{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T06:59:14Z","timestamp":1793775554679,"version":"4.6.1"},"reference-count":41,"publisher":"Elsevier BV","issue":"37","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Medical and Health Science and Technology","award":["2015KYB350"],"award-info":[{"award-number":["2015KYB350"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.vaccine.2018.05.025","type":"journal-article","created":{"date-parts":[[2018,8,10]],"date-time":"2018-08-10T08:32:02Z","timestamp":1533889922000},"page":"5665-5670","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"title":["Varicella breakthrough infection and effectiveness of 2-dose varicella vaccine in China"],"prefix":"10.1016","volume":"36","author":[{"given":"Xingqiang","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingming","family":"Shu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjun","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yexiang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guozhang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2018.05.025_b0005","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1001\/jama.287.5.606","article-title":"Varicella disease after introduction of varicella vaccine in the United States, 1995\u20132000","volume":"287","author":"Seward","year":"2002","journal-title":"Jama"},{"key":"10.1016\/j.vaccine.2018.05.025_b0010","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.tmaid.2013.06.002","article-title":"Epidemiology and impact of varicella vaccination: a longitudinal study 1994\u20132011","volume":"11","author":"Al-Tawfiq","year":"2013","journal-title":"Travel Med Infect Dis"},{"key":"10.1016\/j.vaccine.2018.05.025_b0015","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.1016\/j.vaccine.2014.04.069","article-title":"The epidemiology of varicella cases among children in Beijing's Fengtai District from 2008 to 2012","volume":"32","author":"Zhang","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2018.05.025_b0020","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1056\/NEJMoa064040","article-title":"Loss of vaccine-induced immunity to varicella over time","volume":"356","author":"Chaves","year":"2007","journal-title":"New England J Med"},{"key":"10.1016\/j.vaccine.2018.05.025_b0025","doi-asserted-by":"crossref","first-page":"6186","DOI":"10.1016\/j.vaccine.2012.07.062","article-title":"The epidemiology and risk factors for breakthrough varicella in Beijing Fengtai district","volume":"30","author":"Zhang","year":"2012","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2018.05.025_b0030","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1177\/2051013613515621","article-title":"Successes and challenges in varicella vaccine","volume":"2","author":"Papaloukas","year":"2014","journal-title":"Therap Adv Vaccines"},{"key":"10.1016\/j.vaccine.2018.05.025_b0035","doi-asserted-by":"crossref","first-page":"3427","DOI":"10.1016\/j.vaccine.2016.04.059","article-title":"Development of varicella vaccine in Japan and future prospects","volume":"34","author":"Ozaki","year":"2016","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2018.05.025_b0040","doi-asserted-by":"crossref","first-page":"902","DOI":"10.15585\/mmwr.mm6534a4","article-title":"Epidemiology of varicella during the 2-dose varicella vaccination program - United States, 2005\u20132014","volume":"65","author":"Lopez","year":"2016","journal-title":"MMWR Morbidity Mortality Weekly Report"},{"key":"10.1016\/j.vaccine.2018.05.025_b0045","first-page":"20552","article-title":"Impact of universal two-dose vaccination on varicella epidemiology in Navarre, Spain, 2006 to 2012. Euro surveillance: bulletin Europeen sur les maladies transmissibles =","volume":"18","author":"Garcia Cenoz","year":"2013","journal-title":"Eur Commun Dis Bull"},{"key":"10.1016\/j.vaccine.2018.05.025_b0050","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1097\/INF.0b013e31819c1041","article-title":"An outbreak of varicella in elementary school children with two-dose varicella vaccine recipients\u2013Arkansas, 2006","volume":"28","author":"Gould","year":"2009","journal-title":"Pediatric Inf Dis J"},{"key":"10.1016\/j.vaccine.2018.05.025_b0055","doi-asserted-by":"crossref","unstructured":"Suo L, Lu L, Wang Q, Yang F, Wang X, Pang X, et al. Varicella outbreak in a highly-vaccinated school population in Beijing, China during the voluntary two-dose era. Vaccine; 2017.","DOI":"10.1016\/j.vaccine.2017.06.065"},{"key":"10.1016\/j.vaccine.2018.05.025_b0060","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1093\/infdis\/jiq052","article-title":"Effectiveness of 2 doses of varicella vaccine in children","volume":"203","author":"Shapiro","year":"2011","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2018.05.025_b0065","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2015-2802","article-title":"Varicella