{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:37:27Z","timestamp":1759451847356,"version":"build-2065373602"},"reference-count":58,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,12,8]],"date-time":"2017-12-08T00:00:00Z","timestamp":1512691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.vaccine.2017.12.009","type":"journal-article","created":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T20:36:33Z","timestamp":1513110993000},"page":"484-490","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Functionality and avidity of norovirus-specific antibodies and T cells induced by GII.4 virus-like particles alone or co-administered with different genotypes"],"prefix":"10.1016","volume":"36","author":[{"given":"Maria","family":"Malm","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirsi","family":"Tamminen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suvi","family":"Heinim\u00e4ki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timo","family":"Vesikari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vesna","family":"Blazevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.vaccine.2017.12.009_b0005","doi-asserted-by":"crossref","first-page":"e1001999","DOI":"10.1371\/journal.pmed.1001999","article-title":"The vast and varied global burden of norovirus: prospects for prevention and control","volume":"13","author":"Lopman","year":"2016","journal-title":"PLoS Med"},{"issue":"12","key":"10.1016\/j.vaccine.2017.12.009_b0010","doi-asserted-by":"crossref","first-page":"e0142927","DOI":"10.1371\/journal.pone.0142927","article-title":"Aetiology-specific estimates of the global and regional incidence and mortality of diarrhoeal diseases commonly transmitted through food","volume":"10","author":"Pires","year":"2015","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.vaccine.2017.12.009_b0015","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1128\/JCM.01535-14","article-title":"Advances in laboratory methods for detection and typing of norovirus","volume":"53","author":"Vinje","year":"2015","journal-title":"J Clin Microbiol"},{"issue":"45","key":"10.1016\/j.vaccine.2017.12.009_b0020","doi-asserted-by":"crossref","first-page":"8126","DOI":"10.1016\/j.vaccine.2011.08.026","article-title":"Norovirus VLPs and rotavirus VP6 protein as combined vaccine for childhood gastroenteritis","volume":"29","author":"Blazevic","year":"2011","journal-title":"Vaccine"},{"issue":"7","key":"10.1016\/j.vaccine.2017.12.009_b0025","doi-asserted-by":"crossref","first-page":"e70409","DOI":"10.1371\/journal.pone.0070409","article-title":"Trivalent combination vaccine induces broad heterologous immune responses to norovirus and rotavirus in mice","volume":"8","author":"Tamminen","year":"2013","journal-title":"PLoS One"},{"issue":"6210","key":"10.1016\/j.vaccine.2017.12.009_b0030","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1126\/science.1257147","article-title":"Enteric bacteria promote human and mouse norovirus infection of B cells","volume":"346","author":"Jones","year":"2014","journal-title":"Science"},{"issue":"6306","key":"10.1016\/j.vaccine.2017.12.009_b0035","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1126\/science.aaf5211","article-title":"Replication of human noroviruses in stem cell-derived human enteroids","volume":"353","author":"Ettayebi","year":"2016","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.vaccine.2017.12.009_b0040","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1086\/656364","article-title":"Serological correlate of protection against norovirus-induced gastroenteritis","volume":"202","author":"Reeck","year":"2010","journal-title":"J Infect Dis"},{"issue":"23","key":"10.1016\/j.vaccine.2017.12.009_b0045","doi-asserted-by":"crossref","first-page":"12335","DOI":"10.1128\/JVI.76.23.12335-12343.2002","article-title":"Binding of Norwalk virus-like particles to ABH histo-blood group antigens is blocked by antisera from infected human volunteers or experimentally vaccinated mice","volume":"76","author":"Harrington","year":"2002","journal-title":"J