{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T06:07:43Z","timestamp":1763705263210},"reference-count":32,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,2,7]],"date-time":"2017-02-07T00:00:00Z","timestamp":1486425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.vaccine.2017.01.074","type":"journal-article","created":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T22:30:45Z","timestamp":1486765845000},"page":"1509-1516","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["GTL001 and bivalent CyaA-based therapeutic vaccine strategies against human papillomavirus and other tumor-associated antigens induce effector and memory T-cell responses that inhibit tumor growth"],"prefix":"10.1016","volume":"35","author":[{"given":"Micha\u00ebl","family":"Esquerr\u00e9","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Momot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Goubier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Gonindard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Leung-Theung-Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yolande","family":"Misseri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Christine","family":"Bissery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2017.01.074_b0005","doi-asserted-by":"crossref","first-page":"3074","DOI":"10.1128\/JVI.69.5.3074-3083.1995","article-title":"Analysis of genomic sequences of 95 papillomavirus types: uniting typing, phylogeny, and taxonomy","volume":"69","author":"Chan","year":"1995","journal-title":"J Virol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0010","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1146\/annurev-immunol-031210-101308","article-title":"Prevention and treatment of papillomavirus-related cancers through immunization","volume":"29","author":"Frazer","year":"2011","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0015","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/j.ygyno.2010.04.002","article-title":"Potential mechanisms for HPV vaccine-induced long-term protection","volume":"118","author":"Stanley","year":"2010","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0020","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.virol.2008.10.004","article-title":"Interaction of human papillomaviruses with the host immune system: a well evolved relationship","volume":"384","author":"Frazer","year":"2009","journal-title":"Virology"},{"key":"10.1016\/j.vaccine.2017.01.074_b0025","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.immuni.2010.10.006","article-title":"Systems vaccinology","volume":"33","author":"Pulendran","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.vaccine.2017.01.074_b0030","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.immuni.2010.10.008","article-title":"From vaccines to memory and back","volume":"33","author":"Sallusto","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.vaccine.2017.01.074_b0035","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4049\/jimmunol.171.1.27","article-title":"Cutting edge: rapid in vivo killing by memory CD8 T cells","volume":"171","author":"Barber","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0040","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.virol.2008.10.006","article-title":"The human papillomavirus E7 oncoprotein","volume":"384","author":"McLaughlin-Drubin","year":"2009","journal-title":"Virology"},{"issue":"169","key":"10.1016\/j.vaccine.2017.01.074_b0045","first-page":"e1","article-title":"Regression of high-grade cervical intraepithelial neoplasia with TG4001 targeted immunotherapy","volume":"204","author":"Brun","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0050","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1078\/1438-4221-00291","article-title":"The adenylate cyclase toxin from Bordetella pertussis\u2013a novel promising vehicle for antigen delivery to dendritic cells","volume":"293","author":"Simsova","year":"2004","journal-title":"Int J Med Microbiol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0055","unstructured":"Preville X, Leclerc C, Ladant D, Timmerman B. Recombinant protein carrying human papillomavirus epitopes inserted in adenylate cyclase protein or fragment thereof. Therapeutic uses thereof. In: World Intellectual Property Organization, editor; 2005."},{"key":"10.1016\/j.vaccine.2017.01.074_b0060","doi-asserted-by":"crossref","first-page":"f4781","DOI":"10.1136\/bmj.f4781","article-title":"Developing role of HPV in cervical cancer prevention","volume":"347","author":"Kitchener","year":"2013","journal-title":"BMJ"},{"key":"10.1016\/j.vaccine.2017.01.074_b0065","doi-asserted-by":"crossref","first-page":"4157","DOI":"10.4049\/jimmunol.162.7.4157","article-title":"Therapy of murine tumors with recombinant Bordetella pertussis adenylate cyclase carrying a cytotoxic T cell epitope","volume":"162","author":"Fayolle","year":"1999","journal-title":"J Immunol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0070","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0076-6879(00)26074-6","article-title":"Bordetella pertussis adenylate cyclase toxin: a vehicle to deliver CD8-positive T-cell epitopes into antigen-presenting cells","volume":"326","author":"Guermonprez","year":"2000","journal-title":"Methods Enzymol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0075","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1002\/eji.1830230929","article-title":"Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells","volume":"23","author":"Feltkamp","year":"1993","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0080","first-page":"724","article-title":"Immunization with human papillomavirus type 16 (HPV16) oncoprotein-loaded dendritic cells as well as protein in