{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T03:02:34Z","timestamp":1780455754527,"version":"3.54.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"46","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"J. Kleberg, Jr. and Helen C. Kleberg Foundation"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.vaccine.2016.09.044","type":"journal-article","created":{"date-parts":[[2016,9,24]],"date-time":"2016-09-24T08:10:15Z","timestamp":1474704615000},"page":"5479-5482","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Supramolecular peptide hydrogel adjuvanted subunit vaccine elicits protective antibody responses against West Nile virus"],"prefix":"10.1016","volume":"34","author":[{"given":"Brian M.","family":"Friedrich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.C.","family":"Beasley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jai S.","family":"Rudra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.vaccine.2016.09.044_b0005","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1038\/nm1209","article-title":"Vaccines: past, present and future","volume":"11","author":"Plotkin","year":"2005","journal-title":"Nat Med"},{"issue":"19","key":"10.1016\/j.vaccine.2016.09.044_b0010","doi-asserted-by":"crossref","first-page":"3752","DOI":"10.1016\/j.vaccine.2007.01.111","article-title":"Vaccine adjuvants revisited","volume":"25","author":"Aguilar","year":"2007","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.vaccine.2016.09.044_b0015","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1586\/erv.09.160","article-title":"Advances in the design and delivery of peptide subunit vaccines with a focus on Toll-like receptor agonists","volume":"9","author":"Black","year":"2010","journal-title":"Expert Rev Vaccines"},{"issue":"7","key":"10.1016\/j.vaccine.2016.09.044_b0020","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1586\/erv.11.48","article-title":"Current adjuvants and new perspectives in vaccine formulation","volume":"10","author":"Montomoli","year":"2011","journal-title":"Expert Rev Vaccines"},{"issue":"11","key":"10.1016\/j.vaccine.2016.09.044_b0025","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1038\/nmat3775","article-title":"Engineering synthetic vaccines using cues from natural immunity","volume":"12","author":"Irvine","year":"2013","journal-title":"Nat Mater"},{"issue":"7272","key":"10.1016\/j.vaccine.2016.09.044_b0030","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/nature08604","article-title":"Materials engineering for immunomodulation","volume":"462","author":"Hubbell","year":"2009","journal-title":"Nature"},{"issue":"17","key":"10.1016\/j.vaccine.2016.09.044_b0035","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.2217\/nnm.14.187","article-title":"Recent advances in peptide-based subunit nanovaccines","volume":"9","author":"Skwarczynski","year":"2014","journal-title":"Nanomedicine"},{"key":"10.1016\/j.vaccine.2016.09.044_b0040","doi-asserted-by":"crossref","first-page":"778","DOI":"10.4161\/hv.27332","article-title":"Recent progress in adjuvant discovery for peptide-based subunit vaccines","volume":"10","author":"Azmi","year":"2014","journal-title":"Hum Vacc Immunother"},{"issue":"10","key":"10.1016\/j.vaccine.2016.09.044_b0045","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1016\/j.vaccine.2013.11.047","article-title":"Antigenic peptide nanofibers elicit adjuvant-free CD8(+) T cell responses","volume":"32","author":"Chesson","year":"2014","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.vaccine.2016.09.044_b0050","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1073\/pnas.0912124107","article-title":"A self-assembling peptide acting as an immune adjuvant","volume":"107","author":"Rudra","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"issue":"21","key":"10.1016\/j.vaccine.2016.09.044_b0055","doi-asserted-by":"crossref","first-page":"8730","DOI":"10.1021\/ja211725s","article-title":"A totally synthetic, self-assembling, adjuvant-free MUC1 glycopeptide vaccine for cancer therapy","volume":"134","author":"Huang","year":"2012","journal-title":"J Am Chem Soc"},{"issue":"27","key":"10.1016\/j.vaccine.2016.09.044_b0060","doi-asserted-by":"crossref","first-page":"6476","DOI":"10.1016\/j.biomaterials.2012.05.041","article-title":"Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope","volume":"33","author":"Rudra","year":"2012","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.vaccine.2016.09.044_b0065","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/bip.21326","article-title":"Fibrillar peptide gels in biotechnology and biomedicine","volume":"94","author":"Jung","year":"2010","journal-title":"Biopolymers"},{"issue":"3","key":"10.1016\/j.vaccine.2016.09.044_b0070","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/bip.22058","article-title":"Self-assembly