{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T19:44:32Z","timestamp":1780343072932,"version":"3.54.1"},"reference-count":27,"publisher":"Elsevier BV","issue":"48","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"National Key R&D Program of China","award":["2017YFD0500704"],"award-info":[{"award-number":["2017YFD0500704"]}]},{"name":"Shandong Modern Agricultural Technology & Industry System","award":["SDAIT-11-04"],"award-info":[{"award-number":["SDAIT-11-04"]}]},{"name":"Science and Technology Project for Shandong Development","award":["2014GNC111013"],"award-info":[{"award-number":["2014GNC111013"]}]},{"name":"Shandong \u201cDouble Tops\u201d Program"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.vaccine.2017.10.019","type":"journal-article","created":{"date-parts":[[2017,10,18]],"date-time":"2017-10-18T17:46:17Z","timestamp":1508348777000},"page":"6685-6690","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"PB","title":["A novel multi-variant epitope ensemble vaccine against avian leukosis virus subgroup J"],"prefix":"10.1016","volume":"35","author":[{"given":"Xiaoyu","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Defang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guihua","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Libo","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiankun","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziqiang","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2017.10.019_b0005","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1093\/bioinformatics\/btw399","article-title":"Towards the knowledge-based design of universal influenza epitope ensemble vaccines","volume":"32","author":"Qamar","year":"2016","journal-title":"Bioinformatics"},{"key":"10.1016\/j.vaccine.2017.10.019_b0010","doi-asserted-by":"crossref","unstructured":"Andrews SF, Graham BS, Mascola JR, McDermott AB. Is it possible to develop a \u201cUniversal\u201d influenza virus vaccine? Immunogenetic considerations underlying B-cell biology in the development of a pan-subtype Influenza A vaccine targeting the hemagglutinin stem. Cold Spring Harb Perspect Biol. 2017; pii: a029413. doi: 10.1101\/cshperspect.a029413.","DOI":"10.1101\/cshperspect.a029413"},{"key":"10.1016\/j.vaccine.2017.10.019_b0015","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/COH.0000000000000360","article-title":"How HIV-1 entry mechanism and broadly neutralizing antibodies guide structure-based vaccine design","volume":"12","author":"Pancera","year":"2017","journal-title":"Curr Opin HIV AIDS."},{"key":"10.1016\/j.vaccine.2017.10.019_b0020","doi-asserted-by":"crossref","first-page":"3751","DOI":"10.1016\/j.vaccine.2016.06.004","article-title":"Evaluation of a chimeric multi-epitope-based DNA vaccine against subgroup J avian leukosis virus in chickens","volume":"34","author":"Xu","year":"2016","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2017.10.019_b0025","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1099\/0022-1317-72-4-801","article-title":"A novel subgroup of exogenous avian leukosis virus in chickens","volume":"72","author":"Payne","year":"1991","journal-title":"J Gen Virol"},{"key":"10.1016\/j.vaccine.2017.10.019_b0030","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1099\/vir.0.059915-0","article-title":"Genetic mutations of avian leukosis virus subgroup J strains extended their host range","volume":"95","author":"Shen","year":"2014","journal-title":"J Gen Virol"},{"key":"10.1016\/j.vaccine.2017.10.019_b0035","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1098\/rsob.120139","article-title":"T-cell epitope vaccine design by immunoinformatics","volume":"3","author":"Patronov","year":"2013","journal-title":"Open Biol"},{"key":"10.1016\/j.vaccine.2017.10.019_b0040","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1080\/03079459808419291","article-title":"HPRS-103: a retrovirus strikes back. The emergence of subgroup J avian leukosis virus","volume":"27","author":"Payne","year":"1998","journal-title":"Avian Pathol"},{"key":"10.1016\/j.vaccine.2017.10.019_b0045","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1128\/JVI.69.2.779-784.1995","article-title":"HPRS-103 (exogenous avian leukosis virus, subgroup J) has an envgene related to those of endogenous elements EAV-0 and E51 and an Eelement found previously only in sarcoma viruses","volume":"69","author":"Bai","year":"1995","journal-title":"J Virol"},{"key":"10.1016\/j.vaccine.2017.10.019_b0050","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1586\/erv.10.77","article-title":"Back to the future: covalent epitope-based HIV vaccine development","volume":"9","author":"Paul","year":"2010","journal-title":"Expert Rev Vaccines"},{"issue":"2","key":"10.1016\/j.vaccine.2017.10.019_b0055","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1128\/MMBR.05023-11","article-title":"Viral quasispecies evolution","volume":"76","author":"Domingo","year":"2012","journal-title":"Microbiol Mol Biol Rev."