{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T06:31:15Z","timestamp":1778999475697,"version":"3.51.4"},"reference-count":61,"publisher":"Elsevier BV","issue":"19","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T00:00:00Z","timestamp":1680566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Vaccine"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.vaccine.2023.03.063","type":"journal-article","created":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T07:24:37Z","timestamp":1680852277000},"page":"3028-3037","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["A systematic review of pneumococcal conjugate vaccine impact on pneumococcal nasopharyngeal colonisation density in children under 5 years of age"],"prefix":"10.1016","volume":"41","author":[{"given":"Isatou","family":"Jagne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"von Mollendorf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashleigh","family":"Wee-Hee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Belinda","family":"Ortika","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Satzke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona M.","family":"Russell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.vaccine.2023.03.063_b0005","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S1473-3099(04)00938-7","article-title":"Streptococcus pneumoniae colonisation: the key to pneumococcal disease","volume":"4","author":"Bogaert","year":"2004","journal-title":"Lancet Infect Dis"},{"issue":"2","key":"10.1016\/j.vaccine.2023.03.063_b0010","doi-asserted-by":"crossref","first-page":"e0212295","DOI":"10.1371\/journal.pone.0212295","article-title":"Effectiveness of pneumococcal conjugate vaccines against invasive pneumococcal disease among children under five years of age in Africa: A systematic review","volume":"14","author":"Ngocho","year":"2019","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.vaccine.2023.03.063_b0015","doi-asserted-by":"crossref","first-page":"p. ofy039","DOI":"10.1093\/ofid\/ofy039","article-title":"Dynamics of Colonization of Streptococcus pneumoniae Strains in Healthy Peruvian Children","volume":"5","author":"Nelson","year":"2018","journal-title":"Open Forum Infect Dis"},{"issue":"4","key":"10.1016\/j.vaccine.2023.03.063_b0020","doi-asserted-by":"crossref","first-page":"e60273","DOI":"10.1371\/journal.pone.0060273","article-title":"Estimating the burden of pneumococcal pneumonia among adults: a systematic review and meta-analysis of diagnostic techniques","volume":"8","author":"Said","year":"2013","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.vaccine.2023.03.063_b0025","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/aje\/154.1.85","article-title":"Interpreting Results from Trials of Pneumococcal Conjugate Vaccines: A Statistical Test for Detecting Vaccine-induced Increases in Carriage of Nonvaccine Serotypes","volume":"154","author":"Lipsitch","year":"2000","journal-title":"Am J Epidemiol"},{"issue":"9693","key":"10.1016\/j.vaccine.2023.03.063_b0030","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/S0140-6736(09)61204-6","article-title":"Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates","volume":"374","author":"O'Brien","year":"2009","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.vaccine.2023.03.063_b0035","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1586\/erv.12.53","article-title":"The fundamental link between pneumococcal carriage and disease","volume":"11","author":"Simell","year":"2012","journal-title":"Expert Rev Vaccines"},{"issue":"7","key":"10.1016\/j.vaccine.2023.03.063_b0040","doi-asserted-by":"crossref","first-page":"e744","DOI":"10.1016\/S2214-109X(18)30247-X","article-title":"Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national estimates for 2000\u201315","volume":"6","author":"Wahl","year":"2018","journal-title":"Lancet Glob Health"},{"issue":"6","key":"10.1016\/j.vaccine.2023.03.063_b0045","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/s41579-018-0001-8","article-title":"Streptococcus pneumoniae: transmission, colonization and invasion","volume":"16","author":"Weiser","year":"2018","journal-title":"Nat Rev Microbiol"},{"issue":"1","key":"10.1016\/j.vaccine.2023.03.063_b0050","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/INF.0b013e3181f111a2","article-title":"Association between nasopharyngeal load of Streptococcus pneumoniae, viral coinfection, and radiologically confirmed pneumonia in Vietnamese children","volume":"30","author":"Vu","year":"2011","journal-title":"Pediatr Infect Dis J"},{"issue":"4","key":"10.1016\/j.vaccine.2023.03.063_b0055","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jinf.2020.06.079","article-title":"Influenza-like illness is associated