{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T17:42:57Z","timestamp":1790444577538,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"35","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.vaccine.2020.06.076","type":"journal-article","created":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T01:07:50Z","timestamp":1594343270000},"page":"5601-5606","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Varicella vaccination as useful strategy for reducing the risk of varicella-related hospitalizations in both vaccinated and unvaccinated cohorts (Italy, 2003\u20132018)"],"prefix":"10.1016","volume":"38","author":[{"given":"Emanuele","family":"Amodio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5676-9535","authenticated-orcid":false,"given":"Alessandra","family":"Casuccio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Tramuto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Costantino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Marrella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmelo Massimo","family":"Maida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Vitale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5406-884X","authenticated-orcid":false,"given":"Vincenzo","family":"Restivo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.vaccine.2020.06.076_b0005","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1186\/s12889-019-6795-0","article-title":"Burden of varicella in Latin America and the Caribbean: findings from a systematic literature review","volume":"19","author":"Arlant","year":"2019","journal-title":"BMC Public Health"},{"key":"10.1016\/j.vaccine.2020.06.076_b0010","unstructured":"Center for Disease Control and Prevention. CDC Yellow Book (Health Information for International Travel); 2019. https:\/\/wwwnc.cdc.gov\/travel\/yellowbook\/2020\/travel-related-infectious-diseases\/varicella-chickenpox [accessed 10 April 2020]."},{"key":"10.1016\/j.vaccine.2020.06.076_b0015","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1186\/1471-2334-9-150","article-title":"Varicella: epidemiological aspects and vaccination coverage in the Veneto Region","volume":"9","author":"Baldo","year":"2009","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.vaccine.2020.06.076_b0020","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.ajic.2017.07.029","article-title":"Incidence rate of breakthrough varicella observed in healthy children after 1 or 2 doses of varicella vaccine: Results from a meta-analysis","volume":"46","author":"Zhu","year":"2018","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.vaccine.2020.06.076_b0025","unstructured":"EpiCentro \u2013 Portale di epidemiologia per gli operatori sanitari. Varicella; 2020. https:\/\/www.epicentro.iss.it\/varicella\/ [accessed 10 April 2020]."},{"key":"10.1016\/j.vaccine.2020.06.076_b0030","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.vaccine.2017.11.057","article-title":"Early impact of universal varicella vaccination on childhood varicella and herpes zoster hospitalizations in Brazil","volume":"36","author":"Scotta","year":"2018","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2020.06.076_b0035","doi-asserted-by":"crossref","first-page":"63","DOI":"10.4161\/hv.34311","article-title":"Impact of universal vaccination against varicella in Italy: Experiences from eight Italian Regions","volume":"11","author":"Bechini","year":"2015","journal-title":"Hum Vaccin Immunother"},{"key":"10.1016\/j.vaccine.2020.06.076_b0040","doi-asserted-by":"crossref","first-page":"3594","DOI":"10.4161\/hv.34426","article-title":"Hospitalization with varicella and shingles before and after introduction of childhood varicella vaccination in Germany","volume":"10","author":"Siedler","year":"2014","journal-title":"Hum Vaccin Immunother"},{"key":"10.1016\/j.vaccine.2020.06.076_b0045","unstructured":"Ministero della Sanit\u00e0. Decreto Ministeriale 15 dicembre 1990 - Sistema di sorveglianza sulle malattie infettive. Pubblicato nella Gazz. Uff. 8 gennaio 1991, n. 6."