},{"key":"10.1016\/j.vaccine.2017.10.019_b0060","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1292\/jvms.11-0428","article-title":"Epitope mapping of a monoclonal antibody against the Gp85 of avian leukosis virus subgroup","volume":"74","author":"Sun","year":"2012","journal-title":"J. J Vet Med Sci"},{"key":"10.1016\/j.vaccine.2017.10.019_b0065","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1007\/s00705-014-2318-6","article-title":"Identification of a novel B-cell epitope specific for avian leukosis virus subgroup J gp85 protein","volume":"160","author":"Li","year":"2015","journal-title":"Arch Virol"},{"key":"10.1016\/j.vaccine.2017.10.019_b0070","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.virusres.2015.06.024","article-title":"Evaluation of a multi-epitope subunit vaccine against avian leukosis virus subgroup J in chickens","volume":"210","author":"Xu","year":"2015","journal-title":"Virus Res"},{"key":"10.1016\/j.vaccine.2017.10.019_b0075","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.csbj.2015.11.001","article-title":"Self-assembling protein nanoparticles in the design of vaccines","volume":"14","author":"Lo'pez-Sagaseta","year":"2016","journal-title":"Comput Struct Biotechnol J"},{"key":"10.1016\/j.vaccine.2017.10.019_b0080","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/nature13404","article-title":"Accurate design of co-assembling multi-component protein nanomaterials","volume":"510","author":"King","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.vaccine.2017.10.019_b0085","doi-asserted-by":"crossref","first-page":"429","DOI":"10.3390\/vaccines3020429","article-title":"Emerging vaccine technologies","volume":"3","author":"Loomis","year":"2015","journal-title":"Vaccines"},{"key":"10.1016\/j.vaccine.2017.10.019_b0090","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.virol.2015.03.022","article-title":"Viral quasispecies","volume":"479\u2013480","author":"Andino","year":"2015","journal-title":"Virology"},{"key":"10.1016\/j.vaccine.2017.10.019_b0095","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.coi.2016.06.002","article-title":"Epitope-focused vaccine design against influenza A and B viruses","volume":"42","author":"Ren","year":"2016","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.vaccine.2017.10.019_b0100","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S1369-5274(00)00119-3","article-title":"Reverse vaccinology","volume":"3","author":"Rappuoli","year":"2000","journal-title":"Curr Opin Microbiol"},{"key":"10.1016\/j.vaccine.2017.10.019_b0105","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1016\/j.vaccine.2016.01.039","article-title":"Identification of a variant antigenic neutralizing epitope inhypervariable region 1 of avian leukosis virus subgroup","volume":"34","author":"Hou","year":"2016","journal-title":"J. Vaccine"},{"key":"10.1016\/j.vaccine.2017.10.019_b0110","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/tan.12199","article-title":"Evaluation of peptide selection approaches for epitope-based vaccine design","volume":"82","author":"Schubert","year":"2013","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.vaccine.2017.10.019_b0115","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1038\/mt.2016.3","article-title":"Novel conserved-region T-cell mosaic vaccine with high global HIV-1 coverage is recognized by protective responses in untreated infection","volume":"24","author":"Ondondo","year":"2016","journal-title":"Mol. Ther."},{"key":"10.1016\/j.vaccine.2017.10.019_b0120","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1159\/000445059","article-title":"Design and evaluation of a multi-epitope peptide of human metapneumovirus","volume":"58","author":"Li","year":"2015","journal-title":"Intervirology"},{"key":"10.1016\/j.vaccine.2017.10.019_b0125","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1080\/21645515.2015.1050572","article-title":"Preclinical development of HIvax: Human surviving highly immunogenic vaccines","volume":"11","author":"Hoffmann","year":"2015","journal-title":"Hum. Vacc. Immunother."},{"key":"10.1016\/j.vaccine.2017.10.019_b0130","doi-asserted-by":"crossref","first-page":"e2497","DOI":"10.1371\/journal.pntd.0002497","article-title":"Identification of conserved and HLA promiscuous DENV3 T-cell epitopes","volume":"7","author":"Nascimento","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.vaccine.2017.10.019_b0135","doi-asserted-by":"crossref","first-page":"e44769","DOI":"10.1371\/journal.pone.0044769","article-title":"Designing and testing broadly-protective filoviral vaccines optimized for cytotoxic T-lymphocyte epitope coverage","volume":"7","author":"Fenimore","year":"2012","journal-title":"PLoS One"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X17314159?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X17314159?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T23:26:08Z","timestamp":1603149968000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X17314159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":27,"journal-issue":{"issue":"48","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["S0264410X17314159"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2017.10.019","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A novel multi-variant epitope ensemble vaccine against avian leukosis virus subgroup J","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2017.10.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}