with high pneumococcal carriage density in Malawian children","volume":"81","author":"Nyazika","year":"2020","journal-title":"J Infect"},{"issue":"5","key":"10.1016\/j.vaccine.2023.03.063_b0060","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/cid\/cir859","article-title":"Use of a rapid test of pneumococcal colonization density to diagnose pneumococcal pneumonia","volume":"54","author":"Albrich","year":"2012","journal-title":"Clin Infect Dis"},{"issue":"12","key":"10.1016\/j.vaccine.2023.03.063_b0065","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1093\/aje\/kwz191","article-title":"Association of Laboratory Methods, Colonization Density, and Age With Detection of Streptococcus pneumoniae in the Nasopharynx","volume":"188","author":"Sutcliffe","year":"2019","journal-title":"Am J Epidemiol"},{"issue":"11","key":"10.1016\/j.vaccine.2023.03.063_b0070","doi-asserted-by":"crossref","first-page":"e339","DOI":"10.1097\/INF.0000000000001266","article-title":"Impact of Haemophilus influenzae Type B Conjugate Vaccines on Nasopharyngeal Carriage in HIV-infected Children and Their Parents from West Bengal, India","volume":"35","author":"Arya","year":"2016","journal-title":"Pediatric Infect Dis J"},{"issue":"10","key":"10.1016\/j.vaccine.2023.03.063_b0075","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1097\/INF.0000000000002134","article-title":"Early Declines in Vaccine Type Pneumococcal Carriage in Children Less Than 5 Years Old After Introduction of 10-valent Pneumococcal Conjugate Vaccine in Mozambique","volume":"37","author":"Sigauque","year":"2018","journal-title":"Pediatr Infect Dis J"},{"issue":"11","key":"10.1016\/j.vaccine.2023.03.063_b0080","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.3201\/eid2211.160902","article-title":"Nasopharyngeal Pneumococcal Density and Evolution of Acute Respiratory Illnesses in Young Children, Peru, 2009\u20132011","volume":"22","author":"Fan","year":"2016","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.vaccine.2023.03.063_b0085","article-title":"Nasopharyngeal Pneumococcal Colonization Density is Associated with Severe Pneumonia in Young Children in the Lao PDR","author":"Carr","year":"2021","journal-title":"J Infect Dis"},{"issue":"suppl_3","key":"10.1016\/j.vaccine.2023.03.063_b0090","doi-asserted-by":"crossref","first-page":"S317","DOI":"10.1093\/cid\/cix100","article-title":"Density of Upper Respiratory Colonization With Streptococcus pneumoniae and Its Role in the Diagnosis of Pneumococcal Pneumonia Among Children Aged <5 Years in the PERCH Study","volume":"64","author":"Baggett","year":"2017","journal-title":"Clin Infect Dis"},{"issue":"10","key":"10.1016\/j.vaccine.2023.03.063_b0095","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1093\/infdis\/jiu326","article-title":"High nasopharyngeal pneumococcal density, increased by viral coinfection, is associated with invasive pneumococcal pneumonia","volume":"210","author":"Wolter","year":"2014","journal-title":"J Infect Dis"},{"issue":"4","key":"10.1016\/j.vaccine.2023.03.063_b0100","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1038\/nrmicro3231","article-title":"The co-pathogenesis of influenza viruses with bacteria in the lung","volume":"12","author":"McCullers","year":"2014","journal-title":"Nat Rev Microbiol"},{"issue":"11","key":"10.1016\/j.vaccine.2023.03.063_b0105","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.3201\/eid2511.190157","article-title":"Nasopharyngeal Pneumococcal Density during Asymptomatic Respiratory Virus Infection and Risk for Subsequent Acute Respiratory Illness","volume":"25","author":"Howard","year":"2019","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.vaccine.2023.03.063_b0110","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/s12879-016-1454-x","article-title":"High pneumococcal density correlates with more mucosal inflammation and reduced respiratory syncytial virus disease severity in infants","volume":"16","author":"Vissers","year":"2016","journal-title":"BMC Infect Dis"},{"issue":"1","key":"10.1016\/j.vaccine.2023.03.063_b0115","doi-asserted-by":"crossref","first-page":"e1154","DOI":"10.1093\/cid\/ciab1014","article-title":"Decline in Pneumococcal Disease in Young Children during the COVID-19 Pandemic in Israel Associated with Suppression of seasonal Respiratory Viruses, despite Persistent Pneumococcal Carriage: A Prospective Cohort Study","volume":"75","author":"Danino","year":"2022","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.vaccine.2023.03.063_b0120","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.3389\/fcimb.2021.825427","article-title":"Infant pneumococcal carriage in Belgium not affected by COVID-19 containment