{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T15:16:01Z","timestamp":1778426161654,"version":"3.51.4"},"reference-count":43,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.vaccine.2015.12.040","type":"journal-article","created":{"date-parts":[[2015,12,24]],"date-time":"2015-12-24T10:52:14Z","timestamp":1450954334000},"page":"616-621","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Cost-utility analysis of dengue vaccination in a country with heterogeneous risk of dengue transmission"],"prefix":"10.1016","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8911-663X","authenticated-orcid":false,"given":"Pablo Wenceslao","family":"Orellano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julieta Itati","family":"Reynoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Christian","family":"Stahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar Daniel","family":"Salomon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.vaccine.2015.12.040_bib0220","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1186\/1471-2458-14-781","article-title":"Climate change and the emergence of vector-borne diseases in Europe: case study of dengue fever","volume":"14","author":"Bouzid","year":"2014","journal-title":"BMC Public Health"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0225","unstructured":"World Health Organization. Dengue and severe dengue fact sheet N\u00b0117. Available at. http:\/\/www.who.int\/mediacentre\/factsheets\/fs117\/en\/Updated May 2015."},{"issue":"1","key":"10.1016\/j.vaccine.2015.12.040_bib0230","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1590\/S0074-02762008005000003","article-title":"Aedes aegypti Aedes albopictus, and dengue in Argentina: current knowledge and future directions","volume":"103","author":"Vezzani","year":"2008","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"2","key":"10.1016\/j.vaccine.2015.12.040_bib0235","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1590\/S0034-89102011000200023","article-title":"Neglected lessons from the 2009 dengue epidemic in Argentina","volume":"45","author":"Zambrini","year":"2011","journal-title":"Rev Saude Publica"},{"issue":"1","key":"10.1016\/j.vaccine.2015.12.040_bib0240","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/2051013613507862","article-title":"Latest developments and future directions in dengue vaccines","volume":"2","author":"Thisyakorn","year":"2014","journal-title":"Ther Adv Vaccines"},{"issue":"12","key":"10.1016\/j.vaccine.2015.12.040_bib0245","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/j.vaccine.2014.01.040","article-title":"A review of successful flavivirus vaccines and the problems with those flaviviruses for which vaccines are not yet available","volume":"32","author":"Ishikawa","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0250","doi-asserted-by":"crossref","DOI":"10.1016\/S0140-6736(14)61060-6","article-title":"Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial","author":"Capeding","year":"2014","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.vaccine.2015.12.040_bib0255","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1056\/NEJMoa1411037","article-title":"Efficacy of a tetravalent dengue vaccine in children in Latin America","volume":"372","author":"Villar","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0260","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMoa1506223","article-title":"Efficacy and long-term safety of a dengue vaccine in regions of endemic disease","author":"Hadinegoro","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0265","doi-asserted-by":"crossref","DOI":"10.1016\/S0140-6736(14)61142-9","article-title":"Dengue vaccines: dawning at last?","author":"Wilder-Smith","year":"2014","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.vaccine.2015.12.040_bib0270","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/nbt0714-605a","article-title":"Sanofi's dengue vaccine first to complete phase 3","volume":"32","author":"Sinha","year":"2014","journal-title":"Nat Biotechnol"},{"issue":"9\u201310","key":"10.1016\/j.vaccine.2015.12.040_bib0275","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/j.vaccine.2003.09.019","article-title":"Cost-effectiveness of a pediatric dengue vaccine","volume":"22","author":"Shepard","year":"2004","journal-title":"Vaccine"},{"issue":"5","key":"10.1016\/j.vaccine.2015.12.040_bib0280","doi-asserted-by":"crossref","first-page":"764","DOI":"10.4269\/ajtmh.2011.10-0624","article-title":"Economic value of dengue vaccine in Thailand","volume":"84","author":"Lee","year":"2011","journal-title":"Am J Trop Med Hyg"},{"issue":"12","key":"10.1016\/j.vaccine.2015.12.040_bib0285","doi-asserted-by":"crossref","first-page":"e1426","DOI":"10.1371\/journal.pntd.0001426","article-title":"Economic