},{"key":"10.1016\/j.vaccine.2020.06.076_b0050","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1017\/S0950268802006878","article-title":"Assessment of varicella underreporting in Italy","volume":"128","author":"Ciofi degli Atti","year":"2002","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.vaccine.2020.06.076_b0055","first-page":"E120","article-title":"Impact of vaccination programs against measles, varicella and meningococcus C in Italy and in Tuscany and public health policies in the last decades","volume":"59","author":"Bechini","year":"2018","journal-title":"J Prev Med Hyg"},{"key":"10.1016\/j.vaccine.2020.06.076_b0060","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1007\/s10096-018-3286-7","article-title":"Management of chickenpox in pregnant women: an Italian perspective","volume":"37","author":"Parente","year":"2018","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.vaccine.2020.06.076_b0065","unstructured":"Center for Disease Control and Prevention. About the varicella vaccines; 2020. https:\/\/www.cdc.gov\/vaccines\/vpd\/varicella\/hcp\/about-vaccine.html [accessed 10 April 2020]"},{"key":"10.1016\/j.vaccine.2020.06.076_b0070","doi-asserted-by":"crossref","first-page":"236","DOI":"10.4161\/hv.36157","article-title":"The impact of ten years of infant universal Varicella vaccination in Sicily, Italy (2003\u20132012)","volume":"11","author":"Amodio","year":"2015","journal-title":"Hum Vaccin Immunother"},{"key":"10.1016\/j.vaccine.2020.06.076_b0075","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1099\/jmm.0.000061","article-title":"Burden of varicella in Italy, 2001\u20132010: analysis of data from multiple sources and assessment of universal vaccination impact in three pilot regions","volume":"64","author":"Trucchi","year":"2015","journal-title":"J Med Microbiol"},{"issue":"22","key":"10.1016\/j.vaccine.2020.06.076_b0080","doi-asserted-by":"crossref","first-page":"1800238","DOI":"10.2807\/1560-7917.ES.2018.23.22.1800238","article-title":"Introduction of new and reinforcement of existing compulsory vaccinations in Italy: first evaluation of the impact on vaccination coverage in 2017","volume":"23","author":"D\u2019Ancona","year":"2018","journal-title":"Euro Surveill"},{"issue":"26","key":"10.1016\/j.vaccine.2020.06.076_b0085","doi-asserted-by":"crossref","first-page":"1900371","DOI":"10.2807\/1560-7917.ES.2019.24.26.1900371","article-title":"The law on compulsory vaccination in Italy: an update 2 years after the introduction","volume":"24","author":"D\u2019Ancona","year":"2019","journal-title":"Euro Surveill"},{"key":"10.1016\/j.vaccine.2020.06.076_b0090","unstructured":"Istituto nazionale di statistica (ISTAT). Demografia in cifre; 2020. Available at http:\/\/demo.istat.it\/ [accessed 10 April 2020]."},{"key":"10.1016\/j.vaccine.2020.06.076_b0095","first-page":"231","article-title":"Infant immunization coverage in Italy (2000\u20132016)","volume":"53","author":"Signorelli","year":"2017","journal-title":"Ann Ist Super Sanita"},{"issue":"24","key":"10.1016\/j.vaccine.2020.06.076_b0100","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2016.21.24.30257","article-title":"Preparing to introduce the varicella vaccine into the Italian immunisation programme: varicella-related hospitalisations in Tuscany, 2004\u20132012","volume":"21","author":"Boccalini","year":"2016","journal-title":"Euro Surveill"},{"issue":"3","key":"10.1016\/j.vaccine.2020.06.076_b0105","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1080\/14760584.2017.1247700","article-title":"Varicella prevention in Costa Rica: impact of a one-dose schedule universal vaccination","volume":"16","author":"Avila-Aguero","year":"2017","journal-title":"Expert Rev Vacc"},{"key":"10.1016\/j.vaccine.2020.06.076_b0110","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1186\/1471-2334-13-303","article-title":"Varicella routine vaccination and the effects on varicella epidemiology - results from the Bavarian Varicella Surveillance Project (BaVariPro), 2006\u20132011","volume":"13","author":"Streng","year":"2013","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.vaccine.2020.06.076_b0115","doi-asserted-by":"crossref","first-page":"7043","DOI":"10.1016\/j.vaccine.2014.10.076","article-title":"Varicella vaccination coverage inverse correlation with varicella hospitalizations in Spain","volume":"32","author":"Gil-Prieto","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2020.06.076_b0120","doi-asserted-by":"crossref","first-page":"593","DOI":"10.2471\/BLT.13.132142","article-title":"Varicella and herpes zoster hospitalizations before and after implementation of one-dose varicella vaccination in Australia: an ecological