of amphipathic beta-sheet peptides: insights and applications","volume":"98","author":"Bowerman","year":"2012","journal-title":"Biopolymers"},{"issue":"5","key":"10.1016\/j.vaccine.2016.09.044_b0075","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1128\/JVI.01886-10","article-title":"Immunodominance and functional activities of antibody responses to inactivated West Nile virus and recombinant subunit vaccines in mice","volume":"85","author":"Zlatkovic","year":"2011","journal-title":"J Virol"},{"issue":"5","key":"10.1016\/j.vaccine.2016.09.044_b0080","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.4049\/jimmunol.178.5.2699","article-title":"Immunization of flavivirus West Nile recombinant envelope domain III protein induced specific immune response and protection against West Nile virus infection","volume":"178","author":"Chu","year":"2007","journal-title":"J Immunol"},{"key":"10.1016\/j.vaccine.2016.09.044_b0085","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.virol.2005.02.011","article-title":"Differential expression of domain III neutralizing epitopes on the envelope proteins of West Nile virus strains","volume":"335","author":"Li","year":"2005","journal-title":"Virology"},{"issue":"9","key":"10.1016\/j.vaccine.2016.09.044_b0090","doi-asserted-by":"crossref","first-page":"4757","DOI":"10.1128\/JVI.02861-15","article-title":"Recovery of West Nile virus envelope protein domain III chimeras with altered antigenicity and mouse virulence","volume":"90","author":"McAuley","year":"2016","journal-title":"J Virol"},{"issue":"34","key":"10.1016\/j.vaccine.2016.09.044_b0095","doi-asserted-by":"crossref","first-page":"8776","DOI":"10.1016\/j.biomaterials.2013.07.063","article-title":"The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation","volume":"34","author":"Chen","year":"2013","journal-title":"Biomaterials"},{"issue":"8","key":"10.1016\/j.vaccine.2016.09.044_b0100","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1002\/adhm.201200435","article-title":"A self-adjuvanting supramolecular vaccine carrying a folded protein antigen","volume":"2","author":"Hudalla","year":"2013","journal-title":"Adv Healthc Mater"},{"key":"10.1016\/j.vaccine.2016.09.044_b0105","doi-asserted-by":"crossref","first-page":"8905","DOI":"10.1039\/c1sm05157a","article-title":"Design of a shear-thinning recoverable peptide hydrogel from native sequences and application for influenza H1N1 vaccine adjuvant","volume":"7","author":"Huang","year":"2011","journal-title":"Soft Matter"},{"issue":"41","key":"10.1016\/j.vaccine.2016.09.044_b0110","doi-asserted-by":"crossref","first-page":"4508","DOI":"10.1016\/j.vaccine.2013.07.080","article-title":"Peptide nanofiber hydrogel adjuvanted live virus vaccine enhances cross-protective immunity to porcine reproductive and respiratory syndrome virus","volume":"31","author":"Li","year":"2013","journal-title":"Vaccine"},{"issue":"11","key":"10.1016\/j.vaccine.2016.09.044_b0115","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1002\/adfm.201505188","article-title":"Enzyme-catalyzed formation of supramolecular hydrogels as promising vaccine adjuvants","volume":"26","author":"Wang","year":"2016","journal-title":"Adv Funct Mater"},{"issue":"3","key":"10.1016\/j.vaccine.2016.09.044_b0120","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1128\/CVI.00714-14","article-title":"Vaccine self-assembling immune matrix is a new delivery platform that enhances immune responses to recombinant HBsAg in mice","volume":"22","author":"Grenfell","year":"2015","journal-title":"Clin Vaccine Immunol"},{"issue":"2","key":"10.1016\/j.vaccine.2016.09.044_b0125","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1039\/C1SM06513K","article-title":"Shear-thinning hydrogels for biomedical applications","volume":"8","author":"Guvendiren","year":"2012","journal-title":"Soft Matter"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X16308581?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X16308581?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,8]],"date-time":"2018-09-08T00:52:59Z","timestamp":1536367979000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X16308581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":25,"journal-issue":{"issue":"46","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S0264410X16308581"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2016.09.044","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Supramolecular peptide hydrogel adjuvanted subunit vaccine elicits protective antibody responses against West Nile virus","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2016.09.044","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}