adjuvant induces MHC class I-restricted protection to HPV16-induced tumor cells","volume":"58","author":"De Bruijn","year":"1998","journal-title":"Cancer Res"},{"key":"10.1016\/j.vaccine.2017.01.074_b0085","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1073\/pnas.95.4.1800","article-title":"Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model","volume":"95","author":"Greenstone","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.vaccine.2017.01.074_b0090","first-page":"21","article-title":"Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen","volume":"56","author":"Lin","year":"1996","journal-title":"Cancer Res"},{"key":"10.1016\/j.vaccine.2017.01.074_b0095","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1158\/0008-5472.641.65.2","article-title":"Eradication of established tumors by vaccination with recombinant Bordetella pertussis adenylate cyclase carrying the human papillomavirus 16 E7 oncoprotein","volume":"65","author":"Preville","year":"2005","journal-title":"Cancer Res"},{"key":"10.1016\/j.vaccine.2017.01.074_b0100","doi-asserted-by":"crossref","first-page":"683","DOI":"10.2217\/imt.15.29","article-title":"MAGE-A3: an immunogenic target used in clinical practice","volume":"7","author":"Esfandiary","year":"2015","journal-title":"Immunotherapy"},{"key":"10.1016\/j.vaccine.2017.01.074_b0105","doi-asserted-by":"crossref","first-page":"4697","DOI":"10.4049\/jimmunol.156.12.4697","article-title":"In vivo induction of CTL responses by recombinant adenylate cyclase of Bordetella pertussis carrying viral CD8+ T cell epitopes","volume":"156","author":"Fayolle","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0110","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1600-065X.2008.00638.x","article-title":"Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections","volume":"223","author":"Ha","year":"2008","journal-title":"Immunol Rev"},{"key":"10.1016\/j.vaccine.2017.01.074_b0115","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1038\/nri1246","article-title":"Dendritic-cell control of pathogen-driven T-cell polarization","volume":"3","author":"Kapsenberg","year":"2003","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0120","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/ni.1863","article-title":"The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors","volume":"11","author":"Kawai","year":"2010","journal-title":"Nat Immunol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0125","doi-asserted-by":"crossref","first-page":"776","DOI":"10.4049\/jimmunol.181.1.776","article-title":"Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant","volume":"181","author":"Adams","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0130","doi-asserted-by":"crossref","first-page":"2476","DOI":"10.4049\/jimmunol.174.5.2476","article-title":"Cutting edge: priming of CTL by transcutaneous peptide immunization with imiquimod","volume":"174","author":"Rechtsteiner","year":"2005","journal-title":"J Immunol"},{"issue":"Suppl 2","key":"10.1016\/j.vaccine.2017.01.074_b0135","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1365-2133.2007.08265.x","article-title":"Imiquimod: mode of action","volume":"157","author":"Schon","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0140","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1002\/eji.201344094","article-title":"Topical rather than intradermal application of the TLR7 ligand imiquimod leads to human dermal dendritic cell maturation and CD8+ T-cell cross-priming","volume":"44","author":"Fehres","year":"2014","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0145","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1097\/OLQ.0b013e31815ea8d1","article-title":"Optimal frequency of imiquimod (aldara) 5% cream for the treatment of external genital warts in immunocompetent adults: a meta-analysis","volume":"35","author":"Gotovtseva","year":"2008","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.vaccine.2017.01.074_b0150","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1084\/jem.20111171","article-title":"Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans","volume":"208","author":"Caskey","year":"2011","journal-title":"J Exp Med"},{"key":"10.1016\/j.vaccine.2017.01.074_b0155","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.4049\/jimmunol.1302974","article-title":"Antigen targeting to CD11b+ dendritic cells in association with TLR4\/TRIF signaling promotes strong CD8+ T cell responses","volume":"193","author":"Dadaglio","year":"2014","journal-title":"J Immunol"},{"key":"10.1016\/j.vaccine.2017.01.074_b0160","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0140-6736(06)68181-6","article-title":"Obstetric outcomes after conservative treatment for intraepithelial or early invasive cervical lesions: systematic review and meta-analysis","volume":"367","author":"Kyrgiou","year":"2006","journal-title":"Lancet"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X17301548?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X17301548?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T05:37:50Z","timestamp":1692682670000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X17301548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":32,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["S0264410X17301548"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2017.01.074","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"GTL001 and bivalent CyaA-based therapeutic vaccine strategies against human papillomavirus and other tumor-associated antigens induce effector and memory T-cell responses that inhibit tumor growth","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2017.01.074","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}