{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T14:34:15Z","timestamp":1762526055190,"version":"build-2065373602"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T00:00:00Z","timestamp":1638403200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary and Animal Science"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.vas.2021.100223","type":"journal-article","created":{"date-parts":[[2021,12,4]],"date-time":"2021-12-04T02:02:30Z","timestamp":1638583350000},"page":"100223","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Impact of general anesthesia on rotational thromboelastometry (ROTEM) parameters and standard plasmatic coagulation tests in healthy Beagle dogs"],"prefix":"10.1016","volume":"14","author":[{"given":"Andrea","family":"Schwarz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise F","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca Del","family":"Chicca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadja E","family":"Sigrist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annette PN","family":"Kutter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.vas.2021.100223_bib0001","doi-asserted-by":"crossref","unstructured":"Adamik, K.-.N., Butty, E., & Howard, J. (2015). In vitro effects of 3% hypertonic saline and 20% mannitol on canine whole blood coagulation and platelet function. BMC Veterinary Research, pp.1\u20139.","DOI":"10.1186\/s12917-015-0555-x"},{"issue":"6","key":"10.1016\/j.vas.2021.100223_bib0002","first-page":"52","article-title":"Viscoelastic testing in cardiac surgery","volume":"60","author":"Agarwal","year":"2020","journal-title":"Transfusion"},{"issue":"3","key":"10.1016\/j.vas.2021.100223_bib0003","doi-asserted-by":"crossref","first-page":"163","DOI":"10.17236\/sat00150","article-title":"Determination of reference intervals and comparison of venous blood gas parameters using a standard and non- standard collection method in 51 dogs","volume":"160","author":"Bachmann","year":"2018","journal-title":"Schweizer Archiv f\u00fcr Tierheilkunde"},{"key":"10.1016\/j.vas.2021.100223_bib0004","doi-asserted-by":"crossref","first-page":"588","DOI":"10.3389\/fvets.2018.00279","article-title":"Hypocoagulability and platelet dysfunction are exacerbated by synthetic colloids in a canine hemorrhagic shock model","volume":"5","author":"Boyd","year":"2018","journal-title":"Frontiers in Veterinary Science"},{"issue":"2","key":"10.1016\/j.vas.2021.100223_bib0005","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/vec.12697","article-title":"In vitro assessment of the effect of acidemia on coagulation in dogs","volume":"28","author":"Burton","year":"2018","journal-title":"Journal of Veterinary Emergency and Critical Care"},{"issue":"2","key":"10.1016\/j.vas.2021.100223_bib0006","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1467-2995.2010.00589.x","article-title":"Effects of 6% hetastarch (600\/0.75) or lactated Ringer's solution on hemostatic variables and clinical bleeding in healthy dogs anesthetized for orthopedic surgery","volume":"38","author":"Chohan","year":"2011","journal-title":"Veterinary Anaesthesia and Analgesia"},{"key":"10.1016\/j.vas.2021.100223_bib0007","doi-asserted-by":"crossref","unstructured":"Cundrle Jr., I. et\u00a0al., (2013).Temperature corrected thromboelastography in hypothermia. Is it necessary?European Journal of Anaesthesiology, 30(2), pp.85\u201389.","DOI":"10.1097\/EJA.0b013e32835c3716"},{"key":"10.1016\/j.vas.2021.100223_bib38","doi-asserted-by":"crossref","first-page":"463","DOI":"10.2460\/ajvr.77.5.463","article-title":"Perfusion- and diffusion-weighted magnetic resonance imaging of the liver of healthy dogs","volume":"77","author":"Del Chicca","year":"2016","journal-title":"American Journal of Veterinary Research"},{"key":"10.1016\/j.vas.2021.100223_bib0008","first-page":"711","article-title":"Correlation of plasma coagulation tests and fibrinogen clausswith rotational thromboelastometry parameters and prediction of bleeding in dogs","volume":"96","author":"Enk","year":"2018","journal-title":"Journal of Veterinary Internal Medicine"},{"issue":"1","key":"10.1016\/j.vas.2021.100223_bib0009","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/vec.12142","article-title":"Systematic evaluation of evidence on veterinary viscoelastic testing Part 2: Sample acquisition and handling","volume":"24","author":"Flatland","year":"2014","journal-title":"Journal of Veterinary Emergency and Critical Care"},{"issue":"2","key":"10.1016\/j.vas.2021.100223_bib0010","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/jvim.14639","article-title":"Thromboelastography in Dogs with Chronic Hepatopathies","volume":"31","author":"Fry","year":"2017","journal-title":"Journal of Veterinary Internal Medicine"},{"issue":"12","key":"10.1016\/j.vas.2021.100223_bib0011","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1160\/TH09-03-0199","article-title":"Fibrin network structure and clot mechanical properties are altered by incorporation of erythrocytes","volume":"102","author":"Gersh","year":"2017","journal-title":"Thrombosis and