measures","volume":"11","author":"Willen","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"issue":"6","key":"10.1016\/j.vaccine.2023.03.063_b0125","doi-asserted-by":"crossref","first-page":"e2218959","DOI":"10.1001\/jamanetworkopen.2022.18959","article-title":"Association of Nonpharmaceutical Interventions During the COVID-19 Pandemic With Invasive Pneumococcal Disease, Pneumococcal Carriage, and Respiratory Viral Infections Among Children in France","volume":"5","author":"Rybak","year":"2022","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.vaccine.2023.03.063_b0130","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.03615-22","article-title":"Impact of COVID-19 Nonpharmaceutical Interventions on Pneumococcal Carriage Prevalence and Density in Vietnam","author":"Nation","year":"2023","journal-title":"Microbiol Spectrum"},{"issue":"9807","key":"10.1016\/j.vaccine.2023.03.063_b0135","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1016\/S0140-6736(10)62225-8","article-title":"Serotype replacement in disease after pneumococcal vaccination","volume":"378","author":"Weinberger","year":"2011","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.vaccine.2023.03.063_b0140","doi-asserted-by":"crossref","first-page":"e11638","DOI":"10.1371\/journal.pone.0011638","article-title":"Multiple colonization with S. pneumoniae before and after introduction of the seven-valent conjugated pneumococcal polysaccharide vaccine","volume":"5","author":"Brugger","year":"2010","journal-title":"PLoS One"},{"issue":"42","key":"10.1016\/j.vaccine.2023.03.063_b0145","doi-asserted-by":"crossref","first-page":"5708","DOI":"10.1016\/j.vaccine.2015.07.059","article-title":"Long-term impact of pneumococcal polysaccharide vaccination on nasopharyngeal carriage in children previously vaccinated with various pneumococcal conjugate vaccine regimes","volume":"33","author":"Boelsen","year":"2015","journal-title":"Vaccine"},{"issue":"6","key":"10.1016\/j.vaccine.2023.03.063_b0150","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.vaccine.2016.12.052","article-title":"PCV13-vaccinated children still carrying PCV13 additional serotypes show similar carriage density to a control group of PCV7-vaccinated children","volume":"35","author":"Dagan","year":"2017","journal-title":"Vaccine"},{"issue":"10","key":"10.1016\/j.vaccine.2023.03.063_b0155","doi-asserted-by":"crossref","first-page":"e0224392","DOI":"10.1371\/journal.pone.0224392","article-title":"Factors associated with pneumococcal carriage and density in infants and young children in Laos PDR","volume":"14","author":"Dunne","year":"2019","journal-title":"PLoS ONE [Electronic Resource]"},{"issue":"16","key":"10.1016\/j.vaccine.2023.03.063_b0160","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1016\/j.vaccine.2021.02.043","article-title":"Effect of a 2+1 schedule of ten-valent versus 13-valent pneumococcal conjugate vaccine on pneumococcal carriage: Results from a randomised controlled trial in Vietnam","volume":"39","author":"Temple","year":"2021","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.vaccine.2023.03.063_b0165","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1128\/JCM.06589-11","article-title":"Effect of pneumococcal vaccination on nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus in Fijian children","volume":"50","author":"Dunne","year":"2012","journal-title":"J Clin Microbiol"},{"issue":"1","key":"10.1016\/j.vaccine.2023.03.063_b0170","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.vaccine.2013.08.062","article-title":"Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: Updated recommendations from the World Health Organization Pneumococcal Carriage Working Group","volume":"32","author":"Satzke","year":"2013","journal-title":"Vaccine"},{"issue":"6","key":"10.1016\/j.vaccine.2023.03.063_b0175","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1093\/cid\/cis554","article-title":"Effect of age and vaccination with a pneumococcal conjugate vaccine on the density of pneumococcal nasopharyngeal carriage","volume":"55","author":"Roca","year":"2012","journal-title":"Clin Infect Dis"},{"issue":"8","key":"10.1016\/j.vaccine.2023.03.063_b0180","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1086\/521833","article-title":"Effect of Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization among Immunized and Unimmunized Children in a Community\u2010Randomized Trial","volume":"196","author":"O\u2019Brien","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.vaccine.2023.03.063_b0185","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.vacrep.2016.08.002","article-title":"Limited impact of neonatal or early infant schedules of 7-valent pneumococcal conjugate vaccination on nasopharyngeal carriage of Streptococcus pneumoniae in Papua New Guinean children: A randomized controlled