{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T23:37:00Z","timestamp":1772235420670,"version":"3.50.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.vaccine.2019.10.012","type":"journal-article","created":{"date-parts":[[2019,11,3]],"date-time":"2019-11-03T13:23:57Z","timestamp":1572787437000},"page":"318-322","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Effectiveness of repeated influenza vaccination among the elderly population with high annual vaccine uptake rates during the three consecutive A\/H3N2 epidemics"],"prefix":"10.1016","volume":"38","author":[{"given":"Joon Young","family":"Song","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Yun","family":"Noh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Soo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong-Heon","family":"Wie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Keun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Won","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin Woo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun Hee","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung-Hwa","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Suk","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hee Jin","family":"Cheong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woo Joo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2019.10.012_b0005","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1001\/jama.289.2.179","article-title":"Mortality associated with influenza and respiratory syncytial virus in the United States","volume":"289","author":"Thompson","year":"2003","journal-title":"JAMA"},{"key":"10.1016\/j.vaccine.2019.10.012_b0010","series-title":"Textbook of influenza","first-page":"219","article-title":"Human influenza","author":"Nicholson","year":"1998"},{"key":"10.1016\/j.vaccine.2019.10.012_b0015","doi-asserted-by":"crossref","first-page":"e0209643","DOI":"10.1371\/journal.pone.0209643","article-title":"Cost-effectiveness of influenza vaccine strategies for the elderly in South Korea","volume":"14","author":"Yun","year":"2019","journal-title":"PLoS ONE"},{"key":"10.1016\/j.vaccine.2019.10.012_b0020","first-page":"1","article-title":"Prevention and control of influenza with vaccines: recommendations of the advisory committee on immunization practices (ACIP), 2010","volume":"59","author":"Fiore","year":"2010","journal-title":"MMWR Recomm Rep"},{"key":"10.1016\/j.vaccine.2019.10.012_b0025","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1001\/archinte.159.2.182","article-title":"Protection against influenza after annually repeated vaccination: a meta-analysis of serologic and field studies","volume":"159","author":"Beyer","year":"1999","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.vaccine.2019.10.012_b0030","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0140-6736(79)90468-9","article-title":"Assessment of inactivated influenza-A vaccine after three outbreaks of influenza A at Christ's Hospital","volume":"1","author":"Hoskins","year":"1979","journal-title":"Lancet"},{"key":"10.1016\/j.vaccine.2019.10.012_b0035","doi-asserted-by":"crossref","first-page":"14001","DOI":"10.1073\/pnas.96.24.14001","article-title":"Variable efficacy of repeated annual influenza vaccination","volume":"96","author":"Smith","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.vaccine.2019.10.012_b0040","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1016\/j.vaccine.2015.04.012","article-title":"The European I-MOVE multicentre 2013\u20132014 case-control study. Homogeneous moderate influenza vaccine effectiveness against A(H1N1)pdm09 and heterogenous results by country against A(H3N2)","volume":"33","author":"Valenciano","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2019.10.012_b0045","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1093\/cid\/ciw432","article-title":"influenza vaccine effectiveness against antigenically drifted influenza higher than expected in hospitalized adults: 2014\u20132015","volume":"63","author":"Petrie","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2019.10.012_b0050","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1093\/infdis\/jix074","article-title":"Serial vaccination and the antigenic distance hypothesis: effects on influenza vaccine effectiveness during A(H3N2) epidemics in Canada, 2010\u20132011 to 2014\u20132015","volume":"215","author":"Skowronski","year":"2017","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2019.10.012_b0055","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1093\/cid\/ciy202","article-title":"Dose-dependent negative effects of prior multiple vaccinations against influenza A and influenza B among schoolchildren: a study of Kamigoto island in Japan during the 2011\u20132012, 2012\u20132013, and 2013\u20132014 influenza seasons","volume":"67","author":"Saito","year":"2018","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2019.10.012_b0060","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s12916-018-1239-8","article-title":"The impact of repeated vaccination on influenza vaccine effectiveness: a systematic review and meta-analysis","volume":"17","author":"Ramsay","year":"2019","journal-title":"BMC Med"},{"key":"10.1016\/j.vaccine.2019.10.012_b0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/14760584.2017.1334554","article-title":"Repeated annual influenza vaccination and vaccine effectiveness: review of evidence","volume":"16","author":"Belongia","year":"2017","journal-title":"Exp Rev Vacc"},{"key":"10.1016\/j.vaccine.2019.10.012_b0070","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1080\/21645515.2018.1462639","article-title":"H3N2 influenza viruses in humans: viral mechanisms, evolution, and evaluation","volume":"14","author":"Allen","year":"2018","journal-title":"Hum Vaccin Immunother"},{"key":"10.1016\/j.vaccine.2019.10.012_b0075","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1080\/21645515.2017.1367463","article-title":"Strategies in recommending influenza vaccination in Europe and US","volume":"14","author":"Rizzo","year":"2018","journal-title":"Hum Vaccin Immunother"},{"key":"10.1016\/j.vaccine.2019.10.012_b0080","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3947\/ic.2017.49.4.247","article-title":"The