Haemostasis"},{"issue":"1","key":"10.1016\/j.vas.2021.100223_bib0012","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1757-7241-21-56","article-title":"Changes in fibrinogen availability and utilization in an animal model of traumatic coagulopathy","volume":"21","author":"Hagemo","year":"2013","journal-title":"Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine,"},{"issue":"05","key":"10.1016\/j.vas.2021.100223_bib0013","first-page":"6","article-title":"Serial evaluation of haemostasis following acute trauma using rotational thromboelastometry in dogs","volume":"29","author":"Herrero","year":"2020","journal-title":"Veterinary and Comparative Orthopaedics and Traumatology"},{"key":"10.1016\/j.vas.2021.100223_bib0014","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.rvsc.2020.01.014","article-title":"Determination of reference intervals for single vial rotational thromboelastometry (ROTEM) parameters and correlation with plasmatic coagulation times in 49 clinically healthy dogs","volume":"129","author":"Jud Schefer","year":"2020","journal-title":"Research in Veterinary Science"},{"issue":"4","key":"10.1016\/j.vas.2021.100223_bib0015","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1111\/jvim.13441","article-title":"Thromboelastographic evaluation of dogs with acute liver disease","volume":"29","author":"Kelley","year":"2015","journal-title":"Journal of Veterinary Internal Medicine"},{"issue":"4","key":"10.1016\/j.vas.2021.100223_bib0016","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1939-165X.2010.00263.x","article-title":"Application of thrombelastography\/thromboelastometry to veterinary medicine","volume":"39","author":"Kol","year":"2010","journal-title":"Veterinary Clinical Pathology"},{"key":"10.1016\/j.vas.2021.100223_bib0017","first-page":"292","article-title":"The influence of propofol and sevoflurane on hemostasis: A rotational thromboelastographic study","volume":"9","author":"Koo","year":"2014","journal-title":"Anesthesia Pain Medicine"},{"issue":"4","key":"10.1016\/j.vas.2021.100223_bib0018","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/vec.12979","article-title":"The influence of packed cell volume versus plasma proteins on thromboelastographic variables in canine blood","volume":"30","author":"Lynch","year":"2020","journal-title":"Journal of Veterinary Emergency and Critical Care"},{"issue":"5","key":"10.1016\/j.vas.2021.100223_bib0019","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1097\/SLA.0b013e3180cc2e94","article-title":"Acidosis and Coagulopathy","volume":"246","author":"Martini","year":"2007","journal-title":"Annals of Surgery"},{"issue":"3","key":"10.1016\/j.vas.2021.100223_bib0020","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/pan.12106","article-title":"Effect of rapid fluid resuscitation using crystalloids or colloids on hemostasis in piglets","volume":"23","author":"Mauch","year":"2013","journal-title":"B. Anderson, ed. Pediatric Anesthesia,"},{"issue":"2","key":"10.1016\/j.vas.2021.100223_bib0021","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/vcp.12127","article-title":"In vitro hypercoagulability on whole blood thromboelastometry associated with in vivo reduction of circulating red cell mass in dogs","volume":"43","author":"McMichael","year":"2014","journal-title":"Veterinary Clinical Pathology"},{"issue":"1","key":"10.1016\/j.vas.2021.100223_bib0022","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.injury.2011.11.016","article-title":"Effect of hypothermia on coagulatory function and survival in Sprague\u2013Dawley rats exposed to uncontrolled haemorrhagic shock","volume":"44","author":"Park","year":"2013","journal-title":"Injury"},{"issue":"3","key":"10.1016\/j.vas.2021.100223_bib0023","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1111\/j.1476-4431.2012.00730.x","article-title":"Effects of rest temperature, contact activation, and sample technique on canine thrombelastography","volume":"22","author":"Ralph","year":"2012","journal-title":"Journal of Veterinary Emergency and Critical Care"},{"issue":"6","key":"10.1016\/j.vas.2021.100223_bib0024","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1097\/MBC.0b013e32832dc327","article-title":"Effects of acidosis, alkalosis, hyperthermia and hypothermia on haemostasis: Results of point of care testing with the thromboelastography analyser","volume":"20","author":"Ramaker","year":"2009","journal-title":"Blood Coagulation & Fibrinolysis"},{"issue":"1","key":"10.1016\/j.vas.2021.100223_bib0025","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/vec.12556","article-title":"Comparison of the effects of a balanced crystalloid-based and a saline-based tetrastarch solution on canine whole blood coagulation and platelet function","volume":"27","author":"Reuteler","year":"2016","journal-title":"Journal of Veterinary Emergency and Critical Care"},{"issue":"5","key":"10.1016\/j.vas.2021.100223_bib0026","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1213\/ane.0b013e31817ee955","article-title":"A Thromboelastometric Evaluation of the Effects of Hypothermia on the Coagulation