impact of dengue illness and the cost-effectiveness of future vaccination programs in Singapore","volume":"5","author":"Carrasco","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"issue":"37","key":"10.1016\/j.vaccine.2015.12.040_bib0290","doi-asserted-by":"crossref","first-page":"3957","DOI":"10.1016\/j.vaccine.2013.06.036","article-title":"Dengue dynamics and vaccine cost-effectiveness in Brazil","volume":"31","author":"Durham","year":"2013","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0295","doi-asserted-by":"crossref","first-page":"f1049","DOI":"10.1136\/bmj.f1049","article-title":"Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement","volume":"346","author":"Husereau","year":"2013","journal-title":"BMJ"},{"issue":"Suppl. 18","key":"10.1016\/j.vaccine.2015.12.040_bib0300","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1590\/S0036-46652012000700008","article-title":"Designing a vaccination strategy against dengue","volume":"54","author":"Amaku","year":"2012","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0305","unstructured":"Pan American Health Organization. Dengue Regional Information: Number of Cases. Available at http:\/\/www.paho.org\/hq\/index.php?option=com_topics&view=article&id=1&Itemid=40734&lang=en."},{"issue":"6","key":"10.1016\/j.vaccine.2015.12.040_bib0310","doi-asserted-by":"crossref","first-page":"e1180","DOI":"10.1371\/journal.pntd.0001180","article-title":"Age-specificity of clinical dengue during primary and secondary infections","volume":"5","author":"Thai","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"issue":"3","key":"10.1016\/j.vaccine.2015.12.040_bib0315","first-page":"219","article-title":"Delayed vaccine schedule and missed opportunities for vaccination in children up to 24 months. A multicenter study","volume":"109","author":"Gentile","year":"2011","journal-title":"Arch Argent Pediatr"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0320","unstructured":"Ciudad Aut\u00f3noma de Buenos Aires. Anexo del bolet\u00edn oficial N\u00b0 4354. Available at http:\/\/boletinoficial.buenosaires.gob.ar\/documentos\/boletines\/2014\/03\/20140310ax.pdf."},{"issue":"4","key":"10.1016\/j.vaccine.2015.12.040_bib0325","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s40273-014-0132-3","article-title":"How to estimate productivity costs in economic evaluations","volume":"32","author":"Krol","year":"2014","journal-title":"Pharmacoeconomics"},{"issue":"9853","key":"10.1016\/j.vaccine.2015.12.040_bib0330","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1016\/S0140-6736(12)61428-7","article-title":"Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial","volume":"380","author":"Sabchareon","year":"2012","journal-title":"Lancet"},{"issue":"32","key":"10.1016\/j.vaccine.2015.12.040_bib0335","doi-asserted-by":"crossref","first-page":"4892","DOI":"10.1016\/j.vaccine.2012.02.064","article-title":"Cost of production of live attenuated dengue vaccines: a case study of the Instituto Butantan, Sao Paulo, Brazil","volume":"30","author":"Mahoney","year":"2012","journal-title":"Vaccine"},{"issue":"39","key":"10.1016\/j.vaccine.2015.12.040_bib0340","doi-asserted-by":"crossref","first-page":"4885","DOI":"10.1016\/j.vaccine.2014.07.008","article-title":"Safety, immunogenicity and efficacy of a recombinant tetravalent dengue vaccine: a meta-analysis of randomized trials","volume":"32","author":"da Costa","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0345","unstructured":"World Health Organization. Global burden of disease 2004 update: disability weights for diseases and conditions. Available at http:\/\/www.who.int\/healthinfo\/global_burden_disease\/GBD2004_DisabilityWeights.pdf."},{"key":"10.1016\/j.vaccine.2015.12.040_bib0350","series-title":"Cost-effectiveness analysis in health, a practical approach","author":"Muening","year":"2008"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0355","series-title":"World health report 2002: reducing risks, promoting healthy life","author":"World Health Organization","year":"2002"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0360","unstructured":"International Monitory Fund. The World Economic Outlook (WEO) database. GDP per capita (current US$). Available at http:\/\/www.imf.org\/external\/pubs\/ft\/weo\/2015\/01\/weodata\/index.aspx."