{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T14:50:10Z","timestamp":1788792610791,"version":"build-2803163510"},"reference-count":58,"publisher":"Elsevier BV","issue":"39","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5R01AI098339"],"award-info":[{"award-number":["5R01AI098339"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5T32AI007401"],"award-info":[{"award-number":["5T32AI007401"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.vaccine.2016.08.010","type":"journal-article","created":{"date-parts":[[2016,8,8]],"date-time":"2016-08-08T19:27:18Z","timestamp":1470684438000},"page":"4712-4717","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model"],"prefix":"10.1016","volume":"34","author":[{"given":"Beth C.","family":"Holbrook","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Ralph B.","family":"D\u2019Agostino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Griffith D.","family":"Parks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha A.","family":"Alexander-Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2016.08.010_b0005","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1097\/00006454-199711000-00012","article-title":"Influenza virus infections in infants","volume":"16","author":"Glezen","year":"1997","journal-title":"Pediatr. Infect. Dis. J."},{"key":"10.1016\/j.vaccine.2016.08.010_b0010","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1056\/NEJMoa054869","article-title":"The underrecognized burden of influenza in young children","volume":"355","author":"Poehling","year":"2006","journal-title":"New Engl. J. Med."},{"key":"10.1016\/j.vaccine.2016.08.010_b0015","first-page":"7","article-title":"Factors associated with intention to receive Influenza and Tetanus, Diphtheria, and Acellular Pertussis (Tdap) vaccines during pregnancy: a focus on vaccine hesitancy and perceptions of disease severity and vaccine safety","author":"Chamberlain","year":"2015","journal-title":"PLoS Curr."},{"key":"10.1016\/j.vaccine.2016.08.010_b0020","doi-asserted-by":"publisher","first-page":"3571","DOI":"10.1016\/j.vaccine.2015.05.048","article-title":"Improving influenza and Tdap vaccination during pregnancy: a cluster-randomized trial of a multi-component antenatal vaccine promotion package in late influenza season","volume":"33","author":"Chamberlain","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2016.08.010_b0025","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1542\/peds.87.6.823","article-title":"Immunization of high-risk infants younger than 18 months of age with split-product influenza vaccine","volume":"87","author":"Groothuis","year":"1991","journal-title":"Pediatrics"},{"key":"10.1016\/j.vaccine.2016.08.010_b0030","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.1086\/587643","article-title":"Safety and immunogenicity of trivalent inactivated influenza vaccine in infants","volume":"197","author":"Halasa","year":"2008","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.vaccine.2016.08.010_b0035","doi-asserted-by":"publisher","first-page":"5363","DOI":"10.4049\/jimmunol.1401410","article-title":"Vaccines against respiratory viral pathogens for use in neonates: opportunities and challenges","volume":"193","author":"Alexander-Miller","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0040","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1097\/QCO.0b013e32835fb8bf","article-title":"Early life response to infection","volume":"26","author":"Ghazal","year":"2013","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.vaccine.2016.08.010_b0045","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.it.2009.09.002","article-title":"Neonatal immunity: faulty T-helpers and the shortcomings of dendritic cells","volume":"30","author":"Zaghouani","year":"2009","journal-title":"Trends Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0050","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.4049\/jimmunol.166.3.2141","article-title":"Deficient IL-12(p35) gene expression by dendritic cells derived from neonatal monocytes","volume":"166","author":"Goriely","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0055","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1046\/j.1365-2249.2002.01817.x","article-title":"Neonatal dendritic cells are intrinsically biased against Th-1 immune responses","volume":"128","author":"Langrish","year":"2002","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0060","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.jaut.2003.08.003","article-title":"Impaired responses to toll-like receptor 4 and toll-like receptor 3 ligands in human cord blood","volume":"21","author":"De Wit","year":"2003","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.vaccine.2016.08.010_b0065","doi-asserted-by":"publisher","first-page":"10006","DOI":"10.1073\/pnas.89.21.10006","article-title":"Phenotypic and functional immaturity of human umbilical cord blood T lymphocytes","volume":"89","author":"Harris","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.vaccine.2016.08.010_b0070","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.bbmt.2005.10.027","article-title":"Impaired allogeneic activation and T-helper 1 differentiation of human cord blood naive CD4 T cells","volume":"12","author":"Chen","year":"2006","journal-title":"Biol. Blood Marrow Transplant."