study","volume":"92","author":"Heywood","year":"2014","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.vaccine.2020.06.076_b0125","doi-asserted-by":"crossref","first-page":"4744","DOI":"10.1016\/j.vaccine.2013.08.022","article-title":"The impact of the universal infant varicella immunization strategy on Canadian varicella-related hospitalization rates","volume":"31","author":"Waye","year":"2013","journal-title":"Vaccine"},{"key":"10.1016\/j.vaccine.2020.06.076_b0130","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1136\/adc.2007.126243","article-title":"Impact of universal varicella vaccination on 1-year-olds in Uruguay: 1997\u20132005","volume":"93","author":"Quian","year":"2008","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.vaccine.2020.06.076_b0135","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1080\/21645515.2018.1546525","article-title":"Global impact of varicella vaccination programs","volume":"15","author":"Varela","year":"2019","journal-title":"Hum Vaccin Immunother"},{"key":"10.1016\/j.vaccine.2020.06.076_b0140","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1097\/INF.0b013e318260cc4d","article-title":"The effect of funded varicella immunization programs on varicella-related hospitalizations in IMPACT centers, Canada, 2000\u20132008","volume":"31","author":"Tan","year":"2012","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.vaccine.2020.06.076_b0145","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1542\/peds.68.1.14","article-title":"Age-specific risks of varicella complications","volume":"68","author":"Preblud","year":"1981","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.vaccine.2020.06.076_b0150","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1017\/S0950268818000444","article-title":"The changing epidemiology of varicella and herpes zoster in Hong Kong before universal varicella vaccination in 2014","volume":"146","author":"Chan","year":"2018","journal-title":"Epidemiol Infect"},{"issue":"8","key":"10.1016\/j.vaccine.2020.06.076_b0155","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1080\/14760584.2017.1343669","article-title":"Varicella vaccination \u2013 the global experience","volume":"16","author":"Wutzler","year":"2017","journal-title":"Expert Rev Vacc"},{"issue":"4","key":"10.1016\/j.vaccine.2020.06.076_b0160","first-page":"275","article-title":"Varicella vaccination programs do not seem to shift the age of disease to older age groups","volume":"3","author":"Garc\u00eda","year":"2014","journal-title":"Transl Pediatr"},{"key":"10.1016\/j.vaccine.2020.06.076_b0165","doi-asserted-by":"crossref","first-page":"A683","DOI":"10.1016\/j.jval.2014.08.2554","article-title":"Coverage or efficacy: which factor is the most influential for reducing varicella with routine childhood vaccination in Italy?","volume":"17","author":"Sauboin","year":"2014","journal-title":"Value Health"},{"key":"10.1016\/j.vaccine.2020.06.076_b0170","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1186\/s12889-016-3738-x","article-title":"Coverage, efficacy or dosing interval: which factor predominantly influences the impact of routine childhood vaccination for the prevention of varicella? A model-based study for Italy","volume":"16","author":"Holl","year":"2016","journal-title":"BMC Public Health"},{"key":"10.1016\/j.vaccine.2020.06.076_b0175","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.iedeen.2018.10.001","article-title":"A proposal for a new index to evaluate hospital resource allocation: The case of Italian NHS rationalisation","volume":"25","author":"Marino","year":"2019","journal-title":"Eur Res Manage Bus Econ"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X20308793?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X20308793?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T10:45:06Z","timestamp":1759401906000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X20308793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":35,"journal-issue":{"issue":"35","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["S0264410X20308793"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2020.06.076","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Varicella vaccination as useful strategy for reducing the risk of varicella-related hospitalizations in both vaccinated and unvaccinated cohorts (Italy, 2003\u20132018)","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2020.06.076","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}