust"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X14013395?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X14013395?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T01:01:47Z","timestamp":1650416507000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X14013395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":47,"journal-issue":{"issue":"49","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S0264410X14013395"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2014.09.061","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adverse events and association with age, sex and immunological parameters of Q fever vaccination in patients at risk for chronic Q fever in the Netherlands 2011","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2014.09.061","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}