System","volume":"107","author":"Rundgren","year":"2008","journal-title":"Anesthesia & Analgesia"},{"issue":"60","key":"10.1016\/j.vas.2021.100223_bib0027","first-page":"33","article-title":"Viscoelastic monitoring in trauma resuscitation","author":"Sayce","year":"2020","journal-title":"Transfusion"},{"issue":"4","key":"10.1016\/j.vas.2021.100223_bib0028","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1111\/jvim.14723","article-title":"Hyperfibrinolysis and Hypofibrinogenemia Diagnosed With Rotational Thromboelastometry in Dogs Naturally Infected With Angiostrongylus vasorum","volume":"31","author":"Sigrist","year":"2017","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"10.1016\/j.vas.2021.100223_bib0029","doi-asserted-by":"crossref","unstructured":"Smith, S.A. e.t al., (2010).Clot formation in canine whole blood as measured by rotational thromboelastometry is influenced by sample handling and coagulation activator. Blood Coagulation & Fibrinolysis, pp. 1\u201311.","DOI":"10.1097\/MBC.0b013e32833e9c47"},{"issue":"6","key":"10.1016\/j.vas.2021.100223_bib0030","doi-asserted-by":"crossref","first-page":"789","DOI":"10.2460\/ajvr.73.6.789","article-title":"Correlation of hematocrit, platelet concentration, and plasma coagulation factors with results of thromboelastometry in canine whole blood samples","volume":"73","author":"Smith","year":"2012","journal-title":"American Journal of Veterinary Research"},{"issue":"8","key":"10.1016\/j.vas.2021.100223_bib0031","doi-asserted-by":"crossref","first-page":"959","DOI":"10.2460\/ajvr.1976.37.08.959","article-title":"Effect of halothane and halothane-nitrous oxide on hematocrit and plasma protein concentration in dog and monkey","volume":"37","author":"Steffey","year":"1976","journal-title":"American Journal of Veterinary Research"},{"issue":"2","key":"10.1016\/j.vas.2021.100223_bib0032","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1476-4431.2012.00729.x","article-title":"In vitro evaluation of the effect of hypothermia on coagulation in dogs via thromboelastography","volume":"22","author":"Taggart","year":"2012","journal-title":"Journal of Veterinary Emergency and Critical Care"},{"issue":"4","key":"10.1016\/j.vas.2021.100223_bib0033","doi-asserted-by":"crossref","first-page":"567","DOI":"10.2460\/ajvr.74.4.567","article-title":"In vitro effects of lipid emulsion on platelet function and thromboelastography in canine blood samples","volume":"74","author":"Tonkin","year":"2013","journal-title":"American Journal of Veterinary Research"},{"issue":"5","key":"10.1016\/j.vas.2021.100223_bib0034","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1111\/vaa.12021","article-title":"Acid\u2013base and electrolyte balance following administration of three crystalloid solutions in dogs undergoing elective orthopaedic surgery","volume":"40","author":"West","year":"2013","journal-title":"Veterinary Anaesthesia and Analgesia"},{"issue":"6","key":"10.1016\/j.vas.2021.100223_bib0035","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1097\/01.TA.0000064328.97941.FC","article-title":"A systematic evaluation of the effect of temperature on coagulation enzyme activity and platelet function","volume":"56","author":"Wolberg","year":"2004","journal-title":"The Journal of Trauma: Injury, Infection, and Critical Care"},{"issue":"4","key":"10.1016\/j.vas.2021.100223_bib0036","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/vec.12320","article-title":"Comparison of the in vitro effects of saline, hypertonic hydroxyethyl starch, hypertonic saline, and two forms of hydroxyethyl starch on whole blood coagulation and platelet function in dogs","volume":"25","author":"Wurlod","year":"2015","journal-title":"Journal of Veterinary Emergency and Critical Care"},{"issue":"4","key":"10.1016\/j.vas.2021.100223_bib0037","doi-asserted-by":"crossref","first-page":"e60415","DOI":"10.1371\/journal.pone.0060415","article-title":"Volatile anesthetics, not intravenous anesthetic propofol bind to and attenuate the activation of platelet receptor integrin \u03b1IIb\u03b23 S. Cheng, ed","volume":"8","author":"Yuki","year":"2013","journal-title":"PloS one"}],"container-title":["Veterinary and Animal Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451943X21000582?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451943X21000582?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T14:30:37Z","timestamp":1762525837000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2451943X21000582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":38,"alternative-id":["S2451943X21000582"],"URL":"https:\/\/doi.org\/10.1016\/j.vas.2021.100223","relation":{},"ISSN":["2451-943X"],"issn-type":[{"type":"print","value":"2451-943X"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of general anesthesia on rotational thromboelastometry (ROTEM) parameters and standard plasmatic coagulation tests in healthy Beagle dogs","name":"articletitle","label":"Article Title"},{"value":"Veterinary and Animal Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vas.2021.100223","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100223"}}