{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:11:40Z","timestamp":1790802700080,"version":"4.1.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"50","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.vaccine.2017.02.068","type":"journal-article","created":{"date-parts":[[2017,3,14]],"date-time":"2017-03-14T02:01:41Z","timestamp":1489456901000},"page":"7355-7362","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Meeting report: WHO consultation on Respiratory Syncytial Virus (RSV) vaccine development, Geneva, 25\u201326 April 2016"],"prefix":"10.1016","volume":"37","author":[{"given":"Birgitte K.","family":"Giersing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth A.","family":"Karron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Vekemans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Kaslow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasee S.","family":"Moorthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.vaccine.2017.02.068_b0005","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.vaccine.2015.05.093","article-title":"WHO consultation on Respiratory Syncytial Virus Vaccine Development Report from a World Health Organization Meeting held on 23\u201324 March 2015","volume":"34","author":"Modjarrad","year":"2016","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2017.02.068_b0010","unstructured":"Meeting of the Strategic Advisory Group of Experts on immunization, April 2016\u2013 conclusions and recommendations. WHO Weekly epidemiological record; 2016, No 21, 2016, 91, 265\u2013284."},{"issue":"4","key":"10.1016\/j.vaccine.2017.02.068_b0015","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1093\/oxfordjournals.aje.a120955","article-title":"Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine","volume":"89","author":"Kim","year":"1969","journal-title":"Am J Epidemiol"},{"issue":"42","key":"10.1016\/j.vaccine.2017.02.068_b0020","doi-asserted-by":"crossref","first-page":"7372","DOI":"10.1016\/j.vaccine.2007.08.014","article-title":"The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenuated, respiratory syncytial virus vaccines","volume":"25","author":"Wright","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2017.02.068_b0025","unstructured":"WHO Vaccine Pipeline Tracker. <https:\/\/docs.google.com\/spreadsheets\/d\/19otvINcayJURCMg76xWO4KvuyedYbMZDcXqbyJGdcZM\/pubhtml#>."},{"key":"10.1016\/j.vaccine.2017.02.068_b0030","unstructured":"http:\/\/ir.novavax.com\/phoenix.zhtml?c=71178&p=irol-newsArticle_Print&ID=2120087."},{"key":"10.1016\/j.vaccine.2017.02.068_b0035","unstructured":"http:\/\/ir.novavax.com\/phoenix.zhtml?c=71178&p=irol-newsArticle_Print&ID=2110287."},{"key":"10.1016\/j.vaccine.2017.02.068_b0040","unstructured":"http:\/\/ir.novavax.com\/phoenix.zhtml?c=71178&p=irol-newsArticle_Print&ID=2202271."},{"issue":"9725","key":"10.1016\/j.vaccine.2017.02.068_b0045","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/S0140-6736(10)60206-1","article-title":"Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis","volume":"375","author":"Nair","year":"2010","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.vaccine.2017.02.068_b0050","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S2213-2600(16)30042-X","article-title":"Challenges in estimatingRSV-associated mortality rates","volume":"4","author":"Zanone","year":"2016","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.vaccine.2017.02.068_b0055","unstructured":"Child health and Mortality Surveillance. <http:\/\/champshealth.org\/about-champs\/>."},{"key":"10.1016\/j.vaccine.2017.02.068_b0060","article-title":"Mortality due to respiratory syncytial virus: burden and risk factors","author":"Geoghegan","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.vaccine.2017.02.068_b0065","doi-asserted-by":"crossref","first-page":"020416","DOI":"10.7189\/jogh.05.020416","article-title":"Risk factors for respiratory syncytial virus associated with acute lower respiratory infection in children under five years: Systematic review and meta-analysis","volume":"5","author":"Shi","year":"2015","journal-title":"J Glob Health"},{"issue":"208 Suppl 3","key":"10.1016\/j.vaccine.2017.02.068_b0070","doi-asserted-by":"crossref","first-page":"S246","DOI":"10.1093\/infdis\/jit515","article-title":"Respiratory syncytial virus circulation in seven countries with Global Disease Detection Regional Centers","volume":"15","author":"Haynes","year":"2013","journal-title":"J Infect Dis"},{"issue":"7","key":"10.1016\/j.vaccine.2017.02.068_b0075","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1097\/INF.0000000000001167","article-title":"The impact of respiratory syncytial virus disease prevention on pediatric asthma","volume":"35","author":"Caballero","year":"2016","journal-title":"Pediatr Infect Dis J"},{"issue":"6","key":"10.1016\/j.vaccine.2017.02.068_b0080","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/S1473-3099(16)30059-7","article-title":"Motavizumab, RSV, and subsequent wheezing","volume":"16","author":"Sim\u00f5es","year":"2016","journal-title":"Lancet Infect Dis"},{"issue":"5","key":"10.1016\/j.vaccine.2017.02.068_b0085","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1164\/rccm.201604-0753OC","article-title":"A distinct low lung function trajectory from childhood to the fourth decade of life","volume":"194","author":"Berry","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"issue":"19","key":"10.1016\/j.vaccine.2017.02.068_b0090","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1056\/NEJMoa1211917","article-title":"Respiratory syncytial virus and recurrent wheeze in healthy preterm infants","volume":"368","author":"Blanken","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.vaccine.2017.02.068_b0095","doi-asserted-by":"crossref","DOI":"10.1164\/rccm.201609-1812OC","article-title":"Palivizumab prophylaxis in preterm infants and subsequent recurrent wheezing: 6year follow up