{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:18:54Z","timestamp":1786997934093,"version":"build-2736575974"},"reference-count":23,"publisher":"Elsevier BV","issue":"28","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.vaccine.2016.03.097","type":"journal-article","created":{"date-parts":[[2016,5,9]],"date-time":"2016-05-09T10:33:56Z","timestamp":1462790036000},"page":"3317-3323","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":55,"title":["Detection and isolation of Bluetongue virus from commercial vaccine batches"],"prefix":"10.1016","volume":"34","author":[{"given":"Velizar","family":"Bumbarov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Golender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oran","family":"Erster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yevgeny","family":"Khinich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.vaccine.2016.03.097_bib0120","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/nm0510-493","article-title":"Vaccine contamination prompts safety review","volume":"16","author":"Scudellari","year":"2010","journal-title":"Nat Med"},{"issue":"41","key":"10.1016\/j.vaccine.2016.03.097_bib0125","doi-asserted-by":"crossref","first-page":"7117","DOI":"10.1016\/j.vaccine.2011.05.071","article-title":"Ensuring the safety of vaccine cell substrates by massively parallel sequencing of the transcriptome","volume":"29","author":"Onions","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2016.03.097_bib0130","unstructured":"Office of the Federal Register. Code of Federal Regulations, 9 CFR and 21 CFR part 630 (Additional Standards for Viral Vaccines). 1996 and earlier versions. Available at: http:\/\/www.gpo.gov\/fdsys\/pkg\/CFR-2001-title9-vol1\/pdf\/CFR-2001-title9-vol1-sec113-47.pdf [accessed July 2013]."},{"issue":"41","key":"10.1016\/j.vaccine.2016.03.097_bib0135","first-page":"7117","article-title":"Identification and characterization of avian retroviruses in chicken embryo-derived yellow fever vaccines: investigation of transmission to vaccine recipients","volume":"29","author":"Hussain","year":"2011","journal-title":"J Virol"},{"issue":"24","key":"10.1016\/j.vaccine.2016.03.097_bib0140","doi-asserted-by":"crossref","first-page":"2916","DOI":"10.1016\/j.vaccine.2014.02.021","article-title":"Systematic evaluation of in vitro and in vivo adventitious virus assays for the detection of viral contamination of cell banks and biological products","volume":"32","author":"Gombold","year":"2014","journal-title":"Vaccine"},{"issue":"5","key":"10.1016\/j.vaccine.2016.03.097_bib0145","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1128\/JCM.03146-12","article-title":"Detection of avian retroviruses in vaccines by amplification on DF-1 cells with immunostaining and fluorescent product-enhanced reverse transcriptase endpoint methods","volume":"51","author":"Birmingham","year":"2013","journal-title":"J Clin Microbiol"},{"issue":"12","key":"10.1016\/j.vaccine.2016.03.097_bib0150","doi-asserted-by":"crossref","first-page":"6033","DOI":"10.1128\/JVI.02690-09","article-title":"Viral nucleic acids in live-attenuated vaccines: detection of minority variants and an adventitious virus","volume":"84","author":"Victoria","year":"2010","journal-title":"J Virol"},{"issue":"1","key":"10.1016\/j.vaccine.2016.03.097_bib0155","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1001\/jama.2010.863","article-title":"FDA: benefits of rotavirus vaccination outweigh potential contamination risk","volume":"304","author":"Kuehn","year":"2010","journal-title":"JAMA"},{"issue":"18","key":"10.1016\/j.vaccine.2016.03.097_bib0160","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1016\/j.vaccine.2014.02.011","article-title":"Reduction of spiked porcine circovirus during the manufacture of a Vero cell-derived vaccine","volume":"32","author":"Lackner","year":"2014","journal-title":"Vaccine"},{"issue":"5","key":"10.1016\/j.vaccine.2016.03.097_bib0165","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.biologicals.2014.07.003","article-title":"Adventitious agents in viral vaccines: lessons learned from 4 case studies","volume":"42","author":"Petricciani","year":"2014","journal-title":"Biologicals"},{"issue":"11","key":"10.1016\/j.vaccine.2016.03.097_bib0170","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1136\/vr.134.11.283","article-title":"Bluetongue disease in dogs associated with contaminated