Virol"},{"issue":"3","key":"10.1016\/j.vaccine.2017.12.009_b0050","doi-asserted-by":"crossref","first-page":"e1001807","DOI":"10.1371\/journal.pmed.1001807","article-title":"Broad blockade antibody responses in human volunteers after immunization with a multivalent norovirus VLP candidate vaccine: immunological analyses from a phase I clinical trial","volume":"12","author":"Lindesmith","year":"2015","journal-title":"PLoS Med"},{"issue":"6","key":"10.1016\/j.vaccine.2017.12.009_b0055","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.micinf.2014.02.010","article-title":"Comparison of human saliva and synthetic histo-blood group antigens usage as ligands in norovirus-like particle binding and blocking assays","volume":"16","author":"Uusi-Kerttula","year":"2014","journal-title":"Microbes Infect"},{"issue":"3","key":"10.1016\/j.vaccine.2017.12.009_b0060","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S1521-6616(03)00120-7","article-title":"Humoral, mucosal, and cellular immune responses to oral Norwalk virus-like particles in volunteers","volume":"108","author":"Tacket","year":"2003","journal-title":"Clin Immunol"},{"issue":"5","key":"10.1016\/j.vaccine.2017.12.009_b0065","doi-asserted-by":"crossref","first-page":"2900","DOI":"10.1128\/JVI.79.5.2900-2909.2005","article-title":"Cellular and humoral immunity following Snow Mountain virus challenge","volume":"79","author":"Lindesmith","year":"2005","journal-title":"J Virol"},{"issue":"4","key":"10.1016\/j.vaccine.2017.12.009_b0070","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1128\/JVI.02179-09","article-title":"Heterotypic humoral and cellular immune responses following Norwalk virus infection","volume":"84","author":"Lindesmith","year":"2010","journal-title":"J Virol"},{"key":"10.1016\/j.vaccine.2017.12.009_b0075","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.3389\/fmicb.2016.01570","article-title":"Norovirus-specific memory T cell responses in adult human donors","volume":"7","author":"Malm","year":"2016","journal-title":"Front Microbiol"},{"issue":"17","key":"10.1016\/j.vaccine.2017.12.009_b0080","doi-asserted-by":"crossref","first-page":"8530","DOI":"10.1128\/JVI.00727-10","article-title":"Identification of cross-reactive norovirus CD4+ T cell epitopes","volume":"84","author":"LoBue","year":"2010","journal-title":"J Virol"},{"key":"10.1016\/j.vaccine.2017.12.009_b0085","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.molimm.2016.08.009","article-title":"Type-specific and cross-reactive antibodies and T cell responses in norovirus VLP immunized mice are targeted both to conserved and variable domains of capsid VP1 protein","volume":"78","author":"Malm","year":"2016","journal-title":"Mol Immunol"},{"issue":"11","key":"10.1016\/j.vaccine.2017.12.009_b0090","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1007\/s00705-010-0768-z","article-title":"A comparison of methods for purification and concentration of norovirus GII-4 capsid virus-like particles","volume":"155","author":"Huhti","year":"2010","journal-title":"Arch Virol"},{"issue":"5","key":"10.1016\/j.vaccine.2017.12.009_b0095","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1007\/s00705-012-1565-7","article-title":"Characterization and immunogenicity of norovirus capsid-derived virus-like particles purified by anion exchange chromatography","volume":"158","author":"Huhti","year":"2013","journal-title":"Arch Virol"},{"issue":"1","key":"10.1016\/j.vaccine.2017.12.009_b0100","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1365-2567.2011.03516.x","article-title":"A comparison of immunogenicity of norovirus GII-4 virus-like particles and P-particles","volume":"135","author":"Tamminen","year":"2012","journal-title":"Immunology"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2017.12.009_b0105","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0022-1759(03)00265-5","article-title":"Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation","volume":"281","author":"Betts","year":"2003","journal-title":"J Immunol Methods"},{"issue":"11","key":"10.1016\/j.vaccine.2017.12.009_b0110","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1093\/infdis\/jiu361","article-title":"High serum levels of