},{"key":"10.1016\/j.vaccine.2016.08.010_b0075","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1172\/JCI117677","article-title":"Diminished expression of CD40 ligand by activated neonatal T cells","volume":"95","author":"Nonoyama","year":"1995","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.vaccine.2016.08.010_b0080","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.4049\/jimmunol.163.5.2416","article-title":"Inefficient phospholipase C activation and reduced Lck expression characterize the signaling defect of umbilical cord T lymphocytes","volume":"163","author":"Miscia","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0085","doi-asserted-by":"publisher","first-page":"2682","DOI":"10.4049\/jimmunol.1202534","article-title":"Human neonatal naive CD4+ T cells have enhanced activation-dependent signaling regulated by the microRNA miR-181a","volume":"190","author":"Palin","year":"2013","journal-title":"J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0090","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.4049\/jimmunol.1203288","article-title":"Neonatal follicular Th cell responses are impaired and modulated by IL-4","volume":"191","author":"Debock","year":"2013","journal-title":"J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0095","doi-asserted-by":"publisher","first-page":"2824","DOI":"10.4049\/jimmunol.170.6.2824","article-title":"Unresponsiveness to lymphoid-mediated signals at the neonatal follicular dendritic cell precursor level contributes to delayed germinal center induction and limitations of neonatal antibody responses to T-dependent antigens","volume":"170","author":"Pihlgren","year":"2003","journal-title":"J. Immunol."},{"issue":"Suppl 1","key":"10.1016\/j.vaccine.2016.08.010_b0100","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.1016\/j.jcpa.2007.04.004","article-title":"The challenges of vaccine responses in early life: selected examples","volume":"137","author":"Siegrist","year":"2007","journal-title":"J. Comp. Pathol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0105","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1586\/1744666X.2014.942288","article-title":"Immune responses in neonates","volume":"10","author":"Basha","year":"2014","journal-title":"Expert Rev. Clin. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0110","doi-asserted-by":"publisher","first-page":"2755","DOI":"10.1182\/blood-2007-09-110858","article-title":"APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells","volume":"111","author":"Belnoue","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.vaccine.2016.08.010_b0115","doi-asserted-by":"publisher","first-page":"e454","DOI":"10.1542\/neo.6-10-e454","article-title":"The neonatal adaptive immune system","volume":"6","author":"Randolph","year":"2005","journal-title":"NeoReviews"},{"key":"10.1016\/j.vaccine.2016.08.010_b0120","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1038\/nri1394","article-title":"Neonatal adaptive immunity comes of age","volume":"4","author":"Adkins","year":"2004","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0125","doi-asserted-by":"publisher","first-page":"5677","DOI":"10.4049\/jimmunol.1002156","article-title":"Flagellin as an adjuvant: cellular mechanisms and potential","volume":"185","author":"Mizel","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0130","doi-asserted-by":"publisher","first-page":"4103","DOI":"10.1016\/j.vaccine.2009.07.058","article-title":"Salmonella flagellins are potent adjuvants for intranasally administered whole inactivated influenza vaccine","volume":"28","author":"Skountzou","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2016.08.010_b0135","doi-asserted-by":"publisher","first-page":"5165","DOI":"10.4049\/jimmunol.170.10.5165","article-title":"The Toll-like receptor 5 stimulus bacterial flagellin induces maturation and chemokine production in human dendritic cells","volume":"170","author":"Means","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0140","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.mad.2008.01.009","article-title":"Mucosal adjuvant activity of flagellin in aged mice","volume":"129","author":"Bates","year":"2008","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.vaccine.2016.08.010_b0145","doi-asserted-by":"publisher","first-page":"7539","DOI":"10.4049\/jimmunol.0804225","article-title":"Direct