{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T19:39:22Z","timestamp":1793129962626,"version":"4.5.0"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T00:00:00Z","timestamp":1785110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary and Animal Science"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.vas.2026.100786","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T23:32:41Z","timestamp":1785195161000},"page":"100786","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Immature platelet and reticulocyte fractions as dynamic biomarkers of bone marrow activation in dogs and humans: a comprehensive review"],"prefix":"10.1016","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8281-3720","authenticated-orcid":false,"given":"Mahmood","family":"Ahmadi-hamedani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimia","family":"Satari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.vas.2026.100786_bib0001","first-page":"1146","article-title":"Usefulness of measuring reticulated platelets in thrombocytopenia","volume":"99","author":"Abe","year":"2008","journal-title":"Thrombosis and Haemostasis"},{"issue":"4","key":"10.1016\/j.vas.2026.100786_bib0002","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.thromres.2005.09.007","article-title":"A simple technique to determine thrombopoiesis level using immature platelet fraction","volume":"118","author":"Abe","year":"2006","journal-title":"Thrombosis Research"},{"issue":"4","key":"10.1016\/j.vas.2026.100786_bib0003","doi-asserted-by":"crossref","first-page":"617","DOI":"10.32598\/IJVM.19.4.1005711","article-title":"A review of IRF and RMI in evaluating regenerative and non-regenerative anemia in dogs and cats","volume":"19","author":"Ahmadi-Hamedani","year":"2025","journal-title":"Iranian Journal of Veterinary Medicine"},{"issue":"1","key":"10.1016\/j.vas.2026.100786_bib0004","article-title":"Iron-limited erythropoiesis in dogs and cats: A systematic review and meta-analysis of current evidence examining mean corpuscular volume, mean reticulocyte volume, and reticulocyte hemoglobin content","volume":"39","author":"Ahmadi-Hamedani","year":"2025","journal-title":"Journal of Veterinary Internal Medicine"},{"issue":"3","key":"10.1016\/j.vas.2026.100786_bib0005","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1751-553X.2009.01160.x","article-title":"Quality counts: New parameters in blood cell counting","volume":"31","author":"Briggs","year":"2009","journal-title":"International Journal of Laboratory Hematology"},{"issue":"1","key":"10.1016\/j.vas.2026.100786_bib0006","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/j.1365-2141.2004.04987.x","article-title":"Assessment of an immature platelet fraction (IPF) in peripheral thrombocytopenia","volume":"126","author":"Briggs","year":"2004","journal-title":"British Journal of Haematology"},{"issue":"3","key":"10.1016\/j.vas.2026.100786_bib0008","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/ijlh.13177","article-title":"Reticulated platelets and immature platelet fraction: Clinical applications and method limitations","volume":"42","author":"Buttarello","year":"2020","journal-title":"International Journal of Laboratory Hematology"},{"issue":"5","key":"10.1016\/j.vas.2026.100786_bib0009","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1111\/jvim.13598","article-title":"Evaluation of iron deficiency using reticulocyte indices in dogs enrolled in a blood donor program","volume":"29","author":"Foy","year":"2015","journal-title":"Journal of Veterinary Internal Medicine"},{"issue":"8","key":"10.1016\/j.vas.2026.100786_bib0010","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1515\/cclm-2014-0165","article-title":"Reticulated platelets: Analytical aspects and clinical utility","volume":"52","author":"Hoffmann","year":"2014","journal-title":"Clinical Chemistry and Laboratory Medicine (CCLM)"},{"issue":"6","key":"10.1016\/j.vas.2026.100786_bib0011","first-page":"2592","article-title":"Clinical utility of immature reticulocyte fraction for identifying early red blood cell regeneration in anemic dogs","volume":"37","author":"Jung","year":"2023","journal-title":"Journal of Veterinary Internal Medicine"},{"issue":"3","key":"10.1016\/j.vas.2026.100786_bib0013","first-page":"204","article-title":"Reference intervals for reticulocyte indices, immature reticulocyte fraction, and the percentage of hypochromic red blood cells in adult large breed dogs using the ADVIA 2120 hematology analyzer","volume":"52","author":"Moloney","year":"2023","journal-title":"Veterinary Clinical Pathology"},{"issue":"4","key":"10.1016\/j.vas.2026.100786_bib0014","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.bjhh.2016.07.001","article-title":"Determination of reference ranges for immature platelet and reticulocyte fractions and reticulocyte hemoglobin equivalent","volume":"38","author":"Morkis","year":"2016","journal-title":"Revista Brasileira de Hematologia e Hemoterapia"},{"issue":"3","key":"10.1016\/j.vas.2026.100786_bib0015","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1111\/jvim.17074","article-title":"Utility of immature platelet fraction in the Sysmex XN-1000V for the differential diagnosis of central and peripheral thrombocytopenia in dogs and cats","volume":"38","author":"P\u00e9rez-Ecija","year":"2024","journal-title":"Journal of Veterinary Internal Medicine"},{"issue":"1","key":"10.1016\/j.vas.2026.100786_bib0016","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.cll.2014.10.004","article-title":"Clinical utility of reticulocyte parameters","volume":"35","author":"Piva","year":"2015","journal-title":"Clinics in Laboratory Medicine"},{"issue":"1","key":"10.1016\/j.vas.2026.100786_bib0018","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/vcp.12219","article-title":"The utility of reticulocyte indices in distinguishing iron deficiency anemia from anemia of inflammatory disease, portosystemic shunting, and breed-associated microcytosis in dogs","volume":"44","author":"Schaefer","year":"2015","journal-title":"Veterinary Clinical Pathology"},{"issue":"1","key":"10.1016\/j.vas.2026.100786_bib0019","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1939-165X.2005.tb00004.x","article-title":"Hematologic and biochemical abnormalities indicating iron deficiency are associated with decreased reticulocyte hemoglobin content (CHr) and reticulocyte volume (rMCV) in dogs","volume":"34","author":"Steinberg","year":"2005","journal-title":"Veterinary Clinical Pathology"},{"issue":"10","key":"10.1016\/j.vas.2026.100786_bib0020","first-page":"1641","article-title":"Novel hematological parameters for the evaluation of patients with myeloproliferative neoplasms: The immature platelet and reticulocyte fractions","volume":"96","author":"Strati","year":"2017","journal-title":"Annals of Hematology"}],"container-title":["Veterinary and Animal Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451943X26002164?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451943X26002164?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T19:31:04Z","timestamp":1793129464000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2451943X26002164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":17,"alternative-id":["S2451943X26002164"],"URL":"https:\/\/doi.org\/10.1016\/j.vas.2026.100786","relation":{},"ISSN":["2451-943X"],"issn-type":[{"value":"2451-943X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immature platelet and reticulocyte fractions as dynamic biomarkers of bone marrow activation in dogs and humans: a comprehensive review","name":"articletitle","label":"Article Title"},{"value":"Veterinary and Animal Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.vas.2026.100786","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100786"}}