norovirus genotype-specific blocking antibodies correlate with protection from infection in children","volume":"210","author":"Malm","year":"2014","journal-title":"J Infect Dis"},{"issue":"6","key":"10.1016\/j.vaccine.2017.12.009_b0115","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1128\/CVI.00015-15","article-title":"Genotype considerations for virus-like particle-based bivalent norovirus vaccine composition","volume":"22","author":"Malm","year":"2015","journal-title":"Clin Vaccine Immunol"},{"issue":"23","key":"10.1016\/j.vaccine.2017.12.009_b0120","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1056\/NEJMoa1101245","article-title":"Norovirus vaccine against experimental human Norwalk Virus illness","volume":"365","author":"Atmar","year":"2011","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.vaccine.2017.12.009_b0125","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1089\/vim.2012.0082","article-title":"Pre-existing immunity to norovirus GII-4 virus-like particles does not impair de novo immune responses to norovirus GII-12 genotype","volume":"26","author":"Tamminen","year":"2013","journal-title":"Viral Immunol"},{"issue":"1","key":"10.1016\/j.vaccine.2017.12.009_b0130","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/MOG.0000000000000022","article-title":"Epidemiology of human noroviruses and updates on vaccine development","volume":"30","author":"Ramani","year":"2014","journal-title":"Curr Opin Gastroenterol"},{"issue":"4","key":"10.1016\/j.vaccine.2017.12.009_b0135","doi-asserted-by":"crossref","first-page":"e1005334","DOI":"10.1371\/journal.ppat.1005334","article-title":"Correlates of protection against norovirus infection and disease-where are we now, where do we go?","volume":"12","author":"Ramani","year":"2016","journal-title":"PLoS Pathog"},{"issue":"24","key":"10.1016\/j.vaccine.2017.12.009_b0140","doi-asserted-by":"crossref","first-page":"5220","DOI":"10.1016\/j.vaccine.2006.03.080","article-title":"Multivalent norovirus vaccines induce strong mucosal and systemic blocking antibodies against multiple strains","volume":"24","author":"LoBue","year":"2006","journal-title":"Vaccine"},{"issue":"10","key":"10.1016\/j.vaccine.2017.12.009_b0145","doi-asserted-by":"crossref","first-page":"e1002921","DOI":"10.1371\/journal.ppat.1002921","article-title":"Norovirus immunity and the great escape","volume":"8","author":"Debbink","year":"2012","journal-title":"PLoS Pathog"},{"issue":"4 Suppl","key":"10.1016\/j.vaccine.2017.12.009_b0150","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.1038\/nm1216","article-title":"Can successful vaccines teach us how to induce efficient protective immune responses?","volume":"11","author":"Lambert","year":"2005","journal-title":"Nat Med"},{"issue":"6","key":"10.1016\/j.vaccine.2017.12.009_b0155","doi-asserted-by":"crossref","first-page":"e2274","DOI":"10.1371\/journal.pntd.0002274","article-title":"Correlation between dengue-specific neutralizing antibodies and serum avidity in primary and secondary dengue virus 3 natural infections in humans","volume":"7","author":"Puschnik","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"issue":"1","key":"10.1016\/j.vaccine.2017.12.009_b0160","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/nm.1894","article-title":"Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease","volume":"15","author":"Delgado","year":"2009","journal-title":"Nat Med"},{"issue":"10","key":"10.1016\/j.vaccine.2017.12.009_b0165","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1002\/jmv.24237","article-title":"Induction of homologous and cross-reactive GII.4-specific blocking antibodies in children after GII.4 New Orleans norovirus infection","volume":"87","author":"Blazevic","year":"2015","journal-title":"J Med Virol"},{"issue":"12","key":"10.1016\/j.vaccine.2017.12.009_b0170","doi-asserted-by":"crossref","first-page":"7015","DOI":"10.1128\/JVI.03389-12","article-title":"Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses","volume":"87","author":"Tomov","year":"2013","journal-title":"J