{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T10:45:33Z","timestamp":1792233933830,"version":"4.4.0"},"reference-count":19,"publisher":"Elsevier BV","issue":"20","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,6]],"date-time":"2018-04-06T00:00:00Z","timestamp":1522972800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U19 AI-082655 to MBS"],"award-info":[{"award-number":["U19 AI-082655 to MBS"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI103055 to JBH"],"award-info":[{"award-number":["AI103055 to JBH"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/j.vaccine.2018.04.011","type":"journal-article","created":{"date-parts":[[2018,4,11]],"date-time":"2018-04-11T12:46:59Z","timestamp":1523450819000},"page":"2768-2773","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Lipopolysaccharide-specific memory B cell responses to an attenuated live cholera vaccine are associated with protection against Vibrio cholerae infection"],"prefix":"10.1016","volume":"36","author":[{"given":"Douglas J.","family":"Haney","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Lock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Gurwith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakub K.","family":"Simon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn","family":"Ishioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell B.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth D.","family":"Kirkpatrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline E.","family":"Lyon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilbur H.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo B.","family":"Sztein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myron M.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason B.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2018.04.011_b0005","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1093\/infdis\/166.4.837","article-title":"Onset and duration of protective immunity in challenged volunteers after vaccination with live oral cholera vaccine CVD 103-HgR","volume":"166","author":"Tacket","year":"1992","journal-title":"J Infect Dis"},{"issue":"12","key":"10.1016\/j.vaccine.2018.04.011_b0010","doi-asserted-by":"crossref","first-page":"6341","DOI":"10.1128\/IAI.67.12.6341-6345.1999","article-title":"Randomized, double-blind, placebo-controlled, multicentered trial of the efficacy of a single dose of live oral cholera vaccine CVD 103-HgR in preventing cholera following challenge with Vibrio cholerae O1 El Tor Inaba three months after vaccination","volume":"67","author":"Tacket","year":"1999","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2018.04.011_b0015","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1093\/cid\/ciw145","article-title":"Single- CVD 103-HgR protects against human experimental infection with Vibrio cholerae O1 El Tor","volume":"62","author":"Chen","year":"2016","journal-title":"Clin Inf Dis"},{"key":"10.1016\/j.vaccine.2018.04.011_b0020","doi-asserted-by":"crossref","first-page":"e00098","DOI":"10.1128\/CVI.00098-17","article-title":"Antibody-based correlates of protection against cholera","volume":"24","author":"Haney","year":"2017","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.vaccine.2018.04.011_b0025","doi-asserted-by":"crossref","first-page":"3850","DOI":"10.1128\/IAI.00369-09","article-title":"Antigen-specific memory B-cell responses to Vibrio cholerae O1 infection in Bangladesh","volume":"77","author":"Harris","year":"2009","journal-title":"Infect Immun"},{"issue":"6","key":"10.1016\/j.vaccine.2018.04.011_b0030","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02021-16","article-title":"Single-cell analysis of the plasmablast response to Vibrio cholerae demonstrates expansion of cross-reactive memory B cells","volume":"7","author":"Kauffman","year":"2016","journal-title":"mBio"},{"key":"10.1016\/j.vaccine.2018.04.011_b0035","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1128\/CVI.00037-12","article-title":"Memory B cell responses to Vibrio cholerae O1 lipopolysaccharide are associated with protection against infection from household contacts of patients with cholera in Bangladesh","volume":"19","author":"Patel","year":"2012","journal-title":"Clin Vaccine Immunol"},{"issue":"1","key":"10.1016\/j.vaccine.2018.04.011_b0040","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1128\/IAI.64.1.10-15.1996","article-title":"Factors influencing secondary vibriocidal immune responses: relevance for understanding immunity to cholera","volume":"64","author":"Losonsky","year":"1996","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2018.04.011_b0045","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jim.2003.12.015","article-title":"Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system","volume":"286","author":"Crotty","year":"2004","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.vaccine.2018.04.011_b0050","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jim.2013.02.009","article-title":"Optimization of a human IgG B-cell ELISpot assay for the analysis of vaccine-induced B-cell responses","volume":"391","author":"Jahnmatz","year":"2013","journal-title":"J Immunol Methods"},{"issue":"7","key":"10.1016\/j.vaccine.2018.04.011_b0055","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1086\/591500","article-title":"Cholera toxin-specific memory B cell responses are induced in patients with dehydrating diarrhea caused by Vibrio cholerae O1","volume":"198","author":"Jayasekera","year":"2008","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2018.04.011_b0060","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.jim.2013.05.007","article-title":"Frahm N and the NIAID HTVTN. Optimization and qualification of a memory B-cell ELISpot for the detection of vaccine-induced memory responses in HIV vaccine trials","volume":"394","author":"Walsh","year":"2013","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.vaccine.2018.04.011_b0065","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S1473-3099(12)70345-6","article-title":"Safety and immunogenicity of an oral, replicating adenovirus serotype 4 vector vaccine for H5N1 influenza: a randomised, double-blind, placebo-controlled, phase 1 study","volume":"13","author":"Gurwith","year":"2013","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.vaccine.2018.04.011_b0070","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1093\/biomet\/26.4.404","article-title":"The use of confidence or fiducial limits illustrated in the case of the binomial","volume":"26","author":"Clopper","year":"1934","journal-title":"Biometrika"},{"issue":"5","key":"10.1016\/j.vaccine.2018.04.011_b0075","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1128\/CVI.00562-10","article-title":"Antigen-specific memory B-cell responses in Bangladeshi adults after one- or two-dose oral killed cholera vaccination and comparison with responses in patients with naturally acquired cholera","volume":"18","author":"Alam","year":"2011","journal-title":"Clin Vaccine Immunol"},{"issue":"10","key":"10.1016\/j.vaccine.2018.04.011_b0080","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1093\/cid\/cit048","article-title":"Complex correlates of protection after vaccination","volume":"56","author":"Plotkin","year":"2013","journal-title":"Clin Infect Dis"},{"issue":"11","key":"10.1016\/j.vaccine.2018.04.011_b0085","doi-asserted-by":"crossref","first-page":"5090","DOI":"10.1128\/IAI.00793-09","article-title":"Memory T-cell responses to Vibrio cholerae O1 infection","volume":"77","author":"Weil","year":"2009","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2018.04.011_b0090","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1128\/IAI.01101-08","article-title":"Cholera caused by Vibrio cholerae O1 induces T-cell responses in the circulation","volume":"77","author":"Bhuiyan","year":"2009","journal-title":"Infect Immun"},{"key":"10.1016\/j.vaccine.2018.04.011_b0095","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.smim.2004.02.008","article-title":"Immunological memory in humans","volume":"16","author":"Crotty","year":"2004","journal-title":"Semin Immunol"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X18304808?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X18304808?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,31]],"date-time":"2020-10-31T14:18:55Z","timestamp":1604153935000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X18304808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":19,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["S0264410X18304808"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2018.04.011","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lipopolysaccharide-specific memory B cell responses to an attenuated live cholera vaccine are associated with protection against Vibrio cholerae infection","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2018.04.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}