},{"issue":"42","key":"10.1016\/j.vaccine.2015.12.040_bib0365","doi-asserted-by":"crossref","first-page":"7229","DOI":"10.1016\/j.vaccine.2011.06.094","article-title":"From research to phase III: preclinical, industrial and clinical development of the Sanofi Pasteur tetravalent dengue vaccine","volume":"29","author":"Guy","year":"2011","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.vaccine.2015.12.040_bib0370","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1056\/NEJMe1413146","article-title":"Preventing dengue \u2013 is the possibility now a reality?","volume":"372","author":"Thomas","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0375","series-title":"Pharmacoeconomics: 1. From theory to practice","author":"Arnold","year":"2010"},{"issue":"5","key":"10.1016\/j.vaccine.2015.12.040_bib0380","first-page":"387","article-title":"Dengue 2009: chronology of an epidemic","volume":"107","author":"Seijo","year":"2009","journal-title":"Arch Argent Pediatr"},{"issue":"35","key":"10.1016\/j.vaccine.2015.12.040_bib0385","doi-asserted-by":"crossref","first-page":"5860","DOI":"10.1016\/j.vaccine.2011.06.042","article-title":"Models of the impact of dengue vaccines: a review of current research and potential approaches","volume":"29","author":"Johansson","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0390","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1471-2334-13-25","article-title":"An approximation of herd effect due to vaccinating children against seasonal influenza \u2013 a potential solution to the incorporation of indirect effects into static models","volume":"13","author":"Van Vlaenderen","year":"2013","journal-title":"BMC Infect Dis"},{"issue":"1","key":"10.1016\/j.vaccine.2015.12.040_bib0395","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1478-7547-11-21","article-title":"A cost-effectiveness analysis of a 10-valent pneumococcal conjugate vaccine in children in six Latin American countries","volume":"11","author":"Mart\u00ed","year":"2013","journal-title":"Cost Eff Resour Alloc"},{"issue":"2","key":"10.1016\/j.vaccine.2015.12.040_bib0400","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.smim.2013.04.010","article-title":"Valuing the broader benefits of dengue vaccination, with a preliminary application to Brazil","volume":"25","author":"B\u00e4rnighausen","year":"2013","journal-title":"Semin Immunol"},{"key":"10.1016\/j.vaccine.2015.12.040_bib0405","doi-asserted-by":"crossref","first-page":"280","DOI":"10.3389\/fimmu.2014.00280","article-title":"Epidemiological risk factors associated with high global frequency of inapparent dengue virus infections","volume":"5","author":"Grange","year":"2014","journal-title":"Front Immunol"},{"issue":"7","key":"10.1016\/j.vaccine.2015.12.040_bib0410","doi-asserted-by":"crossref","first-page":"e1732","DOI":"10.1371\/journal.pntd.0001732","article-title":"Dengue infection in children in Ratchaburi, Thailand: a cohort study. I. Epidemiology of symptomatic acute dengue infection in children, 2006-2009","volume":"6","author":"Sabchareon","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"issue":"6","key":"10.1016\/j.vaccine.2015.12.040_bib0415","doi-asserted-by":"crossref","first-page":"e1679","DOI":"10.1371\/journal.pntd.0001679","article-title":"Clinical features of dengue in a large Vietnamese cohort: intrinsically lower platelet counts and greater risk for bleeding in adults than children","volume":"6","author":"Trung","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"issue":"6","key":"10.1016\/j.vaccine.2015.12.040_bib0420","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1086\/528805","article-title":"Dengue and dengue hemorrhagic fever among adults: clinical outcomes related to viremia, serotypes, and antibody response","volume":"197","author":"Guilarde","year":"2008","journal-title":"J Infect Dis"},{"issue":"5","key":"10.1016\/j.vaccine.2015.12.040_bib0425","doi-asserted-by":"crossref","first-page":"846","DOI":"10.4269\/ajtmh.2009.80.846","article-title":"Cost of dengue cases in eight countries in the Americas and Asia: a prospective study","volume":"80","author":"Suaya","year":"2009","journal-title":"Am J Trop Med Hyg"},{"issue":"9571","key":"10.1016\/j.vaccine.2015.12.040_bib0430","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1016\/S0140-6736(07)60671-0","article-title":"Burden of symptomatic dengue infection in children at primary school in Thailand: a prospective study","volume":"369A","author":"Anderson","year":"2007","journal-title":"Lancet"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X1501837X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X1501837X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T19:12:31Z","timestamp":1567451551000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X1501837X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["S0264410X1501837X"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2015.12.040","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cost-utility analysis of dengue vaccination in a country with heterogeneous risk of dengue transmission","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2015.12.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}