Virol"},{"issue":"12","key":"10.1016\/j.vaccine.2017.12.009_b0175","doi-asserted-by":"crossref","first-page":"e1000236","DOI":"10.1371\/journal.ppat.1000236","article-title":"Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection","volume":"4","author":"Chachu","year":"2008","journal-title":"PLoS Pathog"},{"issue":"9","key":"10.1016\/j.vaccine.2017.12.009_b0180","doi-asserted-by":"crossref","first-page":"e1003592","DOI":"10.1371\/journal.ppat.1003592","article-title":"Identification of immune and viral correlates of norovirus protective immunity through comparative study of intra-cluster norovirus strains","volume":"9","author":"Zhu","year":"2013","journal-title":"PLoS Pathog"},{"issue":"7","key":"10.1016\/j.vaccine.2017.12.009_b0185","first-page":"1653","article-title":"Norovirus vaccines: correlates of protection, challenges and limitations","volume":"12","author":"Melhem","year":"2016","journal-title":"Hum Vaccin Immunother"},{"issue":"2","key":"10.1016\/j.vaccine.2017.12.009_b0190","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/nm.2612","article-title":"Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans","volume":"18","author":"Wilkinson","year":"2012","journal-title":"Nat Med"},{"issue":"3","key":"10.1016\/j.vaccine.2017.12.009_b0195","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1111\/j.1574-6976.2012.00330.x","article-title":"Measles virus, immune control, and persistence","volume":"36","author":"Griffin","year":"2012","journal-title":"FEMS Microbiol Rev"},{"issue":"17","key":"10.1016\/j.vaccine.2017.12.009_b0200","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1089\/08892220050195847","article-title":"T cell responses to recall antigens, alloantigen, and mitogen of HIV-infected patients receiving long-term combined antiretroviral therapy","volume":"16","author":"Blazevic","year":"2000","journal-title":"AIDS Res Hum Retroviruses"},{"issue":"4","key":"10.1016\/j.vaccine.2017.12.009_b0205","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/nri2274","article-title":"T-cell quality in memory and protection: implications for vaccine design","volume":"8","author":"Seder","year":"2008","journal-title":"Nat Rev Immunol"},{"issue":"26","key":"10.1016\/j.vaccine.2017.12.009_b0210","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1016\/j.vaccine.2016.03.077","article-title":"Status of vaccine research and development for norovirus","volume":"34","author":"Riddle","year":"2016","journal-title":"Vaccine"},{"issue":"6","key":"10.1016\/j.vaccine.2017.12.009_b0215","first-page":"984","article-title":"Impact of pre-exposure history and host genetics on antibody avidity following norovirus vaccination","volume":"215","author":"Lindesmith","year":"2017","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2017.12.009_b0220","doi-asserted-by":"crossref","first-page":"153863","DOI":"10.1155\/2012\/153863","article-title":"Functional avidity: a measure to predict the efficacy of effector T cells?","volume":"2012","author":"Vigano","year":"2012","journal-title":"Clin Dev Immunol"},{"issue":"2","key":"10.1016\/j.vaccine.2017.12.009_b0225","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1365-2567.2008.03015.x","article-title":"T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity","volume":"126","author":"Stone","year":"2009","journal-title":"Immunology"},{"issue":"285","key":"10.1016\/j.vaccine.2017.12.009_b0230","doi-asserted-by":"crossref","first-page":"285ra63","DOI":"10.1126\/scitranslmed.aaa2546","article-title":"CMV-specific T cells generated from naive T cells recognize atypical epitopes and may be protective in vivo","volume":"7","author":"Hanley","year":"2015","journal-title":"Sci Transl Med"},{"issue":"341","key":"10.1016\/j.vaccine.2017.12.009_b0235","doi-asserted-by":"crossref","first-page":"341ra77","DOI":"10.1126\/scitranslmed.aaf1278","article-title":"Direct measurement of T cell receptor affinity and sequence from naive antiviral T cells","volume":"8","author":"Zhang","year":"2016","journal-title":"Sci Transl Med"},{"issue":"7","key":"10.1016\/j.vaccine.2017.12.009_b0240","doi-asserted-by":"crossref","first-page":"e41112","DOI":"10.1371\/journal.pone.0041112","article-title":"High avidity cytotoxic T lymphocytes can be