vaccine effectiveness in preventing community transmission in the 2-dose era","volume":"137","author":"Perella","year":"2016","journal-title":"Pediatrics"},{"key":"10.1016\/j.vaccine.2018.05.025_b0070","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1097\/INF.0000000000000444","article-title":"Two-dose varicella vaccine effectiveness and rash severity in outbreaks of varicella among public school students","volume":"33","author":"Thomas","year":"2014","journal-title":"Pediatric Infect Dis J"},{"key":"10.1016\/j.vaccine.2018.05.025_b0075","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1093\/oxfordjournals.epirev.a017931","article-title":"Epidemiologic methods in immunization programs","volume":"18","author":"Chen","year":"1996","journal-title":"Epidemiol Rev"},{"key":"10.1016\/j.vaccine.2018.05.025_b0080","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1097\/01.inf.0000109287.97518.67","article-title":"Ten year follow-up of healthy children who received one or two injections of varicella vaccine","volume":"23","author":"Kuter","year":"2004","journal-title":"Pediatric Infect Dis J"},{"key":"10.1016\/j.vaccine.2018.05.025_b0085","doi-asserted-by":"crossref","first-page":"3113","DOI":"10.1080\/21645515.2016.1212795","article-title":"Immunogenicity and safety of different schedules of 2-dose varicella vaccination in China","volume":"12","author":"Deng","year":"2016","journal-title":"Human Vaccines Immunotherap"},{"key":"10.1016\/j.vaccine.2018.05.025_b0090","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1017\/S0950268817000772","article-title":"Epidemiological characteristics of breakthrough varicella infection during varicella outbreaks in Shanghai, 2008\u20132014","volume":"145","author":"Zhu","year":"2017","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.vaccine.2018.05.025_b0095","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0031-3955(05)70212-1","article-title":"Varicella vaccine","volume":"47","author":"Chartrand","year":"2000","journal-title":"Pediatric Clinics North America"},{"key":"10.1016\/j.vaccine.2018.05.025_b0100","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1016\/j.vaccine.2011.01.092","article-title":"Varicella breakthrough infection and vaccine effectiveness in Taiwan","volume":"29","author":"Huang","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2018.05.025_b0105","doi-asserted-by":"crossref","first-page":"e305","DOI":"10.1097\/INF.0b013e31828b7def","article-title":"Primary versus secondary failure after varicella vaccination: implications for interval between 2 doses","volume":"32","author":"Bonanni","year":"2013","journal-title":"Pediatric Infect Dis J"},{"key":"10.1016\/j.vaccine.2018.05.025_b0110","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1093\/infdis\/172.1.217","article-title":"Safety and cellular and humoral immune responses of a booster dose of varicella vaccine 6 years after primary immunization","volume":"172","author":"Watson","year":"1995","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2018.05.025_b0115","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/00006454-199601000-00011","article-title":"Safety and immunogenicity of one vs. two injections of Oka\/Merck varicella vaccine in healthy children","volume":"15","author":"Ngai","year":"1996","journal-title":"Pediatric Infect Dis J"},{"key":"10.1016\/j.vaccine.2018.05.025_b0120","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1097\/INF.0b013e318293308e","article-title":"Decrease in varicella incidence after implementation of the 2-dose recommendation for varicella vaccine in New Hampshire","volume":"32","author":"Daly","year":"2013","journal-title":"Pediatric Infect Dis J"},{"key":"10.1016\/j.vaccine.2018.05.025_b0125","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1093\/infdis\/jiq081","article-title":"Impact of 2-dose vaccination on varicella epidemiology: Connecticut - 2005\u20132008","volume":"203","author":"Kattan","year":"2011","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2018.05.025_b0130","doi-asserted-by":"crossref","first-page":"20552","DOI":"10.2807\/1560-7917.ES2013.18.32.20552","article-title":"Impact of universal two-dose vaccination on varicella epidemiology in Navarre, Spain, 2006 to 2012","volume":"18","author":"Garcia Cenoz","year":"2013","journal-title":"Euro Surveill"},{"key":"10.1016\/j.vaccine.2018.05.025_b0135","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.1016\/j.vaccine.2017.03.044","article-title":"Epidemiology of varicella in Haidian district, Beijing, China-2007-2015","volume":"35","author":"Fu","year":"2017","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2018.05.025_b0140","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1017\/S0950268809990860","article-title":"Modelling the impact of one-dose vs. two-dose vaccination regimens on the epidemiology of varicella zoster virus in