stimulation of tlr5+\/+ CD11c+ cells is necessary for the adjuvant activity of flagellin","volume":"182","author":"Bates","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0150","doi-asserted-by":"publisher","first-page":"55","DOI":"10.4049\/jimmunol.182.1.55","article-title":"Activated human neonatal CD8+ T cells are subject to immunomodulation by direct TLR2 or TLR5 stimulation","volume":"182","author":"McCarron","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0155","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/j.immuni.2014.08.009","article-title":"TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination","volume":"41","author":"Oh","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.vaccine.2016.08.010_b0160","doi-asserted-by":"publisher","first-page":"1684","DOI":"10.1002\/eji.200636181","article-title":"TLR2 engagement on CD8 T cells lowers the threshold for optimal antigen-induced T cell activation","volume":"36","author":"Cottalorda","year":"2006","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0165","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1002\/eji.200323797","article-title":"Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines","volume":"33","author":"Edwards","year":"2003","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0170","doi-asserted-by":"publisher","first-page":"7291","DOI":"10.1128\/JVI.00549-15","article-title":"Inclusion of flagellin during vaccination against influenza enhances recall responses in nonhuman primate neonates","volume":"89","author":"Kim","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0175","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1128\/CVI.00374-14","article-title":"Influenza virus-specific neutralizing IgM antibodies persist for a lifetime","volume":"21","author":"Skountzou","year":"2014","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0180","doi-asserted-by":"crossref","first-page":"195","DOI":"10.7883\/yoken.JJID.2005.195","article-title":"Mechanisms of broad cross-protection provided by influenza virus infection and their application to vaccines","volume":"58","author":"Tamura","year":"2005","journal-title":"Jpn. J. Infect. Dis."},{"key":"10.1016\/j.vaccine.2016.08.010_b0185","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/978-1-61779-621-0_3","article-title":"Influenza virus titration, antigenic characterization, and serological methods for antibody detection","volume":"865","author":"Klimov","year":"2012","journal-title":"Method Mol. Biol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0190","doi-asserted-by":"publisher","first-page":"5525","DOI":"10.1128\/IAI.68.10.5525-5529.2000","article-title":"High-affinity interaction between gram-negative flagellin and a cell surface polypeptide results in human monocyte activation","volume":"68","author":"McDermott","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vaccine.2016.08.010_b0195","doi-asserted-by":"publisher","first-page":"11531","DOI":"10.1073\/pnas.0914994107","article-title":"Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus","volume":"107","author":"Manicassamy","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.vaccine.2016.08.010_b0200","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.virol.2014.12.007","article-title":"Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection","volume":"476","author":"Holbrook","year":"2015","journal-title":"Virology"},{"key":"10.1016\/j.vaccine.2016.08.010_b0205","doi-asserted-by":"publisher","first-page":"35","DOI":"10.2165\/00003495-200060010-00004","article-title":"Humoral immune response to influenza vaccination in patients from high risk groups","volume":"60","author":"Brydak","year":"2000","journal-title":"Drugs"},{"key":"10.1016\/j.vaccine.2016.08.010_b0210","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/0022-1759(88)90196-2","article-title":"The measurement of relative antibody-affinity by Elisa using thiocyanate elution","volume":"106","author":"Macdonald","year":"1988","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.vaccine.2016.08.010_b0215","doi-asserted-by":"publisher","first-page":"733","DOI":"10.7326\/0003-4819-155-11-201112060-00005","article-title":"Maternal immune response and neonatal seroprotection from a single dose of a monovalent nonadjuvanted 2009 influenza A(H1N1) vaccine: a single-group trial","volume":"155","author":"Tsatsaris","year":"2011","journal-title":"Ann. Int. Med."