trial","volume":"6","author":"Aho","year":"2016","journal-title":"Vaccine Rep"},{"issue":"12","key":"10.1016\/j.vaccine.2023.03.063_b0190","doi-asserted-by":"crossref","first-page":"e1375","DOI":"10.1016\/S2214-109X(18)30383-8","article-title":"Effect of ten-valent pneumococcal conjugate vaccine introduction on pneumococcal carriage in Fiji: results from four annual cross-sectional carriage surveys","volume":"6","author":"Dunne","year":"2018","journal-title":"Lancet Glob Health"},{"issue":"2","key":"10.1016\/j.vaccine.2023.03.063_b0195","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.vaccine.2018.10.077","article-title":"Pneumococcal carriage in vaccine-eligible children and unvaccinated infants in Lao PDR two years following the introduction of the 13-valent pneumococcal conjugate vaccine","volume":"37","author":"Satzke","year":"2019","journal-title":"Vaccine"},{"issue":"30","key":"10.1016\/j.vaccine.2023.03.063_b0200","doi-asserted-by":"crossref","first-page":"4068","DOI":"10.1016\/j.vaccine.2019.05.078","article-title":"Pneumococcal carriage in children in Ulaanbaatar, Mongolia before and one year after the introduction of the 13-valent pneumococcal conjugate vaccine","volume":"37","author":"von Mollendorf","year":"2019","journal-title":"Vaccine"},{"issue":"38","key":"10.1016\/j.vaccine.2023.03.063_b0205","doi-asserted-by":"crossref","first-page":"5401","DOI":"10.1016\/j.vaccine.2021.07.085","article-title":"Lack of effectiveness of 13-valent pneumococcal conjugate vaccination against pneumococcal carriage density in Papua New Guinean infants","volume":"39","author":"Britton","year":"2021","journal-title":"Vaccine"},{"issue":"23","key":"10.1016\/j.vaccine.2023.03.063_b0210","doi-asserted-by":"crossref","first-page":"3278","DOI":"10.1016\/j.vaccine.2018.04.068","article-title":"Evaluation of the association of pneumococcal conjugate vaccine immunization and density of nasopharyngeal bacterial colonization using a multiplex quantitative polymerase chain reaction assay","volume":"36","author":"Olwagen","year":"2018","journal-title":"Vaccine"},{"issue":"12","key":"10.1016\/j.vaccine.2023.03.063_b0215","doi-asserted-by":"crossref","first-page":"O1145","DOI":"10.1111\/1469-0691.12752","article-title":"Density and duration of experimental human pneumococcal carriage","volume":"20","author":"Gritzfeld","year":"2014","journal-title":"Clin Microbiol Infect"},{"issue":"1","key":"10.1016\/j.vaccine.2023.03.063_b0220","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/INF.0b013e318270d850","article-title":"Density interactions among Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in the nasopharynx of young Peruvian children","volume":"32","author":"Chien","year":"2013","journal-title":"Pediatr Infect Dis J"},{"issue":"8","key":"10.1016\/j.vaccine.2023.03.063_b0225","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1128\/JCM.02498-06","article-title":"Evaluation and Improvement of Real-Time PCR Assays Targeting lytA, ply, and psaA Genes for Detection of Pneumococcal DNA","volume":"45","author":"Carvalho","year":"2007","journal-title":"J Clin Microbiol"},{"issue":"1","key":"10.1016\/j.vaccine.2023.03.063_b0230","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-04915-y","article-title":"Comparison of traditional culture and molecular qPCR for detection of simultaneous carriage of multiple pneumococcal serotypes in African children","volume":"7","author":"Olwagen","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.vaccine.2023.03.063_b0235","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ijid.2019.06.024","article-title":"Pneumococcal carriage, density, and co-colonization dynamics: A longitudinal study in Indonesian infants","volume":"86","author":"Murad","year":"2019","journal-title":"Int J Infect Dis"},{"issue":"3","key":"10.1016\/j.vaccine.2023.03.063_b0240","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1128\/CMR.00058-05","article-title":"Insights into the interaction between influenza virus and pneumococcus","volume":"19","author":"McCullers","year":"2006","journal-title":"Clin Microbiol Rev"},{"issue":"2","key":"10.1016\/j.vaccine.2023.03.063_b0245","article-title":"Lethal Synergism between Influenza and Streptococcus pneumoniae","volume":"2","author":"Rudd","year":"2016","journal-title":"J Infect Pulmonary Dis"},{"key":"10.1016\/j.vaccine.2023.03.063_b0250","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1186\/s12879-015-0980-2","article-title":"High multiple carriage and emergence of Streptococcus pneumoniae vaccine serotype variants in Malawian children","volume":"15","author":"Kamng'ona","year":"2015","journal-title":"BMC Infect Dis"},{"issue":"1","key":"10.1016\/j.vaccine.2023.03.063_b0255","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.vaccine.2017.11.052","article-title":"Nasopharyngeal