selected into the memory pool but they are exquisitely sensitive to functional impairment","volume":"7","author":"Brentville","year":"2012","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.vaccine.2017.12.009_b0245","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1038\/nri819","article-title":"Cytotoxic T lymphocytes: all roads lead to death","volume":"2","author":"Barry","year":"2002","journal-title":"Nat Rev Immunol"},{"issue":"10","key":"10.1016\/j.vaccine.2017.12.009_b0250","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1371\/journal.ppat.0030144","article-title":"Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection","volume":"3","author":"Calvo-Calle","year":"2007","journal-title":"PLoS Pathog"},{"issue":"11","key":"10.1016\/j.vaccine.2017.12.009_b0255","doi-asserted-by":"crossref","first-page":"7193","DOI":"10.4049\/jimmunol.180.11.7193","article-title":"Dissociation between epitope hierarchy and immunoprevalence in CD8 responses to vaccinia virus western reserve","volume":"180","author":"Oseroff","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.vaccine.2017.12.009_b0260","first-page":"113","article-title":"Targeting skin dendritic cells to improve intradermal vaccination","volume":"351","author":"Romani","year":"2012","journal-title":"Curr Top Microbiol Immunol"},{"issue":"6673","key":"10.1016\/j.vaccine.2017.12.009_b0265","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/32588","article-title":"Dendritic cells and the control of immunity","volume":"392","author":"Banchereau","year":"1998","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.vaccine.2017.12.009_b0270","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.vaccine.2008.10.077","article-title":"Safety and efficacy of a novel microneedle device for dose sparing intradermal influenza vaccination in healthy adults","volume":"27","author":"Van Damme","year":"2009","journal-title":"Vaccine"},{"issue":"5","key":"10.1016\/j.vaccine.2017.12.009_b0275","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1089\/vim.2015.0141","article-title":"Mucosal Antibodies Induced by Intranasal but Not Intramuscular Immunization Block Norovirus GII.4 Virus-Like Particle Receptor Binding","volume":"29","author":"Tamminen","year":"2016","journal-title":"Viral Immunol"},{"issue":"3","key":"10.1016\/j.vaccine.2017.12.009_b0280","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1093\/infdis\/jiv053","article-title":"Mucosal and cellular immune responses to Norwalk virus","volume":"212","author":"Ramani","year":"2015","journal-title":"J Infect Dis"},{"issue":"4","key":"10.1016\/j.vaccine.2017.12.009_b0285","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.vaccine.2014.09.073","article-title":"Robust mucosal-homing antibody-secreting B cell responses induced by intramuscular administration of adjuvanted bivalent human norovirus-like particle vaccine","volume":"33","author":"Sundararajan","year":"2015","journal-title":"Vaccine"},{"issue":"8","key":"10.1016\/j.vaccine.2017.12.009_b0290","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1128\/CVI.00196-15","article-title":"Serological Correlates of Protection against a GII.4 Norovirus","volume":"22","author":"Atmar","year":"2015","journal-title":"Clin Vaccine Immunol"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X17317474?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X17317474?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T10:24:28Z","timestamp":1759400668000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X17317474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":58,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S0264410X17317474"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2017.12.009","relation":{},"ISSN":["0264-410X"],"issn-type":[{"type":"print","value":"0264-410X"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Functionality and avidity of norovirus-specific antibodies and T cells induced by GII.4 virus-like particles alone or co-administered with different genotypes","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2017.12.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}