},{"key":"10.1016\/j.vaccine.2016.08.010_b0220","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1128\/IAI.74.2.1113-1120.2006","article-title":"Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestis","volume":"74","author":"Honko","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.vaccine.2016.08.010_b0225","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.vaccine.2007.10.062","article-title":"Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin","volume":"26","author":"Huleatt","year":"2008","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2016.08.010_b0230","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1128\/CVI.00333-08","article-title":"Flagellin-F1-V fusion protein is an effective plague vaccine in mice and two species of nonhuman primates","volume":"16","author":"Mizel","year":"2009","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0235","doi-asserted-by":"publisher","first-page":"4897","DOI":"10.1016\/j.vaccine.2011.05.001","article-title":"Induction of a potent immune response in the elderly using the TLR-5 agonist, flagellin, with a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125, STF2.HA1 SI)","volume":"29","author":"Taylor","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2016.08.010_b0240","doi-asserted-by":"publisher","first-page":"11813","DOI":"10.1128\/JVI.01076-08","article-title":"Incorporation of membrane-anchored flagellin into influenza virus-like particles enhances the breadth of immune responses","volume":"82","author":"Wang","year":"2008","journal-title":"J. Virol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0245","first-page":"2","article-title":"Enhanced mucosal immune responses to HIV virus-like particles containing a membrane-anchored adjuvant","author":"Vassilieva","year":"2011","journal-title":"MBio."},{"key":"10.1016\/j.vaccine.2016.08.010_b0250","doi-asserted-by":"publisher","first-page":"e0148701","DOI":"10.1371\/journal.pone.0148701","article-title":"Flagellin encoded in gene-based vector vaccines is a route-dependent immune adjuvant","volume":"11","author":"Rady","year":"2016","journal-title":"PLoS ONE"},{"key":"10.1016\/j.vaccine.2016.08.010_b0255","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1007\/s10482-013-0075-2","article-title":"Utilizing bacterial flagellins against infectious diseases and cancers","volume":"105","author":"Tarahomjoo","year":"2014","journal-title":"Antonie Van Leeuwenhoek"},{"key":"10.1016\/j.vaccine.2016.08.010_b0260","doi-asserted-by":"publisher","first-page":"5761","DOI":"10.1016\/j.vaccine.2012.06.086","article-title":"Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response","volume":"30","author":"Taylor","year":"2012","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2016.08.010_b0265","doi-asserted-by":"publisher","first-page":"5145","DOI":"10.1016\/j.vaccine.2011.05.041","article-title":"Safety and immunogenicity of a recombinant M2e-flagellin influenza vaccine (STF2.4xM2e) in healthy adults","volume":"29","author":"Turley","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2016.08.010_b0270","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1038\/nri2508","article-title":"B-cell responses to vaccination at the extremes of age","volume":"9","author":"Siegrist","year":"2009","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0275","doi-asserted-by":"publisher","first-page":"65","DOI":"10.3389\/fimmu.2014.00065","article-title":"Cytokine-mediated regulation of plasma cell generation: IL-21 takes center stage","volume":"5","author":"Moens","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0280","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.4049\/jimmunol.1000115","article-title":"TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3\u2212CD127+ immune cells in spleen and mucosa","volume":"185","author":"Van Maele","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0285","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1046\/j.1365-2249.1997.3631264.x","article-title":"Somatic hypermutation of immunoglobulin genes in human neonates","volume":"108","author":"Ridings","year":"1997","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.vaccine.2016.08.010_b0290","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1046\/j.1365-2249.1998.00694.x","article-title":"Somatic mutation of immunoglobulin V(H)6 genes in human infants","volume":"114","author":"Ridings","year":"1998","journal-title":"Clin. Exp. Immunol."}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X16306673?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X16306673?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T19:38:28Z","timestamp":1718739508000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X16306673"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":58,"journal-issue":{"issue":"39","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S0264410X16306673"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2016.08.010","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2016.08.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}