vaccine","volume":"134","author":"Akita","year":"1994","journal-title":"Vet Rec"},{"issue":"6701","key":"10.1016\/j.vaccine.2016.03.097_bib0175","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/26694","article-title":"The atomic structure of the bluetongue virus core","volume":"395","author":"Grimes","year":"1998","journal-title":"Nature"},{"issue":"1530","key":"10.1016\/j.vaccine.2016.03.097_bib0180","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1098\/rstb.2009.0091","article-title":"Bluetongue in Europe: past, present and future","volume":"364","author":"Wilson","year":"2009","journal-title":"Philos Trans R Soc Lond B: Biol Sci"},{"issue":"4","key":"10.1016\/j.vaccine.2016.03.097_bib0185","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.prevetmed.2009.11.007","article-title":"Financial consequences of the Dutch bluetongue serotype 8 epidemics of 2006 and 2007","volume":"93","author":"Velthuis","year":"2010","journal-title":"Prev Vet Med"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2016.03.097_bib0190","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vetmic.2012.07.007","article-title":"Bluetongue virus genetic and phenotypic diversity: towards identifying the molecular determinants that influence virulence and transmission potential","volume":"161","author":"Coetzee","year":"2012","journal-title":"Vet Microbiol"},{"issue":"2","key":"10.1016\/j.vaccine.2016.03.097_bib0195","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jviromet.2007.05.014","article-title":"Development and initial evaluation of a real-time RT-PCR assay to detect bluetongue virus genome segment 1","volume":"145","author":"Shaw","year":"2007","journal-title":"J Virol Methods"},{"key":"10.1016\/j.vaccine.2016.03.097_bib0200","first-page":"307","article-title":"Isolation and propagation of bluetongue virus on embryonating chicken eggs","volume":"178","author":"Goldsmit","year":"1985","journal-title":"Prog Clin Biol Res"},{"key":"10.1016\/j.vaccine.2016.03.097_bib0205","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1177\/104063879400600201","article-title":"Diagnostic analysis of the prolonged bluetongue virus RNA presence found in the blood of naturally infected cattle and experimentally infected sheep","volume":"6","author":"Katz","year":"1994","journal-title":"J Vet Diagn Invest"},{"key":"10.1016\/j.vaccine.2016.03.097_bib0210","series-title":"Bluetongue and Epizootic haemorrhagic disease","author":"OIE terestioal Manual","year":"2014"},{"key":"10.1016\/j.vaccine.2016.03.097_bib0215","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1093\/nar\/gkh340","article-title":"MUSCLE: multiple sequence alignment with high accuracy and high throughput","volume":"32","author":"Edgar","year":"2004","journal-title":"Nucl Acids Res"},{"issue":"12","key":"10.1016\/j.vaccine.2016.03.097_bib0220","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1093\/molbev\/mst197","article-title":"MEGA6: molecular evolutionary genetics analysis version 6.0","volume":"30","author":"Tamura","year":"2013","journal-title":"Mol Biol Evol"},{"issue":"26","key":"10.1016\/j.vaccine.2016.03.097_bib0225","doi-asserted-by":"crossref","first-page":"4299","DOI":"10.1016\/j.vaccine.2011.04.049","article-title":"Contamination in bluetongue virus challenge experiments","volume":"29","author":"Eschbaumer","year":"2011","journal-title":"Vaccine"},{"issue":"18","key":"10.1016\/j.vaccine.2016.03.097_bib0230","doi-asserted-by":"crossref","first-page":"10399","DOI":"10.1128\/JVI.01641-14","article-title":"Virus and host factors affecting the clinical outcome of bluetongue virus infection","volume":"88","author":"Caporale","year":"2014","journal-title":"J Virol"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X16300949?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X16300949?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T02:22:30Z","timestamp":1536718950000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X16300949"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":23,"journal-issue":{"issue":"28","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["S0264410X16300949"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2016.03.097","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Detection and isolation of Bluetongue virus from commercial vaccine batches","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2016.03.097","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}