s. pneumoniae carriage and density in Belgian infants after 9 years of pneumococcal conjugate vaccine programme","volume":"36","author":"Wouters","year":"2018","journal-title":"Vaccine"},{"issue":"4","key":"10.1016\/j.vaccine.2023.03.063_b0260","doi-asserted-by":"crossref","first-page":"e0232151","DOI":"10.1371\/journal.pone.0232151","article-title":"Pneumococcal colonization prevalence and density among Thai children with severe pneumonia and community controls","volume":"15","author":"Piralam","year":"2020","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.vaccine.2023.03.063_b0265","doi-asserted-by":"crossref","first-page":"e024856","DOI":"10.1136\/bmjopen-2018-024856","article-title":"Cross-sectional study of the use of antimicrobials following common infections by rural residents in Anhui, China","volume":"9","author":"Chai","year":"2019","journal-title":"BMJ Open"},{"issue":"4","key":"10.1016\/j.vaccine.2023.03.063_b0270","doi-asserted-by":"crossref","first-page":"742","DOI":"10.3390\/microorganisms9040742","article-title":"Global Landscape Review of Serotype-Specific Invasive Pneumococcal Disease Surveillance among Countries Using PCV10\/13: The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) Project","volume":"9","author":"Deloria Knoll","year":"2021","journal-title":"Microorganisms"},{"issue":"2","key":"10.1016\/j.vaccine.2023.03.063_b0275","doi-asserted-by":"crossref","first-page":"e246","DOI":"10.1016\/S2214-109X(21)00405-8","article-title":"Association between household air pollution and nasopharyngeal pneumococcal carriage in Malawian infants (MSCAPE): a nested, prospective, observational study","volume":"10","author":"Dherani","year":"2022","journal-title":"Lancet Glob Health"},{"issue":"12 Suppl 2","key":"10.1016\/j.vaccine.2023.03.063_b0280","doi-asserted-by":"crossref","first-page":"S352","DOI":"10.1093\/infdis\/jiaa535","article-title":"Triumph of Pneumococcal Conjugate Vaccines: Overcoming a Common Foe","volume":"224","author":"Rodgers","year":"2021","journal-title":"J Infect Dis"},{"issue":"10","key":"10.1016\/j.vaccine.2023.03.063_b0285","doi-asserted-by":"crossref","first-page":"e110777","DOI":"10.1371\/journal.pone.0110777","article-title":"Bacterial Load of Pneumococcal Serotypes Correlates with Their Prevalence and Multiple Serotypes Is Associated with Acute Respiratory Infections among Children Less Than 5 Years of Age","volume":"9","author":"Dhoubhadel","year":"2014","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.vaccine.2023.03.063_b0290","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S1473-3099(19)30297-X","article-title":"Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study","volume":"19","author":"Lo","year":"2019","journal-title":"Lancet Infect Dis"},{"issue":"45","key":"10.1016\/j.vaccine.2023.03.063_b0295","doi-asserted-by":"crossref","first-page":"6787","DOI":"10.1016\/j.vaccine.2019.09.038","article-title":"Pneumococcal conjugate vaccine use during humanitarian crises","volume":"37","author":"van Zandvoort","year":"2019","journal-title":"Vaccine"},{"issue":"9","key":"10.1016\/j.vaccine.2023.03.063_b0300","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1128\/IAI.00416-16","article-title":"Infant Mouse Model for the Study of Shedding and Transmission during Streptococcus pneumoniae Monoinfection","volume":"84","author":"Zafar","year":"2016","journal-title":"Infect Immun"},{"issue":"3","key":"10.1016\/j.vaccine.2023.03.063_b0305","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofx161","article-title":"Nasopharyngeal Pneumococcal Density Is Associated With Viral Activity but Not With Use of Improved Stoves Among Young Andean Children","volume":"4","author":"Howard","year":"2017","journal-title":"Open Forum Infect Dis"}],"container-title":["Vaccine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X23003705?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264410X23003705?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T11:24:50Z","timestamp":1759404290000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264410X23003705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":61,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["S0264410X23003705"],"URL":"https:\/\/doi.org\/10.1016\/j.vaccine.2023.03.063","relation":{},"ISSN":["0264-410X"],"issn-type":[{"value":"0264-410X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A systematic review of pneumococcal conjugate vaccine impact on pneumococcal nasopharyngeal colonisation density in children under 5 years of age","name":"articletitle","label":"Article Title"},{"value":"Vaccine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vaccine.2023.03.063","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}