{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:17:24Z","timestamp":1792801044232,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"26","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T00:00:00Z","timestamp":1590192000000},"content-version":"am","delay-in-days":357,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"USDA-NIFA-AFRI"},{"DOI":"10.13039\/100000199","name":"United States Department of Agriculture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007710","name":"University of Connecticut","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.vaccine.2019.05.019","type":"journal-article","created":{"date-parts":[[2019,5,10]],"date-time":"2019-05-10T17:33:42Z","timestamp":1557509622000},"page":"3435-3442","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["The VP1 G-H loop hypervariable epitope contributes to protective immunity against Foot and Mouth Disease Virus in swine"],"prefix":"10.1016","volume":"37","author":[{"given":"Ignacio","family":"Fernandez-Sainz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler D.","family":"Gavitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marla","family":"Koster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Ramirez-Medina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yelitza Y.","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence K.","family":"Silbart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"de Los Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1782-3375","authenticated-orcid":false,"given":"Steven M.","family":"Szczepanek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6209","key":"10.1016\/j.vaccine.2019.05.019_b0005","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/337709a0","article-title":"The three-dimensional structure of foot-and-mouth disease virus at 2.9 \u00c5 resolution","volume":"337","author":"Acharya","year":"1989","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.vaccine.2019.05.019_b0010","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1006\/viro.2001.1096","article-title":"Foot-and-mouth disease virus lacking the VP1 G-H loop: the mutant spectrum uncovers interactions among antigenic sites for fitness gain","volume":"288","author":"Baranowski","year":"2001","journal-title":"Virology"},{"issue":"4","key":"10.1016\/j.vaccine.2019.05.019_b0015","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1128\/JVI.74.4.1641-1647.2000","article-title":"Cell recognition by foot-and-mouth disease virus that lacks the RGD integrin-binding motif: flexibility in aphthovirus receptor usage","volume":"74","author":"Baranowski","year":"2000","journal-title":"J Virol"},{"issue":"1","key":"10.1016\/j.vaccine.2019.05.019_b0020","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1089\/vim.1995.8.11","article-title":"A highly divergent antigenic site of foot-and-mouth disease virus retains its immunodominance","volume":"8","author":"Borrego","year":"1995","journal-title":"Viral Immunol"},{"issue":"4","key":"10.1016\/j.vaccine.2019.05.019_b0025","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.vaccine.2013.12.007","article-title":"Accuracy of traditional and novel serology tests for predicting cross-protection in foot-and-mouth disease vaccinated cattle","volume":"32","author":"Brito","year":"2014","journal-title":"Vaccine"},{"issue":"1\u20132","key":"10.1016\/j.vaccine.2019.05.019_b0030","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S0264-410X(99)00169-3","article-title":"Delineation of a neutralizing subregion within the immunodominant epitope (GH loop) of foot-and-mouth disease virus VP1 which does not contain the RGD motif","volume":"18","author":"Brown","year":"1999","journal-title":"Vaccine"},{"issue":"19","key":"10.1016\/j.vaccine.2019.05.019_b0035","doi-asserted-by":"crossref","first-page":"9798","DOI":"10.1128\/JVI.00577-06","article-title":"Specificity of the VP1 GH loop of Foot-and-Mouth Disease virus for alphav integrins","volume":"80","author":"Burman","year":"2006","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.vaccine.2019.05.019_b0040","first-page":"419","article-title":"The infectivity assay of foot-and-mouth disease virus in pigs","volume":"64","author":"Burrows","year":"1966","journal-title":"J Hyg"},{"key":"10.1016\/j.vaccine.2019.05.019_b0045","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1099\/vir.0.045732-0","article-title":"CD4+ T-cell responses to foot-and-mouth disease virus in vaccinated cattle","volume":"94","author":"Carr","year":"2013","journal-title":"J Gen Virol"},{"issue":"10","key":"10.1016\/j.vaccine.2019.05.019_b0050","doi-asserted-by":"crossref","first-page":"6487","DOI":"10.1128\/JVI.79.10.6487-6504.2005","article-title":"Comparative genomics of foot-and-mouth disease virus","volume":"79","author":"Carrillo","year":"2005","journal-title":"J