Australia","volume":"138","author":"Gao","year":"2010","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.vaccine.2018.05.025_b0145","first-page":"1","article-title":"Prevention of varicella: recommendations of the Advisory Committee on Immunization Practices (ACIP)","volume":"56","author":"Marin","year":"2007","journal-title":"MMWR Recommend Reports: Morbidity Mortality Weekly Report Recommend Reports\/Centers Disease Control"},{"issue":"Suppl 2","key":"10.1016\/j.vaccine.2018.05.025_b0150","doi-asserted-by":"crossref","first-page":"S82","DOI":"10.1086\/522145","article-title":"Varicella vaccine effectiveness in the US vaccination program: a review","volume":"197","author":"Seward","year":"2008","journal-title":"J. Infect Dis"},{"key":"10.1016\/j.vaccine.2018.05.025_b0155","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1056\/NEJM200103293441302","article-title":"The effectiveness of the varicella vaccine in clinical practice","volume":"344","author":"Vazquez","year":"2001","journal-title":"New England J Med"},{"issue":"Suppl 2","key":"10.1016\/j.vaccine.2018.05.025_b0160","doi-asserted-by":"crossref","first-page":"S101","DOI":"10.1086\/522134","article-title":"Challenges to implementing second-dose varicella vaccination during an outbreak in the absence of a routine 2-dose vaccination requirement\u2013Maine, 2006","volume":"197","author":"Parker","year":"2008","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2018.05.025_b0165","doi-asserted-by":"crossref","first-page":"6655","DOI":"10.1016\/j.vaccine.2007.07.010","article-title":"Metaanalysis of vaccine effectiveness in varicella outbreaks","volume":"25","author":"Bayer","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2018.05.025_b0170","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1001\/jama.292.6.704","article-title":"Contagiousness of varicella in vaccinated cases: a household contact study","volume":"292","author":"Seward","year":"2004","journal-title":"Jama"},{"key":"10.1016\/j.vaccine.2018.05.025_b0175","doi-asserted-by":"crossref","first-page":"e1389","DOI":"10.1542\/peds.2012-3303","article-title":"Long-term effectiveness of varicella vaccine: a 14-Year, prospective cohort study","volume":"131","author":"Baxter","year":"2013","journal-title":"Pediatrics"},{"key":"10.1016\/j.vaccine.2018.05.025_b0180","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.4161\/hv.23451","article-title":"Effectiveness of one and two doses of varicella vaccine in preventing laboratory-confirmed cases in children in Navarre Spain","volume":"9","author":"Cenoz","year":"2013","journal-title":"Human Vaccines Immunotherap"},{"key":"10.1016\/j.vaccine.2018.05.025_b0185","doi-asserted-by":"crossref","first-page":"6935","DOI":"10.1016\/j.vaccine.2012.07.076","article-title":"Challenges in confirming a varicella outbreak in the two-dose vaccine era","volume":"30","author":"Mahamud","year":"2012","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2018.05.025_b0190","doi-asserted-by":"crossref","first-page":"3385","DOI":"10.1016\/j.vaccine.2010.02.079","article-title":"Modeling the impact of one- and two-dose varicella vaccination on the epidemiology of varicella and zoster","volume":"28","author":"Brisson","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2018.05.025_b0195","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.vaccine.2009.10.086","article-title":"Comparative varicella vaccine effectiveness during outbreaks in day-care centres","volume":"28","author":"Spackova","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2018.05.025_b0200","doi-asserted-by":"crossref","first-page":"e1070","DOI":"10.1542\/peds.2005-2085","article-title":"One dose of varicella vaccine does not prevent school outbreaks: is it time for a second dose?","volume":"117","author":"Lopez","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.vaccine.2018.05.025_b0205","doi-asserted-by":"crossref","first-page":"e1134","DOI":"10.1542\/peds.2013-0863","article-title":"Impact of a routine two-dose varicella vaccination program on varicella epidemiology","volume":"132","author":"Bialek","year":"2013","journal-title":"Pediatrics"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X18306327?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X18306327?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T10:27:51Z","timestamp":1759400871000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X18306327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":41,"journal-issue":{"issue":"37","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S0264410X18306327"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2018.05.025","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Varicella breakthrough infection and effectiveness of 2-dose varicella vaccine in China","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2018.05.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}