Korean influenza national immunization program: history and present status","volume":"49","author":"Yun","year":"2017","journal-title":"Infect Chemother"},{"key":"10.1016\/j.vaccine.2019.10.012_b0085","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1002\/jmv.23548","article-title":"Hospital-based influenza surveillance in Korea: hospital-based influenza morbidity and mortality study group","volume":"85","author":"Song","year":"2013","journal-title":"J Med Virol"},{"key":"10.1016\/j.vaccine.2019.10.012_b0090","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1086\/498119","article-title":"Antibiotic prescription for community-acquired pneumonia in the intensive care unit: impact of adherence to infectious diseases society of America guidelines on survival","volume":"41","author":"Bod\u00ed","year":"2005","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2019.10.012_b0095","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1080\/21645515.2017.1405200","article-title":"Effects of influenza immunization on pneumonia in the elderly","volume":"14","author":"Heo","year":"2018","journal-title":"Hum Vaccin Immunother"},{"key":"10.1016\/j.vaccine.2019.10.012_b0100","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1093\/cid\/cix209","article-title":"Repeated vaccination does not appear to impact upon influenza vaccine effectiveness against hospitalization with confirmed influenza","volume":"64","author":"Cheng","year":"2017","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2019.10.012_b0105","doi-asserted-by":"crossref","first-page":"5556","DOI":"10.1016\/j.vaccine.2018.07.052","article-title":"Impact of repeated influenza vaccinations in persons over 65years of age: a large population-based cohort study of severe influenza over six consecutive seasons, 2011\/12-2016\/17","volume":"36","author":"\u00d6rtqvist","year":"2018","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2019.10.012_b0110","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1093\/cid\/ciu680","article-title":"Impact of repeated vaccination on vaccine effectiveness against influenza A(H3N2) and B during 8 seasons","volume":"59","author":"McLean","year":"2014","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2019.10.012_b0115","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1093\/infdis\/jiu647","article-title":"Influenza vaccine effectiveness in the United States during 2012\u20132013: variable protection by age and virus type","volume":"211","author":"McLean","year":"2015","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2019.10.012_b0120","doi-asserted-by":"crossref","first-page":"e0172059","DOI":"10.1371\/journal.pone.0172059","article-title":"Phylogenetic relationships of the HA and NA genes between vaccine and seasonal influenza A(H3N2) strains in Korea","volume":"12","author":"Kim","year":"2017","journal-title":"PLoS ONE"},{"key":"10.1016\/j.vaccine.2019.10.012_b0125","unstructured":"Korean Center for Infectious Disease Control and Prevention. Korean Influenza Sentinel Surveillance Report, 2014-2015. Public Health Wkly Rep 2016;8:pp. 1096-106."},{"key":"10.1016\/j.vaccine.2019.10.012_b0130","doi-asserted-by":"crossref","first-page":"e0178010","DOI":"10.1371\/journal.pone.0178010","article-title":"Interim estimates of the effectiveness of the influenza vaccine against A(H3N2) influenza in adults in South Korea, 2016\u20132017 season","volume":"12","author":"Noh","year":"2017","journal-title":"PLoS ONE"},{"key":"10.1016\/j.vaccine.2019.10.012_b0135","doi-asserted-by":"crossref","first-page":"5989","DOI":"10.1016\/j.vaccine.2014.07.115","article-title":"The split virus influenza vaccine rapidly activates immune cells through Fcgamma receptors","volume":"32","author":"O'Gorman","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2019.10.012_b0140","unstructured":"Korean Society of Infectious Diseases. Adult vaccinations. 3rd ed. Seoul: Koonja; 2019."},{"key":"10.1016\/j.vaccine.2019.10.012_b0145","doi-asserted-by":"crossref","first-page":"3929","DOI":"10.1016\/j.vaccine.2010.03.067","article-title":"Long-term immunogenicity of influenza vaccine among the elderly: risk factors for poor immune response and persistence","volume":"28","author":"Song","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2019.10.012_b0150","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1186\/s12879-016-1811-9","article-title":"Istanbul Rapid Test Study Group. Analytical performance of the BD veritor system for rapid detection of influenza virus A and B in a primary healthcare setting","volume":"16","author":"Mese","year":"2016","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.vaccine.2019.10.012_b0155","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.diagmicrobio.2014.01.018","article-title":"Prompt detection of influenza A and B viruses using the BD veritor system flu A+B, Quidel(R) Sofia(R) Influenza A+B FIA, and Alere BinaxNOW(R) influenza A&B compared to real-time reverse transcription-polymerase chain reaction (RT-PCR)","volume":"79","author":"Dunn","year":"2014","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.vaccine.2019.10.012_b0160","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1002\/jmv.25043","article-title":"Diagnostic performance of the Sofia(R) influenza A+B fluorescent immunoassay in adult outpatients in Northern Taiwan","volume":"90","author":"Yang","year":"2018","journal-title":"J Med Virol"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X19313751?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X19313751?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T10:37:21Z","timestamp":1759401441000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X19313751"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["S0264410X19313751"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2019.10.012","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effectiveness of repeated influenza vaccination among the elderly population with high annual vaccine uptake rates during the three consecutive A\/H3N2 epidemics","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2019.10.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}