Virol"},{"issue":"6","key":"10.1016\/j.vaccine.2019.05.019_b0055","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.meegid.2008.08.004","article-title":"Serotype-specific differences in antigenic regions of foot-and-mouth disease virus (FMDV): a comprehensive statistical analysis","volume":"8","author":"Cooke","year":"2008","journal-title":"Infect Genet Evol: J Mol Epidemiol Evol Genet Infect Dis"},{"issue":"17","key":"10.1016\/j.vaccine.2019.05.019_b0060","doi-asserted-by":"crossref","first-page":"3446","DOI":"10.1016\/j.vaccine.2006.02.011","article-title":"Immunopotentiation of a foot-and-mouth disease virus subunit vaccine by interferon alpha","volume":"24","author":"de Avila Botton","year":"2006","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2019.05.019_b0065","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.coviro.2018.02.005","article-title":"The need for improved vaccines against foot-and-mouth disease","volume":"29","author":"de Los Santos","year":"2018","journal-title":"Curr Opin Virol"},{"key":"10.1016\/j.vaccine.2019.05.019_b0070","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.vetmic.2016.12.018","article-title":"Foot-and-mouth disease vaccines","volume":"206","author":"Diaz-San Segundo","year":"2017","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.vaccine.2019.05.019_b0075","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.virol.2016.09.027","article-title":"Combination of Adt-O1Manisa and Ad5-boIFN\u03bb3 induces early protective immunity against foot-and-mouth disease in cattle","volume":"499","author":"Diaz-San Segundo","year":"2016","journal-title":"Virology"},{"key":"10.1016\/j.vaccine.2019.05.019_b0080","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.virol.2016.12.021","article-title":"Adenovirus-vectored foot-and-mouth disease vaccine confers early and full protection against FMDV O1 Manisa in swine","volume":"502","author":"Fernandez-Sainz","year":"2017","journal-title":"Virology"},{"issue":"19","key":"10.1016\/j.vaccine.2019.05.019_b0085","doi-asserted-by":"crossref","first-page":"3428","DOI":"10.1016\/j.vaccine.2010.02.074","article-title":"Marker vaccine potential of a foot-and-mouth disease virus with a partial VP1 G-H loop deletion","volume":"28","author":"Fowler","year":"2010","journal-title":"Vaccine"},{"issue":"Pt 3","key":"10.1016\/j.vaccine.2019.05.019_b0090","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1099\/0022-1317-70-3-625","article-title":"The cell attachment site on foot-and-mouth disease virus includes the amino acid sequence RGD (arginine-glycine-aspartic acid)","volume":"70","author":"Fox","year":"1989","journal-title":"J Gen Virol"},{"issue":"33","key":"10.1016\/j.vaccine.2019.05.019_b0095","doi-asserted-by":"crossref","first-page":"6191","DOI":"10.1016\/j.vaccine.2007.06.002","article-title":"Vaccination of mice with plasmids expressing processed capsid protein of foot-and-mouth disease virus\u2014Importance of dominant and subdominant epitopes for antigenicity and protection","volume":"25","author":"Frimann","year":"2007","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.vaccine.2019.05.019_b0100","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1099\/0022-1317-36-1-59","article-title":"Characteristics of a human cell line transformed by DNA from human adenovirus type 5","volume":"36","author":"Graham","year":"1977","journal-title":"J Gen Virol"},{"issue":"2","key":"10.1016\/j.vaccine.2019.05.019_b0105","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1128\/CMR.17.2.465-493.2004","article-title":"Foot-and-mouth disease","volume":"17","author":"Grubman","year":"2004","journal-title":"Clin Microbiol Rev"},{"issue":"1","key":"10.1016\/j.vaccine.2019.05.019_b0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00705-014-2278-x","article-title":"Three-dimensional structure of foot-and-mouth disease virus and its biological functions","volume":"160","author":"Han","year":"2015","journal-title":"Arch Virol"},{"issue":"4","key":"10.1016\/j.vaccine.2019.05.019_b0115","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1007\/BF01863914","article-title":"Beitrag zur kollektiven Behandlung pharmakologischer Reihenversuche","volume":"162","author":"K\u00e4rber","year":"1931","journal-title":"Naunyn-Schmiedebergs Archiv f\u00fcr experimentelle Pathologie und Pharmakologie"},{"issue":"1","key":"10.1016\/j.vaccine.2019.05.019_b0120","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0168-1702(02)00260-5","article-title":"Molecular epidemiology of foot-and-mouth disease virus","volume":"91","author":"Knowles","year":"2003","journal-title":"Virus Res"},{"issue":"3","key":"10.1016\/j.vaccine.2019.05.019_b0125","doi-asserted-by":"crossref","first-page":"499","DOI":"10.3201\/eid1803.110908","article-title":"Southeast Asian foot-and-mouth disease viruses in Eastern