study","author":"Mochizuki","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"issue":"12","key":"10.1016\/j.vaccine.2017.02.068_b0100","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1016\/S1473-3099(15)00247-9","article-title":"Respiratory Syncytial Virus (RSV) Prevention study group. Efficacy of motavizumab for the prevention of respiratory syncytial virus disease in healthy Native American infants: a phase 3 randomised double-blind placebo-controlled trial","volume":"15","author":"O'Brien","year":"2015","journal-title":"Lancet Infect Dis"},{"issue":"9","key":"10.1016\/j.vaccine.2017.02.068_b0105","doi-asserted-by":"crossref","first-page":"e0138018","DOI":"10.1371\/journal.pone.0138018","article-title":"Vaccine induced herd immunity for control of respiratory syncytial virus disease in a low-income country setting","volume":"10","author":"Kinyanjui","year":"2015","journal-title":"PLoS ONE"},{"issue":"2","key":"10.1016\/j.vaccine.2017.02.068_b0110","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.vaccine.2016.10.073","article-title":"Predicting the relative impacts of maternal and neonatal respiratory syncytial virus (RSV) vaccine target product profiles: a consensus modelling approach","volume":"35","author":"Pan-Ngum","year":"2017","journal-title":"Vaccine"},{"issue":"13","key":"10.1016\/j.vaccine.2017.02.068_b0115","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12916-015-0283-x","article-title":"Evaluating vaccination strategies for reducing infant respiratory syncytial virus infection in low-income settings","volume":"10","author":"Poletti","year":"2015","journal-title":"BMC Med"},{"issue":"11","key":"10.1016\/j.vaccine.2017.02.068_b0120","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1093\/infdis\/jit828","article-title":"The source of respiratory syncytial virus infection in infants: a household cohort study in rural Kenya","volume":"209","author":"Munywoki","year":"2014","journal-title":"J Infect Dis"},{"issue":"11","key":"10.1016\/j.vaccine.2017.02.068_b0125","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1093\/infdis\/jiv263","article-title":"Frequent asymptomatic respiratory syncytial virus infections during an epidemic in a rural Kenyan household Cohort","volume":"212","author":"Munywoki","year":"2015","journal-title":"J Infect Dis"},{"issue":"2","key":"10.1016\/j.vaccine.2017.02.068_b0130","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s40121-014-0046-6","article-title":"Safety and effectiveness of Palivizumab in children at high risk of serious disease due to respiratory syncytial virus infection: a systematic review","volume":"3","author":"Wegzyn","year":"2014","journal-title":"Infect Dis Ther"},{"key":"10.1016\/j.vaccine.2017.02.068_b0135","doi-asserted-by":"crossref","first-page":"290","DOI":"10.2471\/BLT.15.020515","article-title":"Hubs to spread technology and save lives","volume":"93","author":"Humphreys","year":"2015","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.vaccine.2017.02.068_b0140","article-title":"Safety, tolerability, and pharmacokinetics of the respiratory syncytial virus-prefusion F-targeting monoclonal antibody with an extended half-life, MEDI8897, in healthy adults","author":"Griffin","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"issue":"5","key":"10.1016\/j.vaccine.2017.02.068_b0145","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/S0022-3476(81)80829-3","article-title":"Risk of respiratory syncytial virus infection for infants from low-income families in relationship to age, sex, ethnic group, and maternal antibody level","volume":"98","author":"Glezen","year":"1981","journal-title":"J Pediatr"},{"key":"10.1016\/j.vaccine.2017.02.068_b0150","doi-asserted-by":"crossref","unstructured":"The PREVENT Study Group Reduction of respiratory syncytial virus hospitalization among premature infants and infants with bronchopulmonary dysplasia using respiratory syncytial virus immune globulin prophylaxis. Pediatrics 1997 ; 99(1): p. 93\u20139.","DOI":"10.1542\/peds.99.1.93"},{"key":"10.1016\/j.vaccine.2017.02.068_b0155","unstructured":"WHO Guidelines on clinical evaluation of vaccines: regulatory expectations: <http:\/\/www.who.int\/biologicals\/expert_committee\/Clinical_changes_IK_final.pdf?ua=1>."},{"issue":"41","key":"10.1016\/j.vaccine.2017.02.068_b0160","doi-asserted-by":"crossref","first-page":"4843","DOI":"10.1016\/j.vaccine.2016.07.057","article-title":"Challenges and opportunities in RSV vaccine development: Meeting report from FDA\/NIH workshop","volume":"34","author":"Roberts","year":"2016","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2017.02.068_b0165","unstructured":"FDA Briefing Document Vaccines and Related Biological Products Advisory Committee Meeting November 13, 2015. Clinical Development and Requirements for Licensure of Vaccines Intended for Use During Pregnancy to Prevent Disease in the Infant: <http:\/\/www.fda.gov\/downloads\/AdvisoryCommittees\/CommitteesMeetingMaterials\/BloodVaccinesandOtherBiologics\/VaccinesandRelatedBiologicalProductsAdvisoryCommittee\/UCM472056.pdf>."},{"key":"10.1016\/j.vaccine.2017.02.068_b0170","unstructured":"Assessing the programmatic suitability of vaccines candidates for WHO prequalification: <http:\/\/apps.who.int\/iris\/bitstream\/10665\/148168\/1\/WHO_IVB_14.10_eng.pdf?ua=1>."}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X17302931?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X17302931?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T10:50:37Z","timestamp":1759402237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X17302931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":34,"journal-issue":{"issue":"50","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["S0264410X17302931"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2017.02.068","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Meeting report: WHO consultation on Respiratory Syncytial Virus (RSV) vaccine development, Geneva, 25\u201326 April 2016","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2017.02.068","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"name":"copyright","label":"Copyright"}]}}