{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T16:00:16Z","timestamp":1793721616862,"version":"4.6.1"},"reference-count":15,"publisher":"Elsevier BV","issue":"46","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31490601"],"award-info":[{"award-number":["31490601"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Luoyang Heluo Talent Plan"},{"name":"Technology Foundation for Selected Overseas Chinese Scholar"},{"name":"Talents Plan for Scientific and Technological Innovation in Henan Province","award":["144200510002"],"award-info":[{"award-number":["144200510002"]}]},{"name":"Science and Technology Innovation team in Henan Province"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.vaccine.2016.09.048","type":"journal-article","created":{"date-parts":[[2016,10,7]],"date-time":"2016-10-07T14:18:48Z","timestamp":1475849928000},"page":"5540-5545","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":96,"title":["Commercial vaccines provide limited protection to NADC30-like PRRSV infection"],"prefix":"10.1016","volume":"34","author":[{"given":"Xiaofei","family":"Bai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuzhou","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guobiao","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feifei","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangdong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kegong","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2016.09.048_b0005","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1016\/j.vaccine.2015.06.092","article-title":"Live porcine reproductive and respiratory syndrome virus vaccines: current status and future direction","volume":"33","author":"Renukaradhya","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2016.09.048_b0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vetimm.2015.07.003","article-title":"Innate and adaptive immunity against porcine reproductive and respiratory syndrome virus","volume":"167","author":"Loving","year":"2015","journal-title":"Vet Immunol Immunopathol"},{"key":"10.1016\/j.vaccine.2016.09.048_b0015","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1746-6148-6-30","article-title":"Pathogenesis and antigenic characterization of a new East European subtype 3 porcine reproductive and respiratory syndrome virus isolate","volume":"6","author":"Karniychuk","year":"2010","journal-title":"BMC Veter Res"},{"key":"10.1016\/j.vaccine.2016.09.048_b0020","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1099\/vir.0.000104","article-title":"Evolutionary diversification of type 2 porcine reproductive and respiratory syndrome virus","volume":"96","author":"Brar","year":"2015","journal-title":"J General Virol"},{"key":"10.1016\/j.vaccine.2016.09.048_b0025","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1007\/s00705-016-2883-y","article-title":"Pathogenicity comparison between highly pathogenic and NADC30-like porcine reproductive and respiratory syndrome virus","volume":"161","author":"Sun","year":"2016","journal-title":"Arch Virol"},{"key":"10.1016\/j.vaccine.2016.09.048_b0030","doi-asserted-by":"crossref","first-page":"10712","DOI":"10.1128\/JVI.01446-15","article-title":"Importation and recombination are responsible for the latest emergence of highly pathogenic porcine reproductive and respiratory syndrome virus in China","volume":"89","author":"Zhao","year":"2015","journal-title":"J Virol"},{"key":"10.1016\/j.vaccine.2016.09.048_b0035","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.3201\/eid2112.150360","article-title":"NADC30-like strain of porcine reproductive and respiratory syndrome virus, China","volume":"21","author":"Zhou","year":"2015","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.vaccine.2016.09.048_b0040","doi-asserted-by":"crossref","first-page":"e526","DOI":"10.1371\/journal.pone.0000526","article-title":"Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmark","volume":"2","author":"Tian","year":"2007","journal-title":"PLoS ONE"},{"key":"10.1016\/j.vaccine.2016.09.048_b0045","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1016\/j.vaccine.2015.03.094","article-title":"Construction of a triple gene-deleted Chinese Pseudorabies virus variant and its efficacy study as a vaccine candidate on suckling piglets","volume":"33","author":"Zhang","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2016.09.048_b0050","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1146\/annurev-animal-022114-111025","article-title":"Porcine reproductive and respiratory syndrome virus (PRRSV): pathogenesis and interaction with the immune system","volume":"4","author":"Lunney","year":"2016","journal-title":"Annu Rev Anim Biosci"},{"key":"10.1016\/j.vaccine.2016.09.048_b0055","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/tbed.12530","article-title":"Outbreak investigation of NADC30-like PRRSV in South-East China","volume":"63","author":"Li","year":"2016","journal-title":"Transbound Emerg Dis"},{"key":"10.1016\/j.vaccine.2016.09.048_b0060","doi-asserted-by":"crossref","first-page":"4508","DOI":"10.1016\/j.vaccine.2013.07.080","article-title":"Peptide nanofiber hydrogel adjuvanted live virus vaccine enhances cross-protective immunity to porcine reproductive and respiratory syndrome virus","volume":"31","author":"Li","year":"2013","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2016.09.048_b0065","doi-asserted-by":"crossref","first-page":"3518","DOI":"10.1016\/j.vaccine.2015.05.058","article-title":"Pigs immunized with Chinese highly pathogenic PRRS virus modified live vaccine are protected from challenge with North American PRRSV strain NADC-20","volume":"33","author":"Galliher-Beckley","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2016.09.048_b0070","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.vetimm.2004.09.005","article-title":"Role of neutralizing antibodies in PRRSV protective immunity","volume":"102","author":"Lopez","year":"2004","journal-title":"Vet Immunol Immunopathol"},{"key":"10.1016\/j.vaccine.2016.09.048_b0075","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1051\/vetres\/2009046","article-title":"Development of an experimental inactivated PRRSV vaccine that induces virus-neutralizing antibodies","volume":"40","author":"Vanhee","year":"2009","journal-title":"Vet Res"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X16308738?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X16308738?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T21:52:03Z","timestamp":1536357123000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X16308738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":15,"journal-issue":{"issue":"46","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S0264410X16308738"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2016.09.048","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Commercial vaccines provide limited protection to NADC30-like PRRSV infection","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2016.09.048","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}