Asia","volume":"18","author":"Knowles","year":"2012","journal-title":"Emerg Infect Dis"},{"issue":"10","key":"10.1016\/j.vaccine.2019.05.019_b0130","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1038\/nsmb.3096","article-title":"Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design","volume":"22","author":"Kotecha","year":"2015","journal-title":"Nat Struct Mol Biol"},{"issue":"6","key":"10.1016\/j.vaccine.2019.05.019_b0135","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1128\/JCM.03370-12","article-title":"A continuous bovine kidney cell line constitutively expressing bovine \u03b1V\u03b26 integrin has increased susceptibility to foot-and-mouth disease virus","volume":"51","author":"LaRocco","year":"2013","journal-title":"J Clin Microbiol"},{"issue":"2","key":"10.1016\/j.vaccine.2019.05.019_b0140","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1128\/JCM.03220-14","article-title":"Correction for LaRocco et al., a continuous bovine kidney cell line constitutively expressing bovine \u03b1V\u03b26 integrin has increased susceptibility to foot-and-mouth disease virus","volume":"53","author":"LaRocco","year":"2015","journal-title":"J Clin Microbiol"},{"issue":"48","key":"10.1016\/j.vaccine.2019.05.019_b0145","doi-asserted-by":"crossref","first-page":"6845","DOI":"10.1016\/j.vaccine.2012.09.011","article-title":"Avidity and subtyping of specific antibodies applied to the indirect assessment of heterologous protection against Foot-and-Mouth Disease Virus in cattle","volume":"30","author":"Lavoria","year":"2012","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.vaccine.2019.05.019_b0150","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.virol.2012.11.001","article-title":"Foot-and-mouth disease virus (FMDV) with a stable FLAG epitope in the VP1 G-H loop as a new tool for studying FMDV pathogenesis","volume":"436","author":"Lawrence","year":"2013","journal-title":"Virology"},{"issue":"3","key":"10.1016\/j.vaccine.2019.05.019_b0155","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1128\/jvi.68.3.1407-1417.1994","article-title":"Antigenic heterogeneity of a foot-and-mouth disease virus serotype in the field is mediated by very limited sequence variation at several antigenic sites","volume":"68","author":"Mateu","year":"1994","journal-title":"J Virol"},{"issue":"3","key":"10.1016\/j.vaccine.2019.05.019_b0160","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1099\/0022-1317-71-3-629","article-title":"A single amino acid substitution affects multiple overlapping epitopes in the major antigenic site of foot-and-mouth disease virus of serotype C","volume":"71","author":"Mateu","year":"1990","journal-title":"J Gen Virol"},{"issue":"1","key":"10.1016\/j.vaccine.2019.05.019_b0165","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/S0042-6822(95)80045-X","article-title":"Direct evaluation of the immunodominance of a major antigenic site of foot-and-mouth disease virus in a natural host","volume":"206","author":"Mateu","year":"1995","journal-title":"Virology"},{"issue":"2","key":"10.1016\/j.vaccine.2019.05.019_b0170","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1006\/viro.1999.9940","article-title":"Development of replication-defective adenovirus serotype 5 containing the capsid and 3C protease coding regions of foot-and-mouth disease virus as a vaccine candidate","volume":"263","author":"Mayr","year":"1999","journal-title":"Virology"},{"issue":"5","key":"10.1016\/j.vaccine.2019.05.019_b0175","doi-asserted-by":"crossref","DOI":"10.2144\/01315st05","article-title":"pAd5-Blue: direct ligation system for engineering recombinant adenovirus constructs","volume":"31","author":"Moraes","year":"2001","journal-title":"BioTechniques"},{"key":"10.1016\/j.vaccine.2019.05.019_b0180","unstructured":"OIE. Manual of diagnostic tests and vaccines for terrestrial animals. Seventh edition. Section 2.1. List A diseases. Chapter 2.1.5 Foot and mouth disease; 2012. pp. 145\u201373."},{"issue":"Pt 6","key":"10.1016\/j.vaccine.2019.05.019_b0185","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1099\/0022-1317-70-6-1493","article-title":"Neutralizing epitopes of type O foot-and-mouth disease virus. II. Mapping three conformational sites with synthetic peptide reagents","volume":"70","author":"Parry","year":"1989","journal-title":"J Gen Virol"},{"issue":"45","key":"10.1016\/j.vaccine.2019.05.019_b0190","doi-asserted-by":"crossref","first-page":"5689","DOI":"10.1016\/j.vaccine.2008.08.022","article-title":"Delivery of a foot-and-mouth disease virus empty capsid subunit antigen with nonstructural protein 2B improves protection of swine","volume":"26","author":"Pena","year":"2008","journal-title":"Vaccine"},{"issue":"20","key":"10.1016\/j.vaccine.2019.05.019_b0195","doi-asserted-by":"crossref","first-page":"12989","DOI":"10.1128\/JVI.79.20.12989-12998.2005","article-title":"Analysis of a foot-and-mouth disease virus type A24 isolate containing an SGD receptor recognition site in vitro and its pathogenesis in cattle","volume":"79","author":"Rieder","year":"2005","journal-title":"J Virol"},{"issue":"Pt 11","key":"10.1016\/j.vaccine.2019.05.019_b0200","doi-asserted-by":"crossref","first-page":"2371","DOI":"10.1099\/vir.0.043521-0","article-title":"Characterization of epitope-tagged foot-and-mouth disease virus","volume":"93","author":"Seago","year":"2012","journal-title":"J Gen Virol"},{"issue":"2","key":"10.1016\/j.vaccine.2019.05.019_b0205","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1006\/viro.1996.0615","article-title":"Antigenically profound amino acid substitutions occur during large population passages of foot-and-mouth disease virus","volume":"225","author":"Sevilla","year":"1996","journal-title":"Virology"},{"issue":"2","key":"10.1016\/j.vaccine.2019.05.019_b0210","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1023\/A:1007993606750","article-title":"The foot and mouth disease virus type O outbreak of 1992 is not related to vaccine strain (O\/R2\/75)","volume":"16","author":"Suryanarayana","year":"1998","journal-title":"Virus Genes"},{"issue":"4","key":"10.1016\/j.vaccine.2019.05.019_b0215","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1128\/CVI.00035-12","article-title":"Xenoepitope substitution avoids deceptive imprinting and broadens the immune response to foot-and-mouth disease virus","volume":"19","author":"Szczepanek","year":"2012","journal-title":"Clin Vacc Immunol: CVI"},{"issue":"2","key":"10.1016\/j.vaccine.2019.05.019_b0220","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/lam.12354","article-title":"Re-emergence of circulatory foot-and-mouth disease virus serotypes Asia1 in Bangladesh and VP1 protein heterogeneity with vaccine strain IND 63\/72","volume":"60","author":"Ullah","year":"2015","journal-title":"Lett Appl Microbiol"},{"issue":"8","key":"10.1016\/j.vaccine.2019.05.019_b0225","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1002\/j.1460-2075.1995.tb07158.x","article-title":"Structure of the major antigenic loop of foot-and-mouth disease virus complexed with a neutralizing antibody: direct involvement of the Arg-Gly-Asp motif in the interaction","volume":"14","author":"Verdaguer","year":"1995","journal-title":"EMBO J"},{"key":"10.1016\/j.vaccine.2019.05.019_b0230","doi-asserted-by":"crossref","DOI":"10.1186\/s12985-015-0246-z","article-title":"How foot-and-mouth disease virus receptor mediates foot-and-mouth disease virus infection","volume":"12","author":"Wang","year":"2015","journal-title":"Virol J"},{"issue":"Pt 7","key":"10.1016\/j.vaccine.2019.05.019_b0235","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1099\/vir.0.040253-0","article-title":"Insertion of type O-conserved neutralizing epitope into the foot-and-mouth disease virus type Asia1 VP1 G-H loop: effect on viral replication and neutralization phenotype","volume":"93","author":"Wang","year":"2012","journal-title":"J Gen Virol"},{"key":"10.1016\/j.vaccine.2019.05.019_b0240","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.virusres.2015.12.013","article-title":"The rescue and evaluation of FLAG and HIS epitope-tagged Asia 1 type foot-and-mouth disease viruses","volume":"213","author":"Yang","year":"2016","journal-title":"Virus Res"},{"issue":"2","key":"10.1016\/j.vaccine.2019.05.019_b0245","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1006\/viro.1995.1519","article-title":"A 10-amino-acid linear sequence of VP1 of foot and mouth disease virus containing B- and T-cell epitopes induces protection in mice","volume":"212","author":"Zamorano","year":"1995","journal-title":"Virology"},{"key":"10.1016\/j.vaccine.2019.05.019_b0250","doi-asserted-by":"crossref","first-page":"60345","DOI":"10.1016\/S2095-3119(18)61916-1","article-title":"Insertion site of FLAG on foot-and-mouth disease virus VP1 G-H loop affects immunogenicity of FLAG","volume":"17","author":"Zhu","year":"2018","journal-title":"J Integ Agric"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X19306334?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X19306334?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T10:33:11Z","timestamp":1759401191000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X19306334"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":50,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S0264410X19306334"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2019.05.019","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The VP1 G-H loop hypervariable epitope contributes to protective immunity against Foot and Mouth Disease Virus in swine","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2019.05.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}